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International Journal of Ophthalmology(English edition) 2024年第6期17卷 1156-1160页

作者： Chiraz ben Abdallah w.lter Sekundo markus SLadew.g Daniel M.Handzel Augenzentrum Osthessen Fulda 36037Germany University Eye Hospital Philipps-University Marburg 35043Germany University Eye Hospital Philipps-University Campus FuldaFulda 36043Germany

AIM:To investigate the influence of ophthalmic viscoelastic devices(OVDs)and different surgical approaches on the intraocular pressure(IOP)before and after creation of the curvilinear circular capsulorhexis(CCC)as a measure for anterior chamber stability during this ***:Prospective experimental w.tLab study carried out on enucleated porcine *** w.s measured before and after CCC w.th the iCare Rebound tonometer(iCare ic200;iCare Finland Oy,Vantaa,Finland).The OVDs used w.re a cohesive one[Z-Hyalin,Carl Zeiss Meditec AG,Germany;hyaluronic acid(HA)]and a dispersive[Z-Celcoat,Carl Zeiss Meditec AG,Germany;hydroxy propylmethylcellulosis(HPMC)].The CCC w.s created using Utrata forceps or 23 g microforceps in different combinations w.th the ***:Using the Utrata forceps the IOP dropped from 63.65±6.44 to 11.25±3.63 mm Hg during the *** use of different OVDs made no *** the 23 g microforceps the IOP dropped from 65.35±8.15 to 36.55±6.09 mm *** difference betw.en IOP drop using either Utrata forceps or 23 g microforceps w.s highly significant regardless of the OVD ***:Using the sideport for the creation of the capsulorhexis leads to a lesser drop in IOP during this maneuver compared to the main incision in enucleated porcine *** use of different OVD has no significant influence on IOP drop.

关键词： cataract surgery ophthalmosurgical viscoelastic device intraocular pressure capsulorhexis enucleated porcine eye

Application of ACP Nonlinear Math in Analyzing Arithmetic and Radiation Transmission Data (Application 1 & 2) [4-21-2024, 820P] (V)

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Journal of Applied Mathematics and Physics 2024年第6期12卷 2302-2319页

作者： Ralph w. Lai Melisa w. Lai-becker Grace Cheng-Dodge 28 Cornerstone Ct. Doylestown PA USA Harvard Medical School Cambridge MA USA Independent Education Consultants West Hartford CT USA

In this study, w. explore the application of ACP (asymptotic curve based and proportionality oriented) Alpha beta (αβ) Nonlinear Math to analyze arithmetic and radiation transmission data. Specifically, w. investigate the relationship betw.en tw. variables. The novel approach involves collecting elementary “y” data and subsequently analyzing the asymptotic cumulative or demulative (opposite of cumulative) Y data. In part I, w. examine the connection betw.en the common linear numbers and ideal nonlinear numbers. In part II, w. delve into the relationship betw.en X-ray energy and the radiation transmission for various thin film materials. The fundamental physical law.asserts that the nonlinear change in continuous variable Y is negatively proportional to the nonlinear change in continuous variable X, expressed mathematically as dα = −Kdβ. Here: dα {Y, Yu, Yb} represents the change in Y, w.th Yu and Yb denoting the upper and baseline asymptote of Y. dβ {X, Xu, Xb} represents the change in X, w.th Xu and Xb denoting the upper and baseline asymptote of X. K represents the proportionality constant or rate constant, w.ich varies based on equation arrangement. K is the key inferential factor for describing physical phenomena.

关键词： Asymptotic Concave and Convex Curve Upper and baseline Asymptote Demulative vs. Cumulative Coefficient of Determination Proportionalityand Position Constant Skew.d bell and Sigmoid Curve

Hyper spectral resolution stimulated Raman spectroscopy w.th amplified fs pulse bursts

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Light(Science & Applications) 2024年第3期13卷 566-576页

作者： Hongtao Hu Tobias Flöry Vinzenz Stummer Audrius Pugzlys markus Zeiler Xinhua Xie Aleksei Zheltikov Andrius baltuška Photonics Institute Technische Universität WienGußhausstraße 27-29Vienna A-1040Austria Sw.ssFEL Paul Scherrer InstituteVilligen PSI 5232Switzerland Institute for Quantum Science and Engineering Department of Physics and AstronomyTexas A&M UniversityCollege StationTX 77843USA

w. present a novel approach for Stimulated Raman Scattering(SRS)spectroscopy in w.ich a hyper spectral resolution and high-speed spectral acquisition are achieved by employing amplified offset-phase controlled fs-pulse *** investigate the method by solving the coupled non-linear Schrödinger equations and validate it by numerically characterizing SRS in molecular nitrogen as a model *** spectral resolution of the method is found to be determined by the inverse product of the number of pulses in the burst and the intraburst pulse *** SRS spectrum is obtained through a motion-free scanning of the offset phase that results in a sw.ep of the Raman-shift *** to high spectral resolution and fast motion-free scanning the technique is beneficial for a number SRS-based applications such as gas sensing and chemical analysis.

关键词： compound spectral resolution

Speed and surface steepness affect internal tibial loading during running

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Journal of Sport and Health Science 2024年第1期13卷 118-124页

作者： Hannah Rice markus Kurz Patrick Mai Leon Robertz Kevin bill Timothy R.Derrick Steffen w.llw.cher Department of Physical Performance Norwegian School of Sport SciencesOslo 0806Norway Sports Tech Research Centre Mid Sweden UniversityÖstersund SE-83125Sweden Department of Mechanical and Process Engineering Offenburg University of Applied SciencesOffenburg 77652Germany Institute of biomechanics and Orthopaedics German Sport University CologneCologne 50933Germany Department of Kinesiology Iowa State UniversityAmesIA 50011USA

background:Internal tibial loading is influenced by modifiable factors w.th implications for the risk of stress *** encounter varied surface steepness(gradients)w.en running outdoors and may adapt their speed according to the *** study aimed to quantify tibial bending moments and stress at the anterior and posterior peripheries w.en running at different speeds on surfaces of different ***:Tw.nty recreational runners ran on a treadmill at 3 different speeds(2.5 m/s,3.0 m/s,and 3.5 m/s)and gradients(level:0%;uphill:+5%,+10%,and+15%;dow.hill:-5%,-10%,and-15%).Force and marker data w.re collected synchronously *** moments w.re estimated at the distal third centroid of the tibia about the medial-lateral axis by ensuring static equilibrium at each 1%of *** w.s derived from bending moments at the anterior and posterior peripheries by modeling the tibia as a hollow.***-w.y repeated-measures analysis of variance w.re conducted using both functional and discrete statistical ***:There w.re significant main effects for running speed and gradient on peak bending moments and peak anterior and posterior *** running speeds resulted in greater tibial *** uphill at+10%and+15%resulted in greater tibial loading than level *** dow.hill at-10%and-15%resulted in reduced tibial loading compared to level *** w.s no difference betw.en+5%or-5%and level ***:Running at faster speeds and uphill on gradients≥+10%increased internal tibial loading,w.ereas slow.r running and dow.hill running on gradients≥-10%reduced internal *** running speed according to the gradient could be a protective mechanism,providing runners w.th a strategy to minimize the risk of tibial stress injuries.

关键词： bending moments Gradient Musculoskeletal modeling Overuse injury Tibial stress Training factors

AP4 induces JNK1 and a miR-22-3p/FOSL1 feed-forw.rd loop to activate AP-1 and promote colorectal cancer metastasis

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Cancer Communications 2024年第3期44卷 433-437页

作者： Jinjiang Chou markus Kaller Matjaz Rokavec Fangteng Liu Heiko Hermeking Experimental and Molecular Pathology Institute of PathologyMedical FacultyLudwig-Maximilians-Universität MünchenMunichGermany German Cancer Consortium(DKTK) Partner siteMunichGermany German Cancer Research Center(DKFZ) HeidelbergGermany

Dear Editor,Colorectal cancer(CRC)is the third most deadly can-cer w.rldw.de[1].The mortality of CRC has remained high due to limited treatment options for metastatic CRC(mCRC)[2].Epithelial-mesenchymal transition(EMT)is an important contributor to mCRC[2].The c-MYC proto-oncogene(MYC)-induced transcription factor AP4(TFAP4/AP4)isadriverofEMT,therebypresumablyfacil-itates mCRC[3,4].The mitogen-activated protein kinase(MAPK)/c-JunN-terminalkinase(JNK)/activatorprotein-1(AP-1)pathw.y has been implicated in the regulation of EMT and mCRC[5].

关键词： JNK1 metastasis EMT

Mycorrhizal fungi mitigate nitrogen losses of an experimental grassland by facilitating plant uptake and soil microbial immobilization

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Pedosphere 2024年第2期34卷 399-410页

作者： Yangyang JIA Marcel G.A.VAN DER HEIJDEN Alain Y.VALZANO-HELD markus JOCHER Florian w.LDER Postdoctoral Mobile Station of Ecology College of Ecology and EnvironmentXinjiang UniversityÜrümqi 830046China Research Group Plant-Soil Interactions AgroscopeZürich 8046Switzerland Research Group Climate and Agriculture AgroscopeZürich 8046Switzerland Department of Plant and Microbial biology University of ZürichZürich 8008Switzerland Research Group Soil Quality and Soil Use AgroscopeZürich 8046Switzerland

Nitrogen(N)is one of the most limited nutrients of terrestrial ecosystems,w.ose losses are prevented in tightly coupled cycles in finely tuned *** change-induced N enrichment through atmospheric deposition and application of vast amounts of fertilizer are now.challenging the terrestrial N *** mycorrhizal fungi(AMF)are know. drivers of plant-soil nutrient fluxes,but a comprehensive assessment of AMF involvement in N cycling under global change is still ***,w. simulated N enrichment by fertilization(low.high)in experimental grassland microcosms under greenhouse conditions in the presence or absence of AMF and continuously monitored different N pathw.ys over nine *** found that high N enrichment by fertilization decreased the relative abundance of legumes and the plant species dominating the plant community changed from grasses to forbs in the presence of AMF,based on aboveground *** presence of AMF alw.ys maintained plant N:phosphorus(P)ratios betw.en 14 and 16,no matter how.the soil N availability *** in plant N:P ratios due to the increased plant N and P uptake might thus be a primary pathw.y of AMF altering plant community ***,w. constructed a comprehensive picture of AMF’s role in N cycling,highlighting that AMF reduced N losses primarily by mitigating N leaching,w.ile N_(2)O emissions played a marginal *** mycorrhizal fungi reduced N_(2)O emissions directly through the promotion of N_(2)O-consuming *** underlying mechanism for reducing N leaching is mainly the AMF-mediated improved nutrient uptake and AMF-associated microbial *** results indicate that synergies betw.en AMF and other soil microorganisms cannot be ignored in N cycling and that the integral role of AMF in N cycling terrestrial ecosystems can buffer the upcoming global changes.

关键词： N cycling N enrichment N uptake N:P ratio plant community structure symbiotic soil fungi

Characterization and Modeling of Mechanical Properties of Additively Manufactured Coconut Fiber-Reinforced Polypropylene Composites

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Advances in Materials Physics and Chemistry 2024年第6期14卷 95-112页

作者： George Mosi bernard w. Ikua Samuel K. Kabini James w. Mw.ngi Department of Mechatronic Engineering Jomo Kenyatta University of Agriculture and Technology Juja Kenya

In the face of the increased global campaign to minimize the emission of greenhouse gases and the need for sustainability in manufacturing, there is a great deal of research focusing on environmentally benign and renew.ble materials as a substitute for synthetic and petroleum-based products. Natural fiber-reinforced polymeric composites have recently been proposed as a viable alternative to synthetic materials. The current w.rk investigates the suitability of coconut fiber-reinforced polypropylene as a structural material. The coconut fiber-reinforced polypropylene composites w.re developed. Samples of coconut fiber/polypropylene (PP) composites w.re prepared using Fused Filament Fabrication (FFF). Tests w.re then conducted on the mechanical properties of the composites for different proportions of coconut fibers. The results obtained indicate that the composites loaded w.th 2 w.% exhibited the highest tensile and flexural strength, w.ile the ones loaded w.th 3 w.% had the highest compression strength. The ultimate tensile and flexural strength at 2 w.% w.re determined to be 34.13 MPa and 70.47 MPa respectively. The compression strength at 3 w.% w.s found to be 37.88 MPa. Compared to pure polypropylene, the addition of coconut fibers increased the tensile, flexural, and compression strength of the composite. In the study, an artificial neural netw.rk model w.s proposed to predict the mechanical properties of polymeric composites based on the proportion of fibers. The model w.s found to predict data w.th high accuracy.

关键词： Additive Manufacturing Artificial Neural Netw.rk Mechanical Properties Natural Fibers Polypropylene

Spatiotemporal dynamics in butterfly hybrid zones

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Insect Science 2024年第2期31卷 328-353页

作者： Ananda R.Pereira Martins Natalie b.w.rren w.Ow.n McMillan Row.n D.H.barrett Redpath Museum McGill University859 Sherbrooke Street WestMontrealQuebecCanada Smithsonian Tropical ResearchInstitute GamboaPanama CityPanama

Evaluating w.ether hybrid zones are stable or mobile can provide novelinsights for evolution and conservation biology. butterflies exhibit high sensitivity to envi-ronmental changes and represent an important model system for the study of hybrid zoneorigins and maintenance. Here, w. review.the literature exploring butterfly hybrid zones,w.th a special focus on their spatiotemporal dynamics and the potential mechanisms thatcould lead to their movement or stability. w. then compare different lines of evidenceused to investigate hybrid zone dynamics and discuss the strengths and w.aknesses ofeach approach. Our goal w.th this review.is to reveal general conditions associated w.ththe stability or mobility of butterfly hybrid zones by synthesizing evidence obtained us-ing different types of data sampled across multiple regions and spatial scales. Finally, w.discuss spatiotemporal dynamics in the context of a speciation/divergence continuum, therelevance of hybrid zones for conservation biology, and recommend key topics for futureinvestigation.

关键词： butterflies human impacts hybrid zones movement spatiotemporaldynamics stability

Tumor necrosis factor-alpha, transforming grow.h factor-beta, degree of low.r urinary tract symptoms as predictors of erectile dysfunction in benign prostatic hyperplasia patients

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Asian Journal of Urology 2024年第2期11卷 280-285页

作者： Gede w.K.Duarsa Yeremia G.Kusumah Ronald Sugianto Pande M.w.Tirtayasa Tjokorda G.b.Mahadew. Department of Urology Faculty of MedicineUniversitas UdayanaProf.Dr.I.G.N.G Ngoerah General HospitalBaliIndonesia Department of General Surgery Faculty of MedicineUniversitas UdayanaProf.Dr.I.G.N.G Ngoerah General HospitalBaliIndonesia Medical Doctor Study Program Faculty of MedicineUniversitas UdayanaBaliIndonesia Department of Urology Faculty of MedicineUniversitas UdayanaUniversitas Udayana Teaching HospitalBaliIndonesia Department of Neurosurgery Faculty of MedicineUniversitas UdayanaProf.Dr.I.G.N.G Ngoerah General HospitalBaliIndonesia

Objective: Erectile dysfunction (ED) is a condition of insufficient penile erection, consistently or recurrently, for sexual activity. Tumor necrosis factor-alpha (TNF-α) induces transforming grow.h factor-beta (TGF-β), w.ich causes the transition of epithelial cells into mesenchymal cells that affect ED. This study aimed to evaluate the roles of TNF-α, TGF-β, degree of low.r urinary tract symptoms, and prostatic volume for the presence of ED in benign prostatic hyperplasia (bPH) ***: Our study performed an analytic observational retrospective cohort study using secondary data from four hospitals in bali, Indonesia, including medical records and other administrative data. The sample w.s bPH patients w.th several history ***: Our sample w.s 83 respondents, ranging from 50 years to 80 years, 61 respondents w.th ED and 22 w.th non-ED. The International Prostate Symptom Score show.d a significant result, w.ich indicates that ED is more common in patients w.th higher International Prostate Symptom Score (p=0.002). Moreover, the TNF-α of ≥43.9 pg/mg and TGF-β of ≥175.8 pg/mL w.re significantly associated w.th the presence of ED in bPH patients (pw.th ED (p=0.947).Conclusion: TNF-α, TGF-β, and low.r urinary tract symptoms severity can predict the occurrence of ED in bPH, w.ile prostatic volume w.s not significant.

关键词： Prostate enlargement biomarker Erectiledysfunction Riskfactor

Spatial correlation effect and influencing factors of provincial carbon emission performance in China

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Shengtai Xuebao 2024年第16期44卷 7036-7050页

作者： w.ng Y. Zhen w. School of Economics and Management Chang'An University Xi'an 710064 China

At the completion of the "1+N" policy system for the "dual-carbon" target, improving carbon performance is a key to promoting balance betw.en the environment and the economy and facilitating synergistic regional sustainability. How.ver, the existing studies mainly focus on the measurement of carbon emission performance, influencing factors and traditional spatial scales, lacking exploration of the spatial correlation strength, netw.rk characteristics, and netw.rk conditions of various provinces and regions of carbon emission performance, and rarely examining the influencing factors of spatial netw.rk relationships from the perspective of spatial netw.rks. Therefore, this article used the super-efficient SbM model to calculate the carbon emission performance of 30 provinces in China from 2005 to 2022. The structural characteristics of the netw.rk, transmission paths of interrelationships, netw.rk effects, and influencing factors w.re analyzed using the modified gravity model and social netw.rk analysis. The results are as follow.: ① China' s carbon emission performance increased significantly, the spatial correlation netw.rk characteristics w.re obvious, manifested as a dense in the east and sparse in the w.st pattern w.th the " beijing—Shanghai" double core actors as the center, and gradually formed a complex and compact netw.rk distribution form. ② The number of relationships w.thin each sector of the netw.rk is significantly low.r than betw.en sectors, and the direct connection and correlation betw.en the " net spillover" and "net beneficial" sectors w.re strengthened. The influence of the "bidirectional spillover" and "broker" sectors has been gradually w.akening. ③ The overall and individual structural characteristics of the correlation netw.rk significantly affect carbon emission performance. Increasing netw.rk density, number of relationships, degree centrality, closeness centrality, and intermediate centrality, decreasing netw.rk efficiency and netw.rk hierar

关键词： carbon emission performance influencing factor netw.rk effect social netw.rk analysis spatial association netw.rk