γδT cells are the major initial IL-17 producers in ***-17 regulates the expansion and recruitment of neutrophils and monocytes to initiate the inflammatory *** acute infection,a swift IL-17 response must be elicited...
γδT cells are the major initial IL-17 producers in ***-17 regulates the expansion and recruitment of neutrophils and monocytes to initiate the inflammatory *** acute infection,a swift IL-17 response must be elicited without prior antigen ***,what inducesγδT cells to mount an IL-17 response is *** has been argued that these responses are too rapid and robust to be antigen-specific,and thatγδT cells provide an"innate"source of IL-17.I will discuss experiments indicating that antigen recognition is necessary to activateγδT cells and to initiate
Background:Guidelines recommend that adolescents should accumulate an average of 60 min per day of moderate-to-vigorous physical activity(MVPA).However,using only this cut-off could hide important *** instance,from a ...
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Background:Guidelines recommend that adolescents should accumulate an average of 60 min per day of moderate-to-vigorous physical activity(MVPA).However,using only this cut-off could hide important *** instance,from a population-level point of view,increasing physical activity for those with no or low physical activity could provide more health benefits than increasing physical activity for those with intermediate ***,including a more sensitive cut-point of≥1 days per week could be an additional strategy for identifying those with low access/opportunities for physical activity ***,the current study aims to estimate the prevalence of≥60 min of MVPA≥1 days per week among adolescents globally,and to describe any relevant gender ***:We used representative datasets from 146 countries/territories collected between 2003 and *** was *** were grouped into younger(≤14 years old)and older(>14 years old)*** Poisson regression models were used to identify the relative differences in≥60 min of MVPA≥1 days per week between boys and girls,and random-effects meta-analysis models were used to identify the pooled *** were stratified by country and ***:Approximately 80%of both younger and older adolescents reported≥60 min of MVPA≥1 days per *** prevalence was≥94%in Europe and Central Asia and North America,while the estimates for the other regions were14y)=1.09(95%CI:1.08-1.10)).Conclusion:Approximately 8 out of 10 adolescents reported accumulating≥60 min of MVPA≥1 days per week,with notable differences between *** differences were observed in several countries,especially among the oldest *** fo
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