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Demystifying polyphosphate-accumulating organisms relevant to wastewater treatment: A review of their phylogeny, metabolism, and detection

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Environmental Science and Ecotechnology 2024年第5期21卷 1-16页

作者： Lucia Ruiz-Haddad Muhammad Ali mario pronk Mark C.Mvan Loosdrecht Pascal E.Saikaly Environmental Science and Engineering Program Biological and Environmental Science and Engineering(BESE)DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal23955-6900Saudi Arabia Water Desalination and Reuse Center Biological and Environmental Science and Engineering(BESE)DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal23955-6900Saudi Arabia Department of Civil Structural&Environmental EngineeringTrinity College DublinThe University of DublinDublin2Ireland Department of Biotechnology Delft University of TechnologyDelft2629 HZthe Netherlands

Currently,the most cost-effective and efficient method for phosphorus(P)removal from wastewater is enhanced biological P removal(EPBR)via polyphosphate-accumulating organisms(PAOs).This study integrates a literature review with genomic analysis to uncover the phylogenetic and metabolic diversity of the relevant PAOs for wastewater *** findings highlight significant differences in the metabolic capabilities of PAOs relevant to wastewater ***,Candidatus Dechloromonas and Candidatus Accumulibacter can synthesize polyhydroxyalkanoates,possess specific enzymes for ATP production from polyphosphate,and have electrochemical transporters for acetate and *** contrast,Tetrasphaera,Candidatus Phosphoribacter,Knoellia,and Phycicoccus possess PolyP-glucokinase and electrochemical transporters for sugars/amino ***,this review explores various detection methods for polyphosphate and PAOs in activated sludge wastewater treatment ***,FISH-Raman spectroscopy emerges as one of the most advanced detection ***,this review provides critical insights into PAO research,underscoring the need for enhanced strategies in biological phosphorus removal.

关键词： Polyphosphate-accumulating organisms(PAOs) Enhanced biological phosphorus removal (EBPR)Tetrasphaera Ca.accumulibacter Ca.phosphoribacter Knoellia Phycicoccus

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Eight of ten patients return to daily activities, work, and sports after total knee arthroplasty

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World Journal of Orthopedics 2024年第7期15卷 608-617页

作者： Maud Cornelia Wilhelmina Maria Peters Yvette pronk Justus-Martijn Brinkman Department of Research Kliniek ViaSanaMill 5451 AANetherlands Department of Orthopedic Surgery Kliniek ViaSanaMill 5451 AANetherlands

BACKGROUND Besides return to work(RTW)and return to sports(RTS),patients also prefer to return to daily activities(RTA)such as walking,sleeping,grocery shopping,and domestic work following total knee arthroplasty(TKA).However,evidence on the timelines and probability of patients’RTA is *** To assess the percentage of patients able to RTA,RTW,and RTS after TKA,as well as the timeframe and influencing factors of this *** A retrospective cohort study with prospectively collected data was conducted at a medium-sized Dutch orthopedic *** of RTA,RTW,and RTS were performed at 3 mo and/or 6 mo following *** factors en-compassed patient characteristics,surgical characteristics,and preoperative patient-reported *** TKA patients[n=2063;66 years old(interquartile range[IQR]:7 years);47%male;28 kg/m2(IQR:4 kg/m2)]showed RTA ranging from 28%for kneeling to 94%for grocery shopping,with 20 d(IQR:27 d)spent for putting on shoes to 74 d(IQR:57 d)for *** rates varied from 62%for medium-impact work to 87%for low-impact work,taking 33 d(IQR:29 d)to 78 d(IQR:55 d).RTS ranged from 48%for medium-impact sports to 90%for low-impact sports,occurring within 43 d(IQR:24 d)to 90 d(IQR:60 d).One or more of the investigated factors influenced the return to each of the 14 activities examined,with R²values ranging from 0.013 to *** Approximately 80%of patients can RTA,RTW,and RTS within 6 mo after *** is not consistently in-fluenced by predictive *** help set realistic pre-and postoperative expectations.

关键词： Knee Arthroplasty Replacement Return to work Return to daily activities Return to sports

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Garmerwolde污水处理厂提标改造--新增好氧颗粒污泥系统、旁侧流SHARON

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净水技术 2016年第5期35卷 11-16页

作者：陈涛门晓欣李军 m.c.m.van loosdrecht mario pronk 浙江工业大学环境学院浙江杭州310014 LX Environmental L.L.C. RichboroPA18954USA Department of Biotechnology Delft University of TechnologyDelft2601the Netherlands

Garmerwolde污水处理厂原主体工艺采用AB法。为应对不断增加的污水量和更加严格的排放标准,该厂进行了提标改造。2005年主要通过增加旁侧SHARON（2400 kgN/d）以解决污泥消化液处理问题,氨氮去除率95%以上,达到硝化阶段节约能耗25%、反... 详细信息

Garmerwolde污水处理厂原主体工艺采用AB法。为应对不断增加的污水量和更加严格的排放标准,该厂进行了提标改造。2005年主要通过增加旁侧SHARON（2400 kgN/d）以解决污泥消化液处理问题,氨氮去除率95%以上,达到硝化阶段节约能耗25%、反硝化阶段节约外加碳源40%,减少50%的污泥产量。2013年新增独立运行的SBR好氧颗粒污泥系统（Nereda）,增加产能2.86万m3/d,好氧污泥颗粒化后60%颗粒〉1 mm、生物量可稳定达到8 g/L以上、SVI5值稳定在45 mL/g左右,出水TN≤7 mg/L,TP≤1 mg/L,比传统活性污泥系统能耗降低58%-63%、占地减少33%、运行费用节省50%。

关键词：城镇污水处理厂提标改造好氧颗粒污泥 SHARON Nereda

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大跨度冰壳结构设计建造一体化关键技术研究与应用

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建筑结构学报 2020年第S2期41卷 323-329页

作者：武岳刘秀明罗鹏 pronk Arno 哈尔滨工业大学结构工程灾变与控制教育部重点实验室黑龙江哈尔滨150090 哈尔滨工业大学土木工程智能防灾减灾工业和信息化部重点实验室黑龙江哈尔滨150090 哈尔滨工业大学建筑学院黑龙江哈尔滨150090 埃因霍温理工大学建筑与城市规划学院荷兰埃因霍芬5600MB

冰壳结构是一种以冰、雪为主要施工材料建造的空间薄壳建筑,具有材料易获取,造型丰富美观的特点,在冰雪产业和极地开发领域具有较大的应用前景。为促进冰雪建筑结构在我国的推广和创新,提出了大跨度冰壳结构的设计建造一体化技术,主要... 详细信息

冰壳结构是一种以冰、雪为主要施工材料建造的空间薄壳建筑,具有材料易获取,造型丰富美观的特点,在冰雪产业和极地开发领域具有较大的应用前景。为促进冰雪建筑结构在我国的推广和创新,提出了大跨度冰壳结构的设计建造一体化技术,主要从结构热力耦合分析、气膜模板形态控制、喷射施工仿真及结构响应监测等4个方面进行阐述,总结了冰壳结构设计与施工关键技术环节;结合近几年开展的大跨度冰壳结构典型工程案例,介绍了设计施工关键技术在冰壳工程中的应用。相关研究成果可拓宽冰雪建筑的建造规模与结构造型,实现大跨度冰壳结构科学施工与安全评估,也可为制定冰壳结构设计建造标准提供理论与实践依据。

关键词：冰壳结构设计理论施工技术一体化工程实践

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Calcineurin Inhibitors in the Treatment of Adult Autoimmune Hepatitis:A Systematic Review

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Journal of Clinical and Translational Hepatology 2022年第6期10卷 1155-1166页

作者： Martine AMC Baven-pronk Joffre M.Hew,Jr Maaike Biewenga Maarten E.Tushuizen Aad P.van den Berg Gerd Bouma Johannes T.Brouwer Bart van Hoek 无 Department of Gastroenterology and Hepatology Groene Hart HospitalGoudaNetherlands Department of Gastroenterolo-gy and Hepatology Leiden University Medical CenterLeidenNetherlands Department of Gastroenterology and Hepatology University Medical Center GroningenGroningenNetherlands Department of Gastroenterology and Hepatology Amsterdam University Medical Center Location VUAmsterdamNetherlands Reinier de Graaf Medical Center Delft DelftNetherlands Dutch Autoimmune Hepatitis Study Group

Background and Aims:A considerable number of au-toimmune hepatitis(AIH)patients completely or partially fail on first-line *** studies on the use of calcineurin inhibitors(CNIs)in the treatment of AIH have been published without focusing on *** aim was to assess the efficacy of CNIs in the treatment of adult AIH patients,specifically focusing on indication:first-line intolerant and with first-line insufficient response(failure to achieve or maintain remission),and with second versus third-line ***:A literature search included studies on the use of CNIs in adult *** with past or present use of CNIs from the Dutch AIH group cohort were *** primary endpoint was biochemical remission while using *** endpoints were biochemical response,treatment failure,and adverse ***:Twenty studies from the literature and nine Dutch patients were included describing the use of cyclosporine in 59 and tacrolimus in 219 adult AIH *** CNI remission rate was 53%in patients with insufficient response to first-line treatment and 67%in patients intolerant to first-line *** were used as second-line treatment in 73%with a remission rate of 52%and as third-line treatment in 22%with a remission rate of 26%.Cyclosporine was discontin-ued in 13%and tacrolimus in 11%of patients because of adverse ***:CNIs as rescue treatment in adult AIH patients are reasonably effective and safe both with insufficient response or intolerance to previous *** studies are needed.

关键词： Autoimmune hepatitis Cyclosporine Tacrolimus Calcineurin inhibi-tor

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数码相机用户伴侣第一版

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丛书名：万水数字影像技术系列

1998年

作者： (美)塞耶(Sawyer B.) 普朗克(pronk R.)

来源：畅想之星图书光盘版（南... 评论

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沉积物和悬浮颗粒物在岩溶水系统污染物衰减与运移中的作用(英文)

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中国岩溶 2009年第2期28卷 113-121页

作者： Nico Goldscheider Michiel pronk Jakob Zopfi Centre of Hydrogeology University of Neuchatel 2009 Neuchatel Switzerland Institute of Geology and Palaeontology University of Lausanne 1015 Lausanne Switzerland

本文讨论了沉积物和悬浮颗粒物/胶体在岩溶水系统污染物衰减与运移中的作用,介绍了关于瑞士某岩溶水系统内颗粒物与微生物污染间关系的试验结果。该试验场包括一个接纳农田排水的落水洞及与其相连的两个泉,其中一个泉是供水水源地。利... 详细信息

本文讨论了沉积物和悬浮颗粒物/胶体在岩溶水系统污染物衰减与运移中的作用,介绍了关于瑞士某岩溶水系统内颗粒物与微生物污染间关系的试验结果。该试验场包括一个接纳农田排水的落水洞及与其相连的两个泉,其中一个泉是供水水源地。利用便携式粒子计实时监测泉水中颗粒分布的变化情况,同时对浊度、总有机碳和其它参数进行连续监测;并对水中E型大肠菌群进行了分析。在暴雨过后,观测到了浊度的两种不同表现:在泉排泄量增加时,浊度最初表现为脉状水动力条件下岩溶系统内沉积物的二次运移;几天后观测到的浊度则表明水已从落水洞到了泉口,常常具有高的总有机碳、硝酸盐及E型大肠菌群。颗粒分布分析结果差异更大:早期的浊度是不同粒径颗粒物的混合,而后期的浊度更多的是由较细颗粒构成,因为大颗粒物已沉积在落水洞到泉口之间的岩溶系统内。E型大肠菌群与0.9～1.5μm颗粒物之间具有很好的相关性。因而较细颗粒的相对增加可应用于微生物污染"早期预报系统"。除了水污染,颗粒分布还可以帮助我们研究岩溶环境的其它问题,如土壤侵蚀。

关键词：岩溶水系统浊度颗粒分布沉积物运移地下水污染粪便细菌微生物病原体

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Cost-effectiveness in Clostridium difficile treatment decision-making

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World Journal of Clinical Cases 2015年第11期3卷 935-941页

作者： Mark JC Nuijten Josbert J Keller Caroline E Visser Ken Redekop Eric Claassen Peter Speelman Marja H pronk Ars Accessus Medica HAGA Teaching Hospital Clinical Microbiologist AMC iMTA and BMG EUR EUR AMC Europe-ExPro

AIM: To develop a framework for the clinical and health economic assessment for management of Clostridium difficile infection(CDI).METHODS: CDI has vast economic consequences emphasizing the need for innovative and cost effective solutions, which were aim of this study. A guidance model was developed for coverage decisions and guideline development in CDI. The model included pharmacotherapy with oral metronidazole or oral vancomycin, which is the mainstay for pharmacological treatment of CDI and is recommended by most treatment ***: A design for a patient-based cost-effectiveness model was developed, which can be used to estimate the cost-effectiveness of current and future treatment strategies in CDI. Patient-based outcomes were extrapolated to the population by including factors like, e.g., person-to-person transmission, isolation precautions and closing and cleaning wards of hospitals. CONCLUSION: The proposed framework for a population-based CDI model may be used for clinical and health economic assessments of CDI guidelines and coverage decisions for emerging treatments for CDI.

关键词： Clostridium difficile infection Guidance Cost-effectiveness Model Standardisation Decision making

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Buoycrete and Membrane Molding

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Journal of Civil Engineering and Architecture 2022年第7期16卷 362-373页

作者： Arno pronk and Guido Visch Department Built Environment Unit Structural DesignEindhoven University of TechnologyThe Netherlands Baggermaatschappij Boskalis B.V. The Netherlands

In this study,the authors present Buoycrete,a new material and work method invented by the company *** is a light-weight concrete that is able to float and does not dissolve in *** is based on a unique combination of different *** paper will start with an overview of concrete structures in combination with fabrics and will present the structural behavior,construction methods and applications of *** demonstrates that Buoycrete combined with fabric formwork creates new possibilities for a broad kind of applications,for instance,the realization of façade elements,shell structures and civil engineering.

关键词： Buoycrete floating concrete neutrally buoyant concrete light weight concrete ductility membrane moulding freeform design extrusion

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Intestinal perforation as an early complication in Wegener's granulomatosis

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World Journal of Gastrointestinal Surgery 2010年第5期2卷 169-171页

作者： Morsal Samim Apollo pronk Paulus Menno Verheijen Department of Surgery Diakonessenhuis Bosboomstraat 1 3582 KE Utrecht The Netherlands

We present the case of a young man with involvement of the gastrointestinal tract in the early phase of Wegener's granulomatosis. The patient presented at the emergency department with sudden onset of abdominal pain, nausea and vomiting. Radiography work up was negative for free air although ultrasound examination showed extraluminal intra-abdominal fluid. Exploratory laparotomy showed perforation of the jejunum. The bowel was vital except for this small segment of jejunum. A 5-cm long segment of jejunum was resected which revealed ulcerative inflammation accompanied by occluded arteries of the small intestine. Although intestinal perforation in Wegener's granulomatosis is uncommon, several cases have been previously reported. Intestinal involvement in the early phase of the disease is even more uncommon. This case combined with prev iously reported cases emphasizes the possibility of gastrointestinal manifestation early in Wegener's disease.

关键词： Wegener’s granulomatosis Intestinal tract Perforation

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