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A systematic review of the management of acute superior mesenteric vein thrombosis in adults

Journal of Pancreatology 2020年第3期3卷 111-120页

作者： Eimear Phoenix Jonathan Beck Timothy J.Patterson Robert A.J.Spence mark a.taylor Gary M.Spence Department of General Surgery Ulster Hospital DundonaldDundonaldUK Hepatobiliary Surgical Unit Mater Infirmorum HospitalBelfastUK

Background:Acute thrombosis of the superior mesenteric vein(SMV)is a rare but potentially catastrophic *** separate from portal venous thrombosis due to a higher proportion of associated thrombophilic disorders and intestinal infarction,SMV thrombosis warrants a distinct approach to *** aim of this review is to report the evidence for current ***:A systematic review was carried out in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses *** clinical trials databases and 4 trial registries were *** search was not limited by language or study type,but was limited to an adult population(18 years and above).The search period was between January 1,2000 and February 28,*** review was registered in the PROSPERO database:*** was assessed using the ROBINS-I ***:A total of 7989 studies were identified,resulting in 19 observational studies being *** studies reported on anti-coagulation,1 reported on anti-coagulation plus endovascular thrombectomy,9 reported on thrombolysis,and 10 reported on the role of *** assessment showed that confounding was a significant area of potential *** review has reported that the management of SMV thrombosis is centered around a patients’perceived hemodynamic *** there is evidence of perforation or peritonism then surgical intervention is ***,anti-coagulation or thrombolysis is ***:The data reported were compared with,and added to,that presented by the European Society for Vascular Surgery 2017 *** the source data were heterogenous,with multiple sources of bias and statistical comparison was not achievable.

关键词： Acute mesenteric ischemia Mesenteric vein Thrombus

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Disparities across the CREOG Districts —Variations of Wellness and Inclusivity Efforts in Obstetrics & Gynecology Residency Websites between Two Consecutive Years

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Advances in Reproductive Sciences 2024年第1期12卷 14-22页

作者： taylor Gatson mark Alvarez Malik Mays Rachel Coleman Dani Zoorob School of Medicine Louisiana State University (LSU) Health Sciences Center Shreveport USA Department of Obstetrics and Gynecology Louisiana State University (LSU) Health Sciences Center Shreveport USA College of Medicine and Life Sciences University of Toledo Toledo USA

Background: Few studies have focused on the geographic and chronologic assessment of inclusivity and wellness in Obstetrics and Gynecology residency websites across the US. Objective: To identify variations in wellness and inclusivity website depictions across CREOG districts over the past two years. Methods: This is a cross-sectional analysis of the websites of ACGME-accredited OB/GYN residency programs across the United States between April 2022 and April 2023. The assessment was based on a compilation of 22 attributes devised and piloted by 49 medical students. A racially, geographically, and gender-diverse cohort of 11 students performed data collection. Results: A total of 560 websites were analyzed over two years. Wellness efforts remained unchanged in both years (website content, dedicated support personnel, and group activities). In 2023, a reduction in referencing of wellness (22%) and inclusivity (30%) occurred in leadership messaging. However, a 7% increase in the use of inclusive pronouns was noted. A reduction in gender diversity was identified (9% in faculty, 5% in residents), with programs favoring female-only teams. Similarly, a 7% reduction in the number of underrepresented in medicine faculty and residents was noted. A 15% reduction was noted in curricula referencing inclusivity in their mission statement and inclusivity focused research. Conclusions: This study suggests the variations across websites relative to inclusivity and wellness over the past two years. Updated websites may provide an accurate reflection of the offerings of programs and their investment in wellness and inclusivity across the nation.

关键词： Diversity Gynecology Inclusion Obstetrics Residency

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Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed

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Infectious Diseases of Poverty 2024年第1期13卷 85-89页

作者： Robert Colebunders Joseph Nelson Siewe Fodjo Olivia Kamoen Luis-Jorge Amaral Amber Hadermann Chiara Trevisan mark J.taylor Julia Gauglitz Achim Hoerauf Yasuaki Sato Katja Polman Maria-Gloria Basanez Dan Bhwana Thomson Lakwo Gasim Abd-Elfarag Sebastien D.Pion Global Health Institute University of AntwerpAntwerpBelgium Department of Neurology Heilig Hart ZiekenhuisLierBelgium Department of Public Health Institute of Tropical MedicineAntwerpBelgium Liverpool School of Tropical Medicine LiverpoolUK Department of Computer Science University of AntwerpAntwerpBelgium Institute of Medical Microbiology Immunology and ParasitologyUniversity Hospital BonnBonnGermany German Center for Infection Research(DZIF) Partner Site Bonn-CologneBonnGermany School of Global Humanities and Social Sciences Nagasaki UniversityNagasakiJapan MRC Centre for Global Infectious Disease Analysis and London Centre for Neglected TropicalDisease Research Department of Infectious Disease EpidemiologySchool of Public HealthImperial College LondonLondonUK National Institute for Medical Research TangaTanzania Vector Control Division Ministry of HealthKampalaUganda School of Public Health University of JubaJubaSouth Sudan Access for Humanity JubaSouth Sudan French National Research Institute for Sustainable Development MontpellierFrance

Background There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of onchocerciasis-associated epilepsy (OAE). The aim of this paper is to provide an update on the new knowledge about OAE and to propose recommendations to the World Health Organization how to address this public health *** text During the 2nd International Workshop on OAE held on 19-21 September, 2023, in Antwerp, Belgium, participants recognised OAE as a substantial yet neglected public health problem, particularly in areas of sub-Saharan Africa where onchocerciasis remains hyperendemic. Evidence from prospective population-based studies suggest that strengthening onchocerciasis elimination efforts leads to a significant reduction of OAE incidence. There is a need to validate an OAE case definition to estimate the burden of disease and identify onchocerciasis-endemic areas requiring intensification of onchocerciasis elimination programmes and integration of epilepsy care. It is expected that raising awareness about OAE will boost the population uptake of ivermectin. The implementation of a community-based epilepsy treatment programme offering free anti-seizure medications (ASMs) has shown high effectiveness in reducing the frequency of seizures and improving the overall quality of life of people with *** To reduce OAE burden, enhanced collaboration between onchocerciasis and mental health programmes at community, national, and international levels is required. Urgent efforts are needed to ensure the uninterrupted provision of free ASMs in onchocerciasis-endemic areas. Furthermore, OAE should be included in the quantification of the onchocerciasis disease burden.

关键词： Onchocerciasis Morbidity Burden of disease Prevention Ivermectin Epilepsy Nodding syndrome Treatment Children Policy

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Continuous Flow Intersection Performance Measures Using Connected Vehicle Data

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Journal of Transportation Technologies 2022年第4期12卷 861-875页

作者： Enrique Saldivar-Carranza Howell Li mark taylor Darcy Michael Bullock Purdue University West Lafayette USA Utah Department of Transportation Salt Lake City USA

Continuous flow intersections (CFIs), also known as displaced left turns (DLTs), are a type of alternative intersection designed to improve operations at locations with heavy left-turn movements by reallocating these vehicles to the left side of opposing traffic. Currently, simulation is commonly used to evaluate operational performance of CFIs. However, this approach requires significant on-site data collection and is highly dependent on the analyst’s ability to correctly model the intersection and driver behavior. Recently, connected vehicle (CV) trajectory data has become widely available and presents opportunities for the direct measurement of traffic signal performance measures. This study utilizes CV trajectory data to analyze the performance of a CFI located in West Valley City, UT. Over 4500 trajectories and 105,000 GPS points are analyzed from August 2021 weekday data. Trajectories are linear-referenced to generate Purdue Probe Diagrams (PPDs) and extended PPDs to estimate split failures (SF), arrivals on green (AOG), traditional Highway Capacity Manual (HCM) level of service (LOS), and the distribution of stops. The estimated operational performance showed effective progression during the PM peak period at all the critical internal storage areas with AOG levels at exit traffic signals between 83% and 100%. In contrast, all external approaches with longer queue storage areas had AOG values ranging from 2% to 81% during the same time period. The presented analytical techniques and summary graphics provide practitioners with tools to evaluate the performance of any CFI where CV trajectories are available without the need for on-site data collection.

关键词： Performance Measures Connected Vehicles Trajectories Continuous Flow Intersection Displaced Left Turn

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A phaseⅡprospective trial of photobiomodulation therapy in limiting oral mucositis in the treatment of locally advanced head and neck cancer patients

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2022年第4期8卷 345-354页

作者： Janielle K.-a.taylor Leila J.Mady Khalil Baddour Uzoma K.Iheagwara Shuyan Zhai James P.Ohr Daniel P.Zandber Vikram C.Gorantla Robert L.Ferris Seungwon Kim Umamaheswar Duvvuri mark W.Kubik Shaum Sridharan Jonas T.Johnson Karen D.Holeva Annette E.Quinn David A.Clump School of Medicine University of PittsburghPittsburghPennsylvaniaUSA Department of Otorhinolaryngology—Head and Neck Surgery University of PennsylvaniaPhiladelphiaPennsylvaniaUSA Department of Otolaryngology—Head and Neck Surgery UPMCPittsburghPennsylvaniaUSA UPMC Department of Radiation Oncology UPMCPittsburghPennsylvaniaUSA Biostatistics UPMC Hillman Cancer CenterPittsburghPennsylvaniaUSA Department of Medicine Division of Hematology/OncologyUPMC Hillman Cancer CenterPittsburghPennsylvaniaUSA Department of Immunology UPMCPittsburghPennsylvaniaUSA Department of Plastic and Reconstructive Surgery University of Pittsburgh Medical CenterPittsburghPennsylvaniaUSA

Objective:This study aimed to compare the historical incidence rate of severe oral mucositis(OM)in head and neck cancer patients undergoing definitive concurrent chemoradiation therapy(CRT)versus a prospective cohort of patients with locally advanced head and neck squamous cell carcinoma(HNSCC)treated with prophylactic photobiomodulation therapy(PBMT).Methods:This US-based,institutional,single-arm,phaseⅡprospective clinical trial was initiated in 50 patients(age≥18 years,Karnofsky Performance Scale Index>60,with locally advanced HNSCC(excluding oral cavity)receiving definitive or adjuvant radiation therapy(RT)with concurrent platinum-based chemotherapy(CT).PBMT was delivered three times per week throughout RT utilizing both an intraoral as well extraoral delivery *** outcome measure was incidence of severe OM utilizing both the National Cancer Institute Common Toxicity Criteria,version 4.0(NCI-CTCAE)Grade≥3 and the World Health Organization Mucositis Grading Scale(WHO)Grade≥3 versus historical controls;secondary outcome measures included time to onset of severe OM following therapy ***:At baseline,all patients included in final analysis(N=47)had OM Grade *** RT and CT dose was(66.3±5.1)Gy and(486.1±106.8)mg/m ^(2),*** OM was observed in 11 of 47 patients(23%,confidence interval:12,38).OM toxicity grade trended upward during treatment,reaching a maximum at 7 weeks(WHO:1.8 ***-CTCAE:1.7).Subsequently,OM grade returned to baseline 3 months following completion of *** mean time to onset of severe OM was(35±12)*** mean time to resolution of severe OM was(37±37)***:Compared to historical outcomes,PBMT aides in decreasing severe OM in patients with locally advanced *** represents a minimally invasive,prophylactic intervention to decrease OM as a major treatment-related side effect.

关键词： chemoradiotherapy oral mucositis photobiomodulation therapy squamous cell carcinoma of head and neck

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Associations between meeting 24-hour movement guidelines and quality of life among children and adolescents with autism spectrum disorder

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Journal of Sport and Health Science 2023年第1期12卷 73-86页

作者： Chuidan Kong Aiguo Chen Sebastian Ludyga Fabian Herold Sean Healy Mengxian Zhao Alyx taylor Notger G.Muller Arthur F.Kramer Sitong Chen mark S.Tremblay Liye Zou Body-Brain-Mind Laboratory School of PsychologyShenzhen UniversityShenzhen 518061China College of Physical Education Yangzhou UniversityYangzhou 225127China Department of Sport Exercise and HealthUniversity of BaselBasel 4052Switzerland Research Group Degenerative and Chronic Diseases MovementFaculty of Health Sciences BrandenburgUniversity of PotsdamPotsdam 14476Germany Community Health Academic Group School of NursingPsychotherapy and Community HealthDublin City UniversityDublin 9Ireland School of Rehabilitation Sport and PsychologyAECC University CollegeBournemouthBH52DFUK Research Group Neuroprotection German Center for Neurodegenerative Diseases(DZNE)Magdeburg 39120Germany Center for Behavioral Brain Sciences(CBBS) Magdeburg 39118Germany Center for Cognitive and Brain Health Northeastern UniversityBostonMA 02115USA Beckman Institute University of Illinois at Urbana-ChampaignChampaignIL 61820USA Institute for Health and Sport Victoria UniversityMelbourne 8001Australia Healthy Active Living and Obesity Research Group CHEO Research InstituteOttawaOntario K1H8L1Canada Department of Pediatrics University of OttawaOttawaOntario K1N 6N5Canada

Background:The Canadian 24-hour movement behavior(24-HMB)guidelines suggest that a limited amount of screen time use,an adequate level of physical activity(PA),and sufficient sleep duration are beneficial for ensuring and optimizing the health and quality of life(QoL)of children and ***,this topic has yet to be examined for children and adolescents with autism spectrum disorder(ASD)*** aim of this cross-sectional observational study was to examine the associations between meeting 24-HMB guidelines and several QoLrelated indicators among a national sample of American children and adolescents with ***:Data were taken from the 2020 *** Survey of Children’s Health ***(n=956)aged 617 years and currently diagnosed with ASD were *** exposure of interest was adherence to the 24-HMB *** were QoL indicators,including learning interest/curiosity,repeating grades,adaptive ability,victimization by bullying,and behavioral *** variables were described with unweighted sample counts and weighted ***,sex,race,preterm birth status,medication,behavioral treatment,household poverty level,and the educational level of the primary caregivers were included as *** ratio(OR)and 95%confidence interval(95%CI)were used to present the strength of association between adherence to 24-HMB guidelines and QoL-related ***:Overall,452 participants(45.34%)met 1 of the 3 recommendations,216(22.65%)met 2 recommendations,whereas only 39 participants(5.04%)met all 3 *** with meeting none of the recommendations,meeting both sleep duration and PA recommendations(OR=3.92,95%CI:1.639.48,p<0.001)or all 3 recommendations(OR=2.11,95%CI:1.034.35,p=0.04)was associated with higher odds of showing learning interest/*** both screen time and PA recommendations(OR=0.15,95%CI:0.040.61,p<0.05)or both sleep duration and PA recommendations(OR=0.24,95

关键词： 24-hour movement guidelines Autism spectrum disorder Physical activity Quality of life

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充实生活的五大要素

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疯狂英语（初中天地） 2023年第2期 19-20页

作者： mark taylor 不详

人生在世,短短几十载,我们要尽量让自己快乐而充实地度过一生。希望本文提出的充实生活的五大要素对你有所帮助。

关键词：五大要素充实生活人生在世

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Scoping review: obese elderly women with breast cancer and physical activity/exercise

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Global Health Journal 2022年第3期6卷 129-135页

作者： mark Stephan Felix Department of Society and Health Faculty of Social Sciences and HumanitiesMahidol UniversitySalayaNakhon Pathom 73170Thailand

Objective:Obesity and breast cancer(BC)are diseases of concern,especially within the context of an aging *** scoping review is aimed at mapping out the literature on the subject of elderly women(EW)with breast cancer,obesity and physical activity/exercise(PAE)to identify gaps in the present extant literature,and to suggest directions for future *** sources:A total of four articles were finalized from an initial 2905 articles found via searches on the Annals of Internal Medicine by American College of Physicians(ACP)^(TM),BioMed Central(BMC)^(TM),BMJ Journals^(TM),Journal of the American Medical Association(JAMA)^(TM),PubMed^(TM),SAGE^(TM),ScienceDirect^(TM),SpringerLink(e-journals)^(TM),taylor and Francis Online^(TM),and Wiley Online Library^(TM) ***:Recognized structural frameworks for scoping reviews were utilized to guide the methodology and technical aspects of this *** extraction was conducted via a charting ***:Research gaps identified include a paucity in research on the subject of obesity and breast cancer among elderly women;there is a limitation of the types of methodologies used in the research on this subject indicating vast opportunities for future studies using different methodologies;lack of use of the alternative types of physical activity and exercise such as Tai Chi,Qigong and Yoga;lack of focus on the older elderly population;and areas of social support from family and friends for obese elderly with breast cancer to engage in physical activity and ***:Future research would address the urgent need within academia to address the research gap of PAE and *** research should use a diverse range of both quantitative and qualitative research methodologies,while including eastern exercise regimens such as Tai Chi,Qigong and Yoga as a means of studying PAE among ***,future research may focus on the“old elderly”as a demographic group of study as well as how social suppo

关键词： Obesity Breast cancer Elderly Physical activity Exercise

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Al_3Zr和Al_3Nb作为铝合金晶粒细化剂的晶体学研究(英文)

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Transactions of Nonferrous Metals Society of China 2014年第7期24卷 2034-2040页

作者：汪锋邱冬刘峙麟 John taylor mark EASTON 张明星 School of Mechanical and Mining Engineering The University of Queensland School of Physics and Materials Engineering Monash University

利用edge-to-edge matching模型从晶体学角度研究Al3Zr和Al3Nb两种金属间化合物作为铝合金晶粒细化剂的有效性。结果表明,Al3Zr和Al3Nb两种金属间化合物和铝之间的原子间距错配和面间距错配值都很小。此外,模型预测Al3Zr和Al3Nb两种金... 详细信息

利用edge-to-edge matching模型从晶体学角度研究Al3Zr和Al3Nb两种金属间化合物作为铝合金晶粒细化剂的有效性。结果表明,Al3Zr和Al3Nb两种金属间化合物和铝之间的原子间距错配和面间距错配值都很小。此外,模型预测Al3Zr和Al3Nb两种金属间化合物与铝之间存在良好的晶粒取向关系。根据模型理论可以从晶体学角度证明这两种金属间化合物对铝合金是有效的晶粒异质形核细化剂。本晶体学研究为包晶铝合金Al-Zr和Al-Nb中出现的明显晶粒细化现象提供了合理解释,同时为理解晶粒细化机理提供了新方法。

关键词：铝合金 Al3Zr Al3Nb 晶粒细化包晶晶体学 E2EM模型

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New Partnerships for Co-delivery of the 2030 Agenda for Sustainable Development

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International Journal of Disaster Risk Science 2020年第5期11卷 680-685页

作者： Adrian Bucher Andrew Collins Ben Heaven taylor David Pan Emma Visman James Norris Joel CGill John Rees mark Felling Marta Tufet Bayona Sonia Cassidy Virginia Murray UK Collaborative on Development Research London NW12BEUK Disaster and Development Network(DDN) Department of Geography and Environmental SciencesNorthumbria UniversityNewcastle-upon-Tyne NE18STUK Evidence Aid AbingdonOxfordshire OX135DBUK Global Health Medical Research Council SwindonSwindon SN21FLUK Department of Geography King's College LondonLondon WC2B 4BGUK VNG Consulting Limited Kent TN248DHUK Ordnance Survey Southampton SO16 OASUK Global Geoscience British Geological SurveyKeyworth NG125GGUK Earth Hazards and Observatories British Geological SurveyNottingham NG123ENUK ALLFED LondonUK Global Disaster Risk Reduction Public Health EnglandLondon SE18UGUK

Partnerships have become a comer stone of contemporary research that recognizes working across disciplines and co-production with intended users as essential to enabling sustainable ***,research that addresses sustainable development challenges brings an urgent need to reflect on the ways that partnerships are supported,and for the disaster risk management and resilience communities,efforts to support realization of the wider 2030 Agenda for sustainable development bring particular *** November 2019,the UK Disasters Research Group(DRG)brought together a number of key stakeholders focused on disaster risk,resilience,and sustainability research relevant to Official DevelopmeAssistance to consider how fit for purpose existing partnership models are for the pace of change required to deliver the priorities of the wider 2030 *** were invited to discuss how research partnerships across three levels(individual and project-based;national and institutional;and international)could be improved based on elements that facilitate robust partnerships and learning from aspects that hinder *** the discussions,participanls emphasized the importance of effective communication mechanisms in building partnerships,co-designing projects,and establishing shared *** approaches to addressing equitable partnerships and funding more substantive timelines will be key to responding to the challenges of the 2030 Agenda.

关键词： 2030 Agenda for sustainable development Disaster risk reduction DRG Inter national development Partnerships Research fun ding

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