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Thermoregulation,incubator humidity,and skincare practices in appropriate for gestational age ultra-low birth weight infants:need for more evidence

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World Journal of Pediatrics 2024年第7期20卷 643-652页

作者： Umesh Mishra Deanne August Karen Walker Pranav R.Jani mark tracy Faculty of Medicine and Health University of SydneySydneyAustralia Department of Neonatology Westmead HospitalWestmeadNSWAustralia Grantley Stable Neonatal Unit Royal Brisbane and Women’s HospitalBrisbaneAustralia School of Nursing Midwifery and Social WorkUniversity of QueenslandBrisbaneAustralia Department of Newborn Care Royal Prince Alfred HospitalCamperdownAustralia

Background Although not universal,active care is being offered to infants weighing<500 g at birth,referred to as ultra-low birth weight(ULBW)infants appropriate for gestational *** infants have the greatest risk of dying or developing major *** infants face challenges related to fluid and heat loss as well as skin injury in the initial days of life from extreme anatomical and physiological immaturity of the *** there is an emerging literature on the outcomes of ULBW infants,there is a paucity of evidence to inform practice guidelines for delivering optimal care to this cohort of *** sources A comprehensive review of the literature was performed using the PubMed and Embase *** keywords included“thermoregulation or body temperature regulation”,“incubator humidity”,“skin care”,“infant,extremely low birth weight”and“ultra-low birth weight infants”.Results Evidences for thermoregulation,incubator humidity,and skincare practices are available for preterm infants weighing<1500 g at birth but not specifically for ULBW *** on thermoregulation,incubator humidity,or skincare practices had a small sample size and did not include a sub-group analysis for ULBW *** practice recommendations in ULBW infants are adopted from research in very and/or extremely low birth weight *** This narrative review focuses on challenges in thermoregulation,incubator humidity,and skincare practices in ULBW infants,highlights current research gaps and suggests potential developments for informing practices for improving health outcomes in ULBW infants.

关键词： Incubator humidity Neonatal intensive care unit Skincare Thermoregulation Ultra-low birth weight

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美国拉斯维加斯Rumor酒店

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现代装饰 2011年第1期 84-91页

作者： mark tracy David Marquardt 肖俊 Chemical Spaces

项目名称 Rumor Hotel项目地址美国拉斯维加斯设计单位 Chemical

关键词：拉斯维加斯美国酒店项目名称设计单位

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摩登艺术“家”

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现代装饰（家居） 2011年第7期 101-109页

作者： mark tracy David Marquardt 肖俊 Chemical Spaces

这栋五层楼的联排别墅位于旧金山著名的朗伯德街,设计师mark Tracv通过分层设计使每层空间都有它自己的特色。他这样描述道:"干净的线条以及充满现代感的设计赋予了空间明快的色彩和独特的个性。它有着位于旧金山市中心的优势地理,是人... 详细信息

这栋五层楼的联排别墅位于旧金山著名的朗伯德街,设计师mark Tracv通过分层设计使每层空间都有它自己的特色。他这样描述道:"干净的线条以及充满现代感的设计赋予了空间明快的色彩和独特的个性。它有着位于旧金山市中心的优势地理,是人们周末度假的好去处。"

关键词：联排别墅层空间旧金山市分层设计现代感主卧整体空间朗伯休息区混凝土地面

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绚彩飞舞

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现代装饰（家居） 2011年第10期 104-108页

作者： mark tracy 夏明媚肖俊 Chemical Spaces

该公寓位于拉斯维加斯City Center的Veer Towers住宅公寓的顶层。设计师mark tracy为其每一处表面都选用了上等材料,倾力打造一个集亲和、色彩绚烂、奢华和吸引力于一体的空间。其主要特色之一就是一组连接地而、墙面以及天花的玻璃马... 详细信息

该公寓位于拉斯维加斯City Center的Veer Towers住宅公寓的顶层。设计师mark tracy为其每一处表面都选用了上等材料,倾力打造一个集亲和、色彩绚烂、奢华和吸引力于一体的空间。其主要特色之一就是一组连接地而、墙面以及天花的玻璃马赛克艺术拼画,大小为四米乘四米。这组拼画以海洋蓝为基础色调。

关键词：玻璃马赛克组拼海洋蓝 tracy 维加拉斯贴面砖照明功能 elegant 室内光

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同时测定三聚氰胺和三聚氰酸

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实验与分析 2009年第1期 42-44页

作者： Leo Wang Stacy M. Henday Xiaodong Liu mark tracy William C. Schnute Dionex美国公司

本文通过LC-MS和戴安公司的混合基质柱WAX-1，对宠物食品和生物样品中的三聚氰胺和三聚氰酸进行了有效的检测，取得了理想的实验结果。

关键词：三聚氰酸三聚氰胺同时测定 LC-MS 混合基质戴安公司生物样品宠物食品

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The Game-Theoretical Model of Using Insecticide-Treated Bed-Nets to Fight Malaria

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Applied Mathematics 2016年第9期7卷 852-860页

作者： mark Broom Jan Rychtář tracy Spears-Gill Department of Mathematics City University London Northampton Square London UK Department of Mathematics and Statistics The University of North Carolina at Greensboro Greensboro USA Department of Biostatistics University of North Carolina at Chapel Hill Chapel Hill USA

Malaria infection is a major problem in many countries. The use of the Insecticide-Treated Bed-Nets (ITNs) has been shown to significantly reduce the number of malaria infections;however, the effectiveness is often jeopardized by improper handling or human behavior such as inconsistent usage. In this paper, we present a game-theoretical model for ITN usage in communities with malaria infections. We show that it is in the individual’s self interest to use the ITNs as long as the malaria is present in the community. Such an optimal ITN usage will significantly decrease the malaria prevalence and under some conditions may even lead to complete eradication of the disease.

关键词： Game Theory Malaria Prevention Optimal Strategy Epidemic Modelling SIS Model

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Alterations in Caspase-3 in Juvenile Rats Treated Neonatally with Domoic Acid

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Journal of Behavioral and Brain Science 2016年第9期6卷 357-363页

作者： mark A. Robbins Catherine L. Ryan tracy A. Doucette Department of Biology University of Prince Edward Island Charlottetown Canada Department of Psychology University of Prince Edward Island Charlottetown Canada

The clinical presentation of schizophrenia involves a variety of symptoms, which in many cases include hallucinations and delusions. Experimentally revealed alterations in both pre-pulse inhibition (PPI) and latent inhibition (LI) are also apparent in individuals afflicted with this disorder. Many have speculated that altered synaptic connections are, in part, responsible for this subset of behavioral abnormalities. We have previously reported that neonatal chronic low-dose injections of domoic acid (DOM) produce adult rats with deficits in PPI and LI. The current study was conducted to determine whether this toxin-treatment would alter the degree of apoptosis occurring in the developing brain. Results revealed significant decreases in caspase-3 within the right prelimbic cortex (PrL) in both male and female DOM-treated rats suggesting that even modest alterations in glutamate (Glu) signaling during critical periods of central nervous system (CNS) maturation will modify ontogenetic processes in the prefrontal cortex (PFC) of the juvenile rat.

关键词： Neonatal Rat Domoic Acid Prefrontal Cortex Apoptosis Caspase-3

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Does a large prostate size,small lesion volume,or long needle distance from the probe to the lesion reduce magnetic resonance imaging–targeted cancer detection?

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Current Urology 2024年第2期18卷 144-147页

作者： mark D.Bevill Justin N.Drobish Kevin J.Flynn Maheen Rajput Catherine Metz Chad R.tracy Paul T.Gellhaus Department of Urology University of Iowa Carver College of MedicineIowa CityIAUSA Department of Radiology University of Iowa Carver College of MedicineIowa CityIAUSA

Background:We aimed to evaluate whether large prostate size,small lesion volume,or long lesion distance from the ultrasound probe tip would decrease cancer detection in transrectal magnetic resonance imaging(MRI)–targeted *** and methods:Patients who underwent MRI-targeted biopsy at our institution between May 2017 and August 2019 were enrolled in a prospective *** to 5 cores were obtained from≥2 prostate imaging reporting and data system v2 lesions.A multivariable model was created that included needle distance to the lesion,prostate specific antigen,prostate imaging reporting and data system,lesion volume,and prostate ***:A total of 377 patients with 533 lesions underwent a biopsy during the study period.A total of 233(44%)lesions were positive for prostate cancer,and 173(32%)lesions had clinically significant prostate *** mean needle distance to the lesion was 11.7mm(interquartile range,7.6–15.5mm).The likelihood of obtaining a positive core on biopsy decreased as the distance fromthe ultrasound probe increased for all prostate cancers and clinically significant prostate cancer(p=0.018 and p=0.004,respectively).Every 10mmfrom the rectum,there was an 8%–10%decrease in the rate of cancer ***,as the prostate volume increased,the odds of obtaining a positive core also decreased(p=0.039).There was no significant association between the lesion size and amount of cancer obtained on ***:Our data showed that transrectal MRI-targeted biopsy cancer detection modestly decreased the lesion from the ultrasound probe and with a large prostate volume but could not prove that lesion volume was a significant predictor of the amount of cancer detected.

关键词： Prostate cancer Biopsy Magnetic resonance imaging

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Temporal Memory Dysfunction and Alterations in Tyrosine Hydroxylase Immunoreactivity in Adult Rats Following Neonatal Exposure to Domoic Acid

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Neuroscience & Medicine 2013年第1期4卷 29-35页

作者： mark A. Robbins Catherine L. Ryan Amber L. Marriott tracy Ann Doucette Departments of Biology University of Prince Edward Charlottetown Canada Departments of Psychology University of Prince Edward Charlottetown Canada

The purpose of the present study was to determine whether early alterations in glutamate signaling, via daily injections of the glutamate agonist, domoic acid (DOM;20 μg/kg), during a critical period of CNS development (PND 8 - 14), would result in temporal memory deficits and/or alterations in tyrosine hydroxylase (TH) immunoreactivity. As adults, subjects were assessed for temporal memory ability using a recency discrimination paradigm. Both number and duration of exploratory contacts directed at familiar objects, differing by one hour in recall delay, were measured. Analyses revealed that DOM-treated females demonstrated temporal memory dysfunction, as evidenced in a significantly lower proportion of total exploratory behaviour directed toward the remote object. Integrity of the dopamine system was assessed using immunohistochemistry to examine TH immunoreactivity in the prefrontal cortex (PFC) and nucleus accumbens (NAcc). Sections obtained from DOM-treated males had significantly less TH immunoreactivity in the right mPFC, while DOM-treated females had significantly greater TH immunoreactivity in the left core and right shell of the NAcc. These findings are discussed in context of early alterations to glutamate signaling in the development of human neuropsychiatric disorders.

关键词： Domoic Acid Glutamate Schizophrenia Animal Models Neurodevelopmental Disorders

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Implementation of the FAIR Data Principles for Exploratory Biomarker Data from Clinical Trials

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Data Intelligence 2021年第4期3卷 630-661页

作者： Alexander Arefolov Laura Adam Shoshana Brown Yelena Budovskaya Cong Chen Diya Das Chen Farhy Rebecca Ferguson Hongmei Huang Kimberly Kanigel Christina Lu Oksana Polesskaya tracy Staton Rajeev Tajhya Maryann Whitley Jee-Yeon Wong Xiangpei Zeng mark McCreary Rancho BioSciences LLC. San DiegoCA 92127USA Development Sciences Informatics Genentech Inc.South San FranciscoCA 94080-4990USA Development Sciences OMNI-Biomarker Development Genentech Inc.South San FranciscoCA 94080-4990USA

The FAIR data guiding principles have been recently developed and widely adopted to improve the Findability,Accessibility,Interoperability,and Reuse of digital assets in the face of an exponential increase of data volume and *** FAIR data principles have been formulated on a general level and the technological implementation of these principles remains up to the industries and organizations working on maximizing the value of their ***,we describe the data management and curation methodologies and best practices developed for FAIRification of clinical exploratory biomarker data collected from over 250 clinical *** discuss the data curation effort involved,the resulting output,and the business and scientific impact of our ***,we propose prospective planning for FAIR data to optimize data management efforts and maximize data value.

关键词： Data management Data curation Clinical studies FAIR data Biomarkers Data model Metadata Data standards Data governance

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