检索结果-南通市图书馆

Unsteady Inflow Effects on the Wake Shed from a High-Lift LPT Blade Subjected to Boundary Layer Laminar Separation

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2012年第2期21卷 97-108页

作者： Francesca Satta marina Ubaldi Pietro Zunino Università degli Studi di Genova

An experimental investigation on the near and far wake of a cascade of high-lift low-pressure turbine blades subjected to boundary layer separation over the suction side surface has been carried out, under steady and unsteady inflows. Two Reynolds number conditions, representative of take-off/landing and cruise operating conditions of the real engine, have been tested. The effect of upstream wake-boundary layer interaction on the wake shed from the profile has been investigated in a three-blade large-scale linear turbine cascade. The comparison between the wakes shed under steady and unsteady inflows has been performed through the analysis of mean velocity and Reynolds stress components measured at midspan of the central blade by means of a two-component crossed miniature hot-wire probe. The wake development has been analyzed in the region between 2% and 100% of the blade chord from the central blade trailing edge, aligned with the blade exit direction. Wake integral parameters, half-width and maximum velocity defects have been evaluated from the mean velocity distributions to quantify the modifications induced on the vane wake by the upstream wake. Moreover the thicknesses of the two wake shear layers have been considered separately in order to identify the effects of Reynolds number and incoming flow on the wake shape. The self-preserving state of the wake has been looked at, taking into account the different thicknesses of the two shear layers. The evaluation of the power density spectra of the velocity fluctuations allowed the study of the wake unsteady behavior, and the detection of the effects induced by the different operating conditions on the trailing edge vortex shedding.

关键词： Wake-wake unsteady interaction high-lift blade profiles low-pressure turbine blade wake.

Synthesis of biodegradable Mg-Zn alloy by mechanical alloying: Statistical prediction of elastic modulus and mass loss using fractional factorial design

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2018年第4期28卷 687-699页

作者： Emee marina SALLEH Zuhailawati HUSSAIN Sivakumar RAMAKRISHNAN Biomaterials Niche Area School of Materials and Mineral Resources EngineeringEngineering CampusUniversiti Sains Malaysia14300 Nibong TebalPenangMalaysia School of Applied Physics Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 UKM BangiSelangorMalaysia

Biodegradable Mg-Zn alloy was synthesized using mechanical alloying where a statistical model was developed using fractional factorial design to predict elastic modulus and mass loss of the bulk *** effects of mechanical alloying parameters(i.e.,milling time,milling speed,ball-to-powder mass ratio and Zn content)and their interactions were investigated involving 4 numerical factors with 2 replicates,thus 16 runs of two-level fractional factorial *** of analysis of variance(ANOVA),regression analysis and R2 test indicated good accuracy of the *** statistical model determined that the elastic modulus of biodegradable Mg-Zn alloy was between 40.18 and 47.88 GPa,which was improved and resembled that of natural bone(30-57 GPa).Corrosion resistance(mass loss of pure Mg,33.74 mg)was enhanced with addition of 3%-10%Zn(between 9.32 and 15.38 mg).The most significant independent variable was Zn content,and only the interaction of milling time and ball-to-powder mass ratio was significant as P-value was less than ***,mechanical properties(represented by elastic modulus)and corrosion resistance(represented by mass loss)of biodegradable Mg-Zn alloy can be statistically predicted according to the developed models.

关键词： biodegradable Mg-Zn alloy mechanical alloying fractional factorial design elastic modulus mass loss

跨媒介表征:论亚历山大·格林小说中的文学图像

在线全文

学校读者我要写书评

暂无评论

广东开放大学学报 2024年第2期33卷 64-69页

作者：布哈罗娃·玛丽娜天津师范大学天津300382

俄国白银时代重要作家亚历山大·格林在其小说中擅用绘画元素呈现浪漫主义的艺术审美,绘画成为小说文本的媒介呈现。拥有良好艺术功底的格林惯常以绘画作为介质实现小说文本的艺术追求,通过“文学图像”的活现,格林小说中语像和图像“... 详细信息

俄国白银时代重要作家亚历山大·格林在其小说中擅用绘画元素呈现浪漫主义的艺术审美,绘画成为小说文本的媒介呈现。拥有良好艺术功底的格林惯常以绘画作为介质实现小说文本的艺术追求,通过“文学图像”的活现,格林小说中语像和图像“以图言说”“语图互仿”与“语图互文”的动态关系呈现,使得小说人物塑造得更为丰满,推动了小说情节叙事,打通了文本空间与现实空间的桎梏,促使人们通过观赏感受到艺术再现以及艺术与现实之间的融合。亚历山大·格林以绘画植入小说文本,实现了跨媒介、跨文本的融合,从而形成了其创作的独特性。

关键词：亚历山大·格林文学图像绘画框架艺术再现

Autophagy inhibition: a new therapeutic target in spinal muscular atrophy

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2018年第5期13卷 813-814页

作者： Antonio Piras marina Boido Neuroscience Institute Cavalieri Ottolenghi (NICO) Dept. Neuroscience University of Torino

Spinal muscular atrophy（SMA）is a hereditary pediatric motor neuron（MN）disease：survival motor neuron 1（SMN1）gene mutation determines MN degeneration and,consequently,muscle atrophy,breathing and swallowing difficulties,and,in the most severe cases,premature death.A second unaffected gene（SMN2）is present,but it can only produce a limited amount of functional protein,modulating the disease severity and progression.

关键词： Figure SMN a new therapeutic target in spinal muscular atrophy SMA

5-ASA in ulcerative colitis:Improving treatment compliance

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第35期15卷 4353-4355页

作者： Cosimo Prantera marina Rizzi Department of Gastroenterology Azienda Ospedaliera San Camillo-ForlaniniCirconvallazione Gianicolense 8700152 RomeItaly Department of Gastroenterology University Campus Bio Medicovia Alvaro del Portillo 20000128 Rome Italy

5-aminosalicylic acid(5-ASA)compounds are a highly effective treatment for ulcerative colitis(UC).While UC patient compliance in clinical studies is over 90%, only 40%of patients in every day life take their prescribed *** to medication has been emphasized recently by a Cochrane meta-analysis that has suggested that future trials of 5-ASA in UC should look at patient compliance rather than drug efficacy. Better compliance can be obtained by reducing the number of tablets and times of *** that the 5-ASA formulations have different delivery systems that split the active moiety in various regions of the intestine,it is particularly important that an adequate dose of the drug arrives at the inflamed part of the colon.5-ASA Multi matrix(MMx)is a novel,high strength(1.2 g),oral formulation designed for oncedaily *** releases the active moiety throughout the *** studies with this compound have shown that it is as effective as 5-ASA enema in the treatment of mild-to-moderate,left-sided UC,and is comparable to a pH-dependent,delayed release 5-ASA (Asacol ),even if given once ***,the effectiveness in the acute phase of UC has been confirmed also in *** conclusion,at present,5-ASA MMx seems theoretically the best agent for maintaining patient compliance,and consequently,treatment effectiveness.

关键词： 5-aminosalicylic acid Mesalamine Multi matrix Patient compliance Ulcerative colitis

Alien invasive species in Siberia:current status and problem

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Arid Land 2013年第4期5卷 428-433页

作者： marina V OLONOVA YuanMing ZHANG Tomsk State University Lenin ave.36Tomsk 634036Russia Key Laboratory of Biogeography and Bioresource in Arid Land Xinjiang Institute of Ecology and GeographyChinese Academy of Sciences

Although alien and invasive plant species have been researched extensively in the European part of Russia,the situation in Siberia is another ***,alien and invasive species in Siberia have not received much attention because this problem was not especially acute in *** lack of attention on alien and invasive species in Siberia is attributed to three major reasons：1） Low vegetative productivity and sparse human populations in the Siberian territory have limited botanical research interest in the area.2） Severe Siberian climate likely prevents many alien and invasive species from increasing their distribution into Siberia.3） Most Siberian plant communities have not been human-transformed and thus may be resistant to ***,recent increased economic activities have resulted in increasing plant migration to Siberia,and this process should be ***,global environmental changes may also have made Siberia more favorable for more alien and invasive ***,research on alien and invasive species has begun in the Altai-Sayan region（Western Siberia） and the Magadan region （Northeastern Asia）.

关键词： alien invasive plants global climate change economic development Siberia

Measurements of Laminar Burning Velocities of Alternative Fuels:Application in Transport and Aerospace

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2023年第2期32卷 503-512页

作者： RICHTER Sandra BRAUN-UNKHOFF marina NAUMANN Clemens German Aerospace Center(DLR) Institute of Combustion TechnologyDepartment of Chemical Kinetics and AnalyticsStuttgart 70569Germany

The laminar burning velocity belongs to the fundamental combustion properties of fuels being a measure for their heat release,flame length,as well as reactivity and combustion stability,and thus,may impact the design of burners and combustion ***,these experimental data are needed for the validation and optimization within the construction and development of detailed chemical kinetic reaction *** this study,an overview of the different applications of fuel characterization regarding the specific area of interest(road transport,aviation,and aerospace)will be *** on the application,effects of different molecular characteristics on the laminar burning velocity are evaluated:the presence of oxygen atoms and the grade of branching in a specific fuel molecule as well as the difference in the type of a chemical bond,here,single and double *** of alternative fuels being discussed in the present study are:(Ⅰ)oxymethylene ether(OMEn)in the field of road transport;(Ⅱ)a paraffinic Alcohol-to-Jet fuel as sustainable aviation fuel;and(Ⅲ)mixtures of ethane or ethene with nitrous oxide as green propellants for rocket propulsion applications.

关键词： laminar burning velocity alternative sustainable fuels road transport aviation fuels green propellants

Photochemical degradation of nonylphenol in aqueous solution: The impact of pH and hydroxyl radical promoters

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2013年第7期25卷 1326-1330页

作者： Aleksandr Dulov Niina Dulova marina Trapido Department of Chemical Engineering Tallinn University of Technology

The degradation of nonylphenol （NP） in aqueous solution with UV, H202/UV, and Fenton/photo-Fenton processes was studied. The efficacy of direct and hydrogen peroxide photolysis proved to be dependent on the pH value. The addition of H202 to UV treatment improved NP degradation. The application of UV photolysis and the H202/UV system at pH 7 resulted in low pseudo first-order rate constants at 104 sec1 . In the experiments at elevated pH values the pseudo-first order rate constants increased to 103 sec1 . The efficacy of the Fenton process was lower in comparison with UV and hydrogen peroxide photolysis. The addition of UV irradiation to the H202/Fe2＋ system substantially improved NP degradation efficacy. In terms of performance, the photo-Fenton process was similar to the H202/UV process. The most favourable process for complete nonylphenol degradation considering both operational cost and treatment efficacy was H202/UV at pH 11 and 250 μmol/L H202 .

关键词： AOPs endocrine disrupting compound photo-Fenton process photolysis UVC radiation

Role of nuclear receptors in breast cancer stem cells

在线全文

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2016年第3期8卷 62-72页

作者： Alessio Papi marina Orlandi Department of Biological Geological and Environmental Science (BiGea) University of Bologna

The recapitulation of primary tumour heterogenity and the existence of a minor sub-population of cancer cells,capable of initiating tumour growth in xenografts on serial passages, led to the hypothesis that cancer stem cells(CSCs) exist. CSCs are present in many tumours, among which is breast cancer. Breast CSCs(BCSCs) are likely to sustain the growth of the primary tumour mass, as wellas to be responsible for disease relapse and metastatic spreading. Consequently, BCSCs represent the most significant target for new drugs in breast cancer therapy. Both the hypoxic condition in BCSCs biology and proinflammatory cytokine network has gained increasing importance in the recent past. Breast stromal cells are crucial components of the tumours milieu and are a major source of inflammatory mediators. Recently, the antiinflammatory role of some nuclear receptors ligands has emerged in several diseases, including breast cancer. Therefore, the use of nuclear receptors ligands may be a valid strategy to inhibit BCSCs viability and consequently breast cancer growth and disease relapse.

关键词： Cancer stem cells Hypoxia Inflammation Nuclear receptors Retinoids Peroxisome proliferator-activator receptors