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Journal of Environmental Sciences 2022年第6期34卷 175-183页

作者： Jun Li Anran Ren Ed van der mark Gang Liu Key Laboratory of Drinking Water Science and Technology Research Centre for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China Dunea Water Company Plaza of the United Nations 11-15Zoetermeer 2700 ATthe Netherlands Sanitary engineering Department of Water managementFaculty of Civil Engineering and GeosciencesDelft University of TechnologyDelft 2600 GAthe Netherlands

Drinking water quality deteriorates from treatment plant to customer taps, especially in the plumbing system. There is no direct evidence about what the differences are contributed by plumbing system. This study compared the water quality in the water main and at customer tap by preparing a sampling tap on the water main. The biomass was quantified by adenosine triphosphate(ATP) and the microbial community was profiled by 454 *** results showed that in distribution pipes, biofilm contributed >94% of the total biomass,while loose deposits showed little contribution(< 2%) because of the low amount of loose deposits. The distribution of biological stable water had minor effects on the microbiocidal water quality regarding both quantity(ATP 1 ng/L vs. 1.7 ng/L) and community of the bacteria. Whereas the plumbing system has significant contribution to the increase of active biomass(1.7 ng/L vs. 2.9 ng/L) and the changes of bacterial community. The relative abundance of Sphingomonas spp. at tap(22%) was higher than that at water main(2%), while the relative abundance of Pseudomonas spp. in tap water(15%) was lower than that in the water from street water main(29%). Though only one location was prepared and studied, the present study showed that the protocol of making sampling tap on water main offered directly evidences about the impacts of plumbing system on tap water quality, which makes it possible to distinguish and study the processes in distribution system and plumbing system separately.

关键词： Drinking water distribution system Plumbing system Microbiological water quality Sampling program 454 pyrosequencing

Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue

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World Journal of Gastroenterology 2017年第6期23卷 1018-1029页

作者： Sanne van Erp Ece Ercan Perla Breedveld Lianne Brakenhoff Eidrees Ghariq Sophie Schmid Matthias van Osch mark van Buchem Bart Emmer Jeroen van der Grond Ron Wolterbeek Daniel Hommes Herma Fidder Nic van der Wee Tom Huizinga Désirée van der Heijde Huub Middelkoop Itamar Ronen Andrea van der Meulen-de Jong Department of Gastroenterology and Hepatology Leiden University Medical Center C.J.Gorter Center Leiden University Medical Center Department of Radiology Leiden University Medical Center Department of Medical Statistics Leiden University Medical Center Center for Inflammatory Bowel Diseases University of California Los Angeles Department of Gastroenterology and Hepatology University Medical Center Utrecht Department of Psychiatry Leiden University Medical Center Department of Rheumatology Leiden University Medical Center Department of Neuropsychology Leiden University Medical Center Department of Radiology Leiden University Medical CenterLeiden

To evaluate brain involvement in quiescent Crohn’s disease (CD) patients with fatigue using quantitative magnetic resonance imaging (MRI).METHODSMultiple MRI techniques were used to assess cerebral changes in 20 quiescent CD patients with fatigue (defined with at least 6 points out of an 11-point numeric rating scale compared with 17 healthy age and gender matched controls without fatigue. Furthermore, mental status was assessed by cognitive functioning, based on the neuropsychological inventory including the different domains global cognitive functioning, memory and executive functioning and in addition mood and quality of life scores. Cognitive functioning and mood status were correlated with MRI findings in the both study *** glutamate + glutamine (Glx = Glu + Gln) concentrations (P = 0.02) and ratios to total creatine (P = 0.02) were found in CD patients compared with controls. Significant increased Cerebral Blood Flow (P = 0.05) was found in CD patients (53.08 ± 6.14 mL/100 g/min) compared with controls (47.60 ± 8.62 mL/100 g/min). CD patients encountered significantly more depressive symptoms (P 1-weighted analysis. In addition, no correlation was found between mental status and MRI *** work shows evidence for perfusion, neurochemical and mental differences in the brain of CD patients with fatigue compared with healthy controls.

关键词： Magnetic resonance imaging Systemic inflammation Fatigue Crohn’s disease Cognition

Why Languages Prefer Prohibitives

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外国语 2006年第1期29卷 2-25页

作者： Johan van der Auwera Center for Grammar Cognition and Typology University of Antwerp Belgium

This paper deals with prohibitive markers, i.e., negative markers that are more or less dedicated to the expression of a prohibition. It documents the variety in the formal make-up of these markers and it confirms the earlier claims that they are frequent everywhere, with at least one exception, viz., Western Europe. Four origins are discussed: prohibitive markers may derive from predicative constructions, they may appear as a side product of Jespersen’s cycle, they may derive from a univerbation of imperative and negative markers, and they may be borrowed. As explanation is offered as to why languages prefer to have prohibitive markers. It is argued that attempts to explain this preference in terms of morphosyntax are misguided. Instead a frequency-based semantic explanation is offered. The most frequent use of negatives are declarative, thereby inviting a static ‘it is not the case that’ paraphrase. It is important, however, to mark clearly that prohibitives are instances of a dynamic ‘let it be the case that’ appeal. The paper ends on a discussion of languages that do not employ prohibitive markers.

关键词：英语语法词义使用范围

Colour-ring wear and loss effects in citizen science mark-resighting studies

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Avian Research 2019年第2期10卷 148-162页

作者： Andrew M.Allen Bruno J.Ens Martijn van de Pol Henk van der Jeugd Magali Frauendorf Henk-Jan van der Kolk Kees Oosterbeek Jeroen Nienhuis Eelke Jongejans Department of Animal Ecology and Physiology Radboud University6500 GL NijmegenThe Netherlands Sovon Dutch Centre for Field Ornithology 6503 GANijmegen and Sovon-Texel1790 AB Den BurgThe Netherlands Department of Animal Ecology Netherlands Institute of Ecology NIOOKNAW6708 PB WageningenThe Netherlands Dutch Centre for Avian Migration and Demography 6700 AB WageningenThe Netherlands Centre for Avian Population Studies WageningenThe Netherlands

Background: Ring wear and loss may have important consequences for mark-recapture studies that aim to estimate survival trends. Our study quantifies the rates of wear and loss from a long-running colour-ringing project of the Eurasian Oystercatcher (Haematopus ostralegus) in the Netherlands. Methods: Our analysis included 8909 colour-ringed oystercatchers with 118,071 resightings, predominantly ringed and observed by citizen scientists. We quantified how ring wear and loss may vary with ring colour and age, and how this may impact resighting probabilities. We then determined how ring loss may impact survival estimates and resighting probabilities of mark-recapture models by simulating four scenarios of how citizen scientists may resight and report birds with lost colour rings. Results: Annual rates of colour ring loss averaged 2.5% compared with 1% for ring wear, but lost rings also had a higher reporting probability (31.2%) than worn rings (10.3%). Lost rings may not directly impact survival estimates since 50% of oystercatchers with lost rings could still be uniquely identified. Ring wear and loss rapidly increased between 10 and 15 years after ringing. Rates of ring loss were comparable amongst ring colours, but the wear rate appeared higher for red and white rings compared to other colours. Rates of ring wear and loss varied significantly amongst different regions in our study, which were characterised as having different habitat features. Differential rates of ring wear may have important implications for studies conducted over large geographical scales or of multiple species. Conclusions: Based on simulations of ring loss in our population, estimates of apparent survival may be 0.3–1.2% lower whilst the impact of ring wear was deemed even lower. We developed a table of recommendations containing advice for ring fitting, data collection, study design, and mark-recapture analyses, so that future colour-ringing studies can benefit from our experiences in collecti

关键词： Bias Bird migration Citizen science Colour-ring mark-recapture Shorebirds Survival

Prevalence of-and risk factors for work disability in Dutch patients with inflammatory bowel disease

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World Journal of Gastroenterology 2017年第46期23卷 8182-8192页

作者： Lieke M Spekhorst Bas Oldenburg Ad A van Bodegraven Dirk J de Jong Floris Imhann Andrea E van der Meulen-de Jong Marieke J Pierik Janneke C van der Woude Gerard Dijkstra Geert D'Haens mark Lowenberg Rinse K Weersma Eleonora AM Festen 无 Department of Gastroenterology and Hepatology University of Groningen and University Medical Centre Groningen Department of Genetics University of Groningen and University Medical Centre Groningen Department of Gastroenterology and Hepatology University Medical Center Utrecht Department of Gastroenterology and Hepatology VU University Medical Center Department of Gastroenterology and Hepatology University Medical Center St. Radboud Department of Gastroenterology and Hepatology Leiden University Medical Center Department of Gastroenterology and Hepatology University Medical Center Maastricht Department of Gastroenterology and Hepatology Erasmus Medical Center Department of Gastroenterology and Hepatology Amsterdam Medical Center Parelsnoer Institute and the Dutch Initiative on Crohn and Colitis

AIM To determine the prevalence of work disability in inflammatory bowel disease(IBD), and to assess risk factors associated with work *** For this retrospective cohort study, we retrieved clinical data from the Dutch IBD Biobank on July 2014, containing electronic patient records of 3388 IBD patients treated in the eight University Medical Centers in the Netherlands. Prevalence of work disability was assessed in 2794 IBD patients and compared with the general Dutch population. Multivariate analyses were performed for work disability(sick leave, partial and full disability) and long-term full work disability(> 80% work disability for > 2 years).RESULTS Prevalence of work disability was higher in Crohn's disease(CD)(29%) and ulcerative colitis(UC)(19%) patients compared to the general Dutch population(7%). In all IBD patients, female sex, a lower education level, and extra-intestinal manifestations, were associated with work disability. In CD patients, an age > 40 years at diagnosis, disease duration > 15 years,smoking, surgical interventions, and anti-TNFα use were associated with work disability. In UC patients, an age > 55 years, and immunomodulator use were associated with work disability. In CD patients, a lower education level(OR = 1.62, 95%CI: 1.02-2.58), and in UC patients, disease complications(OR = 3.39, 95%CI: 1.09-10.58) were associated with long-term full work *** The prevalence of work disability in IBD patients is higher than in the general Dutch population. Early assessment of risk factors for work disability is necessary, as work disability is substantial among IBD patients.

关键词： Inflammatory bowel disease Crohn’s disease Ulcerative colitis Work disability Health care costs

Towards Quantitatively Understanding the Complexity of Social-Ecological Systems——From Connection to Consilience

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International Journal of Disaster Risk Science 2017年第4期8卷 343-356页

作者： Xiao-Bing Hu Peijun Shi Ming Wang Tao Ye mark S.Leeson Sander E.van der Leeuw Jianguo Wu Ortwin Renn Carlo Jaeger State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal University Academy of Disaster Reduction and Emergency Management Beijing Normal University School of Engineering University of Warwick Key Laboratory of Environmental Change and Natural Disaster Ministry of Education Beijing Normal University ASU-SFI Center for Biosocial Complex Systems Arizona State University School of Life Sciences and School of Sustainability Arizona State University Stuttgart Research Center for Interdisciplinary Risk and Innovation Studies University of Stuttgart Global Climate Forum

The complexity of social-ecological systems(SES) is rooted in the outcomes of node activities connected by network topology. Thus far, in network dynamics research, the connectivity degree(CND), indicating how many nodes are connected to a given node, has been the dominant concept. However, connectivity focuses only on network topology, neglecting the crucial relation to node activities, and thereby leaving system outcomes largely unexplained. Inspired by the phenomenon of ‘‘consensus of wills and coordination of activities' ' often observed in disaster risk management, we propose a new concept of network characteristic, the consilience degree(CSD),aiming to measure the way in which network topology and node activities together contribute to system outcomes. The CSD captures the fact that nodes may assume different states that make their activities more or less *** two nodes with in/compatible states will lead to outcomes that are un/desirable from the perspective of the SES in question. We mathematically prove that the CSD is a generalized CND, and the CND is a special case of CSD. As a general, fundamental concept, the CSD can facilitate the development of a new framework of network properties, models, and theories that allows us to understand patterns of network behavior that cannot be explained in terms of connectivity alone. We further demonstrate that a co-evolutionary mechanism can naturally improve the CSD. Given the generality of co-evolution in SES, we argue that the CSD is an inherent attribute rather than an artificial concept, which underpins the fundamental importance of the CSD to the study of SES.

关键词： Complex networks Consilience degree Co-evolution Disaster risk reduction Social-ecological systems

INVESTIGATIONS ON VINYLENE CARBONATE Ⅰ. PREPARATION AND PROPERTIES OF POLY-(VINYLENEC ARBONATE)

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Chinese Journal of Polymer Science 1990年第3期8卷 197-203页

作者：黄家贤陈国华 EDDY TIJSMA LEEN van der DOES ADRIAAN BANTJES Nankai University Department of Chemistry Tianjin People's Republic of China Department of Chemical Technology Biomaterials Section Twente University P. O. Box 217 7500 AE Enschede The Netherlands

Bulk polymerization of vinylene carbonate using t-butylperoxypivalate at 40℃gave colourless, high molecular weight poly(vinylene carbonate) (PVCA). Solutions of PVCA in acetone and DMF are not stable at 25℃and this ... 详细信息

关键词： Vinylene carbonate Polymerization High Molecular Weight Degradation mark-Houwink Equation.

Exploration and Application of Ubiquitous Mapping in Engineering Practice Courses in the Intelligence Age

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Journal of Geodesy and Geoinformation Science 2022年第3期5卷 58-66页

作者： Wei LI Xukang XIE Haowen YAN van der Meijde mark Lulu LIU Qianwen WANG Pengcheng GAO Hongyuan YU Faculty of Geomatics Lanzhou Jiaotong UniversityLanzhouGansu 730070China National-Local Joint Engineering Research Center of Technologies and Applications for National Geographic State Monitoring LanzhouGansu 730070China Gansu Provincial Engineering Laboratory for National Geographic State Monitoring LanzhouGansu 730070China School of Civil Engineering Lanzhou Jiaotong UniversityLanzhou 730070China Faculty of Geo-Information Science and Earth Observation University of TwenteEnschede 7514 AEthe Netherlands Institute of Education Tsinghua UniversityBeijing 100084China School of Civil Engineering Hexi UniversityZhangye 734000China

In the current era of digital surveying and mapping to intelligent surveying and mapping,ubiquitous surveying and mapping has brought many opportunities and challenges to college engineering course *** the development of ubiquitous surveying and mapping,college engineering practice courses urgently need to respond to ubiquitous surveying and *** research aims to integrate the development of ubiquitous surveying and mapping into the teaching of engineering practice courses in colleges,including promoting Android,Brower/Server(B/S),and Client/Server(C/S)to build a platform for practice *** also incorporates real development cases in measurement data processing such as gravity field *** this way,the teaching level of engineering practice courses in colleges can be improved,and new ideas can be put forward for cultivating surveying and mapping talents in the new era in ***,it can also provide new ideas for the organization of surveying and mapping practice courses under the background of the pandemic.

关键词： intelligence age ubiquitous mapping engineering practice courses platform design pandemic

MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines

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World Journal of Gastroenterology 2014年第40期20卷 14904-14912页

作者： Richard Hummel Corina Sie David I Watson Tingting Wang Alfiya Ansar Michael Z Michael mark van der Hoek Joerg Haier Damian J Hussey Department of Surgery Flinders University Bedford Park South Australia 5042 Australia Department of General and Visceral Surgery University of Muenster 48149 Muenster Germany Department of Gastroenterology and Hepatology Flinders University 5042 Bedford Park South Australia Australia Adelaide Microarray Centre SA Pathology 5000 Adelaide South Australia Australia Comprehensive Cancer Centre University of Muenster 48149 Muenster Germany

AIM: To investigate expression of microRNA (miRNA) and potential targets in chemotherapy resistant esophageal cancer cell lines.

关键词： Esophageal cancer MicroRNA Chemotherapy Resistance Target