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Strawberry (Fragaria spp.): Cultivation, Production, Consumption, and Marketing in Cameroon

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Agricultural Sciences（农业科学） 2024年第4期 449页

作者： Djeuani Astride Carole Moutamal Djem Rose Theophine Derricka Mbouobda Hermann Désiré Abdoulaye Souaibou Meliga Essimi Célestine Bouopda Nono Joël Anafack Donasson Dioril Messouang bernard Didier Ndongo III Boris Charlen Kaffo Emmanuel Kamga Fossouo Anselme Xavier Tiki Antoine marie Kevin Nyimiebolo Bengono Audrey Maguy Manuela Diobe Motassy Adounga Samuel Brice Amama Amama Benjamin Nshanji Jones Panguepko Fendju Christophe Nzie Oussena Nguetrapouna Issofa Mpon Ikoyin Linda NKouéya Christelle Ladone Amang Amang A.Ziem Niemenak Nicolas

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拉·维莱特公园

城市环境设计 2016年第1期 54-65页

作者： bernard Tschumi Luca Merlini Alexandra Villegas Luca Pagnamenta Jon Olsen Jean-Fran?ois Erhel Ursula Kurz Christian Biecher marie-Line Luquet Neil Porter Steve McAdam Jean-Pierre Nourry Didier Pasquier Renzo Bader

1983年,伯纳德·屈米建筑师事务所从470支团队里脱颖而出,赢得了巴黎拉·维莱特公园国际设计竞赛。该项目同新法国国家图书馆、卢浮宫金字塔、拉德芳斯新凯旋门和阿拉伯世界研究中心等项目一样,是当时法国政府主持的几大工程之一。那次... 详细信息

1983年,伯纳德·屈米建筑师事务所从470支团队里脱颖而出,赢得了巴黎拉·维莱特公园国际设计竞赛。该项目同新法国国家图书馆、卢浮宫金字塔、拉德芳斯新凯旋门和阿拉伯世界研究中心等项目一样,是当时法国政府主持的几大工程之一。那次设计竞赛的目标是表达时代愿景,推动项目所处的巴黎关键区域未来经济和文化的发展。

关键词：拉·维莱特公园巴黎法国设计竞赛

Differential Diagnosis Difficulty between Biliary Cystadenoma and Cystaadenocarcinoma of the Liver: A Case Report

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Open Journal of Gastroenterology（肠胃病学期刊） 2023年第1期

作者： Alioune Badara Fall marieme Polele Fall Salamata Diallo marie Louise Bassene Alsine Yauck Coumba Cisse Tene sidibe

Subclinical proximal tubulopathy in hepatitis B:The roles of nucleot(s)ide analogue treatment and the hepatitis B virus

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World Journal of Hepatology 2020年第12期12卷 1326-1340页

作者： Anais Brayette marie Essig Paul Carrier Marilyne Debette-Gratien Anais Labrunie Sophie Alain Marianne Maynard Nathalie Ganne-Carrie Eric Nguyen-Khac Pauline Pinet Victor De Ledinghen Christophe Renou Philippe Mathurin Claire Vanlemmens Vincent Di Martino Anne Gervais Juliette Foucher Fouchard-Hubert Isabelle Julien Vergniol Isabelle Hourmand-Ollivier Daniel Cohen Xavier Duval Thierry Poynard Marc Bardou Armand Abergel Manh-Thong Dao Thierry Thevenot Jean-Baptiste Hiriart Valerie Canva Guillaume Lassailly Christine Aurières Nathalie Boyer Dominique Thabut Pierre-Henri bernard Matthieu Schnee Dominique Larrey Bertrand Hanslik Severine Hommel Jeremie Jacques Veronique Loustaud-Ratti U1248 INSERM Department of Hepatology and GastroenterologyUniv.LimogesCHU LimogesLimoges F-87000France U1248 INSERM Department of Nephrology and TransplantationCHU LimogesLimoges F-87000France Department of Center of Epidemiology Biostatistics and Research MethodologyCHU LimogesLimoges F-87000France U1092 INSERM Department of VirologyCHU LimogesLimoges F-87000France Department of Hepatology Croix-Rousse University Hospital of LyonLyon 69004France Department of Hepatology Jean Verdier University Hospital of BondyBondy 93140France Department of Hepato-Gastroenterology Amiens University HospitalAmiens 80054France Department of Infectious Diseases CHU LimogesLimoges F-87000France Department of Hepatology Haut Leveque HospitalBordeaux University HospitalPessac 33604France Department of Gastroenterology Hyeres HospitalHyeres 83407France Department of Hepato-Gastroenterology Claude Huriez University HospitalLille 59037France Department of Hepatology Jean Minjoz University HospitalBesançon 25030France Department of Infectious Diseases Bichat University HospitalParis 75018France Department of Hepatology University Hospital of AngersAngers 49933France Department of Hepato-Gastroenterology and Nutrition University Hospital of CaenCaen 14033France Department of General Medecine University Hospital of CaenCaen 14000France Department of Hepatology La Pitié-Salpêtrière University HospitalParis 75651France Department of Hepatology and Gastroenterology Dijon University HospitalDijon 21079France Department of Hepatology and Gastroenterology Estaing University HospitalClermont Ferrand 63003France Department of Hepatology Beaujon University HospitalClichy 92110France Department of Hepatology Saint-AndréUniversity HospitalBordeaux 33000France Department of Hepatology and Gastroenterology La Roche-Sur-Yon Hospital CenterLa Roche-Sur-Yon 85000France Department of Hepatology and Gastroenterology University Hospital of MontpellierMontpellier 34295France Department of Addictology Hospita

BACKGROUND The recommended monitoring tools for evaluating nucleot(s)ide analogue renal toxicity,such as estimated glomerular filtration rate(eGFR)and phosphatemia,are late markers of proximal *** early markers are available,but no consensus exists on their *** To determine the 24 mo prevalence of subclinical proximal tubulopathy(SPT),as defined with early biomarkers,in treated vs untreated hepatitis B virus(HBV)-monoinfected *** A prospective,non-randomized,multicenter study of HBV-monoinfected patients with a low number of renal comorbidities was *** patients were separated into three groups:Naïve,starting entecavir(ETV)treatment,or starting tenofovir disoproxil(TDF)*** on the early markers of SPT,the eGFR and phosphatemia,were collected *** was defined as a maximal tubular reabsorption of phosphate/eGFR below 0.8 mmoL/L and/or uric acid fractional excretion above 10%.The prevalence and cumulative incidence of SPT at month 24(M24)were *** data were analyzed using analyses of variance or Kruskal-Wallis tests,whereas chi-squared or Fisher’s exact tests were used to analyze qualitative *** analyses were used to adjust for any potential confounding *** Of the 196 patients analyzed,138(84 naïve,28 starting ETV,and 26 starting TDF)had no SPT at *** M24,the prevalence of SPT was not statistically different between naïve and either treated group(21.1%vs 30.7%,P<0.42 and 50.0%vs 30.7%,P=0.32 for ETV and TDF,respectively);no patient had an eGFR lower than 50 mL/min/1.73 m²or phosphatemia less than 0.48 mmoL/*** the multivariate analysis,no explanatory variables were identified after *** cumulative incidence of SPT over 24 mo(25.5%,13.3%,and 52.9%in the naïve,ETV,and TDF groups,respectively)tended to be higher in the TDF group vs the naïve group(hazard ratio:2.283,P=0.05).SPT-free survival at M24 was 57.6%,68.8%,and 23.5%for the naïve,ETV,and TD

关键词： Hepatitis B virus Proximal tubulopathy Biomarkers Renal insufficiency Nucleoside analogues

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21世纪促进健康和预防疾病的新模式

英国医学杂志中文版 2008年第4期11卷 236-238页

作者： Robert N Butler Richard A Miller Daniel Perry Bruce A Cames T Franklin William Christine Cassel Jacob Brody marie A bernard Linda Partridge Thomas Kirkwood George M Martin S Jay Olshansky 周财亮(译) 张拓红(校) International Longevity Center New York USA University of Michigan Arm Arbor MI USA Alliance for Aging Resea Washington DCUSA University of Oklahoma Oklahoma City OKUSA University of Rochester School of Medicineand Denfistry NY USA American Board oflntemal Medicine Philadelphia PA USA University of Illinois at Chicago 1603 West Taylor Street Chicago IL 60612 USA Institute of Healthy Ageing University College London London Institute for Ageing and Health Newcastle University Newcastle American Federation for Aging Research Scatde WA USA 不详

随着年龄的增长，人类患病的可能性逐渐增加。因此，本文作者Robert Butler和他的同事认为干预人体衰老进程比治疗单个疾病更有效。

关键词：预防疾病健康衰老进程治疗单

Antigenicity of Synthetic Peptides Derived from Plasmodium Apoptosis-Linked Pathogenicity Factors

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Journal of Life Sciences 2012年第6期6卷 587-594页

作者： Ulrick Bisvigou Estelle Sonya Zang-Edou Florian Noulin Rafika Zatra Ludovic Mevono Jean-bernard Lekana-Douki Dominique Mazier Frederick Gay Fousseyni S. Toure Ndouo Unit of Medical Parasitology International Centre for Medical Research of Franceville (CIRMF) Franceville B.P. 769 Gabon Departement de Sante Publique de Medecine Legale et du Travail Universite des Sciences de la Sante Libreville B.P. 4009 Gabon Medical Research Unit Albert Sehweitzer Hospital Lambarene Gabon Departement de Parasitologie-Mycologie Medecine Tropicale Universitd des Sciences de la Sante Libreville B.P. 4009 Gabon Inserm/UPMC UMR S 945 Universite Pierre et Marie Curie Paris France AP-HP Groupe Hospitalier Pitid-Salpetriere Service Parasitologie-Mycologie Paris France

Background： Plasmodium falciparum malaria remains a major life-threatening disease. Recently, the Plasmodium apoptosis-linked pathogenicity factors （PALPF） have been identified. These antigens PALPF are expressed only by P falciparum-infected erythrocytes triggering endothelial cell apoptosis （apoptogenic）. Methods： We designed ten synthetic peptides （PI to P10） from PALPF： PF07 0032, PF10_0226, PFI0130c, PFD0875c and MAL13P1.206, and analyzed their antigenicity with an ELISA method using plasma samples from subjects living in Dienga, Gabon. Results： Four peptides showed good reactivity with human antibodies. The prevalence rate of specific IgG was 61%, 51%, 44% and 34% for P5, P6, P4 and P2, respectively. The median optical density of total IgG anti-P2 was higher than that directed against P4 and P6 （P = 0.009; P = 0.012 respectively）. The prevalence rate oflgG subclasses determined with plasma samples recognizing peptide 5 for IgGl, 2, 3 and 4 isotypes was 69%, 45%, 76% and 62%, respectively. All the subjects had at least one immunoglobulin subclass, while 13 （44%） had both IgG1 and IgG3 antibodies. There was no significant difference in the prevalence rate of anti-P5 IgG1, IgG3 and IgG4. Conclusion： These results warrant further immunogenicity studies of peptides 2, 4, 5 and 6 with a view of a tentative to antimalarial vaccine development.

关键词： Malaria vaccine candidate antigenicity immunoglobulin IgG PALPE

Religion and “Zero-Dose” Vaccination Status in Children Aged 12 to 23 Months in Benin and Togo: “Evidence of Demographic and Health Survey and Multiple Indicator Cluster Surveys”

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Open Journal of Epidemiology（流行病学期刊） 2023年第4期

作者： Nyulelen Toyi Mangbassim Alphonse Kpozehouen Jacques Zinsou Saizonou Nicolas Gaffan Aissata Ba sidibe marie Therese Guigui Yaovi Temfan Toke Dadja Essoya Landoh Assima-Essodom Kalao

Characterization of sFRP2-like in amphioxus:insights into the evolutionary conservation of Wnt antagonizing function

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Characterization of sFRP2-like in amphioxus:insights into th...

Prevalence of Ventilatory Function Abnormalities in Residents of Attecoube Lagune,Abidjan (Côte d’Ivoire)

2012全国发育生物学大会

作者： Weihua Kong~a,Yongjie Yang~a,Tianxiao Zhang~a,De-Li Shi~(a,b),Yanjun Zhang~a a.Institute of Developmental Biology,School of Life Sciences,Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology,Shandong University,Jinan,250100 b.Groupe de Biologie Exp’ erimentale,Laboratoire de Biologie du D’eveloppement,CNRS UMR 7622,Universit ’e Pierre et marie Curie,9 quai Saint-bernard,75005,Paris,France

Wnt signaling plays a key role in embryonic patterning and morphogenetic *** secreted Frizzled-related proteins(sFRPs) antagonize Wnt signaling,but their roles in development are poorly *** determine whether function of sFRPs is conserved between amphioxus and vertebrates,we characterized sFRP2-like function in the amphioxus,Branchiostoma belcheri tsingtauense(***).As in other species of Branchiostome,in B. belcheri,expression of sFRP2-like is restricted to the mesendoderm during gastrulation and to the anterior mesoderm and endoderm during *** analyses in frog(Xenopus laevis) indicate that amphioxus sFRP2-like potently inhibits a multitude of vertebrate Wnt proteins,both canonical and ***,sFRP-2 probably functions in amphioxus embryos to inhibit Wnt signaling ***,the activity of sFRP2-like on canonical Wnts is consistent with previous works showing that this pathway is involved in anteroposterior ***,dorsal overexpression of amphioxus sFRP2-like in Xenopus embryos,like inhibition of Wnt11,blocks gastrulation movements. This implies that sFRP2-like may also modulate Wnt signaling during gastrulation movements in amphioxus. Conclusions:Our functional analysis suggests an evolutionarily conserved function of sFRP in respect to their specificity and mode of operation on Wnt signaling.

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Health（健康） 2023年第8期

作者： Affou Séraphin Wognin Loukou Leandre Konan Esme marie Laure Essis Joseph Blaise Otshudi’a Ndjekaoma Ossey bernard Yapo Issaka Tiembre