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Ketamine and midazolam sedation for pediatric gastrointestinal endoscopy in the Arab world

World Journal of Gastroenterology 2011年第31期17卷 3630-3635页

作者： Mohamad-Iqbal S Miqdady Wail A Hayajneh Ruba Abdelhadi mark a gilger Pediatric Department Medical SchoolJordan University of Science and Technology Pediatric Institute Sheikh Khalifa Medical Citymanaged by Cleveland ClinicAbu Dhabi Pediatric Department University of Texas Health Science CenterSan AntoniaTXSan Antonia Pediatric Department Baylor College of Medicine

AIM:To evaluate the safety and effectiveness of intravenous ketamine-midazolam sedation during pediatric endoscopy in the Arab ***:A retrospective cohort study of all pediatric endoscopic procedures performed between 2002-2008 at the shared endoscopy suite of King Abdullah University Hospital,Jordan University of Science & Technology,Jordan was *** children were > 1 year old and weighed > 10 kg with American Society of Anesthesiologists class 1 or *** was performed in terms of sedation-related complications(desaturation,respiratory distress,apnea,bradycar-dia,cardiac arrest,emergence reactions),adequacy of sedation,need for sedation reversal,or failure to complete the ***:A total of 301 patients(including 160 males) with a mean age of 9.26 years(range,1-18 years) were *** were premedicated with atropine;and 79.4%(239/301) had effective and uneventful *** 248(82.4%) of the 301 patients received a mean dose of 0.16 mg/kg(range,0.07-0.39) midazolam and 1.06 mg/kg(range,0.31-2.67) ketamine,respectively within the recommended dosage *** maximum midazolam dose was exceeded in 17.6% patients [34 female(F):19 male(M),P = 0.003] and ketamine in 2.7%(3 M:5 F).Maximum midazolam dose was more likely to be exceeded than ketamine(P 1 year and weighing > 10 kg without co-morbidities.

关键词： Pediatric endoscopy Sedation Ketamine Arab

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Endoscopic retrograde cholangiography for pediatric choledocholithiasis: Assessing the need for endoscopic intervention

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World Journal of Gastrointestinal Endoscopy 2016年第11期8卷 425-432页

作者： Douglas S Fishman Bruno P Chumpitazi Isaac Raijman Cynthia Man-Wai Tsai E O’Brian Smith mark V Mazziotti mark a gilger Section of Pediatric Gastroenterology Hepatology and Nutrition Baylor College of Medicine Texas Children’s Hospital Houston TX 77030 United States Digestive Associates of Houston Houston TX 77098 United States Department of Surgery Section of Pediatric Surgery Baylor College of Medicine Houston TX 77030 United States Department of Surgery Section of Pediatric Surgery Baylor College of MedicineHouston TX 77030 United States Department of Pediatrics Baylor College of Medicine Children’s Hospital of San Antonio San Antonio TX 78207 United States

AIM:To assess pediatric patients for *** applied current adult guidelines to identify predictivefactors in ***:A single-center retrospective analysis was performed at a tertiary children's *** evaluated 44 consecutive pediatric patients who underwent endoscopic retrograde cholangiography(ERCP) for suspected *** were stratified into those with common bile duct stones(CBDS) at ERCP vs those that did not using the American Society of Gastrointestinal Endoscopy(ASGE) guidelines(Very Strong and Strong criteria) for suspected ***:CBDS were identified in 84% at the time of *** ultrasound identified CBDS in 36% of *** bilirubin ≥ 0.5 mg/d L was an independent risk factor for CBDS(P = 0.003).The Very Strong(59.5%) and Strong(48.6%) ASGE criteria identified the majority of patients(P = 0.0001).A modified score using conjugated bilirubin had a higher sensitivity(81.2% vs 59.5%) and more likely to identify a stone than the standard criteria,odds ratio of 25.7 compared to *** aminotransferase and gamma-glutamyl transferase values identified significant differences in a subset of patients with odds ratio of 4.1 and 3.25,***:Current adult guidelines identified the majority of pediatric patients with CBDS,but specific pediatric guidelines may improve detection,thus decreasing risks and unnecessary procedures.

关键词： Endoscopic retrograde cholangiography Pediatric Endoscopy Choledocholithiasis Children Gallstones Abdominal ultrasound

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