检索结果-南通市图书馆

Particulate matter characterization in a steelworks using conventional sampling and innovative lidar observations

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Particuology 2016年第5期14卷 43-51页

作者： Benjamin Guinot Beatriz gonzalez Julia Perim De Faria Sumita Keclia Laboratoire d'Aerologie Universite de Toulouse CNRS Universite Paul-Sabatier 14 Avenue Edouard-Belin 31400 Toulouse France

Particulate matter （PM） emissions from steelworks cause public concern. Although end-of-pipe and pro- cess integrated measures have led to a significant drop in emissions of large particles from stacks, fine aerosols were not specifically considered, nor were emissions from fugitive and open sources. In this study, we deployed aerosol samplers together with a scanning ultra-violet （UV） lidar to characterize total suspended particles （TSP）, PM10, and PM2.5, in emissions from a large integrated steelworks in Spain over a 16-day period. We determined the content of carbonaceous, soluble inorganic, mineral dust, and metal species. A positive matrix factorization was carried out on our dataset. Despite mineral dust being predominant in all size fractions, the steelworks was clearly a source of carbonaceous species, resulting in production of secondary inorganic aerosols. In particular, stack emissions were a major contributor of fine particles, while open sources dominated the emissions of TSP, yielding up to 80% of particles larger than PM10. UV lidar provided 2D maps of aerosols in real time, with an ability to detect PM emissions and to visualize complex plumes. We suggest that air quality management of steelworks needs to focus on controlling large and coarse oarticle emissions, esoeciallv those from onen sources.

关键词： Fine aerosols Fugitive emissions Open sources Chemical composition Trace metals UV lidar

A Novel and Functional Artificial Bruch’s Membrane Made of Poly (ε-Caprolactone)/Gelatin for Retinal Pigment Epithelium Restoration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Bioscience and Biotechnology 2024年第8期15卷 443-461页

作者： López Edith Silva-Bermudez Phaedra gonzalez-Salinas Roberto Velasquillo Cristina Torres-Romero Abigail López-Colomé Ana María Pérez Armando Gina Prado-Prone Edgar Ramos-Martínez Iván Ramos-Martínez Quiroz-Mercado Hugo Hernández-Zimbrón Luis Fernando Instituto de Fisiologa Celular Universidad Nacional Autnoma de Mxico Ciudad de Mxico City Mxico Unidad de Ingeniería de Tejidos Terapia Celular y Medicina Regenerativa Instituto Nacional de Rehabilitación Luis Guiller-mo Ibarra Ibarra Ciudad de México México Departamento de Investigacin Asociacin Para Evitar la Ceguera Ciudad de Mxico Mxico Subdireccin de Investigacin Tecnolgica Instituto Nacional de Rehabilitacin Luis Guillermo Ibarra Ibarra Ciudad de Mxico Mxico Departamento de Biologa Celular y Tisular Facultad de Medicina Universidad Nacional Autnoma de Mxico Ciudad de Mxico Mxico Escuela de Ciencias Universidad Autnoma Benito Jurez de Oaxaca Oaxaca Mxico Departamento de Medicina y Zootecnia de Cerdos Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional utnoma de Mxico Mxico Laboratorio de Investigacion Interdisciplinaria rea de Optometria Escuela Nacional de Estudios Superiores Unidad Len Universidad Nacional Autnoma de Mxico Len Guanajuato Mxico Laboratorio Nacional de ptica de la Visin-Centro de Investigaciones en ptica Len Guanajuato Mxico

Purpose: The primary aim of this paper is to design, create, and improve functional and artificial Bruch’s membranes (BM) using bioengineering techniques, which can be applied in the treatment of maculopathies by supporting the growth and maintenance of retinal pigment epithelium (RPE) cells, thereby potentially enabling subretinal implantation in patients. Methods: We fabricated by electrospinning ultrathin 3D nanofibrous membranes from Polycaprolactone (PCL), and different concentrations of gelatin (5%, 15% and 30%). ARPE-19 cells were seeded onto these artificial membranes. MTT assays were performed in order to evaluate ARPE-19 cell viability and cytotoxicity. IF assays were realized to observe the ARPE-19 cells onto each membrane. Ultrastructure of the modified Bruch’s membrane and ARPE-19 morphology after 25 days of culture were studied with transmission and scanning electron microscopy. To evaluate expression changes in markers of ARPE-19 (RPE65 and ZO-1) qRT-PCR assays were realized. Data from three independent experiments were pooled and expressed as the mean SD. A confidence level of P 0.05 was considered to be statistically significant. Results ARPE-19 cells grew on PCL/Gelatin membranes mainly in PCL/30% gelatin combination, which had not cytotoxic effect. RPE65/cytokeratin-18/ and actin-positive ARPE-19 cells formed a correctly orientated monolayer of polygonal cells with morphological polarity. The apical cell surfaces exhibited abundant protruding microfolds. Moreover, zones of polygonal border look as if ARPE-19 cells fused among, suggesting the presence of tight junctions. The expression of RPE65 and ZO-1 was unchanged. Conclusions: PCL/30% Gelatine membranes may imitate the natural BM to such extent that they support RPE-cells and exhibited RPE-like morphology. The engineering of a human RPE monolayer with these artificial BM, emulating the in vivo retina, arouse their potential subretinal implantation in patients with wet age-related macular degene

关键词： Artificial Bruch’s Membrane Electrospinning ARPE-19 Cells Age-Related Macular Degeneration

Glial plasticity after hexahydrobenzene exposure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2016年第3期11卷 404-405页

作者： Tania Campos-Ordonez Oscar gonzalez-Perez Laboratory of Neurobiology School of PsychologyUniversity of Colima Medical Sciences PhD Program School of MedicineUniversity of Colima

The organic solvents are not only utilized in industrial processes,but also as drugs of *** fact,solvent consumption represents the fourth option for drug users just after alcohol,tobacco and *** humans,intentional in... 详细信息

关键词： intentional tobacco plasticity utilized volatile alcohol exposure abuse morphological microglia

Oxidative effects of the harmful algal blooms on primary organisms of the food web

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

BIOCELL 2019年第2期43卷 41-50页

作者： JOAQUIN CABRERA PAULA MARIELA gonzalez SUSANA PUNTARULO Universidad de Buenos Aires Facultad de Farmacia y BioquimicaFisicoquimica.Buenos AiresArgentina CONIONI CETET-Universidad de Buenos Aires.Instituto de Bioquimica y Medicina Molecular(IBI IBI MOLOL).Buenos Aires Argentina

Degraded water quality from nutrient pollution,physical,biological,and other chemical factors contributes to the development and persistence of many harmful algal blooms(HAB s).The complex dynamics of the HAB s is a challenge to marine ecosystems for the toxic effects *** consequences include fish,bird,and mammal mortality,respiratory or digestive tract problems,memory loss,seizures,lesions and skin irritation in many *** review is intended to briefly summarize the recent reported information on harmful marine toxin deleterious effects over the primary organisms of the food web,namely algae,zooplankton and *** focus is made on oxidative stress status of cells and *** though in situ field research is less controlled than laboratory studies,in which the organisms are directly exposed to the toxins under consideration,both types of approaches are required to fully understand such a complex *** top of that,the contribution of the increasing water temperatures in the sea,as a consequence of the global climate change,will be addressed as a topic for further studies,to evaluate the effect on regulating algal growth,species composition,trophic structure,metabolic stress and function of aquatic ecosystems.

关键词： Harmful algal toxins oxidative stress algae zooplankton invertebrates

Parking Availability Prediction with Coarse-Grained Human Mobility Data

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第6期71卷 4355-4375页

作者： Aurora gonzalez-Vidal Fernando Terroso-Sáenz Antonio Skarmeta University of Murcia Murcia30003Spain Universidad Católica de Murcia(UCAM) Murcia30107Spain

Nowadays,the anticipation of parking-space demand is an instrumental service in order to reduce traffic congestion levels in urban *** purpose of our work is to study,design and develop a parking-availability predictor that extracts the knowledge from human mobility data,based on the anonymized human displacements of an urban area,and also from weather *** of the existing solutions for this prediction take as contextual data the current road-traffic state defined at very high temporal or spatial ***,access to this type of fine-grained location data is usually quite limited due to several economic or privacy-related *** overcome this limitation,our proposal uses urban areas that are defined at very low spatial and temporal *** conducted several experiments using three Artificial Neural Networks:Multilayer Perceptron,Gated Recurrent Units and bidirectional Long Short Term Memory networks and we tested their suitability using different combinations of *** metrics are provided for the sake of comparison within our study and between other *** solution has been evaluated in a real-world testbed in the city of Murcia(Spain)integrating an open human-mobility dataset showing high accuracy.A MAPE between 4%and 10%was reported in horizons of 1 to 3 h.

关键词： Parking space human mobility mining recurrent neural networks prediction

Spectrum of anemia associated with chronic liver disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第37期15卷 4653-4658页

作者： Rosario gonzalez-Casas E Anthony Jones Ricardo Moreno-Otero Digestive Disease Service and Center for Investigation of Hepatic and Digestive Diseases University Hospital La Princesa Autonomous University of Madrid Madrid 28006 Spain

Anemia of diverse etiology is a common complication of chronic liver diseases. The causes of anemia include acute or chronic gastrointestinal hemorrhage, and hypersplenism secondary to portal hypertension. Severe hepatocellular disease predisposes to hemorrhage because of impaired blood coagulation caused by deficiency of blood coagulation factors synthesized by hepatocytes, and/or thrombocytopenia. Aplastic anemia, which is characterized by pancytopenia and hypocellular bone marrow, may follow the development of hepatitis. Its presentation includes progressive anemia and hemorrhagic manifestations. Hematological complications of combination therapy for chronic viral hepatitis include clinically signif icant anemia, secondary to treatment with ribavirin and/or interferon. Ribavirininduced hemolysis can be reversed by reducing the dose of the drug or discontinuing it altogether. Interferons may contribute to anemia by inducing bone marrow suppression. Alcohol ingestion is implicated in the pathogenesis of chronic liver disease and may contribute to associated anemia. In patients with chronic liver disease, anemia may be exacerbated by defi ciency of folic acid and/or vitamin B12 that can occur secondary to inadequate dietary intake or malabsorption.

关键词： Anemia Liver disease Liver failure Aplastic anemia Pegylated interferon Ribavirin Alcohol

Two-tiered reconstruction of Late Pleistocene to Holocene changes in the freezing level height in the largest glacierized areas of the Colombian Andes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mountain Science 2022年第3期19卷 615-636页

作者： Daniel RUIZ-CARRASCAL Daniel gonzalez-DUQUE Isabel RESTREPO-CORREA Department of Ecology Evolution and Environmental BiologyColumbia University in the City of New YorkNew YorkNY 10027USA Department of Civil and Environmental Engineering Vanderbilt University40024th Avenue South269 Jacobs HallNashville TN 3720USA Department of Earth Sciences Universidad EAFITCarrera 49 No.7Sur-50MedellínColombia

One way of deducing vertical shifts in the altitudinal distribution of Colombian high-altitude páramo environments is by inferring fluctuations in the height of the local freezing *** our research,we are implementing two complementary approaches to reconstruct Late Pleistocene to Holocene changes in the freezing level height(FLH)in two of the most extensively glacier-covered areas of the northern *** combined remote sensing and field-based geomorphological mapping with time-series reconstruction of changes in the altitude of the 0°C *** in the FLH were based on alreadypublished~30 kyr paleo-reconstructions of sea surface temperatures(SSTs)of the eastern tropical Pacific and the western tropical Atlantic,as well as on reconstructed long-term sea level changes and empirical orthogonal functions of present-day(historical)Indo-Pacific and tropical Atlantic SST *** also analyzed the probability distribution of air-sea temperature differences and the spatial distribution of grid points with SSTs above the minimum threshold necessary to initiate deep *** considered available historical nearsurface and free air temperature data of ERA-Interim reanalysis products,General Circulation Model(GCM)simulations,weather stations,and(deployed by our group)digital sensors,to assess the normal Environmental Lapse Rates(ELRs)at the regional to local *** combined maps of glacial landforms and our reconstructed FLHs provided us with a wellfounded inference of potential past glacier advances,narrowing down the coarse resolution of ice margins suggested by previous research *** extent of the areas with temperatures below the freezing point suggested here for the summits of our main study site exceeds in magnitude the corresponding glacier icecaps and front advances proposed by previous ***,our average lowest altitudes of the FLH for our comparative site are consistently above the main glacier-front advances previously su

关键词： Glacial events Colombian Andes Climate reconstruction Geomorphology Mountain glaciers Freezing level height

Hybrid magnetorheological elastomers enable versatile soft actuators

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

npj Computational Materials 2022年第1期8卷 1546-1559页

作者： Miguel Angel Moreno-Mateos Mokarram Hossain Paul Steinmann Daniel Garcia-gonzalez Department of Continuum Mechanics and Structural Analysis Universidad Carlos III de MadridAvda.de la Universidad 3028911LeganésMadridSpain Zienkiewicz Centre for Computational Engineering Faculty of Science and EngineeringSwansea UniversitySA18ENSwanseaUK Institute of Applied Mechanics University of Erlangen-NurembergEgerland Str.5ErlangenGermany Glasgow Computational Engineering Centre School of EngineeringUniversity of GlasgowG128QQGlasgowUK

Recent advances in magnetorheological elastomers(MREs)have posed the question on whether the combination of both soft-and hard-magnetic particles may open new routes to design versatile multifunctional ***,we conceptualise ultra-soft hybrid MREs(≈1–10 kPa stiffness)combining experimental and computational ***,a comprehensive experimental characterisation is *** results unravel that the magneto-mechanical performance of hybrid MREs can be optimised by selecting an adequate mixing ratio between ***,a multi-physics computational framework provides insights into the synergistic magneto-mechanical interactions at the *** particles amplify the magnetisation and hard particles contribute to torsional *** numerical results suggest that the effective response of hybrid MREs emerges from these intricate ***,we uncover exciting possibilities to push the frontiers of MRE *** are demonstrated by simulating a bimorph beam that provides actuation flexibility either enhancing mechanical bending or material stiffening,depending on the magnetic stimulation.

关键词： versatile magneto enable

Current protective strategies in liver surgery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第48期16卷 6098-6103页

作者： Kurinchi S Gurusamy Hector D gonzalez Brian R Davidson HPB and Liver Transplantation Royal Free CampusUniversity College London Medical SchoolRoyal Free Hospital

During liver resection surgery for cancer or liver transplantation,the liver is subject to ischaemia (reduction in blood flow) followed by reperfusion (restoration of blood flow),which results in liver injury [ischemiareperfusion (IR) or IR injury]. Modulation of IR injury can be achieved in various ways. These include hypothermia,ischaemic preconditioning (IPC) (brief cycles of ischaemia followed by reperfusion of the organ before the prolonged period of ischaemia i.e. a conditioning response),ischaemic postconditioning (conditioning after the prolonged period of ischaemia but before the reperfusion),pharmacological agents to decrease IR injury,genetic modulation of IR injury,and machine perfusion (pulsatile perfusion). Hypothermia decreases the metabolic functions and the oxygen consumption of organs. Static cold storage in University of Wisconsin solution reduces IR injury and has prolonged organ storage and improved the function of transplanted grafts. There is currently no evidence for any clinical advantage in the use of alternate solutions for static cold storage. Although experimental data from animal models suggest that IPC,ischaemic postconditioning,various pharma-cological agents,gene therapy,and machine perfusion decrease IR injury,none of these interventions can be recommended in clinical practice. This is because of the lack of randomized controlled trials assessing the safety and efficacy of ischaemic postconditioning,gene therapy,and machine perfusion. Randomized controlled trials and systematic reviews of randomized controlled trials assessing the safety and efficacy of IPC and various pharmacological agents have demonstrated biochemical or histological improvements but this has not translated to clinical benefit. Further well designed randomized controlled trials are necessary to assess the various new protective strategies in liver resection.

关键词： Liver Hepatectomy Liver transplantation Ischemia-reperfusion injury Hypothermia Ischaemic preconditioning