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A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States

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Translational Neurodegeneration 2013年第1期2卷 183-194页

作者： David A geier Brian S Hooker Janet K Kern Paul G King Lisa K Sykes mark r geier The Institute of Chronic Illnesses Inc 14 Redgate CtSilver SpringMDUSA Simpson University ReddingCAUSA University of Texas Southwestern Medical Center at Dallas DallasTXUSA CoMeD Inc Silver SpringMDUSA

Background:Autism spectrum disorder(ASD)is defined by standardized criteria of qualitative impairments in social interaction,qualitative impairments in communication,and restricted and stereotyped patterns of behavior,interests,and activities.A significant number of children diagnosed with ASD suffer a loss of previously-acquired skills,which is suggestive of neurodegeneration or a type of progressive encephalopathy with an etiological pathogenic basis occurring after *** date,the etiology of ASD remains under debate,however,many studies suggest toxicity,especially from mercury(Hg),in individuals diagnosed with an *** present study evaluated concerns about the toxic effects of organic-Hg exposure from Thimerosal(49.55%Hg by weight)in childhood vaccines by conducting a two-phased(hypothesis generating/hypothesis testing)study with documented exposure to varying levels of Thimerosal from ***:A hypothesis generating cohort study was undertaken to evaluate the relationship between exposure to organic-Hg from a Thimerosal-containing Diphtheria-Tetanus-acellular-Pertussis(DTaP)vaccine in comparison to a Thimerosal-free DTaP vaccine administered,from 1998 through 2000,for the risk of ASD as reported in the Vaccine Adverse Event reporting System(VAErS)database(phase I).A hypothesis testing case–control study was undertaken to evaluate the relationship between organic-Hg exposure from Thimerosal-containing hepatitis B vaccines administered at specific intervals in the first six months of life among cases diagnosed with an ASD and controls born between 1991 through 1999 in the Vaccine Safety Datalink(VSD)database(phase II).results:In phase I,it was observed that there was a significantly increased risk ratio for the incidence of ASD reported following the Thimerosal-containing DTaP vaccine in comparison to the Thimerosal-free DTaP *** phase II,it was observed that cases diagnosed with an ASD were significantly more likely than controls to rece

关键词： Autism Ethylmercury Merthiolate Thimerosal Thiomersal Vaccine

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IH型结构的后加速器

核技术 2002年第6期25卷 425-429页

作者：陈明 H.Morinaga W.Nitsche r.geier 中国科学院上海原子核研究所上海201800 德国慕尼黑技术大学物理系E17研究所 d85747

在 4年时间内和德国慕尼黑技术大学合作研制成一台Interdigital-H型加速结构 (以下简称IH型结构 )的射频直线后加速器[1] 。叙述了该加速器的原理和结构 ,间隙电压的调整 ,束流动力学 ,射频系统及聚束器。在 84 .2MHz的谐振频率下 ,输入... 详细信息

在 4年时间内和德国慕尼黑技术大学合作研制成一台Interdigital-H型加速结构 (以下简称IH型结构 )的射频直线后加速器[1] 。叙述了该加速器的原理和结构 ,间隙电压的调整 ,束流动力学 ,射频系统及聚束器。在 84 .2MHz的谐振频率下 ,输入 3kW射频功率 ,它可以把质量数为 3的离子的能量从 340keV提高到 1.74MeV ,有效分路阻抗高达 4 0 8MΩ/m。用H+ 3 束一次调试出束成功 ,输出H+ 3 离子的能量达到设计值。该后加速器采用的二谐波双漂移聚束器 ,把束流聚集成宽度为 36 0 ps的束团 ,使加速腔的接受度提高到 2 4 0°。由于采用了双间隙型λ/ 4同轴腔结构 ,分路阻抗是慕尼黑以前所用的单间隙型的 4倍 ,而聚束系统占用的束线长度缩短到 2 0 %。

关键词： Interdigital-H型加速结构二谐波双漂移聚束器双间隙同轴腔

Weed Control and Crop Safety with Premixed <i>S</i>-Metolachlor and Sulfentrazone in Sunflower

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American Journal of Plant Sciences 2012年第11期3卷 1625-1631页

作者： Seshadri S. reddy Phillip W. Stahlman Patrick W. geier Curtis r. Thompson 2014 Throckmorton Hall Kansas State University Manhattan USA Agricultural research Center Kansas State University Hays USA

A preliminary study conducted in the central USA near Colby and Hays, Kansas (KS) in 2010 indicated a premix of S-metolachlor & sulfentrazone codenamed F7583 (Broadaxe?) had good potential for use in sunflower (Helianthus annuus L.). Additional studies were conducted in 2011 at Colby, Hays, Manhattan, KS to refine rate and application timing of F7583 for weed control and crop safety. Four rates of F7583 (860, 1100, 1350 and 1840 g·ha-1) were compared to single rates of S-metolachlor and pendimethalin, and applied 21 days preplant versus preemergence (PrE). F7583 at ≥1100 g·ha-1 applied preplant or PrE controlled Palmer amaranth (Amaranthus palmeri S. Wats.) and kochia [Kochia scoparia (L.) Schrad.] ≥95% and 100%, respectively in neutral pH soils. In slightly acidic soils, PrE application of F7583 was more effective against Palmer amaranth and grass weeds compared to preplant application. No benefit was gained by increasing the rate of F7583 from 1100 to 1350 g·ha-1 at either application timing. Puncturevine (Tribulus terrestris L.) control was not commercially satisfactory with F7583 at any rate or time of application. Both S-metolachlor at 1070 g·ha-1 and pendimethalin at 1600 g·ha-1 applied either preplant or PrE were considerably less effective on all three broadleaf weeds compared to F7583 treatments. Individually, S-metolachlor and pendimethalin were more effective when applied PrE compared to preplant application. F7583 did not reduce sunflower plant population or visibly injure sunflower anytime during the season.

关键词： Broadaxe Sulfentrazone S-Metolachlor Sunflower Crop Injury Kochia Palmer Amaranth

CCIE路由与交换认证考试指南第2版影印版

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Age-Dependency of Clinical Characteristics of Patients Participating Cardiovascular rehabilitation results from the German

丛书名： Cisco职业认证培训系列

2007年

作者：（美）WENDELL ODOM JIM geier NArEN MEHTA

本书讲述了Cisco认证考试CCIE路由与交换(r&S)笔试所涉及的全部内容,此外还介绍了CCIE服务提供商书面考试中与网络相关的内容。全书内容包括网络概念、设备操作、桥接与局域网(LAN)交换技术、广域网(WAN)、IP及IP路由选择协议、网络安... 详细信息

ISBN: (数字)9787115155085

ISBN: (纸本)7115155089

本书讲述了Cisco认证考试CCIE路由与交换(r&S)笔试所涉及的全部内容,此外还介绍了CCIE服务提供商书面考试中与网络相关的内容。全书内容包括网络概念、设备操作、桥接与局域网(LAN)交换技术、广域网(WAN)、IP及IP路由选择协议、网络安全性以及多服务网络等。

关键词：资格考核工程技术人员英文路由选择自学参考资料计算机网络

来源：畅想之星图书光盘版（南... 评论

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Open Journal of Therapy and rehabilitation 2014年第4期2卷 207-216页

作者： roland Nebel Michael Marx Michael geier Brigitte Buran-Kilian Taoufik Ouarrak Manju Guha Gregor Sauer Gerd Bonner Harry Hahmann ralf Jordan Michaela Julia Engelhard Bernhard rauch Birna Bjarnason-Wehrens Medicos.Osnabrück GmbH OsnabruckGermany Zentrum fur Gefaßmedizin Bonn KaRO GmbH WaldbrolBonnGermany Ambulante rehabilitation für Herzpatienten Evangelisches Krankenhaus Bergisch GladbachBergisch GladbachGermany Schwerpunktreha Ambulante kardiologische RehabilitationBonnGermany Stiftung Institut fur Herzinfarktforschung LudwigshafenGermany reha-Klinik am Sendesaal BremenGermany Helios rhein Klinik DuisburgGermany Freiburg im Breisgau Germany Klinik Schwabenland IsnyGermany 1 Kardiologische Gemeinschaftspraxis an der rheinklinik DuisburgGermany 1 Deutsche Sporthochschule Koln CologneGermany

Background: Cardiovascular rehabilitation in Germany traditionally is offered as inpatient service often located far from patient’s residence, and ambulatory rehabilitation still represents a minority. The German registry of Ambulatory Cardiac rehabilitation (KArrEE) was designed to contribute to rehabilitation quality assurance and to evaluate clinical characteristics of patients participating in ambulatory rehabilitation centers. Methods: In four ambulatory rehabilitation centers 2989 patients were consecutively registered from 2008 to 2011 and evaluated with respect to social status, cardiovascular diagnoses and risk factors, psychological status, medication and short term clinical and social outcome. results: Most patients referred to the ambulatory cardiac rehabilitation had an acute cardiovascular event, with patients after acute coronary syndrome representing the majority (59.9%). Female were strongly underrepresented (16.7%). Patient’s clinical characteristics varied with the age groups evaluated ( 70 years). Whereas the reported physical inactivity, overweight and cigarette smoking was declining with age, diabetes and hypertension significantly increased. Furthermore the reported and evaluated psychosocial stress was declining with age. regarding the group of patients still employed, 43.5 % were estimated as fit for work directly at the end of the rehabilitation program, whereas a stepwise reintegration into employment was performed in 16.7%. The majority of patients were transferred to ambulatory heart groups or other forms of after care for stabilizing regular physical activity. Conclusions: The large variation of the characteristics of patients participating cardiac rehabilitation underscore the need of an individualized approach for a successful implementation of secondary prevention and reintegration of these patients into their social life.

关键词： Ambulatory Cardiac rehabilitation Cardiovascular risk Factors Acute Coronary Syndrome