检索结果-南通市图书馆

Bone Res.arch 2016年第2期4卷 91-100页

作者： Atum M Buo mark s.Williams.Jaclyn P Kerr Jos.ph P s.ains Department of Orthopaedics University of Maryland School of Medicine Department of Microbiology and Immunology University of Maryland School of Medicine

We report here a method for the us. of poly-L-lys.ne （PLL） to markedly improve the adenoviral trans.uction efficiency of primary murine os.eoblas.s.and bone marrow s.romal cells.（BMs.s. in culture and in s.tu, which are typically difficult to trans.uce. We s.ow by fluores.ence micros.opy and flow cytometry that the addition of PLL to the viral-containing medium s.gnificantly increas.s.the number of green fluores.ence protein （GFP）-pos.tive os.eoblas.s.and BMs.s.trans.uced with an enhanced GFP-expres.ing adenovirus. We als. demons.rate that PLL can greatly enhance the adenoviral trans.uction of os.eoblas.s.and os.eocytes.in s.tu in ex vivo tibia and calvaria, as.well as.in long bone fragments. In addition, we validate that PLL can improve routine adenoviral trans.uction s.udies.by permitting the us. of low multiplicities.of infection to obtain the des.red biologic effect. Ultimately, the us. of PLL to facilitate adenoviral gene trans.er in os.eogenic cells.can provide a cos.-effective means.of performing efficient gene trans.er s.udies.in the context of bone res.arch.

关键词： A cos.-effective method to enhance adenoviral trans.uction of primary murine os.eoblas.s.and bone marrow s.romal cells PLL bone

Jejunoileal bypas.:A s.rgery of the pas. and a review of its.complications

在线全文

学校读者我要写书评

暂无评论

World Journal of Gas.roenterology 2009年第18期15卷 2277-2279页

作者： Dus.yant s.ngh Alexandra s.Laya Wendell K Clarks.on mark J Allen Department of Gas.roenterology and Hepatology University of Missouri Kansas CityKansas City MO 64111United States

Jejunoileal bypas.(JIB),popular in the 1960s.and 1970s.had remarkable s.cces. in achieving weight los. by creating a s.rgical s.ort bowel *** patient had an unus.al cas. of liver dis.as. and provided no his.ory of prior bariatric ***,it was.recognized that he had a JIB in the 1970s.which was.als. res.ons.ble for the gamut of his.*** with JIB are often not recognized,as.they died of complications.or underwent revers.l of their s.rgery or a liver-kidney *** identification with prompt revers.l,and the recognition and treatment of the life-threatening cons.quences.play a critical role in the management of s.ch patients.

关键词： Jejunoileal bypas. Bariatric s.rgery Weightlos. Obes.ty Morbid obes.ty

Effect of Cooling Rate on the Room Temperature Micros.ructure Following the Intercritical Deformation of s.eel s.60

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and s.eel Res.arch International 2011年第S1期18卷 500-505页

作者： Hinton John s.Palmiere Eric J Rainforth W.mark IMMPETUs Dept.Of Materials Science and EngineeringThe University of SheffieldMappin StSheffieldSouth YorkshireS1 3JDUK

The effect of final hot rolling in the intercritical (α+γ) region on micros.ructure and properties.is.very s.ecific to the individual proces.ing conditions.and the chemical compos.tion of a s.eel.s.60 is.a plate s.eel proces.ed in this.*** reproduce at the laboratory s.ale,a multi-s.age s.mulation was.developed which included a high temperature aus.enite deformation and an is.thermal *** effect of the applied cooling rate following intercritical deformation was.*** 1K/s.(typical indus.rial cooling) the micros.ructure was.s.milar to the reference s.mple,but included an intragranular ferrite *** was.due to differences.in proces.ing his.ory,and cons.dered to be linked to a larger prior aus.enite grain *** an accelerated cooling rate (15K/s.,acicular ferrite formed on s.ear bands.within the s.rained aus.enite *** s.ans.have been completed to provide further information about the micros.ructures.with band contras. able to identify the pearlite phas. at the s.owes. cooling *** is.a s.arting point from which to focus.on the ferrite morphologies.

关键词： intercritical deformation cooling rate laboratory s.mulation plate s.eel acicular ferrite

Jejunal diverticulos.s.found in a patient with long-s.anding pneumoperitoneum and ps.udo-obs.ruction on imaging:a cas. report

在线全文

学校读者我要写书评

暂无评论

Gas.roenterology Report 2016年第4期4卷 337-340,I0003页

作者： Carolyn Hanna John Mullinax mark s.Friedman Julian s.nchez Us. Mors.ni College of Medicine TampaFLUSA Department of s.rgical Oncology Moffitt Cancer CenterTampaFLUSA

s.all bowel diverticulos.s.is.a rare finding within the general population and jejunal diverticulos.s.s.ecifically,is.even *** manifes.ations.can range from pos.-prandial pain,cons.ipation and malabs.rption to s.rious.complications.s.ch as.gas.ro-intes.inal hemorrhage,perforation and acute intes.inal *** we des.ribe the cas. of an 81-yearold gentleman who pres.nted with a three-year his.ory of abdominal pain and weight *** unremarkable phys.cal examination and laboratory tes.s.pers.s.ent pneumoperitoneum and dilated loops.of s.all bowel were found on *** been given a diagnos.s.of s.all bowel bacterial overgrowth,the patient underwent caps.le endos.opy s.udy for further evaluation of his.s.all *** caps.le did not reach the colon and the patient never noted pas.ing the caps.le in his.s.ool s.,s.x months.pos.-procedure,a computed tomography(CT)s.an s.emed to reveal the retained *** exploratory laparotomy revealed 200 cm of atonic,dilated jejunum with impres.ive diverticula along the antimes.nteric *** cas. report is.an example of an unus.al s.t of pres.nting s.gns.and s.mptoms.of jejunal diverticulos.s.including pers.s.ent pneumoperitoneum,ps.udo-obs.ruction and s.all bowel bacterial overgrowth.A literature review has.revealed that thes. s.gns.have been pres.nt in other cas.s.of jejunal diverticulos.s.although the etiology and pathophys.ology is.not clearly unders.ood.

关键词： Jejunal diverticulos.s pneumoperitoneum ps.udo-obs.ruction

Nogo-A receptor internalization by cyclic adenos.ne monophos.hate in overcoming axonal growth inhibitors.after s.roke

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Res.arch 2022年第1期17卷 91-92页

作者： Rayudu Gopalakris.na Charlotte Lin mark s.Kindy William J.Mack Department of Integrative Anatomical s.iences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Department of Neurological s.rgery Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Department of Pharmaceutical s.iences College of PharmacyUniversity of South FloridaTampaFLUSA

Currently,there are no clinically proven drugs.for recovery from s.roke and other neuronal injuries.s.ch as.traumatic brain injury and s.inal cord *** therapy requires.axonal regeneration,which is.inhibited by divers. axonal growth inhibitors.s.ch as.Nogo-A,myelin-as.ociated glycoprotein(MAG),oligodendrocyte myelin glycoprotein(OMgp),and chondroitin s.lfate proteoglycans.Cs.Gs.(Chaudhry and Filbin,2007;Carmichael,2010;s.hwab and s.rittmatter,2014).

关键词： axonal injuries inhibited

Altered Mental s.atus.and Hyperammonemia after Overdos. of Valproic Acid with Therapeutic Valproic Acid Concentrations

在线全文

学校读者我要写书评

暂无评论

International Journal of Clinical Medicine 2014年第10期5卷 546-549页

作者： Evan s. s.hwarz mark Thoelke Department of Medicine Washington University School of Medicine St. Louis USA Divis.on of Emergency Medicine Washington University School of Medicine St. Louis USA

Valproic acid is.us.d in the treatment of multiple dis.rders. Advers. effects.from valproic acid include hepatotoxicity, hypotens.on, metabolic acidos.s. and decreas.d mental s.atus. Valproic acid als. caus.s.hyperammonemia. Many phys.cians.as.ume that this.is.due to a s.pratherapeutic valproic acid concentration;when in fact, it can occur with therapeutic valproic acid concentrations. This.is.becaus. the hyperammonemia may be related to carnitine deficiency and dis.uption of the urea cycle, which can both occur with therapeutic valproic acid concentrations. We report a patient pres.nted to the emergency department with alteration of mental s.atus.after inges.ing valproic acid for recreational purpos.s. who developed hyperammonemia with a therapeutic valproic acid concentration.

关键词： Valproic Acid L-Carnitine Levocarnitine Overdos. Toxicity

A comparative s.udy of the role of s.lute,potent particles.and ultras.nic treatment during s.lidification of pure Mg,Mg-Zn and Mg-Zr alloys

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnes.um and Alloys 2021年第3期9卷 829-839页

作者： Nagas.vamuni Balas.bramani Gui Wang mark A.Eas.on David H.s. John Matthew s.Dargus.h Centre for Advanced Materials.Proces.ing and Manufacturing(AMPAM) School of Mechanical and Mining EngineeringThe University of QueenslandBrisbane 4072Australia s.hool of Engineering RMIT UniversityCarlton3053 VICAustralia

Ultras.nic treatment(Us.)applied during the s.lidification of pure Mg,eutectic(Mg-Zn)and peritectic(Mg-Zr)alloys.was.inves.igated in order to explore the grain refinement *** dependent grain refinement is.obs.rved in pure Mg where decreas.ng the s.perheat temperature(at which Us. is.applied from above the melting temperature,TM)from 100℃to 40℃produces.s.gnificant refinement with a uniform grain *** pres.nce of s.lute reduces.the temperature dependence of the Us. refinement and excellent grain refinement is.obtained regardles. of the s.perheat temperature(100℃or 40℃)and even with the us. of preheated s.notrode in the Mg-6 wt.%Zn alloy.A further improvement in grain refinement is.achieved when the alloy contains.potent particles.that introduce additional nucleation of grains.in Mg-0.5 and 1.0 wt.%Zr alloys.producing an average grain s.ze of≤100μm).At 40℃s.perheat,Us. of Mg-Zn alloys.produces.excellent refinement(average grain s.zes.which is.normally achieved only with the addition of grain refining mas.er alloy in the as.cas. *** enhanced refinement obs.rved in the eutectic alloy is.explained through the undercooling impos.d by a relatively cold s.notrode combined with high frequency vibrations.and acous.ic *** advantages.of us.ng a cold s.notrode,a low s.perheat and s.lute are demons.rated for achieving s.gnificant refinement during s.lidification of Mg alloys.under Us. without or with a lower addition of grain refining mas.er alloys.

关键词： Grain refinement Mg-Zn alloy Mg-Zr alloy Ultras.nic treatment Interdependence Model s.lidification

A hybrid s.arm population of Pinus.dens.flora × P. s.lves.ris.inferred from s.quence analys.s.of chloroplas. DNA and morphological characters

在线全文

学校读者我要写书评

暂无评论

Journal of Fores.ry Res.arch 2013年第1期24卷 53-60页

作者： Young Hee Joung Jerry L. Hill Jung Oh Hyun Ding Mu Juchun Luo Do Hyung Lee Takayuki Kawahara Jeung Keun s.h mark s. Roh Chonnam National Univers.ty School of Biological Sciences & TechnologyGwangjuKorea Us.Department of Agriculture Forest ServiceDorena Genetic Resource CenterWashington State UniversityPullmanWA99164USA s.oul National Univers.ty College of Agriculture and Life SciencesSeoulKorea Chines. Academy of Agricultural s.ience Beijing Fores.ry Univers.ty College of Resources and Environment Yeungnam Univers.ty College of Natural ResourcesDepartment of Forest ResourcesGyeongsanKorea Hokkaido Res.arch Center Forestry and Forest Products Research InstituteSapporoJapan. Dankook Univers.ty School of Bio-Resource ScienceDepartment of Environment HorticultureCheonanKorea. Us.Department of Agriculture Agricultural Research ServiceUS National ArboretumFloral and Nursery Plants Research UnitBeltsvilleMD 20705USA.

To confirm a hybrid s.arm population of Pinus.dens.flora × P. s.lves.ris.in Jilin, China, we us.d needles.and s.eds.from P. dens.flora, P. s.lves.ris. and P. dens.flora × P. s.lves.ris.collected from natural s.ands.or experimental s.ations.to s.udy whether s.oot apex morphology of 4-year old s.edlings.can be correlated with the s.quence of a chloroplas. DNA s.mple s.quence repeat marker （cpDNA s.Rs.. Total genomic DNA was.extracted and s.bjected to s.quence analys.s.of the pine cpDNA s.R marker Pt15169. Res.lts.s.ow that morphological characters.from 4-year old s.edlings.did not correlate with s.quence variants.of this.marker. marker haplotypes.from all P. s.lves.ris.trees.had a CTAT element that was.abs.nt from all s.mpled P. dens.flora trees. However, both haplotype clas.es.involving this.ins.rtion/deletion element were found in a P. dens.flora × P. s.lves.ris.population and its.s.edling progeny. It was.concluded that the P. dens.flora × P. s.lves.ris.acces.ions.s.mpled from Jilin, China res.lted from bi-directional cros.es. as.evidenced by both s.ecies. cpDNA haplotypes.within the hybrid s.arm population.

关键词： P. s.lves.ris.var. s.lves.riformis chloroplas. DNA s.mples.quence repeat s.quencing hybrid s.arm population

Pillar des.gn and coal burs. experience in Utah Book Cliffs.longwall operations

在线全文

学校读者我要写书评

暂无评论

International Journal of Mining s.ience and Technology 2021年第1期31卷 33-41页

作者： Chris.opher mark Michael Gauna Mine s.fety and Health Adminis.ration Technical s.pport PittsburghPA 15236USA

Longwall mining has.exis.ed in Utah for more than half a *** of this.mining occurred at depths.of cover that s.gnificantly exceed thos. encountered by mos. other Us.longwall *** cover caus.s.high ground s.res.,which can combine with geology to create a coal burs. *** every longwall mine operating within the Utah’s.Book Cliffs.coalfield has.been affected by coal *** des.gn has.been a key component in the burs. control s.rategies.employed by mines.in the Book ***,mos. longwall mines.employed double-us. two-entry yield pillar ***-us. s.gnifies.that the gate s.s.em s.rves.firs. as.the headgate,and then later s.rves.as.the tailgate for the adjacent *** the 1996 burs. fatality at the Aberdeen Mine,the inter-panel barrier des.gn was.*** this.layout,a wide barrier pillar protects.each longwall panel from the previous.y mined panel,and each gate s.s.em is.us.d jus. *** paper documents.the deep cover longwall mining conducted with each type of pillar des.gn,together with the as.ociated coal burs. *** of the s.x longwall mining complexes.in the Book Cliffs.having a coal burs. his.ory is.des.ribed on a panel-by-panel *** analys.s.s.ows.that where the mining depth exceeded 450 m,each des.gn has.been employed for about 38000 total m of longwall panel *** double-us. yield pillar des.gn has.been us.d primarily at depths.les. than 600 m,however,while the inter-panel barrier des.gn has.been us.d mainly at depths.exceeding 600 *** its.greater depth of us.,the inter-panel barrier gate des.gn has.been as.ociated with about one-third as.much face region burs. activity as.the double-us. yield pillar des.gn.

关键词： Longwall Ground control Coal burs. Pillar des.gn Yield pillar

Reus.ng oxide-bas.d pulveris.d fly as. and medical was.e particles.to develop electroles. nickel compos.te coatings.Ni–P/fly as. and Ni–P/s.O2–Al2O3)

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals.Metallurgy and Materials 2020年第8期27卷 1147-1156页

作者： Franco Mayanglambam mark Rus.ell s.hool of Natural and Built Environment Queen’s University BelfastBelfast BT71NNUK Centre for Nanotechnology Indian Institute of Technology GuwahatiGuwahati 781038India

Recycling and reus.ng materials.from was.e have become a nexus.in the development of s.s.ainable materials.leading to more balanced *** this.s.udy,we developed a compos.te coating by co-depos.ting recycled ceramic particles.pulveris.d fly as.(PFA)and medical ceramics.MC),into a nickel–phos.horus.matrix us.ng a typical electroles. plating *** electron micros.opy(s.M)images.indicated well-dis.ers.d particles.in the Ni–P ***,compared with the MC particles.the PFA particles.were dis.ributed s.antily with a lower content in the matrix,which could be due to the les. impingement effect during the co-depos.tion.A modified micros.ructure with refined grains.was.obtained for the PFA-incorporated compos.te coating,as.s.en in the s.M *** X-ray diffraction res.lt of the MC-incorporated compos.te coating s.owed the formation of Nix s.y phas.s.in addition to the typical Ni3 P phas.s.for the heattreated electroles. Ni–P *** heat treatment,the PFA-reinforced compos.te coating,due to a modified micros.ructure,exhibited a higher microhardnes. up to HK0.05818,which is.comparable to that of the traditional s.C particle-embedded compos.te coating(HK0.05825).The findings.can potentially open up a new s.rategy to further advance the green approach for indus.rial s.rface engineering.

关键词： electroles. plating was.e ceramics fly as. particles micros.ructure microhardnes.