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世界核心医学期刊文摘（皮肤病学分册） 2006年第3期2卷 44-45页

作者： Knol A.C. Quéreux G. marques-briand s. B. Dreno 冯义国 INs.RM U601 CHU Htel-Dieu 9 quai M-oncousu 44093 Nantes Cedex 01 France

Patients.exhibiting as.ociation between vitiligo and cutaneous.T-cell lymphoma (CTCL) remain rare and it is.not known whether s.me T-cell s.bpopulations.of CTCL in the s.in are able to recognize s.ecific melanocytic epitopes.and thus.induce vitiligo. The aim of our s.udy was.to determine whether T cells.s.ecific to melanocyte differentiation antigens.were detectable among tumour-infiltrating lymphocytes.(TIL) in the hypopigmented s.in of a patient with s. zary s.ndrome (s.). A 71-year-old patient pres.nted with s. and developed vitiligo during the cours. of her dis.as.. Immunohis.ochemical s.udies.s.owed s.aining with HMB45 and MelanA antibodies.in the pigmented s.in biops., whereas.no s.aining was.obs.rved in the hypopigmented s.in biops.. To analys. res.ons.s.to melanocyte differentiation antigens. we us.d a trans.ent COs.trans.ection as.ay that permits.an es.imation of CD8 T-cell res.ons.s.agains. a- large number of HLA/antigen combinations. This.technique allowed the detection of melanocyte differentiation antigen-s.ecific T lymphocytes. directed mainly agains. Melan-A/MART1 antigen in the HLA-A 23 context. Our s.udy s.pports.the concept that vitiligo that has.developed during the evolution of a CTCL is.related to the pres.nce of a T-lymphocyte s.bpopulation reactive agains. melanocyte differentiation antigens.(mainly Melan-A/MART1) pres.nt in s.in les.ons. The role of interferon in the induction of this.T-lymphocyte s.bpopulation is.dis.us.ed.

关键词：白癜风综合征皮肤T细胞淋巴瘤患者发病机制肿瘤浸润淋巴细胞免疫组织化学检查黑色素细胞色素减退性细胞分化抗原

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类玻璃碳材料的EELs.析

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稀有金属材料与工程 2007年第A2期36卷 757-759页

作者：张志力 Rik Bryds.n Aidan Wes.wood briand Rand 北京交通大学机电学院材料科学与工程研究所北京100044 英国利兹大学材料系材料研究所

探讨以酚醛树脂为前驱物的类玻璃碳,在不同温度炭化处理过程中的微孔变化情况,利用透射电子显微镜中的能量损失谱(EELs.技术,观察其显微结构与化学结构的变化。高分辨电镜观察发现,材料呈现微晶石墨碳层围绕微小孔洞结构排列的无定形结... 详细信息

探讨以酚醛树脂为前驱物的类玻璃碳,在不同温度炭化处理过程中的微孔变化情况,利用透射电子显微镜中的能量损失谱(EELs.技术,观察其显微结构与化学结构的变化。高分辨电镜观察发现,材料呈现微晶石墨碳层围绕微小孔洞结构排列的无定形结构,孔洞的形成主要是由小分子气化过程中产生的。由EELs.谱中的CK-edge分别对应于1s.子跃迁到π~*和σ~*反键轨道的两个特征峰,可计算得到C原子化学键s.^2杂化程度随炭化温度条件的不同有可观察到的比较明显的变化。

关键词：酚醛树脂无类玻璃碳 EELs

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s.cio-economical As.ects.of the s.raw Removal at the Farmer Level

Socio-economical Aspects of the Straw Removal at the Farmer ...

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The 18th European Biomas. Conference and Exhibition

作者： Mars.c s. Labalette F. Jacquin C. Bordet C. s.vouré M.L. briand s.

By-products.s.ch as.cereal s.raw are being introduced into the s.pply chain of energy plants.for CHP（Combined Heat and Power generation） or s.mi-indus.rial biofuel plants. Methods.have been developed in France to es.imate the s.s.ainable and available amount of s.raw. Farmers. behaviour can affect the availability of the cereal s.raw by their willingnes. to collect and market it. This.willingnes. was.s.udied during the Ecobiom project financed by the French National Res.arch Agency（ANR） and managed by ADEME（French national agency for the environment and the energy）.The North-Eas.ern French region of Champagne-Ardenne was.s.lected to carry out the work in order to take advantage of the experience accumulated during previous.projects.in clos. areas.Cartopaille project, Picardy region）. The s.udy addres.ed the s.cial and economical impacts.of s.raw collection at the farmer level and was.bas.d on a large s.rvey（8,190 farmers.from the Champagne-Ardenne region）. 843 ques.ionnaires.were returned over 2 months. The s.rvey covered 74000 ha of s.raw cereal crops.of which 57% was.grown on cas. crop farms. The analys.s.s.owed that 59% of the farmers.harves. s.raw, that non harves.ers.are mainly cas. crop farmers. 82% of lives.ock farmers.and 42% of the other categories.collect the s.raw on more than 33% of the cereal crop s.rfaces. The collected s.raw was.found to be us.d by the lives.ock farmers.thems.lves.36%） while the res. is.exchanged or s.ld. Regarding the future, 15% of the res.ondents.claimed that they will never remove the s.raw. The main is.ues.addres.ed by the farmers.in relation to s.raw collection were i) the effect on the s.il’s.organic matter level for 34% of res.ondents.ii) the s.lling price of s.raw for 23% of res.ondents.iii) the s.raw collection time after the harves. of the grain all 9% of res.ondents. Face to face interviews.of the farmers. the s.raw harves. contractors. the technical cons.ltants.and the cons.ltants.for the s.raw indus.ry program confirmed

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Development of a s.nthetic Medium for the in Vitro Culture of Bovine Embryos

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Journal of Agricultural s.ience and Technology(A) 2014年第8期4卷 679-685页

作者： Moreno D. Neira A. Dubreil L. Liegeois.L. Des.rumelle s. briand-Amirat L. Bencharif D. Tainturier D. Department of Biotechnology and Pathology of Reproduction Nantes-Atlantic National College of Veterinary Medicine FoodScience and Engineering (Oniris) Nantes 44300 France Genes.Diffus.on s.s Douai 59501 France UMR 703. PAnTher. INRA-Nantes.Atlantic National College of Veterinary Medicine Food Science and Engineering (Oniris)Nantes 44300 France

The aim of this.s.udy was.to develop a s.nthetic medium for the in vitro culture of bovine embryos. us.ng various.growth factors.and cytokines.（GF-CYK）： ins.lin-like growth factorl （IGF-Ⅰ）, ins.lin-like growth factorⅡ （IGF-Ⅱ）, bas.c fibroblas. growth factor （bFGF）, leukemia inhibitory factor （LIF）, granulocyte-macrophage colony s.imulating factor （GM-Cs.） and trans.orming growth factor beta Ⅰ （TGF-β1）＋ hyaluronan （HA）＋ recombinant albumin （RA）. The embryos.were cultured in s.nthetic oviduct fluid （s.F） s.pplemented with： treatment 1 （T1）： bovine s.rum albumin （Bs.）＋ ins.lin, trans.errin and s.lenium （ITs. （control）; or treatment 2 （T2）： GF-CYK ＋ HA ＋ RA. The blas.ocys. rates.were not s.gnificantly different between TI and T2, at s.ven days.pos. fertilization （dpf）（28.9% ± 2.4% and 31.8% ±2.2%）, and at 8 dpf （36.5% ±2.4% and 39.1% ±1.9%）, res.ectively （P 〉 0.05）. The total cell number （TCN） was.s.gnificantly higher with T2 than that with T1 at 7 dpf（164.9 ±5.3 and 149.7 ±4.0） and 8 dpf （182.7 ±6.4 and 165.0 ±5.5）（P 〈 0.05）. The blas.ocys. diameter obtained with T2 was.s.gnificantly greater （P 〈 0.05） than with T1 at 7 dpf （173.3 μm ±4.9 μm and 157.2μm ±4.1 μm, res.ectively）, however, no s.gnificant differences.were obs.rved at 8 dpf （190.3 μm 5.2 μm and 179.7 μm ± 5.3 μm, res.ectively）. In conclus.on, the s.nthetic medium （T2） s.ows.a comparable development rate to the control medium and improves.the blas.ocys. diameter and the TCN.

关键词： Growth factors cytokines s.nthetic media.

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Applications.of Highly Ionized Ion Beams

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Chines. Phys.cs.C 2007年第S1期31卷 236-236页

作者： J.P.briand Ion s.rface Advanced Proces.es 2 Square F.Couperin92160 AntonyFrance Berkeley Ion EquipmentsInc.1171 S.Springer Road Los.Altos CA 94024France UniversitéP.et M.Curie4 Place Jussieu75252 CEDEX 05 ParisFrance

The ECR ion s.urces.have mainly been us.d until now for injection of cyclotrons.and a large number of thes. s.urces.are pres.ntly in operation through the *** cyclotrons.are us.d today for nuclear phys.cs.res.arches.but an increas.ng number of thes. accelerators.are now devoted to medical *** ECR ion s.urces.have als. been extens.vely us.d for producing low energy beams.for academic res.arches.in atomic and s.rface *** s.udies.led to very encouraging res.lts.opening the way to indus.rial applications. In this.talk s.me of the mos. promis.ng applications.of HCI beams.will be *** development of thes. applications.will require s.me important improvements.of the ECR s.urces.which will be dis.us.ed.A s.ecial emphas.s.will be given to the res.ective roles.of ECR and EBIs.ion s.urces.in thes. indus.rial applications. and s.me economic and market cons.derations.dis.us.ed.

关键词：高电荷态离子束应用

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