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Anti-cytomegalovirus antibodies and other atherosclerosis risk factors in patients with cardiovascular diseases

Journal of Geriatric Cardiology 2007年第3期4卷 131-134页

作者： Jan Kazar Elena Kovacova Viera Mongiellova martin gajdos Jan Tomka Roman Slysko Viliam Fridrich Slovak Medical University BratislavaSlovak Republic Institute of Virology Slovak Academy of SciencesBratislavaSlovak Republic National Institute of Cardiovascular Diseases BratislavaSlovak Republic

Objective To determine anti-cytomegalovirus(CMV) antibodies along with anti-Chlamydia pneumoniae(CP) antibodies in comparison with inflammatory markers and other risk factors of atherosclerosis in patients with selected cardiovascular diseases(CVD) . Methods A total of 228 patients with coronary heart disease(CHD) and/or hyperten-sion(HT) ,and those who underwent reconstructive vascular surgery(RVS) on carotids or abdominal aorta were tested for the presence of anti-CMV IgG and IgM antibodies as well as for anti-CP IgA antibodies,C-reactive protein(CRP) ,and interleukin-6(IL-6) . Other risk factors for atherosclerosis,namely age,gender,smoking,hypercholesterolemia,and diabetes mellitus were also analyzed. Results Anti-CMV IgG antibodies were found in 204 patients sera(89.5%) ,compared with 46 positive of 68 sera in the controls(67.6%) ,whereas anti-CMV IgM antibodies were detected in 4 of 54 sera of patients tested(7.4%) ,but not in the controls. The highest proportion of positive sera with not only anti-CMV IgG antibodies(95.6.7%) ,but also anti-CP IgA antibodies(78.3%) ,IL-6(84.8%) and CRP(97.8%) ,was observed in patients with RVS. The results obtained corresponded to age,hypercholesterolemia,and diabetes. Conclusions The presence of anti-CMV antibodies together with antibodies to CP and markers of inflammation(CRP and IL-6) in our study was associated with CVD,primarily in elderly patients who underwent RVS.

关键词： cytomegalovirus chlamydia pneumoniae antibodies inflammatory factor atherosclerosis cardiovascular disease

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Period variations of Algol-type eclipsing binaries AD And, TW Cas and IV Cas

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Research in Astronomy and Astrophysics 2018年第4期18卷 115-122页

作者： Stefan Parimucha Pavol gajdos Viktor Kudak Miroslav Fedurco martin Vanko Institute of Physics Faculty of Science University of E J. Safarik 044 01 Kosice Slovakia Astronomical Institute Slovak Academy of Sciences 059 60 Tatranska Lomnica Slovakia

We present new analyses of variations in O-C diagrams of three Algol-type eclipsing binary stars：AD And,TW Cas and IV Cas.We have used all published minima times（including visual and photographic）as well as newly determined ones from our and Super Wasp observations.We determined orbital parameters of 3^（rd） bodies in the systems with statistically significant errors,using our code based on genetic algorithms and Markov chain Monte Carlo simulations.We confirmed the multiple nature of AD And and the triple-star model of TW Cas,and we proposed a quadruple-star model of IV Cas.

关键词： binaries close — binaries eclipsing — techniques photometric — stars individual（AD And TW Cas IV Cas）

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