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Surgical Correction of Tetralogy of Fallot in Adulthood

Open Journal of Thoracic Surgery 2012年第3期2卷 72-77页

作者： Ignacio Lugones Pablo D. Inguanzo diego Antoni marisa di santo Rubén O. García 2Department of Pediatric Cardiology Hospital Universitario Fundación Favaloro Buenos Aires Argentina Department of Pediatric Cardiology Hospital Universitario Fundación Favaloro Buenos Aires Argentina Pediatric Cardiovascular Surgery Unit Hospital Universitario Fundación Favaloro Buenos Aires Argentina

Background: The aim of this study is to evaluate the short-term results of surgical correction of Tetralogy of Fallot in adult patients. Methods: Between 1999 and 2007, surgical correction was performed in 16 adult patients (mean age: 34.6 years;range: 18 to 62). Five previous procedures had been performed in 4 patients. Thirteen patients were in NYHA functional classification III or IV (81%), and 12 were cyanotic. Echocardiography was performed in all patients and 14 of them were catheterized. The mean gradient in the right ventricular outflow tract was 82 mmHg. Four patients had bad anatomy, consisting in coronary fistulas (2) and small pulmonary artery branches (2). Results: Infundibular resection was performed in all patients, ventricular septal defect closure in 15, pulmonary valve commissurotomy in 8, right ventricular outflow tract patch enlargement in 9 and transannular patch placement in 4. Three patients died during the postoperative hospital stay, 2 of them with sepsis. All of them had bad anatomy and severe preoperative condition. No residual defects were found. The other 13 patients had a good recovery. Eleven had less than 24 hours of mechanical ventilation. Early hospital discharge was possible in all survivors. Conclusion: Surgical correction of Tetralogy of Fallot in adulthood is an infrequent procedure. The short-term results depend mostly on the anatomic substrate and the preoperative clinical condition of the patient.

关键词： Adult Congenital Heart disease Congenital Heart Surgery Postoperative Care Pulmonary Arteries

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A chaotic hierarchical encryption/watermark embedding scheme for multi-medical images based on row-column confusion and closed-loop bi-directional diffusion

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Chinese Physics B 2024年第2期33卷 228-237页

作者：张哲祎牟俊 santo Banerjee 曹颖鸿 School of Information Science and Engineering Dalian Polytechnic UniversityDalian 116034China Department of Mathematical Sciences Politecnico di TorinoTorino 10129Italy

Security during remote transmission has been an important concern for researchers in recent *** this paper,a hierarchical encryption multi-image encryption scheme for people with different security levels is designed,and a multiimage encryption(MIE)algorithm with row and column confusion and closed-loop bi-directional diffusion is adopted in the *** ensuring secure communication of medical image information,people with different security levels have different levels of decryption keys,and differentiated visual effects can be obtained by using the strong sensitivity of chaotic *** highest security level can obtain decrypted images without watermarks,and at the same time,patient information and copyright attribution can be verified by obtaining watermark *** experimental results show that the scheme is sufficiently secure as an MIE scheme with visualized differences and the encryption and decryption efficiency is significantly improved compared to other works.

关键词： chaotic hierarchical encryption multi-medical image encryption differentiated visual effects row-column confusion closed-loop bi-directional diffusion transform domain watermark embedding

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Surgical Correction of Tetralogy of Fallot in Adulthood

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Open Journal of Thoracic Surgery（胸外科期刊） 2012年第3期

作者： Ignacio Lugones Pablo D. Inguanzo diego Antoni marisa di santo Rubén O. García

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Current Topics in Acute Abdomen: Causes, diagnostics, and Emerging Therapies

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Journal of Biosciences and Medicines 2024年第5期12卷 171-177页

作者： Lucas de Oliveira Varca Maria Carolina de Almeida santo Department of Medicine Universidade do Oeste Paulista Guaruj&#225 Brazil

Acute abdomen is a serious clinical condition that requires immediate attention due to its association with intense pain and rapid progression. This article reviews important aspects of the causes, diagnostics, and treatments of acute abdomen. The research highlights the diversity of etiologies, ranging from the most common, such as acute appendicitis, to the less frequent, such as intestinal perforations by foreign bodies. Complex diagnostic methods, including clinical examinations and imaging such as computed tomography, are essential to guide accurate diagnosis, given the overlap of symptoms among different conditions. Therapeutic approaches range from conservative treatments with clinical observation and antibiotic therapy to urgent surgical interventions, such as appendectomy and cholecystectomy. Laparoscopy stands out as a promising approach, offering advantages in terms of recovery and post-operative morbidity. However, the impact of the COVID-19 pandemic has brought additional challenges to the diagnosis and treatment of acute abdomen, with delays and difficulties in accessing healthcare. This review underscores the importance of a multidisciplinary approach and constant updates among healthcare professionals in addressing acute abdomen, aiming for accurate diagnoses and appropriate therapeutic interventions to improve clinical outcomes and reduce morbidity and mortality associated with this complex clinical condition.

关键词： Component Formatting Style Styling Insert

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Effect of Variety and Plant Spacing on Growth and Yield of Groundnuts (Arachis hypogaea L.)

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Agricultural Sciences 2024年第1期15卷 54-70页

作者： Abukari Iddrisu Eric Adjei Samuel Kwesi Asomaning Kwadwo Gyasi santo Adu Poku Isaac Alexander Danson-Anokye Cocoa Health and Extension division Huni Valley Ghana Department of Agriculture Berekum East Municipal Assembly Berekum Ghana Department of Horticulture and Crop Production School of Agriculture and Technology University of Energy and Natural Resources Sunyani Ghana Glenn High School Winston Salem USA

A field experiment was carried out to determine the effect of variety and plant spacing on yield and growth of groundnuts. The field experiment was laid in a 3 × 3 factorial experiment in a Randomized Complete Block Design (RCBD) with three (3) replications. The factor A included three (3) groundnut varieties (Nkatie Sari, Sum Nutt 22 and Yenyawoso) and Factor B was the three (3) spacing of 30 cm × 15 cm, 30 cm × 30 cm and 30 cm × 40 cm. All recommended agronomic practices were followed. Data was collected from eight (8) tagged plants. Growth data were recorded on plant height, number of branches, number of leaves, and the number of flowers while yield data were collected on the number of flowers, number of pods per plant, 100 seeds weight and the pod yield (kg/ha). The plant spacing significantly influenced (P < 0.05) the growth and yield parameters. Groundnut grown at a spacing of 30 cm × 15 cm produced the maximum plant height, whereas the maximum number of leaves, number of branches and number of flowers were produced from 30 cm × 40 cm. Yenyawoso variety with a wider plant spacing performed better vegetatively among all the varieties. The Yenyawoso variety produced the highest number of pods, 100 seeds weight and pod yield as compared to the other varieties. Also, Yenyawoso at 30 cm × 40 cm spacing and Nkatie Sari at 30 cm × 15 cm spacing produced the maximum pod yield.

关键词： Groundnut Variety Yield Spacing Plant Height

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Sustained neuronal viability by paracrine factors: new opportunities for endothelial progenitor cell secretome

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Neural Regeneration Research 2021年第7期16卷 1429-1430页

作者： Stefano di santo Hans Rudolf Widmer Department of Neurosurgery Neurocenter and Regenerative Neuroscience ClusterUniversity Hospital BernSwitzerland University of BernInselspitalSwitzerland

Despite the big progresses in the field of regenerative medicine, the loss of neurons remains essentially an unresolved *** the different approaches under investigation, there are great expectations on stem and progen... 详细信息

关键词： progenitor strategies. spite

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Paracrine factors for neurodegenerative disorders:special emphasis on Parkinson's disease

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Neural Regeneration Research 2016年第4期11卷 570-571页

作者： Stefano di santo Hans Rudolf Widmer Department of Neurosurgery Neurocenter and Regenerative Neuroscience ClusterUniversity Hospital BernSwitzerland University of Bern

The progressive loss of dopaminergic neurons in the ventral mesencephalon is the main pathological hallmark of Parkinson’s disease（PD）.Drugs currently available only alleviate the principal symptomatic motor-relate... 详细信息

关键词： Paracrine factors for neurodegenerative disorders ECM MSC

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Growth, Development and Yield of Kenaf as Affected by Planting Dates and N Fertilization

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Open Journal of Applied Sciences 2024年第3期14卷 707-720页

作者： Julius Yirzagla Peter Quandahor Iddrisu Yahaya Olivia Aguriboba Akanbelum Listowell Aditwin Akologo John Bokaligidi Lambon Abdul-Wahab M. Imoro Kwadwo Gyasi santo CSIR-SARI Nyankpala Ghana St Vincent College of Education Yendi Ghana Gbewaah College of Education Pusiga-Bawku Ghana CSIR-Head Office Accra Ghana C.K. Tedam University of Technology and Applied Sciences Navrongo Ghana University of Energy and Natural Resources Sunyani Ghana

Kenaf (Hibiscus cannabinus L) consists of various beneficial components like stalks, seeds, leaves, fibers, oils, proteins, allelopathic chemicals, and fiber strands, among other things. Despite the numerous uses of the crop, there is little or no information on optimum agronomic practices such as planting date and N fertilization of the crop in the Upper East Region (UER) of Ghana where the crop is widely cultivated by smallholder farmers. Field experiments were therefore carried out in 2020 and repeated during the 2021 cropping season in the study area. The objective of the study was to determine appropriate planting date and N fertilization for increased kenaf productivity. In each year, the treatments consisted of 3 × 5 factorial combinations of three planting dates (1st July, 7th July and 14th July) and five levels of N (0, 20, 40, 60 and 80 kg/ha) replicated three times. The design of the experiment was a split-plot with the N fertilizer as the main plot and the planting date assigned to sub plot. The results showed that, planting kenaf in early (1st) July or N fertilization at the rate of 60 kg/ha increased plant density, stem height, stem diameter, dry bast and core yields in both cropping seasons.

关键词： Growth Fibres Bast Yield Core Yield

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Nd: Yag laser iridotomy in Shaffer-Etienne grade 1 and 2: angle widening in our case studies

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International Journal of Ophthalmology(English edition) 2015年第4期8卷 709-713页

作者： Sandra Cinzia Carlesimo Luigi di santo Pietro Bruni Aloisa Librando Antonietta Pompea Falace Andrea Barbato Department of Sense Organs Sapienza University of Rome Freelance Scientific Designer

·AIM: To obtain widening of a potentially occludable angle, in according to Kanski’s indications, through preventive Nd:Yag laser iridotomy. The observational study was performed by using gonioscopy for the selection and follow-up of 1165 treated eyes and exploiting Shaffer-Etienne gonioscopic classification as a quality/quantity test of the angle recession.·METHODS: Between September 2000 and July 2012,586 patients were selected at the Outpatients’ Ophthalmological Clinic of the Policlinico Umberto I of Rome in order to undergo Nd: Yag laser iridotomy. A Goldmann type contact lens, Q-switched mode, 2-3defocus, and 7-9 m J intensity with 2-3 impulse discharges were used for surgery.·RESULTS: From as early as the first week, a whole360° angle widening were evident in the patients, thus showing the success of Nd:Yag laser iridotomy in solving relative pupil block. The angle remained narrow by 270° in 14 eyes only, despite repetitions of further treatment with laser iridotomy in a different part of the iris, twice in 10 eyes and three times in 4 eyes.·CONCLUSION: Nd:Yag laser iridotomy revealed itself as being a safe and effective treatment in widening those critical Shaffer-Etienne grade 1 and 2 potentially occludable angles.

关键词： glaucoma gonioscopy intraocular pressure iridotomy narrow angle Nd:Yag laser

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Impact of chitosan-based nanocarriers on cytoskeleton dynamics:Current status and challenges

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BIOCELL 2022年第4期46卷 885-891页

作者： M.CAROLINA di santo AGUSTINA ALAIMO ANA PAULA DOMÍNGUEZ RUBIO OSCAR E.PÉREZ Departamento de Química Biológica Facultad de Ciencias Exactas y NaturalesUniversidad de Buenos AiresBuenos AiresArgentina Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales Consejo Nacional de Investigaciones Científicas y Técnicas(IQUIBICENCONICET)Buenos AiresArgentina

Chitosan-based nanocarriers(CS-NCs)show a promising role in improving drugs and bioactive compounds delivery for ***,the effects exerted by CS-NCs at the cellular level,including their recognition and uptake,have not been fully investigated *** factors,including size,shape,concentration,and surface chemistry of CS-NCs,play an important role in determining the types of intracellular signals *** mechanism of uptake and the involvement of the cytoskeleton during the CS-NCs endocytosis variates among the different cell types as well as further effects observed inside *** the present work,we discuss the effects induced by CS-NCs per se on the cytoskeleton,a key component in cell architecture and *** focus of this report is made on tumoral and normal biological models in which CS-NCs could differentially affect the cell *** recent years reports regarding the impact of CS-NCs on cytoskeleton dynamics and the current techniques for its evaluation are summarized and *** mechanisms underlying cytoskeletal impact after cell exposure to CS-NCs is critical for the design of safest value-added formulations in the biomedical ***,this revision points out some interesting aspects of cytoskeletal changes and cell death encompassing anti-tumoral effects.

关键词： Cytoskeletal dynamics Cellular uptake Endocytosis Nanocarriers Chitosan Bioactive compounds

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