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基于网络化的国际合作培训对提高精神科护士核心能力的效果

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上海交通大学学报（医学版） 2015年第8期35卷 1213-1216页

作者：施忠英张曙映高麒孔庆芳 maritta valimaki 上海交通大学医学院附属精神卫生中心上海200030 同济大学护理学院上海200092 Department of Nursing Science University of TurkuTurun yliopisto 20014

目的探讨基于网络化的国际合作培训对提高精神科护士核心能力的效果。方法于2013年6月—10月对实验组67名护士和对照组56名护士开展以巩固和提高精神科护士核心能力为目标的培训课程。课程为上海交通大学医学院附属精神卫生中心护理部... 详细信息

目的探讨基于网络化的国际合作培训对提高精神科护士核心能力的效果。方法于2013年6月—10月对实验组67名护士和对照组56名护士开展以巩固和提高精神科护士核心能力为目标的培训课程。课程为上海交通大学医学院附属精神卫生中心护理部与芬兰图尔库大学护理学院合作,采用网络化学习的形式。在实施医院常规业务培训的基础上,对实验组进行为期5个月的网络课程培训。应用注册护士核心能力量表(CIRN)分别在干预前后进行评定。结果实验组CIRN总分和各因子值(除专业发展)培训前后自身比较差异有统计学意义(P<0.01);培训后实验组CIRN总分和各因子值(除临床护理和专业发展)与对照组比较差异有统计学意义(P<0.05)。结论基于网络化学习的国际合作培训对提高精神科护士核心能力具有良好的效果,有助于精神科护理继续教育领域国际间的合作与交流。

关键词：网络化学习核心能力精神科护士

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The feelings and thoughts of mental health nurses concerning the management of distressed and disturbed in-patients: A comparative qualitative European study

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Open Journal of Nursing 2013年第6期3卷 426-436页

作者： Vida Staniuliene Mary Chambers Xenya Kantaris Raija Kontio Lauri Kuosmanen Anne Scott Maria Antonia Rebelo Botelho Renzo Zanotti maritta valimaki Faculty of Health Sciences Klaipėda State CollegeKlaipedaLithuania Faculty of Health Social Care and EducationKingston University and St.George’sUniversity of LondonLondonUK Department of Nursing Science University of Turku and Hospital District of Helsinki and UusimaaTuusulaFinland Department of Nursing Science University of TurkuTurkuFinland Dublin City University DublinIreland Nursing Research and Development Unit Escola Superior de Enfermagem de LisboaCoimbraPortugal Department of Molecular Medicine University of PadovaPaduaItaly Department of Nursing Science University of Turku and Hospital District of Southwest FinlandTurkuFinland

High levels of distress and disturbance amongst those experiencing acute mental illness can be a major problem for mental health nurses. The feelings experienced by these nurses when caring for and supporting disturbed and/or distressed patients along with their concurrent thoughts are not well described in the literature. To date, this complex issue has not been explored within a comparative European context. The objective of this qualitative study was to explore the feelings and thoughts of mental health nurses when supporting and caring for distressed and/or disturbed patients in 6 European countries. Methods: Focus groups were used to collect data from 130 mental health nurses working in acute inpatient psychiatric settings. Results: Data were analysed using content analysis. Findings highlighted 6 broad themes: 1) Mixed emotions: expressive and responsive, 2) Procedure for caring for and supporting disturbed and/or distressed patients, 3) Use of guidelines for caring and supporting disturbed and/or distressed patients, 4) Team and organisational support, 5) Ethical concerns: Cognitive dissonance and 6) Education and training. Commonalities and differences were?found across all themes. Approaches to care, nurses’ role and education, clinical guidelines and/or standards vary from country to country, therefore the care, treatment and management of distressed and/or disturbed patients are various. As a result, mental health nurses have different experiences, various emotional quandaries concurrent with cognitive dissonance and different coping strategies when caring for and supporting distressed and disturbed patients. Conclusions: More emphasis needs to be given to the emotional quandaries and concurrent cognitive dissonance experienced by mental health nurses caring for distressed and/or disturbed inpatients in acute psychiatric settings. Increased access to education and training with particular attention to interpersonal communication and relationship building

关键词： Acute Inpatient Psychiatric Settings Cognitive Dissonance Coercive Interventions Feelings Mental Health Nurse Thoughts

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我国护理网络课程的发展现状

护理研究（中旬版） 2014年第11期28卷 3973-3975页

作者：孔庆芳施忠英 maritta valimaki 胡珏上海交通大学医学院附属精神卫生中心 200030 Department of Nursing Science University of Turku Finland 20014

从国家精品课程资源网对护理网络精品课程的呈现及应用情况进行分析,结合文献对护理网络课程的开发与设计的分析得出,我国护理网络课程发展起步晚但发展迅速,但存在护理网络课程的资源分布不均、护理网络课程资源重复性差并缺乏共享性... 详细信息

从国家精品课程资源网对护理网络精品课程的呈现及应用情况进行分析,结合文献对护理网络课程的开发与设计的分析得出,我国护理网络课程发展起步晚但发展迅速,但存在护理网络课程的资源分布不均、护理网络课程资源重复性差并缺乏共享性、护理网络课程开发与设计的研究较少、课程内容表现形式过于简单且资源不足、课程评价体系过于机械化。建议:护理网络课程应从学习者的实际需要出发,增加智能反馈系统,增加互动交流,实现资源共享,不断更新、完善护理网络课程。

关键词：护理网络课程发展

中芬精神卫生循证护理研究生交换课程培训方案与启示

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护理管理杂志 2016年第11期16卷 805-806页

作者：黄蓉徐磊李觉张曙映 maritta valimaki 同济大学附属第一妇婴保健院妇科上海市201204 同济大学医学院上海市200092 芬兰图尔库大学护理学院图尔库市20014

文章介绍中国同济大学医学院护理系与芬兰图尔库大学护理学院联合开展"循证护理-精神卫生"护理单元的教育改革项目培训方案,包括组建交换课程培训师资、确立课程主题、明确课程目标、丰富教学模式与方法及细化教学内容。提示研究生循证... 详细信息

文章介绍中国同济大学医学院护理系与芬兰图尔库大学护理学院联合开展"循证护理-精神卫生"护理单元的教育改革项目培训方案,包括组建交换课程培训师资、确立课程主题、明确课程目标、丰富教学模式与方法及细化教学内容。提示研究生循证护理教学过程中,倡导院校与医院合作教学以促进资源共享;尊重患者意愿以倡导"患者参与"文化;通过国际交流以提高跨文化护理能力,有助于双方研究生深入理解彼此在精神卫生循证护理实践中存在的问题,也为国内循证护理教学提供参考。

关键词：国际合作研究生精神卫生循证护理

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Involvement of CYP347W1 in neurotoxin 3-nitropropionic acid-based chemical defense in mustard leaf beetle Phaedon cochleariae

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Insect Science 2022年第2期29卷 453-466页

作者： Nanxia Fu Tobias Becker Wolfgang Brandt maritta Kunert Antje Burse Wilhelm Boland Department of Bioorganic Chemistry Max Planck Institute for Chemical EcologyJenaGermany Key Laboratory of Tea Biology and Resource Utilization Tea Research InstituteChinese Academy of Agricultural SciencesHangzhouChina Department of Bioorganic Chemistry Leibniz Institute of Plant BiochemistryHalle(Saale)Germany Department of Natural Product Biosynthesis Max Planck Institute for Chemical EcologyJenaGermany Department of Medical Technology and Biotechnology Ernst Abbe Hochschule JenaJenaGermany

Chrysomelina beetlesstore 3-nitropropionic acid in form of a pretoxin,isoxazolin-5-one glucoside-conjugated ester,to protect themselves against *** we identified a cytochrome P450 monooxygenase,CYP347W1,to be involved in the production of the 3-nitropropionic acid moiety of the isoxazolin-5-one glucoside *** down CYP347W1 led to a significant depletion in the concentration of the isoxazolin-5-one glucoside ester and an increase in the concentration of the isoxazolin-5-one glucoside in the larval *** assays with the heterologously expressed CYP347W1 showed freeβ-alanine was not the direct *** modeling indicated thatβ-alanine-CoA ester can fit into CYP347W1’s active ***,we proved that Phaedon cochleariae eggs are not able to de novo synthesize 3-NPA,although both isoxazolin-5-one glucoside and its 3-NPA-conjugated ester are present in the *** results provide direct evidence for the involvement of CYP347W1 in the biosynthesis of a *** chemical defense compound.

关键词： chemical defense isoxazolin-5-one glucoside isoxazolin-5-one glucoside ester leaf beetles P450 3-nitropropionic acid(3-NPA)

Impact of urbanization on plant diversity: A case study in built-up areas of Beijing

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Forestry Studies in China 2008年第3期10卷 179-188页

作者： LIANG Yao-qin LI Jing-wen LI Jing Sanna Katrina valimaki Key Laboratory for Silviculture and Conservation of Ministry of Education Beijing Forestry University Beijing 100083 P. R. China School of Environmental and Urban Studies Shenzhen Graduate School Peking University Shenzhen 518055 E R. China Department of Forest Ecology University of Helsinki Helsinki FI-00014 Finland

Urbanization is developing rapidly in the world, which seriously changes the habitat of organisms and has clearly a negative effect on biodiversity. Preservation of biodiversity is crucial in urban planning and management, which is also an important symbol for the level of greening. Problems such as scarcity of urban green space and plant species have become obstacles to the establishment of ecological friendly cities. However, coexistence of nature and modernization, as well the coordination of economic development and biodiversity, are goals that people are seeking. We have taken the builtup areas of Beijing as a study case and discussed the impacts of urbanization on plant diversity, with the support of fieldwork and SPOT remote sensing data. The results are as follows： 1） in the process of urbanization, exotic plants have been widely introduced, which has affected species composition and the proportion of native plants; it is clear that artificial green spaces always will have a lower level of plant diversity than natural green spaces; 2） functional differences of green space types partially decide their species abundance, so that plant diversity in greenbelts and streets is generally lower than in parks; 3） the spatial variety of plant diversity contributes much to the imbalance of district de- velopment and the planning of different functional zones; this variation is embodied in different ring-belts and directions; 4） habitat fragmentation also affects plant diversity to a great extent; there is a significant positive correlation between high fragmentation and low plant diversity. According our results, some suggestions are proposed, which would be suitable for the preservation of plant di- versity and ecological improvement during urbanization.

关键词： urbanization plant species diversity landscape fragmentation

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Steroidal scaffold decorations in Solanum alkaloid biosynthesis

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Molecular Plant 2024年第8期17卷 1236-1254页

作者： Rosalind Lucier Mohamed O.Kamileen Yoko Nakamura Sofiia Serediuk Ranjit Barbole Jens Wurlitzer maritta Kunert Sarah Heinicke Sarah E.O'Connor Prashant D.Sonawane Department of Natural Product Biosynthesis Max Planck Institute for Chemical Ecology07745 JenaGermany Research Group Biosynthesis and NMR Max Planck Institute for Chemical Ecology07745 JenaGermany Biochemical Sciences Division CSIR-National Chemical LaboratoryPune 411008MaharashtraIndia

Steroidal glycoalkaloids(SGAs)are specialized metabolites produced by hundreds of Solanum species,including important vegetable crops such as tomato,potato,and *** it has been known that SGAs play important roles in defense in plants and“anti-nutritional"effects(e.g.,toxicity and bitterness)to humans,many of these molecules have documented anti-cancer,anti-microbial,antiinflammatory,anti-viral,and anti-pyretic *** these,α-solasonine andα-solamargine isolated from black nightshade(Solanum nigrum)are reported to have potent anti-tumor,anti-proliferative,and anti-inflammatory ***,α-solasonine andα-solamargine,along with the core steroidal aglycone solasodine,are the most widespread SGAs produced among the Solanum ***,it is still unknown how plants synthesize these bioactive steroidal *** comparative metabolomictranscriptome-guided approach,biosynthetic logic,combinatorial expression in Nicotiana benthamiana,and functional recombinant enzyme assays,here we report the discovery of 12 enzymes from *** that converts the starting cholesterol precursorto solasodine aglycone,and the downstreamα-solasonine,α-solamargine,and malonyl-solamargine SGA *** further identified six enzymes from cultivated eggplant that catalyze the production ofα-solasonine,α-solamargine,and malonyl-solamargine SGAs from solasodine aglycone via glycosylation and atypical malonylation *** work provides the gene tool box and platform for engineering the production of high-value,steroidal bioactive molecules inheterologoushosts usingsyntheticbiology.

关键词： steroidal glycoalkaloids Solanum biosynthetic pathway α-solamargine malonyl-solamargine specialized metabolites

Mesothelioma in relation to asbestos exposure in laboratory work

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Health 2013年第6期5卷 981-984页

作者： Penpatra Sripaiboonkij maritta S. Jaakkola Center for Environmental and Respiratory Health Research University of Oulu Oulu Finland Faculty of Public Health Thammasat University Bangkok Thailand

Introduction: Mesothelioma is a malignant conditioncaused by exposure to asbestos that has typically a long latency period. The disease is usually found in the later stages when the prognosis is poor despite treatments. Objective: To report a mesothelioma found in a laboratory. Method: We reported here a case of a 60 year-old-man who was exposed to asbestos fibres-first when he studied in a laboratory at high school and then he had exposure over the following years until graduating with a master’s degree, but he did not have exposure after it. He was a smoker as a teenager and he gave up after 23 years. His first symptom was coughing at night which lasted for several months until the pleural fluid was discovered on the right side of thorax. This triggered investigations led to a diagnosis of mesothelioma. According to a systematic literature search, mesothelioma has not been reported previously in relation to asbestos exposure in laboratory work. An operation was carried out, but the patient refused to take chemotherapy due to the limited benefits that could be expected from it. Instead, he opted for a Budwig protocol. The case has had a good quality of life since the surgery, and did not have any medications. He has regular check-ups at the hospital. Conclusion: Our study has shown that mesothelioma is not only a risk to people directly exposed to asbestos, but also indirectly from, for example, laboratory work. People should avoid exposure to asbestos in daily life.

关键词： Mesothelioma Asbestos Occupational Diseases Laboratory Budwig

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我国护理网络课程的发展现状

护理研究 2014年第32期 3973-3975页

作者：孔庆芳施忠英 maritta Vlimki 胡珏上海交通大学医学院附属精神卫生中心 Department of Nursing Science University of Turku Finland

关键词：护理网络课程发展