检索结果-南通市图书馆

Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors

Journal of Molecular Cell Biology 2020年第3期12卷 202-215页

作者： Augustin Le Naour Melissa Prat Benolt Thibault Renaud Mével Léa Lemaitre Helene Leray marie-veronique joubert Kimberley Coulson Muriel Golzio Lise Lefevre Eliane Mery Alejandra Martinez Gwénael Ferron Jean-Pierre Delord Agnès Coste Bettina Couderc Institut Claudius Regaud-IUCT Oncopole Universite de ToulouseToulouseFrance INSERM UMR 1037 Cancer Research Center of Toulouse(CRCT)ToulouseFrance UMR 152 Pharma Dev Universite de ToulouseIRDUPSToulouseFrance UMR CNRS 5089 Institut de Pharmacologie et de Biologie Structurale(IPBS)ToulouseFrance

Factors released by surrounding cells such as cancer-associated mesenchymal stromal cells(CA-MSCs)are involved in tumor progression and *** this study,we characterize the mechanisms by which naYve mesenchymal stromal cells(MSCs)can acquire a CA-MSCs *** tumor cells trigger the transformation of MSCs to CA-MSCs by expressing pro-tumoral genes implicated in the chemoresistance of cancer cells,resulting in the secretion of high levels of CXC chemokine receptors 1 and 2(CXCR1/2)ligands such as chemokine(C-X-C motif)ligand 1(CXCL1),CXCL2,and interleukin 8(IL-8).CXCR1/2 ligands can also inhibit the immune response against ovarian tumor ***,through their released factors,CA-MSCs promote the differentiation of monocytes towards M2 macrophages,which favors tumor *** CXCR1/2 receptors are inhibited,these CA-MSC-activated macrophages lose their M2 properties and acquire an anti-tumoral *** ex vivo and in vivo,we used a CXCR1/2 inhibitor to sensitize ovarian tumor cells to carboplatin and circumvent the pro-tumoral effects of *** high concentrations of CXCR1/2 ligands in patients*blood are associated with chemoresistance,CXCR1/2 inhibition could be a potential therapeutic strategy to revert carboplatin resistance.

关键词： chemoresistance macrophages mesenchymal stromal cells ovarian adenocarcinoma chemokines

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ALowFrequencyModel for Acoustic Propagation in a 2D Flow Duct:Numerical Computation

引用

Communications in Computational Physics 2012年第2期11卷 508-524页

作者： Lauris joubert Patrick Joly POEMS CNRS-INRIA-ENSTA UMR 270632 Boulevard Victor75015 ParisFrance POEMS CNRS-INRIA-ENSTAUMR 2706INRIA RocquencourtBP 10578153 Le Chesnay CedexFrance

In this paper we study a low frequency model for acoustic propagation in a 2D flow *** some Mach profile flow,we are able to give a well-posedness *** proof relies on a quasi-explicit expression of the solution which provides us an efficient numerical *** give and comment numerical results for particular linear,tangent and quadratic ***,we give a numerical validation of our asymptotic model.

关键词： Acoustics in flow Galbrun’s equations asymptotic analysis Laplace transform

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Product of the Restrained Domination Numbers of a Graph and Its Complement

引用

Acta Mathematica Sinica,English Series 2014年第3期30卷 445-452页

作者： Johannes H.HATTINGH Ernst J.joubert Department of Mathematics East Carolina University Department of Mathematics University of Johannesburg

Let G=（V,E） be a graph.A set S■V is a restrained dominating set if every vertex in V-S is adjacent to a vertex in S and to a vertex in *** restrained domination number of G,denoted γr（G）,is the smallest cardinality of a restrained dominating set of *** this paper,we show that if G is a graph of order n≥4,then γr（G）γr（G）≤*** also characterize the graphs achieving the upper bound.

关键词： Graph domination restrained domination Nordhaus-Gaddum upper bound

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparison of the VO_(2)Master Pro and Cosmed K5 During Walking,Jogging,and Running

引用

Journal of Science in Sport and Exercise 2022年第2期4卷 119-127页

作者： Alex Toulouse Dustin joubert Gary Oden Patrick R.Davis Department of Kinesiology Sam Houston State UniversityHuntsvilleTXUSA Department of Kinesiology and Health Science Stephen F.Austin UniversityNacogdochesTXUSA

Aim Portable devices that accurately detect the composition of expired gases and changes in VO_(2)open new possibilities in research methodology and *** The purpose of this study was to compare the oxygen consumption(VO_(2))measurements of the VO_(2)Master Pro(VM)to the Cosmed K5(K5)during walking,jogging,and running in field and lab *** Twelve proficient runners,with a current 10 k pace of≥11.29 km/h,performed 3 matched intervals at 3 different speeds(4.82,8.05,11.29 km/h)on a treadmill and on an outdoor *** airflow test was also performed on both devices by pumping air through the devices using a 3 L syringe timed to a metronome at 15,25,and 35 beats/*** The VM did not report walking data for most *** treadmill running,there were significant differences in VO_(2)(47.86±3.94 vs.29.56±4.15 mL/kg/min),ventilation(V_(e))(71 vs.57 mL/min),and tidal volume(TV)(1.89 vs.1.56 L)between the K5 and VM respectively(P<0.05).Outdoor analysis also showed significant differences between devices in VO_(2),V_(e),and TV(P<0.05).The airflow test showed significant differences between the devices in V_(e)and TV(P<0.05).Conclusion These results suggest that there are significant discrepancies between the K5 and the VM,likely due to differ-ences in TV measurement.

关键词： Oxygen consumption Energy expenditure Metabolic cart Comparison

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Green and red Anti-Stokes emission of U^(3+): LaCl_3 produced by infrared laser

引用

原子与分子物理学报 2001年第1期18卷 4-6页

作者： YIN Min DEREN P J joubert M F KRUPA J C University of Science and Technology of China Institute of Low Temperature and Structure Researches. PO Box 937 Universite Claude Bernard Lyon 1 Groupe de Radiochimie Institut de Physique Nucleaire

Anti-Stokes green and red emission from U3+: LaCl3 can be produced by infrared laser excitation at 975.3 nm, 977.7 nm and 979.4 nm at 8K. The upconversion luminescence intensity dependence upon the excitation laser power was measured and analyzed. The results show that depending on the excitation wavelength, the mechanisms responsible for the upconversion process are two-photon absorption and excited-state absorption.

关键词：非燃烧发光三氯化镧晶体红外激光

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evaluation of Fruit Fly （Diptera： Tephritidae） Monitoring Systems on Mango in Limpopo Province, South Africa

引用

Journal of Agricultural Science and Technology(B) 2015年第10期5卷 653-663页

作者： Elsje joubert Tertia Grove Gerhard Booysen South African Subtropical Growers' Association Tzaneen 0850 South Africa Agricultural Research Council Tropical and Subtropical Crops Nelspruit 1200 South Africa Insect Science (Pty) Ltd. Tzaneen 0850 South Africa

Fruit fly species＇ responses to lures are critically important, especially when a single lure might be recommended for the purpose of trapping multiple fruit fly species in commercial fruit orchards. Fruit industries are facing threats from the recent invasion of the oriental fruit fly Bactrocera dorsalis （Hendel） into novel areas in South Africa. The objective of this study was to test the relative efficiency of 13 different trapping systems for fruit fly species in mango orchards in South Africa. Evaluation of the different monitoring systems was conducted during the 2013-2014 mango season in the Vhembe district municipality of Limpopo, South Africa. Four orchards, where Tommy Atkins was cultivated, were used to compare the efficacy of the trapping systems. Trapping data （N = 48 observation incidences per trapping system） were analyzed using a non-parametric ANOVA. Pronounced variation in species attractiveness across the trapping systems was found. The enriched ginger oil （EGO） PherolureTM captured 33.77% of all the Ceratitis spp., while the Invader-lureTM captured 36.47% of the total number of B. dorsalis trapped. Torula yeast pellets are not recommended for fruit fly trapping due to the relative low trap catch numbers and high non-target catches. These results are important and significant for on-farm monitoring strategies, as well as for invasion monitoring systems currently in place to detect the distribution ofB. dorsalis in South Africa.

关键词： Fruit fly lure Diptera Tephritidae monitoring systems mango.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Establishing a Relationship between Coal Quality and the Enrichment of Radionuclides in Coal Combustion Residues

引用

World Journal of Nuclear Science and Technology 2019年第3期9卷 113-126页

作者： Uwais Al Qarni Ahmed Adriaan joubert National Nuclear Regulator Eco-Park Estate Centurion South Africa CIMERA Department of Geology University of Johannesburg Kingsway Campus Auckland Park Johannesburg South Africa

Coal-fired power plants (CFPP) provide approximately 40% of the world’s energy demand. Naturally occurring radioactive materials (NORM) contained in coal become enriched in coal combustion residues as a result of the elimination of carbon during combustion. The fly ash and bottom ash produced from CFPP may be significant sources of exposure to naturally occurring radionuclides for the population near the combustion plant or ash dumps. Despite this fact, very few studies have actually addressed the relationship of the NORM enrichment factors and the quality of coal used. This paper aims to relate the quality of coal to the enrichment factors for the radionuclides of interest (K40, Ra226, Th232 and Po210) in coal combustion residues from three South African CFPP. The data from other CFPP was also taken into account to establish this correlation. The feedstock coal used in these CFPP is typically low quality, with ash content in the range of 25 - 45 wt%. The radionuclides investigated were determined by gamma spectrometry with the exception of Po210, which was determined by alpha spectrometry. The enrichment factors for the radionuclides of K40, Ra226, Th232 and Po210 in the fly ash and bottom ash (except Po210) was found to be directly proportional to the quality of coal. That is when the ash percentage increased (coal quality decreased) the enrichment factor decreased. The Po210 radionuclide in the bottom ash had an enrichment factor less than one. The relationship between coal quality and enrichment factors for the radionuclides of K40, Ra226, Th232 and Po210 in both the fly ash and bottom ash (except Po210 in the bottom ash) was demonstrated by the following mathematical equation: . This equation may be used as a good indication in obtaining an estimate in determining the enrichment of the mentioned radionuclides in coal combustion products such as fly ash and bottom ash.

关键词： Radionuclides Coal Enrichment Factor Coal Quality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

TOWARDS CO_(2) NEUTRAL URBAN PLANNING:Presenting the Rotterdam Energy Approach and Planning(REAP)

引用

Journal of Green Building 2009年第3期4卷 103-112页

作者： Nico Tillie Andy Van Den Dobbelsteen Duzan Doepel Marc joubert Wim De Jager Dave Mayenburg City of Rotterdam dS+V and Department of Building TechnologyFaculty of ArchitectureDelft University of Technology Department of Building Technology Faculty of ArchitectureDelft University of Technology 不详

By the year 2025 Rotterdam aims to have halved its CO_(2) emissions;an ambitious plan that will require a revolution-ary approach to urban *** proactive response to this challenge is an exploratory study of the Hart van Zuid *** interdisciplinary team has investigated how to tackle CO_(2)-issues in a structured *** has resulted in the Rotterdam Energy Approach and Planning(REAP)*** supports initial demand for energy,propagates the use of waste streams and advocates use of renewable energy sources to satisfy the remaining *** can be applied at all levels:individual buildings,clusters of buildings and even whole ***-ing REAP to the Hart van Zuid has shown that this existing area can become CO_(2) *** of all:REAP can be applied everywhere.

关键词： EAP individual satisfy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The power of performance : linking past and present in Hananwa and Lobedu oral literature

引用

2004年

作者： joubert Annekie

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Endoscopy-based management decreases the risk of postoperative recurrences in Crohn's disease

引用

World Journal of Gastroenterology 2016年第21期22卷 5068-5078页

作者： Anne-Laure Boucher Bruno Pereira Stéphanie Decousus Marion Goutte Felix Goutorbe Anne Dubois Johan Gagniere Corinne Borderon Juliette joubert Denis Pezet Michel Dapoigny Pierre J Déchelotte Gilles Bommelaer Anthony Buisson Gastroenterology Department University Hospital Estaing 63000 Clermont-Ferrand France DRCI Biostatistics Unit GM Clermont-Ferrand University and Medical Center 63000 Clermont-Ferrand France Pathology Department University Hospital Estaing 63000 Clermont-Ferrand France Microbes Intestine Inflammation and Susceptibility of the Host UMR 1071 Inserm/Universite d'Auvergne USC-INRA 2018 63000 Clermont-Ferrand France Digestive Surgery Department University Hospital Estaing 63000 Clermont-Ferrand France Pediatrics Department University Hospital Estaing 63000 Clermont-Ferrand France

AIM: To investigate whether an endoscopy-based management could prevent the long-term risk of postoperative ***: From the pathology department database, we retrospectively retrieved the data of all the patients operated on for Crohn’s disease (CD) in our center (1986-2015). Endoscopy-based management was defined as systematic postoperative colonoscopy (median time after surgery = 9.5 mo) in patients with no clinical postoperative recurrence at the time of ***: From 205 patients who underwent surgery, 161 patients (follow-up > 6 mo) were included. Endoscopic postoperative recurrence occurred in 67.6%, 79.7%, and 95.5% of the patients, respectively 5, 10 and 20 years after surgery. The rate of clinical postoperative recurrence was 61.4%, 75.9%, and 92.5% at 5, 10 and 20 years, respectively. The rate of surgical postoperative recurrence was 19.0%, 38.9% and 64.7%, respectively, 5, 10 and 20 years after surgery. In multivariate analysis, previous intestinal resection, prior exposure to anti-TNF therapy before surgery, and fistulizing phenotype (B3) were postoperative risk factors. Previous perianal abscess/fistula (other perianal lesions excluded), were predictive of only symptomatic recurrence. In multivariate analysis, an endoscopy-based management (n = 49/161) prevented clinical (HR = 0.4, 95%CI: 0.25-0.66, P < 0.001) and surgical postoperative recurrence (HR = 0.30, 95%CI: 0.13-0.70, P = 0.006).CONCLUSION: Endoscopy-based management should be recommended in all CD patients within the first year after surgery as it highly decreases the long-term risk of clinical recurrence and reoperation.

关键词： Crohn’ s disease Postoperative recurrence Endoscopy Prevalence Risk factors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：