检索结果-南通市图书馆

How to properly evaluate cardiac vagal tone in oncology studies:a state-of-the-art review

Journal of the National Cancer Center 2024年第1期4卷 36-46页

作者： Pierrick Martinez marilyne grinand Saïda Cheggour Jérôme Taieb Géraud Gourjon Scientific and Osteopathic Research Department Institut de Formation en Ostéopathie du Grand Avignon403 Rue Marcel DemonqueAvignonFrance Département de recherche clinique Centre hospitalier d’Avignon305A Rue Raoul FollereauAvignonFrance Service de cardiologie Centre hospitalier d’Avignon305A Rue Raoul FollereauAvignonFrance Service de cardiologie Centre Hospitalier du pays d’Aix-PertuisAvenue des Tamaris Aix-en-ProvenceFrance

Heart rate variability(HRV)analysis provides an assessment of cardiac vagal tone and consequently global cardiac health as well as systemic *** systemic diseases such as cancer and during treatments that affect the whole body,like chemotherapy,the vagus nerve activity is low and *** studies focus on using HRV to predict mortality in ***,in cancer patients,systemic alterations substantially increase artifacts during HRV measurement,especially atrial ectopic ***,HRV may be altered by various factors(duration and time of measurement,breathing,drugs,and other confounding factors)that alter each metric in different *** Standard Deviation of all Normal to Normal intervals(SDNN)is the most commonly used metric to evaluate HRV in oncology,but it does not appear to be specific to the cardiac vagal ***,cardiac vagal activity diagnosis and vital prognosis of cancer patients can be *** review presents the main HRV metrics that can be currently used in oncology studies and their links with vagus nerve and *** present the influence of external factors and the required duration and time of *** all these parameters,this review proposes seven key points for an assessment of HRV and cardiac vagal tone in patients with cancer.

关键词： Clinical oncology Heart rate control Vagal nerve stimulation Autonomic nervous system Evaluation methodology

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atypical Hemolytic Uremic Syndrome in a Patient with Acute Promyelocytic Leukemia: A Case Report

引用

Case Reports in Clinical Medicine 2023年第2期12卷 37-43页

作者： Pilar Dutari Tantrantan Leonce Adjoumani marilyne grinand Olivier Lavelle Moglie Le Quintrec Safia Chebrek Department of Oncohematology Henri Duffaut Hospital Center Avignon France Department of Nephrology Henri Duffaut Hospital Center Avignon France Department of Nephrology Dialysis and Renal Transplantation University Hospital of Lapeyronie Montpellier France

Introduction: Acute Promyelocytic Leukemia (APL) is highly associated with hemostasis alterations. The atypical hemolytic uremic syndrome (aHUS) is a rare type of Thrombotic Microangiopathy (TMA) due to an overactivation of the alternative complement pathway. Case Presentation: A 48-years-old woman was diagnosed with APL and achieved molecular remission after induction therapy. During the second consolidation cycle she presented with TMA. She began treatment with plasma exchange plus corticotherapy but due to aggravation of symptoms Eculizumab was initiated. Thrombotic thrombocytopenic purpura, infections and drug toxicity causes were ruled out. There was no evidence of relapse of the APL. Genetic studies of the hereditary anomalies of the alternative complement pathway were negative and the decision of stopping Eculizumab was made. During maintenance therapy for the APL she presented a severe relapse of the aHUS, requiring dialysis. She re-started treatment with Eculizumab with a progressive hematologic recovery and improvement of renal function. She completed APL treatment without relapse of the leukemia for the moment and continues to be treated with Eculizumab. Conclusion: This is the first published case of coexisting aHUS and APL successfully treated with Eculizumab.

关键词： Atypical Hemolytic Uremic Syndrome Acute Promyelocytic Leukemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Human pluripotent stem cells:From biology to cell therapy

引用

World Journal of Stem Cells 2010年第2期2卷 24-33页

作者： Jean-Marie Ramirez marilyne Dijon-grinand Said Assou Sabine Gerbal-Chaloin Samir Hamamah John De Vos INSERM U847MontpellierF 34000France CHU Montpellier Institute for Research in BiotherapyHospital Saint-EloiMontpellierF34000France INSERM U632MontpellierF 34000France University Montpellier1 UFR of MedicineMontpellierF 34000France CHU Montpellier Department of Assisted Reproductive TechnologyHospital Arnaud de VilleneuveMontpellierF 34000France CHU Montpellier Unit for Cellular TherapyHospital Saint-EloiMontpellierF 34000France

Human pluripotent stem cells(PSCs),encompassing embryonic stem cells and induced pluripotent stem cells,proliferate extensively and differentiate into virtually any desired cell *** endow regenerative medicine with an unlimited source of replacement cells suitable for human *** hurdles must be carefully addressed in PSC research before these theoretical possibilities are translated into clinical *** obstacles are:(1) cell proliferation;(2) cell differentiation;(3) genetic integrity;(4) allogenicity;and(5) ethical *** discuss these issues and underline the fact that the answers to these questions lie in a better understanding of the biology of *** contribute to this aim,we have developed a free online expression atlas,Amazonia!,that displays for each human gene a virtual northern blot for PSC samples and adult tissues(http://***).

关键词： Pluripotent stem cells Embryonic stem cells Therapeutics Cell reprogramming Cell proliferation Cell differentiation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：