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FactSage Thermodynamic Database for Steelmaking Refractory Research

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China's Refractories 2015年第1期24卷 15-21页

作者： In-Ho JUNG marie-aline van ende Mun-Kyu CHO Zhanmin CAO Mining and Materials Engineering McGill University Research Institute of Industrial Science and Technology School of Metallurgical and Ecological Engineering University of Science and Technology Beijing

Thermodynamic databases are very useful to analyze the complex chemical reactions happening in high temperature material processes. An accurate thermodynamic database based on physically sound thermodynamic models can provide thermodynamic calculations of useful phase diagrams and comprehensive chemical reactions related to refractory corrosion in steelmaking processes. In this study,the FactS age thermodynamic database,one of the most comprehensive thermodynamic databases for oxide systems among other commercial software,is reviewed in particular for the steelmaking refractory research,and several applications to refractory corrosion are presented.

关键词： thermodynamic database CALPHAD FactSage phase diagram corrosion steelmaking

二次精炼过程中Al—Ti氧化物夹杂的形成和演变

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现代冶金（内蒙古） 2011年第4期 16-22,59页

作者： marie-aline van ende[比利时] 张怀军（译）唐建平（校）

本文在感应炉中通过定氧探头和所取钢样，研究了铝脱氧和RH脱气处理过程中钛合金化工艺，二次精炼温度控制在1600—1650℃，气源采用氩气。采用热力学计算讨论了在部分铝脱氧和添加钛过程中夹杂物的形成以及通过二次添加铝减少Al-Ti-O... 详细信息

本文在感应炉中通过定氧探头和所取钢样，研究了铝脱氧和RH脱气处理过程中钛合金化工艺，二次精炼温度控制在1600—1650℃，气源采用氩气。采用热力学计算讨论了在部分铝脱氧和添加钛过程中夹杂物的形成以及通过二次添加铝减少Al-Ti-O夹杂物。对夹杂物以及夹杂物和钢水两者之间的组成关系给出了明确说明。试验结果和计算结果表明：为了阻止在钢水中形成钛氧化物，在加入钛合金之前，主要控制钢水中的[Al]保持大约200ppm，在合金化过程中，为了使钛损失最小，钛含量应该保持500ppm左右。

关键词： IF钢 Al-Ti脱氧钛合金 Al-Ti-O夹杂物 Fe—Al-Ti-O平衡相图

The effect of host plants on genotype variability in fitness and honeydew composition of Aphis fabae

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Insect Science 2017年第5期24卷 781-788页

作者： Sharon Schillewaert Amelie vantaux Wim van den ende Tom Wenseleers Laboratory of Socioecology and Social Evolution Biology Department Zoological Institute University of Leuven Leuven Belgium Institut Pasteur du Cambodge Unite d'Epidemiologie Moleculaire du Paludisme Phnom Penh Cambodia Laboratory of Molecular Plant Biology Biology Department University of Leuven Leuven Belgium

Aphid species can be polyphagous, feeding on multiple host plants across genera. As host plant species can have large variation in their phloem composition, this can affect aphid fitness and honeydew composition. Previous research showed significant intraspecific genotype variation in the composition of the honeydew carbohydrates of the black bean aphid Aphis fabae, with the ant attractant trisaccharide melezitose showing especially large variation across different genotypes. In this study, we test if variation in melezitose and carbohydrate composition of aphid honeydew could be linked to the adap- tation of specific aphid genotypes to particular host plants. To this end, 4 high and 5 low melezitose secreting genotypes of the black bean aphid Aphisfabae were reared on 4 com- mon host plants： broad bean, goosefoot, beet, and poppy. The carbohydrate composition, and in particular melezitose secretion, showed important aphid genotype and host plant in- teractions, with some genotypes being high melezitose secreting on 1 host plant but not on another. However, the interaction effects were not paralleled in the fitness measurements, even though there were significant differences in the average fitness across the different host plants. On the whole, this study demonstrates that aphid honeydew composition is influenced by complex herbivore-plant interactions. We discuss the relevance of these findings in the context of ant-aphid mutualisms and adaptive specialization in aphids.

关键词： aphids Aphis fabae ecological specialization fitness honeydew hostplants Melezitose polyphagous

Diversity and delimitation of Rhizopus microsporus

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Fungal Diversity 2014年第1期64卷 145-163页

作者： Somayeh Dolatabadi Grit Walther A.H.G.Gerrits van den ende G.S.de Hoog CBS-KNAW Fungal Biodiversity Centre P.O.Box 851673508 AD UtrechtThe Netherlands Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamThe Netherlands Institute of Microbiology Department of Microbiology and Molecular BiologyUniversity of JenaJenaGermany Leibniz-Institute for Natural Product Research and Infection Biology-Hans-Knöll-Institute Jena Microbial Resource CollectionJenaGermany Research Center for Medical Mycology Peking University Health Science CenterBeijingChina Sun Yat-sen Memorial Hospital Sun Yat-sen UniversityGuangzhouChina Shanghai Institute of Medical Mycology Changzheng HospitalSecond Military Medical UniversityShanghaiChina

Rhizopus microsporus has been used for centuries in the production of oriental fermented foods,but the species is also known as a toxin producer and from severe human *** study the diversity and species delimitation of Rhizopus microsporus,48 isolates from the reference collection of the CBS-KNAW Fungal Biodiversity Centre,comprising nine environmental,ten clinical,and 23 foodborne strains,in addition to six strains from unknown sources and representing all existing varieties of the species,were *** diversity was based on the internal transcribed spacer(ITS),and on a part of the actin(ACT)and translation elongation factor 1-α(TEF)*** in physiological properties were assessed including temperature *** morphology was studied,mating type tests were performed,and MALDI-ToF profiles were *** and food-associated strains as well as members of different varieties mated successfully and consequently they belong to a single biological *** differences did not match with any other parameter *** on these results the varieties of Rhizopus microsporus are reduced to synonyms.

关键词： Rhizopus microsporus Phylogeny Taxonomy Physiology MALDI-ToF Mating type Foodborne fungi Medical mycology Sporulation

Sucrose Induction of Anthocyanin Biosynthesis Mediated by DELLA

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Molecular Plant 2014年第3期7卷 570-572页

作者： Yi Li Wire van den ende Filip Rolland Laboratory of Molecular Plant Biology KU Leuven Department of Biology Kasteelpark Arenberg 31 B-3001 Leuven Belgium

Dear Editor, While they affect all aspects of plant life, the exact molecu- lar mechanisms involved in sugar sensing and signaling are still mostly unknown. However, using the induction of antho- cyanin biosynthesis as a convenient readout and tool, the DELLA proteins can be identified as key positive regulators in sucrose-specific signaling and a point of integration of diverse metabolic and hormonal signals.

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Artificial intelligence for characterization of diminutive colorectal polyps:A feasibility study comparing two computer-aided diagnosis systems

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Artificial Intelligence in Gastrointestinal Endoscopy 2024年第1期5卷 11-22页

作者： Quirine Eunice Wennie van der Zander Ramon M Schreuder Ayla Thijssen Carolus H J Kusters Nikoo Dehghani Thom Scheeve Bjorn Winkens Mirjam C M van der ende-van Loon Peter H N de With Fons van der Sommen Ad A M Masclee Erik J Schoon Department of Gastroenterology and Hepatology Maastricht University Medical CenterMaastricht 6202 AZNetherlands GROW School for Oncology and ReproductionMaastricht UniversityMaastricht 6200 MDNetherlands Division of Gastroenterology and Hepatology Catharina Hospital EindhovenEindhoven 5602 ZANetherlands Department of Electrical Engineering Eindhoven University of TechnologyEindhoven 5600 MBNetherlands Department of Methodology and Statistics Maastricht UniversityPostbus 6166200 MD MaastrichtNetherlands School for Public Health and Primary Care Maastricht UniversityMaastricht 6200 MDNetherlands

BACKGROUND Artificial intelligence(AI)has potential in the optical diagnosis of colorectal *** To evaluate the feasibility of the real-time use of the computer-aided diagnosis system(CADx)AI for ColoRectal Polyps(AI4CRP)for the optical diagnosis of diminutive colorectal polyps and to compare the performance with CAD EYE^(TM)(Fujifilm,Tokyo,Japan).CADx influence on the optical diagnosis of an expert endoscopist was also *** AI4CRP was developed in-house and CAD EYE was proprietary software provided by *** CADxsystems exploit convolutional neural *** polyps were characterized as benign or premalignant and histopathology was used as gold ***4CRP provided an objective assessment of its characterization by presenting a calibrated confidence characterization value(range 0.0-1.0).A predefined cut-off value of 0.6 was set with values0.76).Self-critical AI4CRP’s diagnostic performances excluded low confidence *** AI4CRP use was feasible and performed on 30 patients with 51 colorectal ***-critical AI4CRP,excluding 14 low confidence characterizations[27.5%(14/51)],had a diagnostic accuracy of 89.2%,sensitivity of 89.7%,and specificity of 87.5%,which was higher compared to *** EYE had a 83.7%diagnostic accuracy,74.2%sensitivity,and 100.0%*** performances of the endoscopist alone(before AI)increased nonsignificantly after reviewing the CADx characterizations of both AI4CRP and CAD EYE(AI-assisted endoscopist).Diagnostic performances of the AI-assisted endoscopist were higher compared to both CADx-systems,except for specificity for which CAD EYE performed *** Real-time use of AI4CRP was *** confidence values provided by a CADx is novel and self-critical AI4CRP sho

关键词： Artificial intelligence Colorectal polyp characterization Computer aided diagnosis Diminutive colorectal polyps Optical diagnosis Self-critical artificial intelligence

Multilocus analysis of the Exophiala jeanselmei clade containing black yeasts involved in opportunistic disease in humans

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Fungal Diversity 2014年第2期65卷 3-16页

作者： Jingsi Zeng Peiying Feng A.H.G.Gerrits van den ende Liyan Xi M.J.Harrak G.S.de Hoog Centraalbureau voor Schimmelcultures KNAW Fungal Biodiversity Centre P.O.Box 851673508 AD Utrechtthe Netherlands Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamthe Netherlands Department of Dermatology and Venereology Union HospitalTongji Medical CollegeHuazhong Science and Technology UniversityWuhanChina Third Affiliated Hospital Sun Yat-sen UniversityGuangzhouChina Sun Yat-sen Memorial Hospital Sun Yat-sen UniversityGuangzhouChina Peking University Health Science Center Research Center for Medical MycologyBeijingChina Shanghai Institute of Medical Mycology Changzheng HospitalSecond Military Medical UniversityShanghaiChina

To confirm species delimitations in the‘jeanselmeiclade’in the Chaetothyriales,four independent markers were analysed,and phylogenetic trees were reconstructed using different *** isolation within the complex and reproductive modes in the species involved were determined,in order to explore specific borderlines using Genealogical Concordance Phylogenetic Species Recognition(GCPSR).Sequences of the Internal Transcribed Spacer(ITS),partial Translation Elongation Factor 1-α(TEF1),β-Tubulin(BT2),and Actin(ACT1)genes were analysed for a set of 81 *** reconstruction was performed using neighbour-joining(NJ),maximum parsimony(MP),maximum likelihood(ML)and Bayesian analysis(BA)to evaluate the concordance of topologies obtained under different optimization *** among lineages was detected by Partition Homogeneity Test(PHT).Most Exophiala species analysed in this study seemed to be preponderantly clonal.A group of species around Exophiala spinifera showed a tendency toward human pathogenicity,whereas species around *** were often associated with environments rich in *** the tree topologies were not completely identical when different algorithms were used,the four gene lineages were nearly congruent and the trees of the combined multilocus data set did not provide more phylogenetic information than those of separate data *** data are sufficient for identification of species in the‘jeanselmei-clade’.

关键词： Black yeasts Clonality Exophiala ITS diagnostics Phylogeny

Taxonomy of Ochroconis, genus including opportunistic pathogens on humans and animals

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Fungal Diversity 2014年第2期65卷 89-126页

作者： K.Samerpitak E.van der Linde H.-J.Choi A.H.G.Gerrits van den ende M.Machouart C.Gueidan G.S.de Hoog CBS-KNAW Fungal Biodiversity Centre UtrechtThe Netherlands Department of Microbiology Faculty of MedicineKhon Kaen UniversityKhon KaenThailand Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamThe Netherlands Mycology Unit Biosystematics ProgrammePlant Protection Research InstituteAgricultural Research CouncilPretoriaSouth Africa Evangelisches und Johanniter Klinikum Niederrhein DuisburgGermany Service de Parasitologie-Mycologie CHU de BraboisVandœuvre-lès-NancyFrance Department Life Sciences Division of Microbial&Genomic DiversityNatural History MuseumLondonUK Peking University Health Science Center Research Center for Medical MycologyBeijingChina Sun-Yat-sen Memorial Hospital Sun Yat-sen UniversityGuangzhouChina Second Medical Military University ShanghaiChina

The genus Ochroconis(Sympoventuriaceae,Venturiales)is revised and currently contains 13 species for which the phylogenetic position has been determined using multilocus *** older generic name Scolecobasidium is considered to be of doubtful identity because the type specimen is *** the Ochroconis lineage,phylogenetic distances of all markers analyzed are exceptionally large,both between and within species.A new genus Verruconis is proposed for the neurotropic opportunist Ochroconis *** accepted within the lineages are keyed out on the basis of phenotypic *** ecological traits within each species are *** species are thermophilic and one of them is an important agent of infection in the brain,while Ochroconis is mesophilic,several species causing infections in cold-blooded animals.

关键词： Taxonomy Ecology Thermophilic fungi Human infection Avian pathogen Fish pathogen Neurotropism

Cyphellophora and its relatives in Phialophora: biodiversity and possible role in human infection

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Fungal Diversity 2014年第2期65卷 17-45页

作者： Peiying Feng Qiaoyun Lu M.J.Najafzadeh A.H.G.Gerrits van den ende Jiufeng Sun Ruoyu Li Liyan Xi V.A.Vicente Wei Lai Chun Lu G.S.de Hoog Third Affiliated Hospital Sun Yat-sen UniversityGuangzhouChina Centraalbureau voor Schimmelcultures KNAW Fungal Biodiversity CentreP.O.Box 851673508 AD Utrechtthe Netherlands Xiangyang Central Hospital XiangyangChina Peking University Health Science Center Research Center for Medical MycologyBeijingChina Department of Parasitology and Mycology and Cancer Molecular Pathology Research CenterGhaem HospitalSchool of MedicineMashhad University of Medical SciencesMashhadIran Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamthe Netherlands Key Laboratory of Tropical Disease Control Department of ParasitologyZhongshan School of MedicineSun Yat-sen UniversityGuangzhouChina Sun Yat-sen Memorial Hospital Sun Yat-sen UniversityGuangzhouChina Department of Basic Pathology Federal University of ParanáCuritibaPRBrazil

Cyphellophora is a genus of black yeast-like fungi characterised by having simple phialides with multiseptate,curved *** from SSU and LSU data,Cyphellophora was found to be located in a well-supported clade within the Chaetothyriales comprising a number of species occurring on human skin and *** is phylogenetically close to Phialophora europaea,*** and ***,though morphologically these species produce singlecelled phialoconidia rather than multiseptate *** suttonii and *** have dark colonies and phylogenetically fit in with Cyphellophora;the type species of Pseudomicrodochium,***,has similar,septate conidia but has a hyaline *** the present study,multilocus phylogenetic analyses were combined with morphology and *** of the internal transcribed spacer region,the DNA dependent RNA polymerase II largest subunit and the partial beta tubulin gene were analysed for a set of 30 *** novel species,Cyphellophora pauciseptata and Phialophora ambigua were *** eucalypti was reduced to synonymy of *** role of the studied fungi between colonization and infection of human skin was *** virulence factors for these black yeast-like fungi were hypothesized to be the ability to assimilate monoaromatic hydrocarbons,to produce melanin pigments,and to tolerate the temperature of epidermal human skin.

关键词： Black yeasts Chaetothyriales Cyphellophora Phialophora Superficial infection Taxonomy