检索结果-南通市图书馆

The role of L-arginine metabolism in neurocritical care patients

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第7期17卷 1446-1453页

作者： marius Marc-Daniel Mader Patrick Czorlich Department of Neurosurgery University Medical Center Hamburg-EppendorfHamburgGermany Institute for Stem Cell Biology and Regenerative Medicine Stanford University School of MedicineStanfordCAUSA

Nitric oxide is an important mediator of vascular autoregulation and is involved in pathophysiological changes after acute neurological *** oxide is generated by nitric oxide synthases from the amino acid L-arginine.L-arginine can also serve as a substrate for arginases or lead to the generation of dimethylarginines,asymmetric dimethylarginine,and symmetric dimethylarginine,by *** dimethylarginine is an endogenous inhibitor of nitric oxide synthase and can lead to endothelial *** review discusses the role of L-arginine metabolism in patients suffering from acute and critical neurological disorders often requiring neuro-intensive care *** addressed in this review include intracerebral hemorrhage,aneurysmal subarachnoid hemorrhage,and traumatic brain *** therapeutic advances in the field are described including current randomized controlled trials for traumatic brain injuries and hemorrhagic stroke.

关键词： arginine brain injuries,traumatic cerebral hemorrhage dimethylarginine nitric oxide stroke subarachnoid hemorrhage

Swelling-Based Chemical Sensing With Unmodified Optical Fibers

在线全文

学校读者我要写书评

暂无评论

Photonic Sensors 2022年第2期12卷 99-104页

作者： Alin JDERU Dorel DOROBANTU Dominik ZIEGLER marius ENACHESCU S.C.NanoPro START MC S.R.L. Bucharest 033091Romania Center for Surface Science and Nanotechnology University Politehnica of BucharestBucharest 060042Romania Academy of Romanian Scientists Bucharest 050094Romania

We use distributed fiber optic strain sensing to examine swelling of the fiber’s polymer *** distributed sensing technique that uses unmodified low-cost telecom fibers opens a new dimension of applications that include leak detection,monitoring of water quality,and waste *** a short-range length scale,the technology enables“lab-on-a-fiber”applications for food processing,medicine,and biosensing for *** chemical sensing is realized with unmodified low-cost telecom optical fibers,namely,by using swelling in the coating material of the fiber to detect specific *** generic and able to work in various areas such as environmental monitoring,food analysis,agriculture or security,the proposed chemical sensors can be targeted for water quality monitoring,or medical diagnostics where they present the most groundbreaking ***,the technique is without restrictions applicable to longer range installations.

关键词： Chemical sensing distributed fiber optic strain short range sensing Brillouin optical time domain analysis

First thrust measurements in ionic multi-propeller rotational engines

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Propulsion and Power Research 2023年第1期12卷 44-58页

作者： Adrian Ieta marius Chirita Electrical and Computer Engineering Department SUNY OswegoOswegoNY 13126-3599USA Applied Physics/Condensed Matter Department National Institute for Research and Development in Electrochemistry and Condensed MatterTimisoaraRO-300224Romania

Rotary ionic engines(RIEs)with multi-coaxial contra-rotating propellers(12.6 cm diameter)and their axial thrust are investigated in laboratory conditions,in air at atmospheric pressure,for the first *** goal is to evaluate more advantageous configurations that may be scaled up and further help with development of rotary ionic *** propellers are designed with regular pin-emitter electrodes placed coaxially inside a cylindrical collector *** high voltage is applied,propellers spin generating conventional axial thrust which is measured with an electronic scale in a“see-saw”*** to 40 mN thrust was obtained in single propeller RIE at 2600 rpm,0.34 mA,37.5 kV,and an optimal collector electrode diameter of 17 *** thrust can be obtained with two and three propellers at constant current per propeller but at a decreased *** the axial propeller-separation showed that propeller-interaction is minimal above 5 ***-to-power and thrust-tocurrent ratios were calculated and *** experimentally confirm here for the first time that within certain limits,the thrust-to-power variation can be assessed by the propeller kinetic energy-to-power ratio and also by the impedance of the gap(voltage-to-current ratio).A comparison of RIE arrays performance with one,two,and three coaxial propellers and the same total number of propellers per array(six)is also *** arrays with multi-coaxial propellers can provide larger thrust densities than single-propeller ***,arrays employing two coaxial propeller unit may be more weight effective.

关键词： Ionic wind EHD pump Electrohydrodynamics Corona discharge Thrust-to-power Propeller Ion propulsion Plasma thrusters Electroaerodynamic thrusters Ionocraft

Measurements of Laminar Burning Velocities of Alternative Fuels:Application in Transport and Aerospace

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2023年第2期32卷 503-512页

作者： RICHTER Sandra braun-UNKHOFF Marina NAUMANN Clemens German Aerospace Center(DLR) Institute of Combustion TechnologyDepartment of Chemical Kinetics and AnalyticsStuttgart 70569Germany

The laminar burning velocity belongs to the fundamental combustion properties of fuels being a measure for their heat release,flame length,as well as reactivity and combustion stability,and thus,may impact the design of burners and combustion ***,these experimental data are needed for the validation and optimization within the construction and development of detailed chemical kinetic reaction *** this study,an overview of the different applications of fuel characterization regarding the specific area of interest(road transport,aviation,and aerospace)will be *** on the application,effects of different molecular characteristics on the laminar burning velocity are evaluated:the presence of oxygen atoms and the grade of branching in a specific fuel molecule as well as the difference in the type of a chemical bond,here,single and double *** of alternative fuels being discussed in the present study are:(Ⅰ)oxymethylene ether(OMEn)in the field of road transport;(Ⅱ)a paraffinic Alcohol-to-Jet fuel as sustainable aviation fuel;and(Ⅲ)mixtures of ethane or ethene with nitrous oxide as green propellants for rocket propulsion applications.

关键词： laminar burning velocity alternative sustainable fuels road transport aviation fuels green propellants

The transcriptomic signature of responses to larval crowding in Drosophila melanogaster

在线全文

学校读者我要写书评

暂无评论

Insect Science 2023年第2期30卷 539-554页

作者： Juliano Morimoto marius Wenzel Davina Derous Youn Henry Herve Colinet School of Biological Sciences University of AberdeenAberdeenUnited Kingdom Programa de Pos-graduacao em Ecologia e Conservacao Universidade Federal do ParanaCuritibaBrazil Institute of Mathematics King's CollegeUniversity of AberdeenAberdeenUnited Kingdom CNRS ECOBIO(Ecosystemesbiodiversiteévolution)—UMR 6553University of RennesRennesFrance Department of Ecology and Evolution University of LausanneLausanneSwitzerland

Intraspecific competition at the larval stage is an important ecological factor affecting life-history,adaptation and evolutionary trajectory in holometabolous ***,the molecular pathways underpinning these ecological processes are poorly *** reared Drosophila melanogaster at three egg densities(5,60,and 300 eggs/mL)and sequenced the transcriptomes of pooled third-instar *** also examined emergence time,egg-to-adult viability,adult mass,and adult sex-ratio at each *** crowding had minor detrimental effects on adult phenotypes compared to low density and yielded 24 differentially expressed genes(DEGs),including several chitinase *** contrast,high crowding had substantial detrimental effects on adult phenotypes and yielded 2107 *** these,upregulated gene sets were enriched in sugar,steroid and amino acid metabolism as well as DNA replication pathways,whereas downregulated gene sets were enriched in ABC transporters,taurine,Toll/Imd signaling,and P450 xenobiotics metabolism ***,our findings show that larval crowding has a large consistent effect on several molecular pathways(i.e.,core responses)with few pathways displaying density-specific regulation(i.e.,idiosyncratic responses).This provides important insights into how holometabolous insects respond to intraspecific competition during development.

关键词： intraspecific competition larval crowding life-history trade-offs transcriptomics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

叽叭喳喳直播间

小哥白尼（野生动物） 2024年第5期 17-17页

作者： Iris braun(图) 不详

一大拨弹幕正在向你袭来……再说一遍!别去招惹狮子!(微信每每)都给我闭嘴,写作业去!(微信馨)妈妈,你别怪弟弟,如果要罚就罚我吧!

关键词：微信直播间写作业

A small,polyphyletic group of Firmicutes synthesizes trimethylamine from L-carnitine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

mLife 2023年第3期2卷 267-271页

作者： marius Vital Ylenia Heinrich-Sanchez Hannover Medical School Institute for Medical Microbiology and Hospital EpidemiologyHannoverGermany

Impact statement Gut microbiota-derived trimethylamine(TMA)is associated with cardiometabolic disorders and exemplifies a microbial involvement in the etiology of emerging,noncommunicable diseases,the leading causes of death *** bio-chemical pathways taking dietary compounds as intake have been described with distinct taxa involved that are all present at low relative abundances.A recently discovered pathway is now considered to be the main route for TMA synthesis from L-carnitine involvingγ-butyrobetaine as an intermediate *** comprehensive(meta)genomic screening of publicly available data,namely,genomes of the UHGG catalog(n>200,000)and 10 metagenomic(transcriptomic)data sets,we revealed bacteria synthesizing TMA via this pathway and specified their *** will contribute to stratification of individuals based on their gut microbiota's potential to synthesize TMA and might aid in the development of strategies restricting TMA formation.

关键词： product. synthesize statement

Testing the robustness of particle-based separation models for the magnetic separation of a complex skarn ore

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Mining Science and Technology 2022年第3期32卷 645-655页

作者： Lucas Pereira Max Frenzel Markus Buchmann marius Kern Raimon Tolosana-Delgado K.Gerald van den Boogaart Jens Gutzmer Hemholtz-Zentrum Dresden-Rossendorf Helmholtz Institute Freiberg for Resource Technology09599 FreibergGermany German Aerospace Center Institute of Low-Carbon Industrial Processes03046 CottbusGermany TU Bergakademie Freiberg Institute for Stochastics09599 FreibergGermany

Physical separation processes are best understood in terms of the behaviour of individual ore ***,while different empirical particle-based separation modelling approaches have been developed,their predictive performance has never been tested under variable process ***,we investigated the predictive performance of a state-of-the-art particle-based separation model under variable feed composition for a laboratory-scale magnetic separation of a skarn *** scenarios were investigated:one in which the mass flow of the different processing streams could be measured and one in which it had to be estimated from *** both scenarios,the predictive models were sufficiently general to predict the process outcomes of new samples of variable ***,the scenario in which mass flow could be measured was4%more precise in predicting mass *** process behaviour of minerals present at concentrations above 0.1%by weight could be accurately *** findings indicate the potential use of this method to minimize the costs of metallurgical testwork while providing in-depth understanding of the recovery behaviour of individual ore ***,the method may be used to establish powerful tools to forecast mineral recoveries for partly new ore types at a running mining operation.

关键词： Metallurgical tests Particle-based separation modelling Magnetic separation Cassiterite recovery

Approximating multi-purpose AC Optimal Power Flow with reinforcement trained Artificial Neural Network

在线全文

学校读者我要写书评

暂无评论

能源与人工智能(英文) 2022年第1期7卷 131-141页

作者： Zhenqi Wang Jan-Hendrik Menke Florian Schäfer Martin braun Alexander Scheidler Department of Energy Management and Power System Operation University of KasselWilhelmshöher Allee 7334121 KasselGermany Fraunhofer Institute for Energy Economics and Energy System Technology Königstor 5934119 KasselGermany

Solving AC-Optimal Power Flow(OPF)problems is an essential task for grid operators to keep the power system safe for the use cases such as minimization of total generation cost or minimization of infeed curtailment from renewable DERs(Distributed Energy Resource).Mathematical solvers are often able to solve the AC-OPF problem but need significant computation *** neural networks(ANN)have a good application in function approximation with outstanding computational *** this paper,we employ ANN to approximate the solution of AC-OPF for multiple *** novelty of our work is a new training method based on the reinforcement learning concept.A high-performance batched power flow solver is used as the physical environment for training,which evaluates an augmented loss function and the numerical action *** augmented loss function consists of the objective term for each use case and the penalty term for constraints *** training method enables training without a reference OPF and the integration of discrete decision variable such as discrete transformer tap changer position in the constrained *** improve the optimality of the approximation,we further combine the reinforcement training approach with supervised training labeled by reference *** benchmark results show the high approximation quality of our proposed approach while achieving high computational efficiency on multiple use cases.

关键词： OPF Artificial neural network Reinforcement learning Grid planning and operation Grid congestion management