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sleep Quality in Non Dialysis Chronic Kidney Disease: Associated Factors and Influence on Prognosis

International Journal of Clinical Medicine 2016年第7期7卷 481-486页

作者： jesús Calviño Lourdes Gonzalez-Tabarés secundino Cigarrán Beatriz Millán Monica Guijarro Carmen Cobelo maria-jesús sobrido Department of Nephrology Hospital Lucus Augusti EOXI Lugo-Cervo-Monforte Lugo Spain Department of Nephrology Hospital da Costa EOXI Lugo-Cervo-Monforte Burela Lugo Spain Department of Neurology Hospital Lucus Augusti EOXI Lugo-Cervo-Monforte Lugo Spain Department of Neurology Fundación Pública Galega de Medicina Xenómica-SERGAS Instituto de Investigación Sanitaria Santiago de Compostela Spain Department of Neurology Hospital San Rafael A Coru&ntildea Spain

Deficient sleep quality (sQ) has been linked with a higher hospitalization rate and mortality in dialysis patients, however the prevalence of sleep disorders and their influence on prognosis in non-dialysis chronic kidney disease (CKD) has been poorly investigated. The aim of this study was to assess factors related with sQ in CKD patients (stages I-IV) followed in a nephrology outpatient clinic as well as the long-term impact of sQ on patient’s outcome. Between January and May 2008, Pittsburgh sleep Quality Index (PsQI) was self-administered by 122 patients (68 males and 54 females) with a mean age of 65 years. Patients were classified as “good” (global PsQI sleepers (global PsQI ≥ 6). We identified 66 (54%) poor sleepers (Ps), characterized by an older age (66 ± 14.2 vs 57 ± 17.0, p s 26%, p se renal function (49 ± 19.1 vs 57 ± 23.2 ml/min, p s a significant correlation between phosphate and PsQI score (r = 0.234, p = 0.01), however no correlation with calcium or PTH. Vitamin D was also lower in Ps (17 ± 7.2 vs 23 ± 15.1 ng/ml, p spitalization rate was higher among Ps (64% vs 44%, p s period, there was also a trend towards higher mortality for Ps (18% vs 16%). In summary, over 50% of CKD patients have poor sQ, which was associated with older age, female gender, worse renal function, lower vitamin D and higher phosphate levels. Deficient sleep was associated with a greater probability of hospitalization and might be a prognostic marker in CKD.

关键词： Chronic Kidney Disease sleep Quality Hospitalization Pittsburgh sleep Quality Index Vitamin D

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Performance and potential of porous carbons derived of electrospun metal-organic frameworks for supercapacitor applications

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Journal of Energy Chemistry 2022年第10期31卷 348-353,I0008页

作者： Petra Agota szilagyi Ana Jorge sobrido school of Engineering and Materials science Queen Mary University of LondonLondon E14NSUK

supercapacitors(sCs) are energy storage devices with the ability to charge and discharge at very high rates. The fast accumulation and release of charges occurs either electrostatically or electrochemically. There are two types of capacitors: electric double layer capacitors(EDLCs) and pseudocapacitors. EDLCs are the most commercially available.

关键词： Electrospinning MOFs Porous carbons supercapacitors Electrodes Energy storage

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Morpholino studies shed light on the signaling pathways regulating axon regeneration in lampreys

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Neural Regeneration Research 2022年第7期17卷 1475-1477页

作者： Daniel sobrido-Cameán Antón Barreiro-Iglesias Department of Functional Biology Faculty of BiologyCIBUSUniversidade de Santiago de CompostelaSantiago de CompostelaA CoruñaSpain Department of Zoology University of CambridgeCambridgeUK

Lampreys are one of the most ancient extant vertebrates and they have become an animal model of interest for the study of spontaneous axon regeneration after a traumatic central nervous system *** to most mammals,lamp... 详细信息

关键词： traumatic regeneration injury

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serotonin controls axon and neuronal regeneration in the nervous system:lessons from regenerating animal models

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Neural Regeneration Research 2018年第2期13卷 237-238页

作者： daniel sobrido-cameán maría celina rodicio antón barreiro-iglesias department of functional biology cibusfaculty of biologyuniversidade de santiago de compostelaa CorunaSpain

Traumatic brain injury （TBI） is a mechanical injury to brain tissue that leads to an impairment of function and a broad spectrum of symptoms and disabilities; often, it is followed by diffuse axonal injury, which causes denaturation of the white matter and axon retraction, leaving patients with severe brain damage or even in a persistent vegetative state.

关键词： AMP HT lessons from regenerating animal models serotonin controls axon and neuronal regeneration in the nervous system TBI

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Electrospinning as a route to advanced carbon fibre materials for selected low-temperature electrochemical devices:A review

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Journal of Energy Chemistry 2021年第8期30卷 492-529,I0011页

作者： Yue Wen Matt D.R.Kok Jorge Pavel Victoria Tafoya Ana BJorge sobrido Ellsworth Bell Jeff T.Gostick servann Herou Philipp schlee maria-Magdalena Titirici Dan J.L.Brett Paul R.shearing Rhodri Jervis The Electrochemical Innovation Lab Dept.of Chemical EngineeringUniversity College LondonTorrington PlaceWC1E 7JE LondonUK Queen Mary University of London School of Engineering and Materials ScienceMile End RoadE14NS LondonUK Department of Chemical Engineering University of WaterlooWaterlooCanada Department of Chemical Engineering Imperial College LondonSouth Kensington CampusSW72AZ LondonUK

Electrospinning has been proven as a highly versatile fabrication method for producing nano-structured fibres with controllable morphology,of both the fibres themselves and the void structure of the ***,it is possible to use heteroatom doped polymers or to include catalytic precursors in the electrospinning solution to control the surface properties of the *** factors make it an ideal method for the production of electrodes and flow media for a variety of electrochemical devices,enabling reduction in mass transport and activation overpotentials and therefore increasing ***,the use of biomass as a polymer source has recently gained attention for the ability to embed sustainable principles in the materials of electrochemical devices,complementing their ability to allow an increase in the use of renewable electricity via their *** this review,the historical and recent developments of electrospun materials for application in redox flow batteries,fuel cells,metal air batteries and supercapacitors are thoroughly reviewed,including an overview of the electrospinning process and a guide to best ***,we provide an outlook for the emerging use of this process in the field of electrochemical energy devices with the hope that the combination of tailored microstructure,surface functionality and computer modelling will herald a new era of bespoke functional materials that can significantly improve the performance of the devices in which they are used.

关键词： Electrospinning Redox flow batteries Fuel cells Metal-air batteries supercapacitors

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