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作者： Antonio Meštrović marko Kumric Josko Bozic Department of Gastroenterology University Hospital of SplitSplit 21000Croatia Department of Pathophysiology University of Split School of MedicineSplit 21000Croatia

The timely introduction and adjustment of the appropriate drug in accordance with previously well-defined treatment goals is the foundation of the approach in the treatment of inflammatory bowel disease(IBD).The therapeutic approach is still evolving in terms of the mechanism of action but also in terms of the possibility of maintaining *** patients with achieved long-term remission,the question of de-escalation or discontinuation of therapy arises,considering the possible side effects and economic burden of long-term *** each of the drugs used in IBD(5-aminosalycaltes,immunomodulators,biological drugs,small molecules)there is a risk of ***,studies show that more than 50%of patients who discontinue therapy will *** on the findings of large studies and meta-analysis,relapse of disease can be expected in about half of the patients after therapy withdrawal,in case of monotherapy with aminosalicylates,immunomodulators or biological ***,longer relapse-free periods are recorded with withdrawal of medication in patients who had previously been on combination therapies immunomodulators and anti-tumor necrosis *** needs to be stressed that randomised clinical trials regarding withdrawal from medications are still *** making a decision on discontinuation of therapy,it is important to distinguish potential candidates and predictive factors for the possibility of disease *** calprotectin level has currently been identified as the strongest predictive factor for *** other predictive factors have also been identified,such as:High Crohn's disease activity index or Harvey Bradshaw index,younger age(40 years),smoking,young age of disease onset,steroid use 6-12 months before *** important factor in the decision to withdraw medication is the success of re-treatment with the same or other *** decision to discontinue therapy must be based on in

关键词： Inflammatory bowel disease Therapy discontinuation Therapy de-escalation Ulcerative colitis Crohn’s disease

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萨格勒布舞蹈中心

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城市环境设计 2010年第Z1期 252-255页

作者： Saa Begovi marko dabrovi Tatjana Grozdani Begovi Silvije Novak Jasminka Jug Zorislav Petri Zeljko Mohorovi Dijana Vandekar Marin Mikeli 3LHD

关键词：萨格勒布克罗地亚 LHD

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里耶卡庆典中心

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城市环境设计 2010年第Z1期 217-223页

作者： Saa Begovi marko dabrovi Tatjana Grozdani Begovi Silvije Novak Paula Kukuljica Zvonimir Mari Leon Lazaneo Eugen Popovi Nives Krsnik Rister Andrea Vukoji Domagoj Blazevi 3LHD

关键词：里耶卡 LHD 体育馆平面图图(数学)

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克罗地亚Lone酒店

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设计家 2012年第1期 74-79页

作者： Silvije Novak Tatjana Grozdani Begovi marko dabrovi Sasa Begovi Ljiljana Dordevi Ines Vlahovi Zeljko Mohorovi Kruno-slav Szorsen Nives Krsnik Rister Dijana Vandekar Tomislav Soldo Ana Deg Pauline Pan 3LHD Architects Numen/For Use

内设有248间客房的Lone酒店隶属于Maistra有限公司．外型被设计成极简风格的Y形；酒店周围环绕着高耸的古树，远远看去，它仿佛是一艘漂浮在半山腰处的巨型远洋轮船。尽管一眼看上去．Lone酒店并不醒目、别致，但这个区域内独特的自然... 详细信息

内设有248间客房的Lone酒店隶属于Maistra有限公司．外型被设计成极简风格的Y形；酒店周围环绕着高耸的古树，远远看去，它仿佛是一艘漂浮在半山腰处的巨型远洋轮船。尽管一眼看上去．Lone酒店并不醒目、别致，但这个区域内独特的自然景观对于更好地诠释酒店的整体设计理念十分有利。

关键词：酒店克罗地亚设计理念极简风格自然景观客房高耸

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Design and initial testing of a maize cob collection system

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International Journal of Agricultural and Biological Engineering 2024年第3期17卷 108-114页

作者： Bojan Dolšak Anita Breznik Klemen Kaučič Nataša Imenšek marko Marčec Peter Gselman Jani Humar Mitja Krajnc University of Maribor Faculty of Mechanical EngineeringSmetanova ulica 172000 MariborSlovenia ŽIPO Lenart Ltd. Šetarova 212230 LenartSlovenia KGS Krajnc Ltd Vinička vas 42230 LenartSlovenia Interkorn Ltd. Gančani 949231 BeltinciSlovenia

Maize cobs are valuable plant residues that can be used for many different purposes,including as a renewable energy *** their value,maize cobs are still underutilized,mainly because people are not aware of their potential and harvesting techniques for their collection are still being ***,this research focused on finding the most suitable energy-and time-efficient method for mechanical collection of maize *** the combine harvester with an additional hopper proved to be the most promising solution,as it allows harvesting and storage of maize grain and maize cobs in one pass,while the harvesting time remains almost the same and the maize cobs are of good quality,as they do not fall on the field.A prototype with enlarged openings in the straw walkers,an additional grab container for maize cobs,a transport auger,a transport cleaning fan with built-in knives,a transport tube and some other assemblies was fabricated and used in *** first test results are very encouraging(94.4%-96.0%purity of maize cobs)and the system has been patented as a promising solution,especially in times when the environmental sustainability of the planet and energy independence are becoming increasingly important.

关键词： maize cobs utilization mechanical harvesting combine harvester upgrade

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