检索结果-南通市图书馆

神经损伤与功能重建 2024年第5期19卷 F0003-F0003页

作者： Monica Guerrero-Carrasco Imogen Targett Adrian Olmos-Alonso mariana vargas-caballero Diego Gomez-Nicola 杜一星(译) School of Biological Sciences University of SouthamptonSouthampton General HospitalSouthamptonUK Institute for Life Sciences(IfLS) University of SouthamptonSouthamptonUK 不详

数项在体研究表明,脂多糖模拟的全身炎症会引发中枢神经系统中由小胶质细胞驱动的炎症反应,其特征是炎症细胞因子和相关疾病行为的增加。然而,大多数研究诱发相对较高的全身炎症,并没有直接与人类在生命过程中经历的更常见的低度炎症事... 详细信息

数项在体研究表明,脂多糖模拟的全身炎症会引发中枢神经系统中由小胶质细胞驱动的炎症反应,其特征是炎症细胞因子和相关疾病行为的增加。然而,大多数研究诱发相对较高的全身炎症,并没有直接与人类在生命过程中经历的更常见的低度炎症事件进行比较。本研究利用小鼠研究低度全身炎症在生命早期对健康的影响,以及该事件如何影响阿尔茨海默病(AD)样病理的发生和严重程度。本研究结果表明,低度全身炎症会诱导阈下脑炎症,并促进CSF1R通路驱动的小胶质细胞增殖,这与高度全身炎症引起的影响相反。此外,低度脂多糖引起的反复全身性挑战会诱导疾病相关的小胶质细胞。最后,使用AD样病理诱导模型(102系小鼠),我们观察到在APP诱导之前重复剂量的低度全身性炎症预处理会在以后的生活中产生有害影响,导致Aβ沉积以及和疾病相关的小胶质细胞增加。本研究结果提示,阵发性低度全身炎症有可能影响与年龄相关的神经系统疾病(例如AD)的发作和严重程度。

关键词：阿尔茨海默病脂多糖疾病相关的小胶质细胞小胶质细胞增殖

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessment of the Sensitivity of Soil Parameters in Sediment Production in the Ichu River Experimental Basin

引用

Journal of Environmental Science and Engineering(A) 2023年第1期12卷 1-13页

作者： Ivan A.Ayala Bizarro Yunior AHuaman Paitan Marco Lopez Barrantes Jorge Ortega vargas Omar caballero sanchez Abdon Olivera Quintanilla Cesar Jurado Mancha Jessica Zuniga Mendoza Cesar Lifonzo Salcedo Faculty of Civil Engineering National University of HuancavelicaHuancavelica 09001Peru Faculty of Civil Engineering National University of San Cristobal of HuamangaAyacucho 05000Peru

This research aims to determine how much is the sensitivity of soil parameters in the production of sediments through the model distributed at the level of cells in the Ichu River Basin,which is located in the Andes of Peru,with an approximate surface area of 1,380.17 km2,corresponding to the control section and tributary to the Mantaro ***,for the evaluation of sensitivity determine the amount of sediments of the textures:silt,clay and *** achieve the objectives that have been raised in this research has been used the conceptual distributed hydrological model TETIS v9.1,which has been calibrated and validated using the climatic variables that are recorded at the hourly level in six weather stations and a hydrometric station,synthetic precipitation was also used withsatellite stations(CHIRPS)of the Climate Hazards Group that has registered with a grid of 0.05 degrees of resolution,from 1981 to the *** determine the solid component,the TETIS v9.1 model uses the equations developed in the CASCade 2 Dimensional SEDimentation model(CASC2D-SED)that presents conceptual approaches with physical *** sediment processes on slopes this CASC2D-SED model simulates in two dimensions,as well as helps to determine the quantification of sediments at any point in the basin considering all physical *** the other hand,the OpenLandMap data portal has been used for land cover data of the K factor corresponding to the susceptibility of the soil that can suffer losses due to ***,the Moderate Resolution Imaging Spectroradiometer(MODIS)observation system to determine the Normalized Difference Vegetation Indices(NDVI)for the culture factor *** parameter P corresponding to the conservation technique applied,has been developed using remote sensing techniques using the Google Earth Engine(GEE)***,the results obtained from the evaluation of the sensitivity of the parameters are significant,in this way the hypothesis that is raised is approv

关键词： Sediments distributed model CASC2D-SED model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Vapor Phase Decarbonylation of Furfural to Furan over Nickel Supported on SBA-15 Silica Catalysts

引用

Modern Research in Catalysis 2016年第3期5卷 85-94页

作者： Diana vargas-Hernández Juan Miguel Rubio-caballero Ramon Moreno-Tost Josefa María Mérida-Robles José Santamaría-González Antonio Jiménez-López María Ana Pérez-Cruz Rosario Hernández-Huesca Pedro Maireles-Torres Catedrática CONACYT—Universidad de Sonora Hermosillo México Departamento de Química Inorgánica Cristalografía y Minerología (Unidad Asociada al ICP-CSIC) Facultad de Ciencias Universidad de Málaga Málaga Spain Facultad de Ciencias Químicas Benemérita Universidad Autónoma de Puebla Puebla México

Vapor-phase transformations of furfural over SBA-15 silica supported Ni catalysts under H2 in a continuous-flow reactor at atmospheric pressure and 170°C and 230°C were investigated. Two different samples having Ni loadings of 5 and 20 wt% (denoted here by SBA-5Ni and SBA-20Ni, respectively) were prepared by impregnation and characterized by atomic absorption spectroscopy, N2 sorption analysis, X-ray diffraction, X-ray photoelectron spectroscopy, and transmission electron microscopy. Furan and furfuryl alcohol were two primary products resulting, respectively, from decarbonylation and hydrogenation of furfural. Under the conditions of the study, both reactions exhibited structure sensitivity evidenced by changes in product selectivities with variable Ni loadings. Compared with SBA-20Ni, the 5 wt% Ni catalyst showed better catalytic activity, reaching a furfural conversion of 100 mol% and a selectivity to furan of 98 mol%, after 5 h of time-on-stream at 230°C.

关键词： Ni-SBA-15 Furfural Hydrogenation Furan Furfuryl Alcohol

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：