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Insular mammalian fauna dynamics and paleogeography:A lesson from the Western Mediterranean islands

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Integrative Zoology 2018年第1期13卷 2-20页

作者： maria Rita PALOMBO Department of Earth Science Sapienza University of RomeRomaItaly CNR-IGAG Monterotondo(Roma)Italy

Since the time of Darwin(1859)and Wallace(1869),islands have been regarded by scientists as a prime target for scrutinizing the forces that may influence evolution and diversification and important elements in biogeographic *** research aims to scrutinize whether and to what extent the composition and structure of past mammal insular faunas and their changes through time may provide sound clues for inferring the paleogeographical evolution of a *** a case study,I critically analyzed the dynamics shown by the Plio-Pleistocene mammalian fauna of 3 Western Mediterranean insular districts,the Balearic Islands,Sardinia and Sicily,each characterized by its own peculiar paleobiogeographical evolutionary *** revision of faunas and the critical analysis of the dispersal ability of the ancestors of island settlers have allowed hypothesizing on the time and mode of island *** results obtained confirm that the early isolation of the Balearic Islands from the mainland led to the establishment of an endemic fauna since the pre-Messinian Miocene(?Astaracian European Land Mammal Age,MN7/8),and that Sardinia has definitely been isolated since the Pliocene,although dispersal events led to some faunal turnovers during the *** addition,the results suggest for Sicily a complex,still imperfectly disentangled history of alternate phases of complete separation and sporadic,more or less difficult connections with southern Italy.

关键词： dispersal islands mammal Plio–Pleistocene Western Mediterranean

On the metallicity gradient in the Galactic disk

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Research in Astronomy and Astrophysics 2020年第4期20卷 123-128页

作者： Alexander Loktin maria Popova Astronomical Observatory Ural Federal UniversityEkaterinburgRussia

The problem of the chemical composition gradient in the Galactic disk is studied based on a sample of metallicity estimates of open star clusters,using Gaia DR2-improved distance estimates.A clearly non-monotonic variation was observed in the average metallicity of clusters with increasing Galactocentric *** can clearly see the metallicity jump of 0.22 in[Fe/H]at a Galactocentric distance of about9.5 kpc,which appears to be linked to the outer boundary of the thinnest and youngest component of the Galactic *** absence of a significant metallicity gradient in the internal(R10 kpc)regions of the disk demonstrates the absence of noticeable metal enrichment at times of the order of the ages corresponding to those of the disk regions under *** data show that the disk experiences noticeable metal enrichment only during the starburst *** significant dependence was identified between the average metallicity and the age of the clusters.

关键词： Galaxy:general Galaxy:disk (Galaxy:)open clusters and associations:general

Nonlinear Korn Inequalities on a Hypersurface

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Chinese Annals of Mathematics,Series B 2018年第3期39卷 513-534页

作者： maria MALIN Cristinel MARDARE Department of Mathematics University of CraiovaCraiova200585Romania Sorbonne Universite CNRSLaboratoire Jacques-Louis LionsLHLLF-75005ParisFrance

The authors establish several estimates showing that the distance in W^(1,p),1 < p < ∞,between two immersions from a domain of R^n into R^(n+1) is bounded by the distance in L^p between two matrix fields defined in terms of the first two fundamental forms associated with each immersion. These estimates generalize previous estimates obtained by the authors and P. G. Ciarlet and weaken the assumptions on the fundamental forms at the expense of replacing them by two different matrix fields.

关键词： Differential geometry Hypersurface Nonlinear shell theory

Perspective on automated in vivo drug screening using the chodl mutant zebrafish line

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Neural Regeneration Research 2022年第11期17卷 2437-2438页

作者： Ana-maria Oprisoreanu Center for Regenerative Therapies Dresden(CRTD) TU Dresden

Since the early 2000s, the popularity of zebrafish in in vivo drug screening has shown a substantial *** zebrafish has become an important screening tool covering a wide range of tissue-specific pathologies and diseas... 详细信息

关键词： fish vivo screening

Xenoestrogens challenge 17β-estradiol protective effects in colon cancer

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World Journal of Gastrointestinal Oncology 2014年第3期6卷 67-73页

作者： maria Marino Department of Science University Roma TreI-00146 RomaItaly

Several epidemiological,cellular,and molecular studies demonstrate the role of environmental chemicals with endocrine disrupting activities,typical of Westernized societies,in the pathogenesis of numerous diseases including *** this information,the design and execution of studies on endocrine disruptors are not yet cognizant that the specific actions of individual hormones often change with development and ageing,they may be different in males and females and may be mediated by different receptors isoforms expressed in different tissues or at different life *** statements are particularly true when assessing the hazard of endocrine disruptors against 17β-estradiol(E2)actions in that this hormone is crucial determinant of sexrelated differences in anatomical,physiological,and behavioral traits which characterize male and female ***,E2 is also involved in *** oncogenic effects of E2 have been investigated extensively in breast and ovarian cancers where hormone-receptor modulators are now an integral part of targeted *** is known about the E2preventive signalling in colorectal cancer,although this disease is more common in men than women,the difference being more striking amongst pre-menopausal women and age-matched *** review aims to dissect the role and action mechanisms of E2 in colorectal cancer evaluating the ability of estrogen disruptors(i.e.,xenoestrogens)in impair these E2 *** discussed here lead to define the possible role of xenoestrogens in the impairment and/or activation of E2signals important for colorectal cancer prevention.

关键词： 17β-Estradiol Estrogen receptors Xenoestrogens Bisphenol A Flavonoids Colorectal cancer

Rare earth elements in flotation products of coals from East Kootenay coalfields,British Columbia

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Journal of Rare Earths 2019年第12期37卷 1366-1372页

作者： Vinoth Kumar Kuppusamy maria Holuszko NBK Institute of Mining Engineering University of British Columbia

With the identification of coal deposits that are enriched in rare earth elements(REEs)across the world,coal and coal by-products are considered as an alternative source for REEs due to the combined supply and demand restrictions for these *** are being conducted to recover these elements from various coal *** this study,coal samples from the East Kootenay coalfields in British Columbia,Canada were examined for the presence of REEs in run-of-mine coal samples and flotation *** reveal that on an ash basis,the concentration of REEs varies from 174 to 1038 mg/kg in the *** understand the REE as sociation,which is essential for extraction purposes,a three-step sequential extraction process along with a mineralogical evaluation using scanning electron microscopy(SEM)with energy dispersive X-ray spectroscopy(EDX)and quantitative X-ray diffraction(XRD)data was *** is found that a significant portion of REEs in the feed samples were reported to middling and tailings *** mineralogical analyses reveal REE association with aluminosilicate mineral in the samples.

关键词： Rare earth elements Coal East Kootenay coalfields Mode of occurrence

Estrogen/Huntingtin:a novel pathway involved in neuroprotection

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Neural Regeneration Research 2016年第3期11卷 402-403页

作者： maria Teresa Nuzzo maria Marino Department of Science-Division of Biomedical Sciences and Technologies University Roma Tre

Neurodegenerative diseases（NDs）include more than 600 disease entities that are characterized by loss of specific neurons located in anatomically related functional areas which progressively lead to motor and cognitive *** pathogenesis of NDs involves mitochondrial dysfunction/oxidative stress,programmed cell death or abnormal protein aggregation,trafficking,and/or *** most cases,

关键词： programmed mitochondrial pathogenesis progressively aggregation oxidative abnormal neuronal caspase physiological

Synthetic gauge fields for ultracold atoms

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National Science Review 2016年第2期3卷 166-167页

作者： Ana maria Rey JILA NIST and Department of PhysicsUniversity of Colorado

Ultracold gases are remarkably versatile and controllable systems with untapped potential to emulate a variety of quantum phenomena[1].Atoms are,however,electrically neutral and therefore it is highly desirable to make them behave as charged *** capability has recently been demonstrated in a series of recent experiments[2-4].Although many challenges remain ahead,

关键词： Synthetic gauge fields for ultracold atoms

Robust Control of a Bevel-Tip Needle for Medical Interventional Procedures

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IEEE/CAA Journal of Automatica Sinica 2020年第1期7卷 244-256页

作者： Surender Hans Felix Orlando maria Joseph Department of Electrical Engineering Indian Institute of Technology RoorkeeRoorkeeUttarakhand 247667India

In minimally invasive surgery, one of the main objectives is to ensure safety and target reaching accuracy during needle steering inside the target organ. In this research work, the needle steering approach is determined using a robust control algorithm namely the integral sliding mode control(ISMC) strategy to eliminate the chattering problem associated with the general clinical scenario. In general, the discontinuity component of feedback control input is not appropriate for the needle steering methodology due to the practical limitations of the driving actuators. Thus in ISMC, we have incorporated the replacement of the discontinuous component using a super twisting control(STC)input due to its unique features of chattering elimination and disturbance observation characteristics. In our study, the kinematic model of an asymmetric flexible bevel-tip needle in a soft-tissue phantom is used to evaluate stability analysis. A comparative study based on the analysis of chattering elimination is executed to determine the performance of the proposed control strategy in real-time needle steering with conventional sliding mode control using vision feedback through simulation and experimental results. This validates the efficacy of the proposed control strategy for clinical needle steering.

关键词： Minimal invasive surgery needle steering nonholonomic system robust control sliding mode control