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Pure and mixed plantations of Persian walnut (Juglans regia L.) for high quality timber production in Chile, South America

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Journal of Plant Ecology 2020年第1期13卷 12-19页

作者： Verónica Loewe-Muñoz Mónica Balzarini marta ortega González Chilean Forest Institute(INFOR) Metropolitan OfficeSucre 2397ÑuñoaSantiagoChile CONICET Biometry Unit College of AgricultureUniversidad Nacional de CórdobaCiudad UniversitariaCC509CP 5000CórdobaArgentina Chilean Forest Institute(INFOR) Biobío OfficeCamino a Coronel Km 7.5San Pedro de la PazConcepciónChile

Aims Persian walnut(Juglans regia L.),an interesting forest species for the veneering industry,requires adequate management to produce valuable high-quality *** species associations and management level can improve stand productivity,the novelty of this work was to assess Persian walnut performance in different planting mixtures and in pure plantations conditioned to management *** Growth,straightness and survival measurements were taken annually for 7 years after planting pure and mixed plantations under two contrasting management *** were recorded at Age 7 in all *** each management intensity,besides the monoculture,three mixtures were tested:a mixture of only main forest species,main forest species plus one arboreal companion species,Black alder(Alnus glutinosa L.)and main species plus the shrub Russian olive(Elaeagnus angustifolia L.)as nurse species.A test of interaction between plantation type and management scenario was conducted using repeated growth *** Findings The interaction was significant,indicating the presence of different mechanisms underlying plantation effects under high and low management *** with pure plantations,Persian walnut associated with the nurse shrub exhibited 78%higher height and 53%higher diameter growth in plantations under low *** benefits(lower presence of walnut blight than in the monoculture)and better straightness were also found in the association including the shrub when the management intensity was not *** beneficial effects in the presence of Russian olive were not present under high management intensity(irrigation,fertilization,tutoring and frequent pruning).Site-specific designs for Persian walnut plantations would depend on the foreseen management intensity.

关键词： noble wood monoculture forest associations companion species Russian olive

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Constructive thinking,rational intelligence and irritable bowel syndrome

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World Journal of Gastroenterology 2009年第25期15卷 3106-3113页

作者： Enrique Rey marta Moreno ortega Monica Olga Garcia Alonso Manuel Diaz-Rubio Department of Digestive Diseases Hospital Clinico San Carlos (IMSALUD)and Faculty of MedicineComplutense University

AIM： To evaluate rational and experiential intelligence in irritable bowel syndrome （IBS） sufferers. METHODS： We recruited 100 subjects with IBS as per Rome 11 criteria （50 consulters and 50 non-consulters） and 100 healthy controls, matched by age, sex and educational level. Cases and controls completed a clinical questionnaire （including symptom characteristics and medical consultation） and the following tests： rational- intelligence （Wechsler Adult Intelligence Scale, 3rd edition）; experiential-intelligence （Constructive Thinking Inventory）; personality （NEO personality inventory）; psychopathology （MMPI-2）, anxiety （state-trait anxiety inventory） and life events （social readjustment rating scale）. Analysis of variance was used to compare the test results of IBS-sufferers and controls, and a logistic regression model was then constructed and adjusted for age, sex and educational level to evaluate any possible association with IBS. RESULTS： No differences were found between IBS cases and controls in terms of IQ （102.0 ± 10.8 vs 102.8 ± 12.6）, but IBS sufferers scored significantly lower in global constructive thinking （43.7± 9.4 vs 49.6 ± 9.7）. In the logistic regression model, global constructive thinking score was independently linked to suffering from IBS [OR 0.92 （0.87-0.97）], without significant OR for total IQ. CONCLUSION： IBS subjects do not show lower rational intelligence than controls, but lower experiential intelligence is nevertheless associated with IBS.

关键词： Constructive thinking Intelligence tests Intelligence Irritable bowel syndrome

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International NeuroAIDS: prospects of HIV-1 associated neurological com-plications

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Cell Research 2005年第Z1期15卷 962-969页

作者： J Roberto TRUJILLO Gilberto JARAMILLO-RANGEL marta ortega-MARTINEZ Augusto C PENALVA de OLIVEIRA Jose E VIDAL Joseph BRYANT Robert C GALLO Institute of Human Virology University of Maryland Biotechnology Institute 725 W Lombard Street Baltimore MD 21201 USA Institute of Infectious Diseases Emilio Ribas Sao Paulo 01246 Brazil Clinical Research Unit in Human Retrovirology University of CampinasSao Paulo 01246 Brazil. Institute of Infectious Diseases Emilio Ribas Sao Paulo 01246 Brazil

Neurological complications associated with HIV-1/AIDS are being recognized with a high frequency that parallels the increased number of AIDS cases. The early infiltration by HIV-1 into the nervous system can cause primary and/or secondary neurological complications. The most common neurocognitive disorder is AIDS Dementia Complex (ADC). In developing countries of Asia the three most opportunistic infections are tuberculosis (TB), cryptococcosis, and Pneumocystis carinii pneumonia. Therefore, it is expected that secondary neurological complications due to TB and cryptococcosis will be the most common cause of morbility and mortality in HIV-1/AIDS cases in China. Research of NeuroAIDS in China is necessary to understand the impact and the biology of HIV-1 in the nervous system. Future studies would include, the molecular epidemiology and the description of opportunistic infections associated to HIV-1; the neuropathological description of primary and secondary HIV-1 complications in different groups; the HIV-1 neurot- ropism and immune response studies for China’s unique HIV-1 strains and recombinant forms derived from the nervous system, including experimental models such as the use of transgenic rats; and the study of potential resistant virus, primarily when the anti-retroviral therapy (ART) has not full access in the brain.

关键词： NeuroAIDS HIV-1 neurotropism AIDS dementia complex.

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Inhaler Technique Questionnaire(InTeQ)in pediatric patients with asthma

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World Journal of Pediatrics 2023年第8期19卷 798-804页

作者： Catalina Lizano‑Barrantes Olatz Garin Alexandra Lelia Dima Karina Mayoral Angels Pont Eva María Ortiz María Araceli Caballero‑Rabasco Manuel Praena‑Crespo Laura Valdesoiro‑Navarrete María Teresa Guerra Alberto Bercedo‑Sanz Gimena Hernández Camila Maroni Inés de Mir MaríaÁngeles Carrasco marta ortega Alberto Servan JoséAntonio Castillo Eva Tato Montse Ferrer Health Services Research Group IMIM(Hospital del Mar Medical Research Institute)Barcelona Biomedical Research ParkDoctor Aiguader8808003 BarcelonaSpain Department of Medicine and Life Sciences Universitat Pompeu FabraBarcelonaSpain Department of Pharmaceutical Care and Clinical Pharmacy Faculty of PharmacyUniversidad de Costa RicaSan JoseCosta Rica Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública CIBERESP MadridSpain Research and Development Unit Institut de Recerca Sant Joan de DéuBarcelonaSpain Department of Pediatrics Obstetrics and Gynaecology and Preventive MedicineUniversitat Autònoma de BarcelonaBarcelonaSpain Pediatric Allergy and Pulmonology Unit Pediatric ServiceHospital del MarBarcelonaSpain Pediatric Allergy and Pulmonology Unit Pediatric ServiceHospital Universitari Parc TaulíSabadellSpain Centro de Salud La Candelaria Servicio Andaluz de SaludSevilleSpain Grupo de Vías Respiratorias de La Asociación Española de Pediatras de Atención Primaria(AEPAP) MadridSpain Centro de Salud Jerez Sur Servicio Andaluz de SaludSevilleSpain Centro de Salud La Sagrera BarcelonaSpain Centro de Salud Los Castros CantabriaSpain Facultat de Medicina Universitat Autònoma de BarcelonaBarcelonaSpain Pediatric Allergy and Pulmonology and Cystic Fibrosis UnitHospital Universitari Vall d’HebronBarcelonaSpain Consultorio Sevilla la Nueva MadridSpain Centro de Salud Dos de Mayo MadridSpain Hospital Miguel Servet ZaragozaSpain Hospital Universitario Araba Vitoria-GasteizSpain Departamento de Farmacologia Pediatría y RadiologíaUniversidad de SevillaSevilleSpain Institut d’Investigaciói InnovacióParc Taulí SabadellSpain

Asthma in school-aged children is a major public health problem worldwide[1,2].Inhaled medications are the mainstay of its pharmacological management[2],but only 8%-22%of children with asthma use their inhalers correc... 详细信息

关键词： asthma pediatric patients

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Differential response of injured and healthy retinas to syngeneic and allogeneic transplantation of a clonal cell line of immortalized olfactory ensheathing glia:a double-edged sword

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Neural Regeneration Research 2025年第8期20卷 2395-2407页

作者： María Norte-Muñoz María Portela-Lomba Paloma Sobrado-Calvo Diana Simón Johnny Di Pierdomenico Alejandro Gallego-ortega Mar Pérez JoséMCabrera-Maqueda Javier Sierra Manuel Vidal-Sanz María Teresa Moreno-Flores marta Agudo-Barriuso Grupo de Investigación Oftalmología Experimental Departamento de OftalmologíaOptometríaOtorrinolaringología y Anatomía PatológicaFacultad de MedicinaUniversidad de MurciaInstituto Murciano de Investigación Biosanitaria(IMIB)Campus de Ciencias de la SaludMurciaSpain Experimental Sciences Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain Anatomy Histology and Neuroscience DepartmentMedicine FacultyUniversidad Autónoma de MadridMadridSpain Center of Neuroimmunology Service of NeurologyLaboratory of Advanced Imaging in Neuroimmunological DiseasesHospital Clínic of BarcelonaInstitut d’Investigacions Biomèdiques August Pi i Sunyer(IDIBAPS)and Universitat de BarcelonaBarcelonaSpain Medicine Faculty Universidad Francisco de VitoriaPozuelo de AlarcónMadridSpain

Olfactory ensheathing glia promote axonal regeneration in the mammalian central nervous system,including retinal ganglion cell axonal growth through the injured optic ***,it is unknown whether olfactory ensheathing glia also have neuroprotective *** ensheathing glia express brain-derived neurotrophic factor,one of the best neuroprotectants for axotomized retinal ganglion ***,we aimed to investigate the neuroprotective capacity of olfactory ensheating glia after optic nerve *** ensheathing glia cells from an established rat immortalized clonal cell line,TEG3,were intravitreally injected in intact and axotomized retinas in syngeneic and allogeneic mode with or without microglial inhibition or immunosuppressive *** and gene expression analyses were *** bulb-derived primary olfactory ensheathing glia and TEG3 express major histocompatibility complex classⅡ*** and syngenically transplanted TEG3 cells survived in the vitreous for up to 21 days,forming an *** axotomized retinas,only the allogeneic TEG3 transplant rescued retinal ganglion cells at 7 days but not at 21 *** these retinas,microglial anatomical activation was higher than after optic nerve crush *** intact retinas,both transplants activated microglial cells and caused retinal ganglion cell death at 21 days,a loss that was higher after allotransplantation,triggered by pyroptosis and partially rescued by microglial inhibition or ***,neuroprotection of axotomized retinal ganglion cells did not improve with these *** different neuroprotective properties,different toxic effects,and different responses to microglial inhibitory treatments of olfactory ensheathing glia in the retina depending on the type of transplant highlight the importance of thorough preclinical studies to explore these variables.

关键词： cell therapy immune recognition major histocompatibility complex class II(MHCII) neuroprotection olfactory ensheathing glia retinal ganglion cells

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Technical aspects of uniportal VATS lung major resections with bronchovascular reconstruction

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中华胸部外科电子杂志 2021年第4期8卷 209-217页

作者： Julio Sesma Sergio Bolufer Carlos Galvez Francisco Lirio Juan JoséMafé Jone Miren Del Campo Sergio Maroto Leyre Sebastian marta ortega Luis Jorge Cerezal Department of Thoracic Surgery Hospital General Universitario AlicanteAlicanteSpain

Lung major resections involving bronchovascular reconstruction pose a surgical challenge due to their technical complexity and *** traditional techniques to perform vascular or bronchial reconstructions through multiportal video-assisted thoracoscopic surgery(VATS)approach can be applied also by uniportal VATS ***,specific tools have already been developed in order to facilitate these procedures through uniportal VATS approach increasing comfort and workspace through the single port *** procedures must be performed just in very highly uniportal VATS trained teams and it is recommended that teams who perform these techniques previously have completed the advanced learning curve for lung major resections through uniportal VATS *** aim of this paper is to describe the major key points for performing most frequent bronchovascular reconstructions through uniportal VATS approach in a safe and feasible *** technique is step by step described in order to safely perform most common uniportal VATS left/right side lung major bronchovascular resections and *** tip and tricks are detailed in order to facilitate vascular control,bronchovascular reconstructions and unexpected bleeding control through uniportal VATS approach.

关键词： Video-assisted thoracoscopic surgery(VATS) uniportal angioplasty bronchoplasty lung cancer sleeve bronchovascular reconstruction

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NHC-catalysed[3+2]-asymmetric annulation between pyrazolin-4,5-diones and enals:synthesis of novel spirocyclic pyrazolone γ-butyrolactones and computational study of mechanism and stereoselectivity

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Organic Chemistry Frontiers 2022年第2期9卷 420-427页

作者： marta Gil-Ordonez Alicia Maestro Pablo ortega Pablo G.Jambrina Jose M.Andres GIR-SintACat-Instituto Universitario CINQUIMA y Departamento de Química Orgánica Facultad de CienciasUniversidad de ValladolidPaseo Belén 747011 ValladolidSpain Departamento de Química Física University of Salamanca37008 SalamancaSpain

Chiral pyrazolones with a spirocyclic centre at the C4-position are widely found in a large family of medically relevant *** recent years,organocatalysis,particularly that performed with quiral N-heterocyclic carbenes(NHCs),has allowed the enantioselective synthesis of these spirocyclic compounds despite its inherent *** this work,we describe the fully diastereo-and highly enantioselective synthesis of novel spirocyclic pyrazolone γ-butyrolactones via NHC-catalysed[3+2]annulation reaction of enals and 1H-pyrazol-4,*** understand the catalytic mechanism and origin of stereoselectivity,electronic structure calculations were carried *** considering various pathways,we concluded that the stereoselectivity-determining step is the formation of the lactone that proceeds after addition of the NHC derived homoenolate to the electrophilic carbonyl group of pyrazolin-4,*** calculations predict that the free energy barrier is lower for the(RS)product,which is also the main product experimentally obtained.

关键词： synthesis spiro mechanism

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2022年欧洲血管外科学会(ESVS)下肢慢性静脉疾病管理临床实践指南(全译)

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中华血管外科杂志 2023年第1期8卷 76-158页

作者： Marianne G.De Maeseneer Stavros K.Kakkos Thomas Aherne Niels Baekgaard Stephen Black Lena Blomgren Athanasios Giannoukas Manjit Gohel Rick de Graaf Claudine Hamel-Desnos Arkadiusz Jawien Aleksandra Jaworucka-Kaczorowska Christopher R.Lattimer Giovanni Mosti Thomas Noppeney Marie JoseevanRijn Gerard Stansby 无 Philippe Kolh Frederico Bastos Gongalves Nabil Chakfé Raphael Coscas Gert J.deBorst Nuno V.Dias Robert J.Hinchliffe Igor B.Koncar Jes S.Lindholt Santi Trimarchi Rikka Tulamo Christopher P.Twine Frank Vermassen Anders Wanhainen Martin Bjorck Nicos Labropoulos Fedor Lurie Armando Mansilha Isaac K.Nyamekye marta Ramirez ortega Jorge H.Ulloa Tomasz Urbanek Andre M.van Rij Marc E.Vuylsteke 荷兰鹿特丹伊拉斯谟医疗中心皮肤科希腊帕特雷帕特雷大学血管外科爱尔兰科尔克大学医院和爱尔兰国立大学戈尔韦分校血管外科丹麦哥本哈根大学根措夫特医院和国家教学研究医院血管外科英国伦敦盖伊和圣托马斯医院及国王学院瑞典厄勒布罗大学医学院心血管和胸外科希腊塞萨利大学健康科学学院医学院拉里萨大学医院血管外科英国伦敦剑桥大学医院和帝国理工学院德国弗里德里希沙芬诊所诊断和介入放射科法国巴黎圣约瑟夫医院集团法国卡昂圣马丁私立医院血管内科波兰托伦市路德维克·赖德吉耶医学院尼古拉·哥白尼大学血管外科和血管学系波兰戈佐市静脉和美容医学中心、外科和妇科中心伦敦西北大学医疗保健NHS信托基金会英国伦敦帝国学院意大利卢卡Maria Domenica Barbantini诊所血管科纽伦堡MarthaMaria医院血管和血管内外科德国雷根斯堡大学医院血管和内皮外科荷兰鹿特丹伊拉斯谟医疗中心血管外科英国泰恩河畔纽卡斯尔弗里曼医院纽卡斯尔大学 ESVS Guidelines Committee 比利时利日利日大学生物医学和临床前科学系葡萄牙里斯本诺瓦德里斯本大学圣玛尔塔医院里斯本中心医院和诺瓦医学院法国斯特拉斯堡大学血管外科和肾移植系巴黎援助公社(AP-HP)CHU AmbroiseParé 法国布洛涅比兰科特巴黎萨克莱大学凡尔赛大学圣昆廷分校血管外科荷兰乌得勒支大学医学中心血管外科瑞典马尔默隆德大学斯科纳大学医院血管中心和马尔默临床科学英国布里斯托尔布里斯托尔大学塞尔维亚贝尔格莱德大学医学院塞尔维亚临床中心血管和血管内外科诊所丹麦欧登塞大学医院心胸血管外科意大利米兰大学临床与社区科学系米兰IRCCS CaGranda Ospedae Maggiore Policlinico基金会芬兰赫尔辛基赫尔辛基大学医院和赫尔辛基大学英国布里斯托尔北布里斯托尔NHS信托基金会布里斯托尔大学比利特根特大学医院瑞典乌普萨拉大学外科学系瑞典乌梅奥大学外科和围手术期科学系爱沙尼亚塔尔图塔尔图大学临床医学研究所外科学系美国纽约州石溪市石溪大学医学中心美国俄亥俄州托莱多普惠约布斯特血管研究所密歇根大学葡萄牙波尔图大学医学院英国伍斯特伍斯特郡皇家医院伍斯特郡急症医院NHS信托西班牙马德里La Luz Quiron Salud医院哥伦比亚波哥大安第斯大学圣菲基金会波兰卡托维兹西里西亚医科大学普通外科、血管外科、血管和静脉科新西兰达尼丁奥塔哥大学外科学系比利时Tielt圣安德列齐肯胡斯血管外科

2022年指南与2015年指南相比的新内容是什么?与2015年版《慢性静脉疾病(chronic venous disease,CVD)管理指南》1相比,该指南的总体结构做了很大修改,使其更加实用和方便。在不同章节中增加了关于管理策略的相关内容,并附有流程图。

关键词：临床实践指南血管外科学慢性静脉疾病管理指南流程图总体结构管理策略

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Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents

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Neural Regeneration Research 2024年第8期19卷 1835-1841页

作者： Irene Navarro-Lobato Mariam Masmudi-Martín Manuel F.López-Aranda Juan F.López-Téllez Gloria Delgado Pablo Granados-Durán Celia Gaona-Romero marta Carretero-Rey Sinforiano Posadas María E.Quiros-ortega Zafar U.Khan Laboratory of Neurobiology Centro de Investigaciones Médico Sanitarias(CIMES)University of MalagaMalagaSpain Department of Medicine Faculty of MedicineUniversity of MalagaMalagaSpain Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas(CIBERNED) Institute of Health Carlos IIIMadridSpain the Donders Institute for Brain Cognition and Behaviour Radboud UniversityNijmegenThe Netherlands the Brain Metastasis Group National Cancer Research Centre(CNIO)MadridSpain the Department of Neurobiology University of California-Los AngelesLos AngelesCAUSA

Memory deficit,which is often associated with aging and many psychiatric,neurological,and neurodegenerative diseases,has been a challenging issue for *** till now,all potential drug candidates have failed to produce satisfa ctory ***,in the search for a solution,we found that a treatment with the gene corresponding to the RGS14414protein in visual area V2,a brain area connected with brain circuits of the ventral stream and the medial temporal lobe,which is crucial for object recognition memory(ORM),can induce enhancement of *** this study,we demonstrated that the same treatment with RGS14414in visual area V2,which is relatively unaffected in neurodegenerative diseases such as Alzheimer s disease,produced longlasting enhancement of ORM in young animals and prevent ORM deficits in rodent models of aging and Alzheimer’s ***,we found that the prevention of memory deficits was mediated through the upregulation of neuronal arbo rization and spine density,as well as an increase in brain-derived neurotrophic factor(BDNF).A knockdown of BDNF gene in RGS14414-treated aging rats and Alzheimer s disease model mice caused complete loss in the upregulation of neuronal structural plasticity and in the prevention of ORM *** findings suggest that BDNF-mediated neuronal structural plasticity in area V2 is crucial in the prevention of memory deficits in RGS14414-treated rodent models of aging and Alzheimer’s ***,our findings of RGS14414gene-mediated activation of neuronal circuits in visual area V2 have therapeutic relevance in the treatment of memory deficits.

关键词： behavioral performance brain-derived neurotrophic factor cognitive dysfunction episodic memory memory circuit activation memory deficits memory enhancement object recognition memory prevention of memory loss regulator of G protein signaling

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The Role of Surgery in Primary Thyroid Lymphoma: Experience in the Last 10 Years of a Specialized Unit

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Journal of Cancer Therapy 2016年第13期7卷 1059-1070页

作者： Raquel Alfonso-Ballester María José Terol Castera Omar García Rodríguez Carolina Martínez Ciarpaglini marta Maia Boscá-Watts Norberto Cassinello Fernández Joaquín ortega Serrano Departments of Surgery (Endocrine Section) University Clinic Hospital of Valencia Valencia Spain Departments of Medical Oncology University Clinic Hospital of Valencia Valencia Spain Departments of Oral and Maxillofacial Surgery University Clinic Hospital of Valencia Valencia Spain Departments of Pathology University Clinic Hospital of Valencia Valencia Spain Departments of Digestive Medicine University Clinic Hospital of Valencia Valencia Spain

Primary Thyroid Lymphoma (PTL) is an uncommon disease, although its incidence is of 5%. Ultrasound and Fine Needle Aspiration Cytology (FNAC) usually do not provide the diagnosis. Surgery is one of the treatment options because it enables histological diagnosis and can also relieve compression symptoms in patients with rapid growth cervical mass. We present 7 cases of PTL diagnosed in the last 10 years in our unit. Five were female (71.4%) and 2 were male (28.6%). The mean age was 64.2 (range: 40 - 81);4 patients (57.1%) had associated Hashimoto’s Thyroiditis (HT). One patient (14.2%) had concomitant Graves disease. 5 cases presented with compressive symptoms and cervical mass. Ultrasound was not diagnostic in any case. FNAC was diagnostic only in one patient (14.3%). Five patients underwent total thyroidectomy (71.4%). All the cases were diagnosed with lymphoma postoperatively. Two interventions consisted of left hemithyroidectomies (28.6%). No complications appeared. 5 patients (71.4%) were classified as Mucosa-Associated Lymphoid Tissue (MALT) lymphoma. We also observed 1 Follicular grade I lymphoma and 1 Burkitt case. When the extension study was done, 1 patient was at stage IIIE (14%), 2 at IIE (28.5%) and 4 at IE (57.14%). Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP) and Iphosphamide, ethoposide and high dose Cytarabine (IVAC) were the treatment scheme when chemotherapy was used (in three cases). Two cases were treated only with total thyroidectomy, and 2 with total thyroidectomy and rituximab, and the latter was MALT. Complete Remission (CR) was achieved in all patients in the first year. All are still alive and in CR. In our experience, PTL diagnose can be challenging before surgery. Although surgery is not the gold standard for treatment, when it is done, it should be curative in MALT lymphomas confined to the thyroid.

关键词： Thyroid Lymphoma Thyroidectomy Endocrine Surgery Extranodal Lymphoma Malt Lymphoma Rituximab

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