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Va.ia.ion in Ca.echin Composition of Popula.ly Cultiva.ed Tea.Clones in Ea.t a.rica.(Kenya.

a.erica. Journa. of Pla.t Sciences 2013年第3期4卷 628-640页

作者： Leonida.Cherotich Sa.son M. Ka.unya.a.os a.a.onya.Solomon W. Msomba.marie a. uwimana John K. Wa.yoko Phillip O. Owuor Depa.tment of Chemistry Maseno University Maseno Kenya Institute of Biotechnology Resea.ch (IBR) Jomo Kenyatta University of Agriculture and Technology Nairobi Kenya Office Des Cultures Industrielles du Rwa.da.The’ (OCIR The’) Kigali Rwanda Tea.Resea.ch Founda.ion of Kenya Kericho Kenya Tea.Resea.ch Institute of Ta.za.ia Dar Es Salaam Tanzania

Tea.polyphenols a.d ca.echins ha.e ga.ned prominence in determina.ion of tea.qua.ity. Tea.lea.es conta.n la.ge a.ounts of ca.echins a.d their deriva.ives a.d these ha.e shown positive effects on huma. hea.th. a. experiment wa. ca.ried out to determine the level of ca.echins a.d polyphenols in 20 new clones found in two distinct tea.growing a.ea.. The tria. comprising twenty clones wa. esta.lished in two distinct sites in Kenya.using ra.domized complete block design with three replica.es a.d consisted of 10 popula. cultiva.s widely cultiva.ed in the La.e Victoria.Ba.in a.d a.ditiona. 10 newly improved clones. Tea.lea. sa.ples were collected a.ross two sea.ons;dry a.d wet sea.ons. Tea.qua.ity pa.a.eters enta.ling ca.echins, ca.feine a.d tota. polyphenols wa. genera.ed for the 20 clones a.ross the two sea.ons a.d sites. The ISO 14502-1 a.d ISO 14502-1:2005 procedures were used for polyphenol a.d ca.echin a.a.yses, respectively. The a.OVa.results genera.ed indica.ed tha. the level of ca.echins a.d polyphenols in tea.were significa.tly different (p 0.05) a.d va.ieta. dependent. Genera.ly, the a.sa. va.ieties ha. higher levels of ca.echins a.d polyphenols tha. the china.y a.d ca.bod va.ieties, indica.ing why they a.e popula.ly cultiva.ed in the Ea.t a.rica. region a.d whose tea.qua.ity is highly rega.ded. Furthermore, the results from principle component a.a.ysis (PCa. grouped the clones into three ma.or clusters with one comprising of high qua.ity a.sa. va.ieties, a.mixture of modera.e qua.ity a.sa., ca.bod a.d china.y va.ieties a.d low ca.echin content a.sa. a.thocya.in-rich va.iety. It is concluded tha. the level of ca.echins in tea.pla.ts a.e va.ieta. dependent, a.though environmenta. stress ha. effects on the synthesis of fla.a.oids. The results demonstra.ed tha. the differences in the a.cumula.ion of ca.echins a.ong the tea.clones could be importa.t for the discrimina.ion of clona. diversity.

关键词： Tea Hea.th Ca.ellia sinensis Ca.echins Va.ia.ion Kenya

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Non-coding RNa.:Role in dia.etic foot a.d wound hea.ing

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World Journa. of Dia.etes 2022年第12期13卷 1001-1013页

作者： Yi-Bo Ta.g Muhuza.marie Pa.fa.te uwimana Shu-Qi Zhu Li-Xia.Zha.g Qi Wu Zha.-Xia.Lia.g Depa.tment of Obstetrics Women’s Hospital School of MedicineZhejiang UniversityHangzhou 310006Zhejiang ProvinceChina

Dia.etic foot ulcer(DFU)a.d poor wound hea.ing a.e chronic complica.ions in pa.ients with *** increa.ing incidence of DFU ha. resulted in huge pressure *** a.d trea.ing this condition a.e therefore of grea. importa.ce to control morbidity a.d improve *** new ma.kers with potentia. dia.nostic a.d thera.eutic utility in DFU ha. ga.hered increa.ing *** hea.ing is a.process divided into three sta.es:Infla.ma.ion,prolifera.ion,a.d ***-coding RNa.(ncRNa.),which a.e sma.l protected molecules tra.scribed from the genome without protein tra.sla.ion function,ha.e emerged a. importa.t regula.ors of dia.etes *** deregula.ion of ncRNa. ma. be linked to a.celera.ed DFU development a.d dela.ed wound ***,ncRNa. ca. be used for thera.eutic purposes in dia.etic wound ***,we summa.ize the role of microRNa.,long ncRNa.,a.d circula. RNa. in diverse sta.es of DFU wound hea.ing a.d their potentia. use a. novel thera.eutic ta.gets.

关键词： Dia.etic foot ulcer Wound hea.ing MicroRNA Long non-coding RNa. Circula. RNa. Infla.ma.ion Prolifera.ion Regenera.ion

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Senda. Five Yea.s on: Reflections on the Role of Interna.iona. La. in the Crea.ion a.d Reduction of Disa.ter Risk

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Interna.iona. Journa. of Disa.ter Risk Science 2020年第2期11卷 230-238页

作者： marie a.onsson-Storrier School of La. University of ReadingReading RG66EP.UK

This a.ticle offers a.critica. exa.ina.ion of the position of the Senda. Fra.ework for Disa.ter Risk Reduction 2015–2030 within interna.iona. la.. It is a.gued tha. a.y interroga.ion into the rela.ionship between interna.iona. la. a.d disa.ter risk reduction(DRR) must begin not with existing DRR la.s a.d policies, but ra.her with a. enquiry into the na.ure of disa.ter risk a.d the role of interna.iona. la. in its crea.ion a.d reduction. It is demonstra.ed how, while a.ea. such a. interna.iona. huma. rights la. ca. be utilized to enforce obliga.ions in support of DRR, other a.ea.—in pa.ticula. interna.iona. investment la.—a.tively work to undermine DRR efforts. In order for interna.iona. la. to be a.productive tool in the reduction of disa.ter risk, interna.iona. la.yers must enga.e with critica. work in disa.ter studies a.d explore the role tha. interna.iona. la. ha. pla.ed, a.d ca. pla., in crea.ing a.d a.dressing ha.a.ds, vulnera.ilities, a.d ca.a.ities.

关键词： Disa.ter risk crea.ion Disa.ter risk reduction Interna.iona. la. Senda. Fra.ework

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The Globa. Sta.da.d Stra.otype-section a.d Point （GSSP） for the ba.e of the Eocene Series in the Da.a.iya.section （Egypt）

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Episodes 2007年第4期30卷 271-286页

作者： marie-Pierre a.bry Kha.ed Ouda.Christia. Dupuis Willia. a., Berggren John a. Va. Couvering 无 Depa.tment of Ea.th a.d Pla.eta.y Sciences Rutgers University 610 Taylor Road Piscataway New Jersey 08554 USA8 Depa.tment of Geology University of Assiut Assiut Egypt Géologie Fonda.enta.e et a.pliquée Mons PolytechnicsRue de Houdain 9 B-7000 Mons Belgium The Micropa.eontology Project 256 Fifth Avenue New York NY 10001 USA the Members of the Working Group on the Pa.eocene/Eocene Bounda.y

The GSSP for the ba.e of the Eocene Series is loca.ed a. 1.58 m a.ove the ba.e of Section DBH in the Da.a.iya.Qua.ry, on the ea.t ba.k of the Nile River, a.out 35 km south of Luxor, Egypt. It is the ba.e of Bed 1 of the Da.a.yia.Qua.ry Beds of the El Ma.miya.Member of the Esna.Forma.ion, interpreted a. ha.ing recorded the ba.a. inflection of the ca.bon isotope excursion （CIE）, a.prominent （3 to 5%） geochemica. signa.ure which is recorded in ma.ine （deep a.d sha.low） a.d terrestria. settings a.ound the world. The Pa.eocene/Eocene bounda.y is thus truly a.globa.ly correla.a.le chronostra.igra.hic level.

关键词：层型断面始新世第三纪下层埃及

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Determina.ion of Electron Collision Cross Sections Set for Tetra.ethysila.e

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Pla.ma.Science a.d Technology 2007年第6期9卷 756-759页

作者： marie-Cla.de BORDa.E Toulouse University La.La.E UMR 5213 CNRS-UPSPaul Sabatier University118Route de Narbonne31062 Toulouse CedexFrance

a.swa.m a.a.ysis technique ba.ed on the solution of the Boltzma.n equa.ion is used to derive low energy electron collision cross sections for tetra.ethylsila.e （TMS）. The ca.cula.ed swa.m pa.a.eters with this first a.a.la.le cross sections set is consistent with mea.ured va.ues of the swa.m pa.a.eters. Ca.cula.ions of tra.sport pa.a.eters in mixtures of TMS with a.gon a.e a.so presented.

关键词： tetra.ethysila.e electron cross section swa.m pa.a.eters

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Explora.ory Study of Intolera.ce of Uncerta.nty a.d Its Cognitive Processes by the Stroop Ta.k a.ong Pa.ents of a.Childhood Ca.cer Survivor

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Psycho-Oncologie 2023年第4期17卷 257-266页

作者： marie Va.der Ha.gen a.ne-marie Service de Psychologie de la.sa.té/Unitéde Resea.ch Unit for a.Life-Course Perspective on Hea.th a.d Educa.ion-(RUCHE ULiège)University of LiègeLiège4000Belgium

*** study ha. exa.ined the rela.ionship between the fa.tor of intolera.ce of uncerta.nty a.d its effects on the cognitive processes a.ong pa.ents of a.childhood ca.cer *** of uncerta.nty is a.centra. fa.tor in genera.ized a.xiety disorder;a. a.xiety disorder in which impa.red processing of cognitive informa.ion in the form of cognitive bia.es is a.so *** a.m of the study wa. to mea.ure,via.a.cla.sica. Stroop test a.d a. emotiona. Stroop test,the orienta.ion of selective a.tention in rela.ion to the uncerta.nty intolera.ce ***.61 pa.ents of a.childhood ca.cer survivor(a.ed 4 to 6 yea.s)were recruited from hospita.s in the Province of Liege(Belgium).Pa.ents completed questionna.res on intolera.ce of uncerta.nty a.d its a.socia.ed fa.tors(i.e.,usefulness of worry,cognitive a.oida.ce,problem-solving a.titude,a.d rumina.ions)a.d performed a.Stroop test a.d a. emotiona. Stroop *** correla.ions a.d multiple linea. regressions were *** results indica.ed positive a.d significa.t correla.ions between the emotiona. Stroop(nega.ive interference index)a.d intolera.ce to uncerta.nty but a.so with repetitive thoughts(rumina.ions)a.d *** regressions showed tha. depressive symptoms seem to contribute to expla.ning longer la.encies for the interference condition(color word written in a.other color).*** ha.e been published to improve the ma.a.ement of pa.ents of a.childhood ca.cer survivor,but pa.ent-centered neuropsychologica. studies a.e still needed a.d should be developed to improve prevention a.d detection initia.ives for these fa.ilies.

关键词： Pa.ents childhood ca.cer survivor Stroop intolera.ce of uncerta.nty

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Direct molecula.-level nea.-field pla.mon a.d tempera.ure a.sessment in a.single pla.monic hotspot

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Light(Science & a.plica.ions) 2020年第1期9卷 1673-1685页

作者： marie Richa.d-La.roix Volker Deckert Leibniz Institute of Photonic Technology(IPHT) Albert-Einstein-Strasse 9D-07745 JenaGermany Institute of Physica. Chemistry a.d a.be Center of Photonics University of JenaHelmholtzweg 4D-07743 JenaGermany

Tip-enha.ced Ra.a. spectroscopy(TERS)is currently widely recognized a. a. essentia. but still emergent technique for exploring the ***,our la.k of comprehension of crucia. pa.a.eters still limits its potentia. a. a.user-friendly a.a.ytica. *** tip’s surfa.e pla.mon resona.ce,hea.ing due to nea.-field tempera.ure rise,a.d spa.ia. resolution a.e undoubtedly three cha.lenging experimenta. pa.a.eters to ***,they a.e a.so the most funda.enta.ly releva.t pa.a.eters to explore,beca.se they ultima.ely influence the sta.e of the investiga.ed molecule a.d consequently the probed *** we propose a.stra.ghtforwa.d a.d purely experimenta. method to a.cess qua.tita.ive informa.ion of the pla.mon resona.ce a.d nea.-field tempera.ure experienced exclusively by the molecules directly contributing to the TERS *** deta.led nea.-field optica. response,both a. the molecula. level a.d a. a.function of time,is eva.ua.ed using sta.da.d TERS experimenta. equipment by simulta.eously probing the Stokes a.d a.ti-Stokes spectra. ***-a.sembled 16-merca.tohexa.odeca.oic a.id monola.ers cova.ently bond to a. ultra.fla. gold surfa.e were used a. a.*** of blinking lines in the spectra.a.so provides crucia. informa.ion on the la.era. resolution a.d indica.ion of a.omic-sca.e therma.ly induced morphologica. cha.ges of the tip during the *** study provides a.cess to unprecedented molecula.-level informa.ion on physica. pa.a.eters tha. crucia.ly a.fect experiments under TERS *** study thereby improves the usa.ility of TERS in da.-to-da. *** obta.ned informa.ion is of centra. importa.ce for a.y experimenta. pla.monic investiga.ion a.d for the a.plica.ion of TERS in the field of na.osca.e thermometry.

关键词： stra.ght purely thereby

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Va.ia.ion of Tra.sition Cha.a.teristics in a.Wa.l Jet

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Journa. of Therma. Science 2003年第2期12卷 167-170页

作者： marie-Fra.coise Scibilia Centre Na.iona. de la.Recherche Scientifique ParisFrance

The cha.a.teristics of a.la.ina. wa.l jet submitted to different configura.ions ha.e been experimenta.ly explored in order to obta.n a.better knowledge of tra.sition modifica.ions,In fa.t different pa.a.eters ca. a.celera.e or dela. the tra.sition using a.smooth or rough surfa.e,hea.ed or not,submitted to vibra.ions or not .In this study,significa.t effects ca. be *** ha. been possible to mea.ure the beginning of growth ra.es of disturba.ce a.plitude using a.wind tunnel a.d compa.ing the results with the linea. sta.ility theory.

关键词： wa.l jet tra.sition a.oustic vibra.ion hea. tra.sfer turbulence roughness.

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Density Results in Sobolev Spa.es Whose Elements Va.ish on a.Pa.t of the Bounda.y

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Chinese a.na.s of Ma.hema.ics,Series B 2011年第6期32卷 823-846页

作者： Jea.-marie Emma.uel BERNa.D La.ora.oire a.a.yse et Proba.itilités Université d'Evry val d'Essonne23 Boulevard de France91037 EVRYFrance

This pa.er is devoted to the study of the subspa.e of Wm＇＂ of functions tha. va.ish on a.pa.t γ0 of the bounda.y. The a.thor gives a.crucia. estima.e of the Poinca.e consta.t in ba.ls centered on the bounda.y of γ0. Then, the convolution-tra.sla.ion method, a.va.ia.t of the sta.da.d mollifier technique, ca. be used to prove the density of smooth functions tha. va.ish in a.neighborhood of γ0, in this subspa.e. The result is first proved for m = 1, then genera.ized to the ca.e where m 〉 1, in a.y dimension, in the fra.ework of Lipschitz-continuous doma.n. However, a. ma. be expected, it is needed to ma.e a.ditiona. a.sumptions on the bounda.y of γ0, na.ely tha. it is loca.ly the gra.h of some Lipschitz-continuous function.

关键词： Density results Bounda.y va.ue problems Sobolev spa.es

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Rea.tiva.ion of la.ent tuberculosis with TNF inhibitors: critica. role of the beta.2 cha.n of the IL-12 receptor

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Cellula. & Molecula. Immunology 2021年第7期18卷 1644-1651页

作者： marie Robert Pierre Miossec Depa.tment of Clinica. Immunology a.d Rheuma.ology and immunogenomics and inflammation research unitUniversity of LyonHôpital Edouard HerriotLyonFrance

Tumor necrosis fa.tor(TNF)inhibitors ha.e improved a.lot the trea.ment of numerous disea.es,with the well-known exa.ple of rheuma.oid a.thritis(Ra..In the ea.ly 2000s,postma.keting da.a.quickly revea.ed a. a.a.ming number of severe tuberculosis(TB)under such *** findings were consistent with previous results in mice where TNF is essentia. for lymph node forma.ion a.d gra.uloma.*** effects of TNF inhibition on Ra.synovium structure a.e very simila. to those on gra.uloma.with cha.ges in cellula. intera.tions,cytokine,a.d chemokine *** a.dition to the role of TNF in gra.uloma.the interleukin(IL)-12/interferon(IFN)-γpa.hwa. is required for a. efficient host defense a.a.nst *** a.d seconda.y immunodeficiencies a.fecting this pa.hwa. lea. to severe ba.illus Ca.mette-Guérin(BCG)rea.tion or full *** chronic infla.ma.ion a. in Ra.induces a.systemic Th1 defect tha. predisposes to TB through specific downregula.ion of the IL-12Rß2 *** TNF inhibitors a.e initia.ed,this tra.siently increa.es this risk of TB,through effects on cellula. intera.tions in a.la.ent TB *** a.la.er sta.e,when a.better control disea.e a.tivity is obta.ned,the risk of TB is reduced but not *** the clea. benefit from TNF inhibition,la.ent TB infection screening a. ba.eline is essentia. for a. optima. sa.ety.

关键词： tuberculosis TNF inhibition rheuma.oid a.thritis cytokines

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