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Somatotype Components, Aerobic Fitness and Grip Strength in Kuwaiti Males and Females

Health 2016年第13期8卷 1349-1355页

作者： Jasem Ramadan Alkandari mario barac nieto Department of Physiology Faculty of Medicine Kuwait University Kuwait City Kuwait

Introduction and Objective: We investigated the association of endo-, meso- and ecto-morphic components of somatotype with aerobic power, mid-trunk flexibility and grip strength. Methods: Healthy male (n = 226) and female (n = 86) subjects, aged 9 - 55 years, sedentary (n = 154) or participating in sports (n = 158) were studied. Anthro-pometrics (height, weight, 8 skin folds, arm and calf circumferences, elbow and knee diameters), maximal exercise O2 uptake, mid trunk flexibility, right and left grip strength were measured. Results: Sedentary adult females were endomorphic with mesomorph tendency, and had low aerobic power (27.8 ± 0.6 ml/Kg·min) and low (48.7 ± 1 Kg) grip strength. Sedentary males (young and adults) and Sports adult males were mesomorph with endomorphic tendency. Sports junior males were balanced mesomorph. Aerobic power was 54.1 ± 0.9 ml/Kg·min in sports young males, 53.8 ± 0.9 ml/Kg·min in sports adult males, 41.2 ± 4.3 ml/Kg·min in sedentary young males, and 39.5 ± 1 ml/Kg·min in sedentary adult males. Grip strength was 89.9 ± 1.7 Kg in sports adult males, 86.7 ± 2 Kg in sedentary adult males, 75.6 ± 2.2 Kg in sports junior males and 52 ± 9.1 Kg in young sedentary males. Step-wise multiple regression analysis of somatotype components on aerobic power revealed dominant negative contribution (P 2 = 0.57, 57%), and small but significant positive contributions of mesomorphy (0.6%) and ectomorphy (0.6%): Aerobic power = [56.1 - 4.3 (endomorphy) + (mesomorphy) + 1.4 (ectomorphy)] ± 9.1 SEE. Height and somatotype components accounted for 69% of the variance (R2) in grip strength;height had greatest contribution (60%): Grip Strength = [1.7 (Height) - 6.5 (ectomorphy) - 3.4 (endomorphy) - 2 (mesomorphy) - 200] ± 12.9 SEE. Measured variables accounted for <2% of flexibility variance. Conclusion: Endomorphy contributes greatly and negatively to variance in aerobic power. Body height was the anthropometric variable with th

关键词： Maximal Oxygen Uptake Endomorphy Mesomorphy Ectomorphy Grip Strength

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Peak O<sub>2</sub>Uptake Correlates with Fat Free Mass in Athletes but Not in Sedentary Subjects

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Health 2019年第1期11卷 40-49页

作者： Jasem Ramadan AlKandari mario barac nieto Department of Physiology Faculty of Medicine Kuwait University Kuwait City Kuwait

Objective: To characterize relationships between peak O2 uptake (VO2max) and fat free mass (FFM) in adult sedentary and in young and adult athletes. Methods: Healthy adult male sedentary workers or students reporting no regular physical activity in the last six months (n = 61, 31.0 ± 0.95 years) and young (n = 63, 15.8 ± 0.16 years) or adult (n = 85, 25.9 ± 0.48 years) males athletes were studied. Sports were classified according to their MET intensity. Bruce’s treadmill protocol served to measure VO2max. Weight and seven skin-fold thicknesses were used to estimate body density and FFM. Subjects signed informed-consent forms before the tests. Results: The significant correlations (R2 = 0.48, p 2max or of log FFM with log VO2max (R2 = 0.53, p 2 = 0.34 & 0.30), and not significant (R2 = 0.19 & 0.17, p > 0.05) in sedentary subjects. Stepwise multiple regression analysis (R2 = 0.65) indicated that VO2max depended on FFM, heart rates and MET intensity of practiced sport in athletes. In sedentary subjects VO2max was insignificantly (R2 = 0.18) related to flexibility. Discussion: Skin-fold based FFM reliably reflects maximally active muscle mass in young athletes, to a lesser extent in adult athletes but not in adult sedentary subjects. In sedentary, VO2max is often limited by local pain and fatigue and does not reflect the capacity of the oxygen extraction system. In sedentary, varying proportions of surface fat, muscle and bone increase variability in the relationship between skinfolds and FFM.

关键词： VO2max Lean Body Mass Physical Activity Age Regression Analysis

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Health 2021年第5期13卷 505-525页

作者： Nadia Garashi Jasem Ramadan Al-Kandari mario barac nieto Department of Physiology Health Sciences Center Kuwait University Jabriya Kuwait

The incidence of major chronic Non Communicable Diseases (NCD) medically diagnosed or treated, was studies in a cross section of Kuwait adult population as well as their daily levels of physical activity (PA) as recalled by the International Physical Activity Questionnaire, IPAQ. A group of 1957 subjects 17 - 65 years of age, representative of the Kuwait population was selected using last year high school students and their relatives as well as government workers in each Kuwait governorate. Descriptive statistics, frequency tables, chi square and Fisher tests were used. ANOVA or Mann Whitney and Kruskal-Wallis tests were used for comparisons. The percentage of subjects in the low categorical PA level (from IPAQ) is high (29.4%) even at a young age (17 - 24), similar in prevalence to overweight/obesity (30%). At age 45, obesity increases to 40% with little change in % subjects of low PA. Weighted average categorical PA was 1280 ***/week reflecting that the majority (40%) of subjects belonged to the moderate PA category. A high proportion (38%) of subjects in the 17 - 24 age category contributed to the observed level of PA activity. Incidence of overweight and obesity increased from 30 to more than 55% from the second to the sixth decade of life. Hyperlipidemias increased in incidence from 8% to 45% of the sample from the third to the sixth decades of age. Hypertension and diabetes increased from the 4th to the 6th decades of life to affect from 14% to 40% and from 10% to 36% of the studied population, respectively. Incidence of Heart Disease increased from 9% to 15% of the sample population, between the 5th and 6th decades of life. The data indicate a sequence of events, initiated by overweight and obesity as early as in the 2d decade of life, followed by hyperlipidemia in the 3d decade, diabetes and hypertension in the 4th, and heart disease in the 5th decade of life. Changes

关键词： Daily Physical Activity IPAQ Recall Survey Kuwait Cardiovascular Diabetes Hypertension Overweight Obesity Hyperlipidemia Age Adults

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Immune Reactive Ezrin Surface Area Increases in Glomerular Podocytes of STZ Diabetic Rats Precede Their Detachment, Is Prevented by Phlorizin But Not by Insulin

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Journal of Diabetes Mellitus 2020年第2期10卷 27-40页

作者： Slava Malatiali Issam Francis Musleeha Chesor Gavin Welsh Moin Saleem mario barac-nieto Departments of Physiology Faculty of Medicine Kuwait University Safat Kuwait Pathology Faculty of Medicine Kuwait University Safat Kuwait University of Bristol Pediatric Nephrology Bristol UK Retired 9443 Hickory Limb Colusmbia MD USA

Glomerular tuft immune reactive Ezrin surface area (EzA) and fraction of EzA to total glomerular tuft area significantly increased, indicating podocyte growth, rounding and altered cytoskeletal interactions at 1 week of STZ diabetes. Podocyte number per glomerulus (WT1+ nuclei) did not change indicating no detachment, but density decreased due to tuft hypertrophy. Treatment with PLZ or Insulin for one week, prevented increase in proteinuria and hyperglycemia but not the decrease in podocyte density. PLZ but not Insulin prevented increase in ezrin positive area in glomeruli and per podocyte. In podocytes in culture neither 25 mM glucose with or without PLZ (2.5 or 25 uM) altered Ezrin expression measured in western blots. In summary, the Ezrin positive glomerular surface area increase seen after 1 week of STZ diabetes, reflects altered podocyte morphology and cytoskeletal interactions, prevented by PLZ but not by insulin. Ezrin area increase preceded podocyte detachment and in podocytes in culture is not associated with increases in podocyte Ezrin protein expression. It is a likely precursor of shape changes in podocytes and of alterd interactions with basement membrane that contribute to detachment and thickening. Glomerular capillary tuft hypertrophy and reduced podocyte density persisted despite PLZ or insulin treatments, independently of levels of glycemia and of proteinuria.

关键词： Diabetes. Hyperglycemia Glomerular Hypertrophy Phlorizin Podocyte Density Ezrin

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Practical Use of Stairs to Assess Fitness, Prescribe and Perform Physical Activity Training

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Health 2016年第13期8卷 1402-1410页

作者： Jasem Ramadan Al Kandari Salman Mohammad Ruqayyah Al-Hashem Girma Telahoun mario barac-nieto Department of Physiology Faculty of Medicine Kuwait University Al-Khaldiya Kuwait Department of Physical Education College of Basic Education The Public Authority of Applied Education and Training Adailiyah Kuwait

Aim: Evaluating climbing stairs for prescription and implementation of physical activity regimes. Methods: Healthy females (F, n = 14), and males (M, n = 15) participated. By climbing 100 steps of stairs with 0.173 m height, Heart rate (HR) and oxygen uptake were measured throughout the floors;Blood pressure (BP) was measured at ground and the 5th floors only. Results: Energy increased from 2 to 7.6 was metabolic equivalents (METs = 3.5 ml O2/***) at 17.3 m elevation in 2 min. at the 5th floor, and percent Heart Rate Reserve (%HRR) was 66.17% in F and 48.7% in M, proportional to their aerobic efforts. Average climbing efficiency was 15.8 ± 2.3% (n = 29). Aerobic capacity estimated dividing the highest work rate (17.3 Kg.m/*** × 0.00239 = 0.0207 Kcal/***), by fractional effort (F = 0.6617, M = 0.487) and fractional efficiency (0.158), at 5 Kcal/L O2 was 0.040 in F and 0.054 L O2/*** in M. Minimum training intensity reached at the 3rd floor by F. In M the highest %HRR reached was 48.7% at the 5th floor, insufficient for training. Conclusions: Stairs used for submaximal evaluation of aerobic capacity and for target intensity prescription. Training, levels climbed, repetitions per day (if 5, 100 Kcal per day, ascending) and number of days/week are adjusted. Full regime requires up to 7.6 METs, a total of 532 and 140 ***/week ascending and descending, respectively. Intensities >7.6 MET, climbing rate should be >8.65 m/min. Limiting ascent to 1 (3.5 METs) or 2 (5.5 METs) floors or only descents (2 - 3 METs) may be used for unfit subjects. This method is useful for those with no access to sophisticated facilities.

关键词： Stair Climbing Descent Heart Rate Reserve Aerobic Effort Oxygen Cost Work Output Efficiency Aerobic Capacity Exercise Prescription Training

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Reassessing the AMPK-MTORC1 balance in autophagy in the central nervous system

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Neural Regeneration Research 2025年第11期20卷 3209-3210页

作者： Marta García-Juan mario Villa Irene Benito-Cuesta Lara Ordónez-Gutiérrez Francisco Wandosell Centro de Biología Molecular“Severo Ochoa”(CSIC-UAM) Nicolas Cabrera 1Universidad Autónoma de MadridMadridSpain Fisiología Animal Departamento de BiologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain Department of Clinical Neuroscience CMM Karolinska Universitetssjukhuset SolnaStockholmSweden Departamento de Bioquímica y Biología Molecular Universidad Complutense de MadridMadridSpain Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas(CIBERNED) MadridSpain

Autophagy is a cellular degradation and recycling system,indispensable for cellular and organ development,homeostasis,and *** cellular process is evolutionarily highly conserved to quality control of many proteins and dysfunctional organelles,which finally recycle components as amino *** process is effective during normal physiology as part of anabolism and plays an additional important role during starvation(Dikic and Elazar,2018).Different types of autophagy have been chara cterized based on their dynamic,mechanism of action,target substrates,and protein *** of them are macroautophagy(hereafter called"autophagy"),microa utophagy,and chape rone-media ted autophagy(Fleming et al.,2022).

关键词： homeostasis system hereafter

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The complex Maxwell stress tensor theorem:The imaginary stress tensor and the reactive strength of orbital momentum.A novel scenery underlying electromagnetic optical forces

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Light(Science & Applications) 2022年第11期11卷 2655-2675页

作者： Manuel nieto-Vesperinas Xiaohao Xu Instituto de Ciencia de Materiales de Madrid Consejo Superior de Investigaciones Cintificas.Campus de CantoblancoMadrid 28049Spain State Key Laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision MechanicsChinese Academy of SciencesXi'an 710119China Institute of Nanophotonics Jinan UniversityGuangzhou 511443China

We uncover the existence of a universal phenomenon concerning the electromagnetic optical force exerted by light or other electromagnetic waves on a distribution of charges and currents in general,and of particles in *** conveys the appearence of underlying reactive quantities that hinder radiation pressure and currently observed timeaveraged *** constitutes a novel paradigm of the mechanical effciency of light on matter,and completes the landscape of the optical,and generally electromagnetic,force in photonics and classical electrodynamics;widening our understanding in the design of both llumination and particles in optical manipulation without the need of increasing the illuminating power,and thus lowering dissipation and *** show that this may be accomplished through the minimization of what we establish as the reactive strength of orbital(or canonical)momentum,which plays against the optical force a role analogous to that of the reactive power versus the radiation effciency of an *** long time overlooked quantity,important for current progress of optical manipulation,and that stems from the complex Maxwell theorem of conservation of complex momentum that we put forward,as well as its alternating flow associated to the imaginary part of the complex Maxwell stress tensor,conform the imaginary Lorentz force that we introduce in this work,and that like the reactive strength of orbital momentum,is antagonistic to the well-known time-averaged force;thus making this reactive Lorentz force indirectly observable near wavelengths at which the time-averaged force is *** Minkowski and Abraham momenta are also addressed.

关键词： imaginary tensor orbital

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Application of nanotechnology to dentistry:Impact of graphene nanocomposites on clinical air quality

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World Journal of Clinical Cases 2025年第8期13卷 1-7页

作者： Ruth Rodríguez Montaño mario A Alarcón-Sánchez Melissa Martínez nieto Juan J Varela Hernández Sarah M LomelíMartínez Department of Health and Illness as an Individual and Collective Process University Center of TlajomulcoUniversity of GuadalajaraTlajomulco de Zuñiga 45641JaliscoMexico Institute of Research in Dentistry Department of Integral Dental ClinicsUniversity Center of Health SciencesUniversity of GuadalajaraGuadalajara 44340JaliscoMexico Department of Biomedical Science Faculty of Chemical-Biological SciencesAutonomous University of GuerreroGuerrero 39090Mexico Instituto Odontológico del Pacífico Sur Chilpancingo de los Bravo 39022Mexico Independent Researcher Tijuana 22116Baja CaliforniaMexico Department of Medical and Life Sciences Centro Universitario de la CiénegaUniversidad de GuadalajaraOcotlan 47810JaliscoMexico Master of Public Health Department of Well-being and Sustainable DevelopmentCentro Universitario del NorteUniversidad de GuadalajaraOcotlan 46200JaliscoMexico

Concerns about air quality in dental clinics where aerosol generation during procedures poses significant health risks,have prompted investigations on advanced disinfection *** editorial describes the strengths and limitations of ventilation and aerosol control measures in dental offices,especially with respect to the use of graphene *** potential of graphene nanocomposites as an innovative solution to aerosol-associated health risks is examined in this review due to the unique properties of graphene(e.g.,high con-ductivity,mechanical strength,and antimicrobial activity).These properties have produced promising results in various fields,but the application of graphene in dentistry remains *** recent study by Ju et al which was published in World Journal of Clinical Cases evaluated the effectiveness of graphene-based air disinfection systems in dental *** study demonstrated that graphene-based disinfection techniques produced significant reductions in suspended particulate matter and bacterial colony counts,when co-mpared with traditional *** these positive results,challenges such as material saturation,frequency of filter replacement,and associated costs must be addressed before widespread adoption of graphene-based disinfection techniques in clinical ***,there is need for further research on material structure optimization,long-term safety evaluations,and broader clinical applications,in order to maximize their positive impact on public health.

关键词： Graphene Nanocomposites Antibacterial activity Biomedical applications Air disinfection

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CONTROLLABILITY AND OPTIMALITY OF LINEAR TIME-INVARIANT NEUTRAL CONTROL SYSTEMS WITH DIFFERENT FRACTIONAL ORDERS

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Acta Mathematica Scientia 2015年第5期35卷 1003-1013页

作者：丁小丽 Juan J.nieto Department of Mathematics Xi’an Polytechnic University Departamento de Análisis Matemático Facultad de MatemáticasUniversidad de Santiago de Compostela Department of Mathematics Faculty of Science King Abdulaziz University

Control systems governed by linear time-invariant neutral equations with different fractional orders are considered. Sufficient and necessary conditions for the controllability of those systems are established. The existence of optimal controls for the systems is given. Finally, two examples are provided to show the application of our results.

关键词： controllability optimality neutral equations different fractional orders

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Non-albicans candidemia in cancer patients as an increasing health problem:A comprehensive review and meta-analysis

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Asian Pacific Journal of Tropical Medicine 2022年第9期15卷 387-399页

作者： Aynaz Ghojoghi Maryam Erfaninejad Ehsan Ahmadpour Eisa Nazar Aleksandra barac Mahnaz Fatahinia Department of Medical Mycology School of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Infectious and Tropical Diseases Research Center Tabriz University of Medical SciencesTabrizIran Department of Biostatistics School of HealthMashhad University of Medical SciencesMashhadIran Clinic for Infectious and Tropical Diseases Clinical Centre of SerbiaBelgradeSerbia

Objective:To evaluate the prevalence of Candida species in cancer patients with candidemia around the world,and to identify related risk factors and their antifungal resistance,with an emphasis on non-albicans Candida species(NACs).Methods:The published papers related to the subject were systematically searched in databases of MEDLINE(including PubMed),Web of Science,Scopus,Science Direct,and Google Scholar between the 1st January 2000 and 21st April ***:Among the 4546 records,69 studies met the inclusion *** pooled prevalence of NACs in cancer patients with candidemia was 62%(95%CI 58%-67%;I2=94.85%,P=0.00).Based on type of cancer,the pooled prevalence of NACs in hematologic and solid cancer patients were 68%(95%CI 65%-70%)and 52%(95%CI 49%-54%),*** NACs,Candida(C.)parapsilosis was the most frequently isolated organism followed by *** and *** addition,the therapeutic usage of antibiotics was found as the most common risk factor,accounting for 85%(95%CI 81%-89%)and central venous catheter accounting for 69%(95%CI 62%-77%).Conclusions:The incidence of Candida bloodstream infections among cancer patients is a growing concern,especially when the etiologic agents of candidemia tend to shift towards NACs.

关键词： Candidemia Non-albicans Candida Cancer Epidemiology Systematic review Meta-analysis

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