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Automated brain tumor segmentation on multi-modal MR image using SegNet

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Computational Visual Media 2019年第2期5卷 209-219页

作者： Salma Alqazzaz Xianfang Sun Xin Yang len Nokes School of Engineering Cardiff UniversityCardiffCF24 3AAUK Department of Physics College of Science for WomenBaghdad UniversityBaghdadIraq School of Computer Science and Informatics Cardiff UniversityCardiffCF24 3AAUK

The potential of improving disease detection and treatment planning comes with accurate and fully automatic algorithms for brain tumor ***, a type of brain tumor, can appear at different locations with different shapes and sizes. Manual segmentation of brain tumor regions is not only timeconsuming but also prone to human error, and its performance depends on pathologists’ experience. In this paper, we tackle this problem by applying a fully convolutional neural network SegNet to 3 D data sets for four MRI modalities(Flair, T1, T1 ce, and T2)for automated segmentation of brain tumor and subtumor parts, including necrosis, edema, and enhancing tumor. To further improve tumor segmentation, the four separately trained SegNet models are integrated by post-processing to produce four maximum feature maps by fusing the machine-learned feature maps from the fully convolutional layers of each trained model. The maximum feature maps and the pixel intensity values of the original MRI modalities are combined to encode interesting information into a feature *** the combined feature as input, a decision tree(DT) is used to classify the MRI voxels into different tumor parts and healthy brain tissue. Evaluating the proposed algorithm on the dataset provided by the Brain Tumor Segmentation 2017(BraTS 2017)challenge, we achieved F-measure scores of 0.85, 0.81,and 0.79 for whole tumor, tumor core, and enhancing tumor, *** results demonstrate that using SegNet models with 3 D MRI datasets and integrating the four maximum feature maps with pixel intensity values of the original MRI modalities has potential to perform well on brain tumor segmentation.

关键词： brain tumor segmentation multi-modal MRI convolutional neural networks fully convolutional networks decision tree

The Development of Advanced Polymer Composites in Civil Engineering An Overview of the European Scene

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工业建筑 2004年第Z1期34卷 -页

作者： len Hollaway School of Engineering - Civil Engineering University of Surrey Guildford Surrey UK.

In the construction industry there has always been a mismatch between the research investment and construction expenditure and this has lead the industry to proceed on a scale with an inadequate understanding of many aspects of construction, such as, deterioration mechanism for structures that has often meant that due allowance has not been made for practical repair and ***, notwithstanding this situation there have been encouraging signs that within the last twenty years the transition from the conventional materials to the more advanced materials is being spear-headed by the construction industry where over 30％ of all polymers produced are now utilised in that industry.

关键词： Civil Engineering construction industry advanced materials

Synthesis of a novel uridine analogue and its use in attempts to form new cyclonucleosides using ring-closing metathesis

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Science China Chemistry 2010年第9期53卷 1932-1936页

作者： MONDON Martine len Christophe UMR 6514 Université de Poitiers CNRS Synthèse et Réactivité des Substances Naturelles EA4297 Université de Technologie de Compiègne UTC-Ecole Supérieure de Chimie Organique et Minérale ESCOM

One novel nucleoside analogue having a hex-5-enyl group and an allyl group in the 5'-C and 3-N position was synthesized regioand diastereoselectively from D-glucose in twelve *** order to reach a particular conformation of nucleosides the nucleoside formation of restricted cyclonucleoside analogues was studied via Ring-Closing Metathesis.

关键词： nucleoside restrictedconformation metathesis

Weakly Admissible Meshes and Discrete Extremal Sets

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Numerical Mathematics(Theory,Methods and Applications) 2011年第1期4卷 1-12页

作者： len Bos Stefano De Marchi Alvise Sommariva Marco Vianello Department of Computer Science University of VeronaStrada Le Grazie 15-37134 VeronaItaly Department of Pure and Applied Mathematics University of PaduaVia Trieste 63-35121 PaduaItaly

We present a brief survey on (Weakly) Admissible Meshes and corresponding Discrete Extremal Sets, namely Approximate Fekete Points and Discrete Leja *** provide new computational tools for polynomial least squares and interpolationon multidimensional compact sets, with different applications such as numerical cubature, digital filtering, spectral and high-order methods for PDEs.

关键词： Weakly admissible meshes Approximate Fekete points Discrete Leja points

Comparison of dietary intakes of Canadian Armed Forces personnel consuming field rations in acute hot, cold, and temperate conditions with standardized infantry

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Military Medical Research 2020年第1期7卷 77-92页

作者： Mavra Ahmed Iva Mandic Wendy Lou len Goodman Ira Jacobs Mary R.L’Abbé Department of Nutritional Sciences Faculty of MedicineUniversity of TorontoMedical Science Building1 King's College CircleRoom 5368TorontoOntario M5S 1A8Canada Faculty of Kinesiology and Physical Education University of TorontoToronto M5S 2W6Canada Dalla Lana School of Public Health University of TorontoToronto M5T 3M2Canada Defence Research and Development Canada-Toronto Research Centre Toronto M3K 2C9Canada

Background:Dietary Reference Intakes are used to guide the energy intake of the Canadian Armed Forces(CAF)field rations provided to military personnel deployed for training or ***,the high energy expenditures likely to occur under harsh environmental/metabolically challenging deployment conditions may not be adequately *** study examined the Ad libitum energy and nutrient intakes of CAF personnel(n=18)consuming field rations in a resting thermoneutral environment and during a day of standardized strenuous infantry activities at varying environmental ***:Dietary intake was assessed using a measured food intake/food waste method during the experimental treatment and for 6 h after *** treatments were administered in a randomized counterbalanced design:exercise(as standardized infantry activities)in the heat(30℃),exercise in the cold(–10℃),exercise in temperate thermoneutral(21℃)air temperatures and a resting(sedentary)trial(21℃).Results:The average Ad libitum consumption of field rations was 70%of the provided total energy(2776±99 kcal/8 h)during all *** with an acute challenge of increased energy expenditure and temperature stress in the simulated field conditions,participants’energy intakes(1985±747 kcal/8 h)under hot,cold and temperate treatments did not differ from energy intake during the sedentary condition(1920±640 kcal/8 h).Participants’energy intakes(1009±527 kcal/6 h)did not increase during the 6 h posttreatment period when the stresses of the strenuous physical activities and the harsh environmental temperatures had ***:These results should be considered when planning the provision of field rations for CAF personnel expected to be engaged in strenuous physical activities with prolonged exposure to temperature extremes.

关键词： Dietary assessment Nutrient intakes Military personnel Physical activity Temperature extremes Field rations

A New Isoflavone Glucoside from Astragalus membranaceus

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Chinese Chemical Letters 1998年第6期9卷 537-538页

作者： Cao, ZZ Cao, Y Yi, YJ Wu, YP len, ZK Li, D Owen, NL Jiangsu Province Inst Mat Med Nanjing 210009 Peoples R China Brigham Young Univ Dept Chem & Biochem Provo UT 84602 USA

A new isoflavone glucoside, 3'-methoxy-5'-hydroxy-isoflavone-7-O-beta-D-glucoside, was isolated from the roots of Astragalus membranaceus and its structure was elucidated by spectroscopic data.

关键词： Astragalus membranaceus isoflavone 3 '-methoxy-5 '-hydroxy-isoflavone-7-O-beta-D-glucoside

Is increased red cell distribution width an indicating marker of nonalcoholic steatohepatitis and fibrotic stage?

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World Journal of Gastroenterology 2013年第42期19卷 7412-7418页

作者： Mustafa Cengiz burcu Aslan Candir Güldal Yilmaz Gülen Akyol Seren Ozenirler Department of Gastroenterology Gazi University Faculty of Medicine06500 AnkaraTurkey Department of Internal Medicine Gazi University Faculty of Medicine06500 AnkaraTurkey Department of Pathology Gazi University Faculty of Medicine06500 AnkaraTurkey

AIM:To evaluate the red cell distribution width(RDW)as an indicator of the presence of non-alcoholic steatohepatitis(NASH)and its association with fibrotic ***:A retrospective study was carried out that included sixty-two biopsy proven NASH,32 simple steatosis patients and 30 healthy *** correlation between the clinical and histopathological features of NASH patients and RDW values was *** fibrosis scores were measured using a 0 to 4 point scale and were divided in to two groups;fibrosis scores0-1 were termed mild and fibrosis scores 2-4 were termed advanced *** values were compared between NASH,simple steatosis and healthy *** and multivariate analyses were performed to evaluate the independent predicting factors for the presence of liver fibrosis caused by ***:Patients with NASH had higher RDW values compared with simple steatosis and healthy control groups[14.28%±0.25%vs 13.37%±0.12%,12.96%±0.14%(P<0.01),respectively].Patients with advanced fibrosis had higher RDW values than the mild fibrosis group(15.86%±0.4%vs 13.63%±0.67%,P<0.01,respectively).RDW also correlated with fibrotic scores(r=0.579 andP<0.01).The variables that were significant in the univariate analysis were evaluated in multivariate logistic regression analysis,and RDW was an independent predicting factor of NASH(OR=1.75,95%CI:1.129-2.711,P<0.05).CONCLUSION:RDW a new non-invasive marker that can be used to demonstrate the presence of NASH and indicate advanced fibrotic scores.

关键词： Non-alcoholic steatohepatitis Liver fibrosis Red cell distribution width Simple steatosis Noninvasive marker Liver biopsy

Multimodal Literacy in a New Era of Educational Technology:Comparing Points of View in Animations of Children's and Adult Literature

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ECNU Review of Education 2024年第2期7卷 384-405页

作者： len Unsworth Institute for Learning Sciences and Teacher Education Australian Catholic UniversityNorth Sydney CampusLevel 27Mount StNorth SydneyPo Box 968North SydneyNsW 2059Australia

Purpose The paper shows the interpretive impact of different constructions of the point of view available to the reader/viewer in book and animated movie versions of a children's picture book,a novel for pre-adolescents/early teenagers,and a graphic novel for adolescents and ***/Approach/Methods Excerpts from book and animated movie versions of the same story are compared using multimodal analysis of interpersonal meaning to show how the reader/viewer is positioned in relation to the characters in each version,complemented by analyses of ideational meaning to show the effect of point of view on interpretive *** Focusing mainly on multimodal construction of point of view,the analyses show how interpretive possibilities of ostensibly the same story are significantly reconfigured in animated adaptations compared with book versions even when the verbal narrative remains substantially ***/Value The study shows that it is crucial to students’critical appreciation of,and their creative contribution to,their evolving digital literary culture that in this new era of educational technology,attention in literacy and literary education focuses on developing understandings of digital multimodal narrative art,and that animated movie adaptations are not presented pedagogically as isomorphic with,or simply adjunct to,corresponding book versions.

关键词： Animation children's literature multimodality point of view

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地理信息系统（GIS）在地质学中的应用

地学前缘 1995年第2期2卷 236-243页

作者：李晓池 burc.,SE 南非共和国开普敦大学地质系

地理信息系统（ＧＩＳ）在最近５～８年中已普遍应用，它是在计算机上储存、编组和分析空间信息的系统。ＧＩＳ研究项目利用ＰＣＡＲＣ／ＩＮＦＯ软件处理地质和地理信息。自１９６０年以来，从南非海岸收集了大量海洋地质和地球物理信... 详细信息

地理信息系统（ＧＩＳ）在最近５～８年中已普遍应用，它是在计算机上储存、编组和分析空间信息的系统。ＧＩＳ研究项目利用ＰＣＡＲＣ／ＩＮＦＯ软件处理地质和地理信息。自１９６０年以来，从南非海岸收集了大量海洋地质和地球物理信息，包括地震资料、声纳扫描、测深、磁法和重力记录，以及大量海底沉积物和岩石标本。这些资料对环境保护和矿产资源勘查方面的未来科学研究很有价值。目前这些信息难以利用，因为分析结果尚未能以一种方式储存可以直接相容。我们正在建立数据库，使用“ｄＢＡＳＥⅣ”和“ＰＣＡＲＣ／ＩＮＦＯ”以科学的、系统的方式连接各类地质和地球物理数据，从而提供利用这些信息的简单方便的方法。本文展示了南非西南海岸海洋沉积物分析的初步结果。扩大和改进数据库的研究正在进行。文中探讨了利用ＧＩＳ处理一般地质信息的可能性和优势。

关键词： GIS 地质数据数据库地质学