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An Improved Coupled Level Set and Continuous Moment-of-Fluid Method for Simulating Multiphase Flows with Phase Change

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1034-1069页

作者： Zhouteng Ye Cody Estebe Yang Liu Mehdi Vahab Zeyu Huang mark sussman Alireza Moradikazerouni Kourosh Shoele Yongsheng Lian Mitsuhiro Ohta M.Yousuff Hussaini ZJUI Institute Zhejiang UniversityHaining 314400ZhejiangChina Department of Mathematics Florida State UniversityTallahasseeUSA Department of Mechanical Engineering Florida State UniversityTallahasseeUSA Mechanical and Aerospace Engineering Mathworks NatickMAUSA School of Aerospace Engineering Tsinghua UniversityBeijing 100084China Department of Mechanical Engineering University of LouisvilleLouisvilleUSA Department of Mechanical Science Tokushima UniversityTokushimaJapan

An improved algorithm for computing multiphase flows is presented in which the multimaterial Moment-of-Fluid(MOF)algorithm for multiphase flows,initially described by Li et al.(2015),is enhanced addressing existing MOF difficulties in computing solutions to problems in which surface tension forces are crucial for understanding salient flow *** Continuous MOF(CMOF)method is motivated in this *** CMOF reconstruction method inherently removes the"checkerboard instability"that persists when using the MOF method on surface tension driven multiphase(multimaterial)*** CMOF reconstruction algorithm is accelerated by coupling the CMOF method to the level set method and coupling the CMOF method to a decision tree machine learning(ML)*** flow examples are shown in the two-dimensional(2D),three-dimensional(3D)axisymmetric"RZ",and 3D coordinate *** include two material and three material multiphase flows:bubble formation,the impingement of a liquid jet on a gas bubble in a cryogenic fuel tank,freezing,and liquid lens dynamics.

关键词： Moment-of-Fluid(MOF) Surface tension Two phase flow Phase change Deforming boundaries with change(s)in topology Two-dimensional(2D) Three-dimensional(3D)axisymmetric 3D

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Simulation of Liquid Metal Droplets from Field Emission

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Communications in Computational Physics 2007年第4期2卷 640-661页

作者： Anton VanderWyst Andrew Christlieb mark sussman Iain D.Boyd Raytheon Missile Systems 1151 E.Hermans RoadP.O.Box 11337TucsonAZ 85734USA Department of Mathematics Michigan State UniversityEast LansingMI 48824USA Department of Mathematics Florida State UniversityTallahasseeFL 32306USA Department of Aerospace Engineering University of MichiganAnn ArborMI 48109USA.

Liquid metal droplets are accelerated by electrostatic forces in a process known as field *** this study,we simulate the emission of charged indium droplets on a needle in 2D cylindrical *** boundary element method is used to rapidly and accurately calculate the electric field on the fluid surface,which is then advected forward in time using level *** is the first time these methods have been combined,and this combination addresses difficult detachable surface tracking issues successfully.A histogram of droplet charge-to-mass ratio is generated in which it is predicted that smaller satellite droplets are more densely *** addition,our model is compared with independent pre-and post-snap off data and produces good agreement with the result.

关键词： Field emission electric propulsion modeling level set boundary element method

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Therapeutic drug monitoring in patients with inflammatory bowel disease

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World Journal of Gastroenterology 2014年第13期20卷 3475-3484页

作者： Andres J Yarur Maria T Abreu Amar R Deshpande David H Kerman Daniel A sussman Division of Gastroenterology University of Miami Leonard Miller School of MedicineMiamiFL 33136United States

Thiopurine analogs and anti-tumor necrosis factor (TNF) agents have dramatically changed the therapeutics of inflammatory bowel diseases (IBD), improving short and long-term outcomes. Unfortunately some patients do not respond to therapy and others lose response over time. The pharmacokinetic properties of these drugs are complex, with high inter-patient variability. Thiopurine analogs are metabolized through a series of pathways, which vary according to the patients’ pharmacogenetic profile. This profile largely determines the ratios of metabolites, which are in turn associated with likelihoods of clinical efficacy and/or toxicity. Understanding these mechanisms allows for manipulation of drug dose, aiming to reduce the development of toxicity while improving the efficacy of treatment. The efficacy of anti-TNF drugs is influenced by many pharmacodynamic variables. Several factors may alter drug clearance, including the concomitant use of immunomodulators (thiopurine analogs and methotrexate), systemic inflammation, the presence of anti-drug antibodies, and body mass. The treatment of IBD has evolved with the understanding of the pharmacologic profiles of immunomodulating and TNF-inhibiting medications, with good evidence for improvement in patient outcomes observed when measuring metabolic pathway indices. The role of routine measurement of metabolite/drug levels and antibodies warrants further prospective studies as we enter the era of personalized IBD care.

关键词： Inflammatory bowel disease Anti-tumor necrosis factor Infliximab Adalimumab Drug level Azathioprine Thiopurines Antibodies Drug monitoring Thioguanine

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基于获益的针对性治疗可以提高降压治疗效果

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中华高血压杂志 2014年第1期22卷 85-86页

作者： sussman J 《中华高血压杂志》编辑部

对于高血压患者,目前大多数指南推荐目标治疗(TTT)方案。但除了血压外,其他心血管危险因素,如年龄、吸烟和血脂水平及药物的相对风险降低程度等都会影响患者的预后。sussman等提出了根据患者的预期绝对净获益情况来制定治疗方案,即基于... 详细信息

对于高血压患者,目前大多数指南推荐目标治疗(TTT)方案。但除了血压外,其他心血管危险因素,如年龄、吸烟和血脂水平及药物的相对风险降低程度等都会影响患者的预后。sussman等提出了根据患者的预期绝对净获益情况来制定治疗方案,即基于获益的针对性治疗(BTT)。通过比较这两种治疗方案对终点事件的影响,发现与TTT相比,BTT治疗5年可以阻止更多心血管事件发生及延长质量调整生命年(QALYs),提示BTT较目前多数指南推荐的TTT方案更能改善患者的预后。该研究对于探索我国高血压人群的管理有很好的参考价值。当然,该研究是针对美国人群进行的,BTT方案还需要更多的研究进行探讨。

关键词：治疗效果高血压患者心血管危险因素质量调整生命年降压治疗方案心血管事件高血压人群

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SARS-COV-2 infection(coronavirus disease 2019)for the gastrointestinal consultant

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World Journal of Gastroenterology 2020年第14期26卷 1546-1553页

作者： Kaveh Hajifathalian Srihari Mahadev Robert E Schwartz Shawn Shah Kartik Sampath Felice Schnoll-sussman Robert S Brown Jr David Carr-Locke David E Cohen Reem Z Sharaiha Division of Gastroenterology and Hepatology Weill Cornell MedicineNew York-Presbyterian HospitalNew YorkNY 10021United States

The current pandemic due to the severe acute respiratory syndrome coronavirus 2 has caused an extreme burden for health care systems globally,and the number of cases is expected to continue to increase,at least in the immediate *** virus is estimated to have infected more than 1.5 million *** available reports suggest that gastrointestinal(GI)involvement in coronavirus disease 2019(COVID-19)is common and in some cases the GI symptoms may precede the respiratory *** addition to direct effects of severe acute respiratory syndrome coronavirus 2,the infected patients remain at risk for the complications commonly managed by gastroenterology and hepatology *** most commonly reported GI manifestation of COVID-19 is diarrhea,which is reported in a third to up to more than half of the *** to moderate elevation of the liver enzymes are also common,although no case of acute liver failure has been reported so *** of the medications used for treatment of COVID-19 can also be associated with GI symptoms or liver injury and can be included in the differential diagnosis in these *** the diagnosis of the infection is currently based on RNA analysis in respiratory samples,the available literature on fecal shedding of this virus suggests that fecal RNA testing might prove to be a useful diagnostic *** is reasonable to delay all non-urgent endoscopic procedures during the peak of the pandemic and use additional protective equipment such as N95 respirators during endoscopy while most patients can be considered high risk for having been exposed to the virus.

关键词： SARS-CoV-2 COVID-19 Gastroenterology Hepatology Liver

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Is There Growth in Grief: Measuring Posttraumatic Growth in the Grief Response

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Open Journal of Medical Psychology 2012年第3期1卷 38-43页

作者： Joleen Schoulte Zachary sussman Benjamin Tallman Munni Deb Courtney Cornick Elizabeth Altmaier Department of Psychological and Quantitative Foundations University of Iowa Iowa City USA

Introduction: Grief is considered to be negative manifestations of affect, cognition, and behavior. However, persons who experience grief have also reported enduring positive outcomes in such domains as interpersonal relationships, personal strengths, and life perspectives. This review evaluated current measures of grief to determine if such positive outcomes can be adequately assessed. Methods: The Texas Revised Inventory of Grief, Grief Experience Inventory, Bereavement Phenomenology Questionnaire, Core Bereavement Items, Continuing Bonds Scale, and Hogan Grief Reaction Checklist (currently the most common measures of grief) are reviewed. Results: Only one of the reviewed measures assessed posttraumatic growth as a component of grief (i.e., Hogan Grief Reaction Checklist). Conclusion: Since posttraumatic growth and negative psychological adjustment after traumatic events can coexist, it is important that measures of grief used in both clinical and research domains allow an assessment of positive response.

关键词： Posttraumatic Growth Grief Bereavement Adjustment Assessment

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穿越十万年为地球生命史造像

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中国国家旅游 2015年第12期 62-67页

作者： molly Rachel sussman

2004年起，美国摄影师蕾切尔·萨斯曼（Rachelsussman）与生物学家一起周游世界，搜寻并拍摄在地球上持续生活了2000年乃至更长久的生物。如今她已经拍摄了将近20种不同类型的古老生命，包括灌木丛、西伯利亚真菌和长得像巨型大脑的圆... 详细信息

2004年起，美国摄影师蕾切尔·萨斯曼（Rachelsussman）与生物学家一起周游世界，搜寻并拍摄在地球上持续生活了2000年乃至更长久的生物。如今她已经拍摄了将近20种不同类型的古老生命，包括灌木丛、西伯利亚真菌和长得像巨型大脑的圆顶珊瑚。自然和人类千万年来的历史，就隐藏在这些生物体内，它们都是生命史的缩写。

关键词：生命史地球生物学家西伯利亚生物体内摄影师拍摄

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美国市政绿色建筑法令评析

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时代经贸 2011年第8期9卷 60-62页

作者： Marile sussman 张醒声（译）浙江大学光华法学院浙江杭州310008

美国的众多市政当局在过去的几年里纷纷出台了关于绿色建筑的法令条例。这些法令条例被编成目录，列于气候变化法律研究中心网站的市政绿色建筑法令电子表格之中，并接受审查。为了更好地理解在起草出台一个规范的绿色建筑法令过程中需... 详细信息

美国的众多市政当局在过去的几年里纷纷出台了关于绿色建筑的法令条例。这些法令条例被编成目录，列于气候变化法律研究中心网站的市政绿色建筑法令电子表格之中，并接受审查。为了更好地理解在起草出台一个规范的绿色建筑法令过程中需要作出的决定，本文主要讨论制定出列于电子表格中的法令的市政当局所做的不同选择，并备注了诸多市政当局中意见一致的地区。

关键词：绿色建筑法令市政美国电子表格法律研究气候变化起草

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应用于区域交通战略规划中的情景规划

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国外城市规划 2006年第6期21卷 101-111页

作者： Christopher Zegras Joseph sussman Christopher Conklin 高璟麻省理工学院城市研究与规划系东日本铁道公司 VHB公司同济大学建筑与城市规划学院城市规划系

本文简要回顾了情景规划从商业战略规划活动中产生后的历史,对其目标与局限性进行了综述。然后文章回顾了情景规划在区域交通规划中的应用背景和先例,介绍了情景规划在休新敦大都市区交通中应用和深化的工作框架,讨论了这一应用的主要... 详细信息

本文简要回顾了情景规划从商业战略规划活动中产生后的历史,对其目标与局限性进行了综述。然后文章回顾了情景规划在区域交通规划中的应用背景和先例,介绍了情景规划在休新敦大都市区交通中应用和深化的工作框架,讨论了这一应用的主要成果和教训,并时进一步的发展潜力和改进措施提出了作者的观察和结论。

关键词：大都市交通规划情景规划预测休斯敦德克萨斯

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世界上最老最老的生命

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作者： (美)蕾切尔·萨斯曼(Rachel sussman)

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