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Laparoscopic surgery for colorectal liver metastases:moving forward while keeping feet on the ground

Hepatobiliary Surgery and Nutrition 2021年第1期10卷 107-109页

作者： mariano cesare giglio Roberto Ivan Troisi Division of HPB Minimally Invasive and Robotic SurgeryDepartment of Clinical Medicine and SurgeryFederico II University HospitalNaplesItaly

The laparoscopic approach to the surgical treatment of colorectal liver metastases(CRLMs)is supported nowadays by high evidence(1).In the hand of expert surgeons,patients undergoing laparoscopic liver surgery(LLS)for CLRMs benefit from a number of advantages,including a shorter postoperative in-hospital stay,less pain,fewer complications and a faster recovery(1).More importantly,all these profits are achieved while preserving the oncological outcomes,which are not-inferior to those achieved by open procedures(1).Recently published long-term results of randomized trials have shown similar patient survival after laparoscopic and open surgery for CRLM(2).

关键词： surgery colorectal faster

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Big size is not all, even better!

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Hepatobiliary Surgery and Nutrition 2019年第5期8卷 539-540页

作者： Roberto Ivan Troisi mariano cesare giglio Roberto Montalti Department of Clinical Medicine and Surgery Federico II University of NaplesNaplesItaly Department of Liver and Small Bowel Transplantation Hepato-Biliary and Pancreatic SurgeryKing Faisal Specialist Hospital and Research CenterRiyadhKingdom of Saudi Arabia Department of Public Health Federico II University of NaplesNaplesItaly

We read with interest the article entitled"Comprehensive Complication Index validates improved outcomes over time despiteincreased complexity in 3707 consecutive hepatectomies"by Cloydet al.(1).This article focused on... 详细信息

关键词： entitled consecutive despite

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Neutrophil-to-lymphocyte ratio as a prognostic factor for survival in patients with colorectal liver metastases: A systematic review

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World Journal of Clinical Oncology 2022年第10期13卷 822-834页

作者： Menelaos Papakonstantinou Stylianos Fiflis Gregory Christodoulidis mariano cesare giglio Eleni Louri Savvas Mavromatidis Dimitrios Giakoustidis Vasileios N Papadopoulos Alexandros Giakoustidis Department of Surgery General Hospital PapageorgiouAristotle University of ThessalonikiThessaloniki 56429Greece Department of General Surgery University Hospital of LarissaLarissa 41110Greece Department of Clinical Medicine and Surgery Federico II University of NaplesNaples 80138Italy

BACKGROUND The inflammatory response to tumor has been proven to be closely related to the prognosis of colorectal *** to lymphocyte ratio(NLR)is a widely available inflammatory biomarker that may have prognostic value for patients with colorectal liver metastasis(CRLM).AIM To assess the role of NLR as a prognostic factor of survival and tumor recurrence in patients with *** A systematic literature search of PubMed,Cochrane Library and *** was conducted by two independent researchers in order to minimize potential errors and *** were discussed and settled between three *** including patients undergoing different types of medical interventions for the treatment of CRLM and evaluating the correlation between pretreatment NLR and disease-free survival(DFS)and overall survival(OS)were included in the *** studies,involving 3283 patients matched our inclusion *** In the studies included,NLR was measured before the intervention and the NLR thresholds ranged between 1.9 and *** studies used 5 as the cut-off *** metastases were treated with hepatectomy with or without chemotherapy regimens in 13 studies and with radiofrequency ablation,radioembolization,chemoembolization or solely with chemotherapy in 6 *** NLR was associated with decreased OS and DFS after liver resection or other medical ***,high NLR was associated with poor *** the contrary,CRLM patients with low pretreatment NLR demonstrated improved OS and *** could potentially be used as a predictive factor of survival and tumor recurrence in patients with CRLM treated with interventions of any modality,including surgery,chemotherapy and ablative *** NLR is an inflammatory biomarker that demonstrates considerable prognostic *** pretreatment NLR is associated with poor OS and DFS in patients with CRLM who are submitted to different treatments.

关键词： Neutrophil-to-lymphocyte ratio Colorectal liver metastasis Prognosis Survival

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New frontiers in liver ultrasound:From mono to multi parametricity

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World Journal of Gastrointestinal Oncology 2021年第10期13卷 1302-1316页

作者： Tommaso Vincenzo Bartolotta Adele Taibbi Angelo Randazzo cesare Gagliardo Department of Radiology University Hospital"Paolo Giaccone"Palermo 90127Italy Radiology Department Fondazione Istituto G.Giglio HospitalCefalù90015Italy Department of Biopathology and Medical and Forensic Biotechnologies University of PalermoPalermo 90127Italy

Modern liver ultrasonography(US)has become a“one-stop shop”able to provide not only anatomic and morphologic but also functional information about vascularity,stiffness and other various liver tissue *** US techniques allow a quantitative assessment of various liver *** scanning is no more limited to the visualized plane,but three-dimensional,volumetric acquisition and consequent post-processing are also ***,US scan can be consistently merged and visualized in real time with Computed Tomography and Magnetic Resonance Imaging *** and safe microbubble�based contrast agents allow a real time,dynamic study of contrast kinetic for the detection and characterization of focal liver *** can be used to guide loco-regional treatment of liver malignancies and to assess tumoral response either to interventional procedures or medical *** may also carry and deliver drugs under ultrasound *** plays a crucial role in diagnosing,treating and monitoring focal and diffuse liver *** the basis of personal experience and literature data,this paper is aimed to review the main topics involving recent advances in the field of liver ultrasound.

关键词： Ultrasonography Contrast-enhanced ultrasound Elastography Interventional Doppler ultrasonography

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