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Cylindrospermopsin in Water Supply Reservoirs in Brazil Determined by Immunochemical and Molecular Methods

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Journal of Water Resource and Protection 2011年第6期3卷 349-355页

作者： maria do carmo Bittencourt-Oliveira Viviane Piccin-Santos Paula Kujbida Ariadne do Nascimento Moura 不详

It is reported for the first time in Brazil and South America the presence of cylindrospermopsin (CYN) in water supply reservoirs. CYN is a powerful hepatotoxic alkaloid implicated in outbreaks of human sicknesses. We detected CYN in different sources of water in Northeastern Brazil using molecular and immunological techniques. The highest concentrations of toxin occurred in the Jucazinho reservoir with the phytoplankton containing the potentially CYN-producing C. raciborskii and Sphaerospermopsis aphanizomenoides (previously known as Aphanizomenon aphanizomenoides). The polyketide synthase (PKS) and peptide synthetase (PS), which are directly related to the ability to produce CYN, were found in all the analyzed samples. The result of the present study emphasizes the need to improve monitoring of CYN in water bodies used for drinking and recreation, in order to avoid exposure of human populations to this toxin.

关键词： Aphanizomenon Cyanobacteria Cylindrospermopsis Raciborskii CYN Sphaerospermopsis Aphanizomenoides Toxin

Increase in Straight and Coiled Cylindrospermopsis raciborskii (Cyanobacteria) Populations under Conditions of Thermal De-Stratification in a Shallow Tropical Reservoir

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Journal of Water Resource and Protection 2011年第4期3卷 245-252页

作者： maria do carmo Bittencourt-Oliveira Ariadne do Nascimento Moura Talita Caroline Hereman Enio Wocyli Dantas 不详

In recent decades, there have been frequent occurrences of the cyanobacterium Cylindrospermopsis raciborskii in northeastern Brazil. Little is known regarding the response of straight and coiled morphotypes to environmental conditions such as light intensity and water temperature. Samples were collected at the Mundaú reservoir (PE, Brazil) at six sampling depths in the dry and rainy season. Both morphotypes exhibited seasonal and vertical differences in densities. The reservoir was stratified in the dry season, with a predominance of the straight morphotype. The coiled morphotype exhibited greater densities in the lower strata and prove to be more susceptible to light. There was evident thermal de-stratification in the rainy season, with a predominance of the coiled morphotype in the surface layers. Thermal de-stratification favors an increase in both morphotypes by providing adequate conditions for growth, such as low light intensity and milder temperatures, which are characteristic of the winter season in the northeastern Brazil.

关键词： Cyanophyta Light Morphotype Northeastern Brazil Mundaú Reservoir

A Neural Based Modeling Approach for Drying Kinetics Analysis of Mint Branches and Their Fractions (Leaves and Stems)

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Advances in Chemical Engineering and Science 2017年第2期7卷 154-174页

作者： Aline de Holanda Rosanova Gustavo Dias Maia Fábio Bentes Freire maria do carmo Ferreira Graduate Program of Chemical Engineering Federal University of S&atilde o Carlos S&atilde o Carlos Brazil Chemical Engineering Department Federal University of S&atilde o Carlos S&atilde o Carlos Brazil

This work is aimed at investigating regular mint (Mentha × villosa) drying behavior and assessing how the heterogeneous composition of plants affects their drying kinetics. Drying kinetics and sorption isotherms were evaluated for whole branches and their fractions (leaves and stems). Stems and leaves were characterized by measurement of dimensions, apparent density and initial moisture content. The moisture sorption isotherms were obtained under temperatures of 30°C, 40°C and 50°C for branches, stems and leaves and the data were fitted to the GAB model. Mint branches and their fractions were oven dried at temperatures from 40°C to 70°C?and were obtained kinetic curves for each part. Water sorption patterns were similar for leaves and stems and the GAB model described well the sorption behavior of both materials. At a constant temperature, the drying rates were higher for leaves in comparison to stems and the differences increased as the temperature was raised. Therefore, depending on drying conditions, the moisture distribution in dried branches might be significantly different. Since the leaves constitute the major fraction in branches, the drying rates of branches were closer to those of leaves. The kinetic curves were fitted to a diffusion model based on an analytical solution of Fick’s second diffusion law and to an empirical model based on artificial neural network (ANN). The results showed that the model based on the ANN predicted the drying kinetics of the different parts better than the diffusive model. A single network was built to describe the kinetic behavior of branches and fractions in the whole range of temperatures investigated. The diffusive model based on fitting effective diffusivity did not provide good predictions of moisture content, probably because neither the dependence of effective diffusivity on the moisture content nor the heterogeneity and shrinking of static beds were considered.

关键词： Aromatic Herbs Regular Mint Branches Stems Sorption Isotherms Oven Drying Artificial Neural Network

Hydrologic Monitoring Plan of the Brazilian Water Producer/PCJ Project

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Journal of Environmental Protection 2016年第12期7卷 1956-1970页

作者： Denise Taffarello João Guimarães Regiane Kock de Sousa Lombardi maria do carmo Calijuri Eduardo Mario Mendiondo Hydraulics & Sanitary Department Escola de Engenharia de Sao Carlos University of Sao Paulo Sao Carlos Sao Paulo Brazil Fauna and Flora International Biodiversity Partnership Curitiba Paraná Brazil Lombardi Topografia e Agrimensura Curitiba Paraná Brazil Brazilian Center of Monitoring and Early Warning of Natural Disasters (CEMADEN) Sao Jose dos Campos Sao Paulo Brazil

Both Ecosystem-based Adaptation (EbA) and Payment for Ecosystem Services (PES) have a wide range of strategies that include different economic instruments for nature conservation. Although the generation and maintenance of payment for hydrologic ecosystem services (Water-PES) is expanding in Brazil, there are difficulties in the implementation of projects. Due to the complexity and non-linearity of the hydrological processes, also affecting both EbA and Water-PES goals, monitoring quali-quantitative aspects of streams have been here addressed as a useful management tool. This study presents the Hydrological Monitoring Plan (HMP) of the Water Producer/PCJ project, operating between 2009-2014, in order to: 1) evaluate the impact of project actions under water quali-quantitative aspects;and 2) promote the incorporation of HMP’s elements in water resources management. HMP of the Water Producer/PCJ project has been implemented following the conditions for efficiency (baseline, long-term scale compatible with the actions of the project, in the experimental and reference watersheds). In addition, HMP is being implemented from upstream to downstream in catchments with areas ranging from 17 to 130 km2. This proposal favors the quantification and valuation of hydrologic services that could be assessed by ecohydrologic monitoring and modeling. Thus, we look forward to the consolidation of the Brazilian information system of water resources, the reduction of modeling uncertainties and integrated assessment of the consequences of land-use/land-cover change that strongly impact goals of EbA and Water-PES initiatives.

关键词： Ecohydrological Monitoring Brazilian Water Producer/PCJ Project Hydrologic Services Quali-Quantitative Aspects of Water Resources

Risk factors associated with inflammatory bowel disease: A multicenter case-control study in Brazil

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World Journal of Gastroenterology 2020年第25期26卷 3611-3624页

作者： Valéria Cristina Loureiro Salgado Ronir Raggio Luiz Neio Lucio Fernandes Boéchat Isabella Sued Leao Bianca do carmo Schorr JoséMiguel Luz Parente Daniela Calado Lima Eduardo Santos Silveira Júnior Genoile Oliveira Santana Silva Neogélia Pereira Almeida Andrea vieira maria Luiza Queiroz de Bueno Júlio maria Chebli érika Ruback Bertges Luísa Martins da Costa Brugnara Columbano Junqueira Neto Stefania Burjack Gabriel Campbell Luana Letiza Discacciati Joao Paulo Silva Cézar Tiago Nunes Gilaad G Kaplan Cyrla Zaltman Division of Gastroenterology Department of Internal MedicineClementino Fraga Filho HospitalFederal University of Rio de JaneiroRio de Janeiro 21940-230Brazil Institute for Studies in Public Health Federal University of Rio de JaneiroRio de Janeiro 21940-230Brazil Multidisciplinary Research Laboratory Clementino Fraga Filho HospitalInstitute of Thoracic DiseasesFaculty of MedicineFederal University of Rio de JaneiroRio de Janeiro 21940-230Brazil Division of Gastroenterology Department of Internal MedicineHospital UniversityFaculty of MedicineFederal University of PiauíPiauí64049-550Brazil Almeida Division of GastroenterologyInflammatory Bowel Disease Outpatient ClinicRoberto Santos General Hospital(HGRS)of the Bahia State Department of HealthBahia 40110-060Brazil Division of Gastroenterology Inflammatory Bowel Disease Outpatient ClinicIrmandade Santa Casa da Misericórdia of São PauloSão Paulo 01221020Brazil Division of Gastroenterology Department of Internal MedicineHospital UniversityFaculty of MedicineFederal University of Juiz de ForaMinas Gerais 36036-247Brazil Division of Gastroenterology Inflammatory Bowel Disease Outpatient ClinicFederal District Base HospitalBrasília 70330-150Brazil Gastrointestinal Physiology Institute of Nutritional ScienceNestle Research CenterLausanne 1000Switzerland Departments of Medicine and Community Health Sciences University of CalgaryCalgary T2N4Z6Canada

BACKGROUND The etiology of inflammatory bowel disease(IBD)is unknown,but it is believed to be *** hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated *** To test the hygiene hypothesis in IBD by assessing the environmental risk factors associated with IBD development in different regions of Brazil with diverse socioeconomic development *** A multicenter case-control study was carried out with 548 Crohn’s disease(CD)and 492 ulcerative colitis(UC)outpatients and 416 healthy controls,from six IBD centers within different Brazilian states at diverse socioeconomic development stages.A semi-structured questionnaire with 87 socioeconomic and environmental questions was *** regression model was created to assess the odds ratio(OR)with P value and 95%confidence intervals(CI).RESULTS Predictive variables for both diseases(CD and UC)were women[odd ratios(OR)=1.31;OR=1.69],low monthly family income(OR=1.78;OR=1.57),lower number of cohabitants(OR=1.70;OR=1.60),absence of vaccination(OR=3.11;OR=2.51),previous history of bowel infections(OR=1.78;OR=1.49),and family history of IBD(OR=5.26;OR=3.33).Associated risk factors for CD were age(18-39 years)(OR=1.73),higher educational level(OR=2.22),absence of infectious childhood diseases(OR=1.99).The UC predictive variables were living in an urban area(OR=1.62),inadequate living conditions(OR=1.48)and former smokers(OR=3.36).Appendectomy was a risk factor for CD(OR=1.58)with inverse association with UC(OR=4.79).Consumption of treated and untreated water was associated with risk of CD(OR=1.38)and UC(OR=1.53),*** This is the first examining environmental exposures as risk factors for inflammatory bowel disease in *** of the variables associated with disease risk support the role of the hygiene hypothesis in IBD development.

关键词： Crohn’s disease Ulcerative colitis Risk factors Environmental factors Hygiene hypothesis

Hesperidin Reduces Cisplatin-lnduced DNA Damage in Bone Marrow Cells of Mice

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Journal of Pharmacy and Pharmacology 2017年第5期5卷 282-288页

作者： Tatiane da Silva Passos Esdras Andrade Santana Maina Mantovanelli da Mota Jean Carlos Vencioneck Dutra Juliana Macedo Delarmelina maria do carmo Pimentel Batitucci Departamento de Ciencias Biologieas Universidade Federal do Espirito Santo Vitoria 29075-91 Brazil

Hesperidin is a bioflavonoid abundantly found in citrus fruits and displays chemoprotective effects against DNA （deoxyribonucleic acid） damage, however there are few reports about hesperidin effects against cisplatin-DNA damage induction. The aim of this work was to evaluate hesperidin antimutagenicity against cisptatin-DNA damage. （1） The antimutagenicity of hesperidin was assayed by bone marrow of mice in vivo using the micronucleus test. Hesperidin pre-treatment protocol reduced the frequency of MNPCE （micronucleated polychromatic erythrocytes） and the dose of 100 mg·kg-1 was highest efficiency, with 65.24% of damage reduction. In the simultaneous treatment protocol, the dose of 200 mg·kg-1 exhibited a more effective reduction of MNPCE, with 94.01% of damage reduction. （2） Hesperidin was also effective in reducing the MNPCE frequency in the post-treatment protocol for all doses, with 77.48%, 82.13% and 90.08% of damage reduction at the doses of 100, 200 and 400 mg·kg-1, respectively. From the study, it can be concluded that hesperidin was able to promote the reduction of micronuclei frequency and DNA damage induced by cisplatin. Hesperidin is a powerful antioxidant compound and its chemoprotective effects on DNA may occur due to its association with the antioxidant cell system which is responsible for eliminate free radicals generated by chemical harmful to DNA.

关键词： Hesperidin micronucleus test DNA damage chemoprotection antimutagenicity.

Recovery of Scenic Beauty of a Lake in Urban Park from Environmental Diagnosis and Implantation of Mitigating Measures

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Journal of Water Resource and Protection 2019年第5期11卷 595-605页

作者： Joã o Alexandre Saviolo Osti Clovis Ferreira do carmo Marcos Cerqueira maria Teresa Duarte Giamas Ana Carolina Peixoto Cacilda Thais Janson Cacilda Thais Janson Pesquisador Associado ao Instituto de Pesca S&#227 o Paulo Brasil Professor Colaborador à Universidade Brasil Fernand&#243 polis Brasil Centro de Pesquisa em Recursos Hí dricos Instituto de Pesca APTA-SAA S&#227 o Paulo Brasil Pesquisador Cientí fico do Instituto de Pesca S&#227 o Paulo Brasil Aluna PIBIC de Iniciaç o Cientí fica do Instituto de Pesca S&#227 o Paulo Brasil

The city of S?o Paulo, state of S?o Paulo/Brazil, with about 12 million inhabitants is considered the largest city in Latin America. Just as in other large metropolises it is devoid of green areas, in this way it is of great socio-environmental importance of the preservation and maintenance of parks and green areas of the municipality. The Fernando Costa Park, known as the Parque da água Branca, is an urban park located in the central region of the Municipality of S?o Paulo, and has more than 79 thousand m2 of green area, in a total area of 137 thousand m2. Two lakes, populated predominantly with carp, are inserted in the Park, and are important components of the urban landscape and the patrimony of the city, present landscape function (scenic beauty) and are used to contemplate the environment and leisure of the population. The lakes due to the intense eutrophication process with uncontrolled growth of the phytoplankton presented blue-green coloration, with formations of lumps and foams, low transparency, bad smell and unpleasant visual aspect impairing the visitation of this place. In the first stage of the present research, an environmental diagnosis was carried out and the second stage involved elaboration and implementation of mitigating measures aiming at its restoration. The recovery proposal included the implementation of Artificial Floating Islands (IFAs) aiming at pollution control. After 60 days, it was possible to observe the efficiency of the Eichhornia crassipes populated islands showing that the methodology of phytoremediation was efficient in controlling the eutrophication of urban lakes, guaranteeing the recovery and conservation of the scenic beauty of these places.

关键词： Water Quality Eutrophication Pollution Landscape Ecology

Prevalence of Frailty Syndrome in the Elderly and Associated Factors in Brazil

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Health 2015年第11期7卷 1591-1599页

作者： Anna Ferla Monteiro Silva Passos Iris do Céu Clara Costa Fábia Barbosa de Andrade maria do carmo Eulálio Anita Liberalesso Neri Romulo Lustosa Pimenteira de Melo Adrianna Ribeiro Lacerda Postgraduation Program in Health Sciences Federal University of Rio Grande do Norte Natal Brazil Department of Dentistry Federal University of Rio Grande do Norte Natal Brazil Nursing Faculty of Health Sciencies of Trairi/Federal University of Rio Grande do Norte Santa Cruz Brazil Department of Psychology State University of Paraíba Campina Grande Brazil Department of Educational Psychology State University of Campinas Campinas Brazil

This paper aims to identify the prevalence of frailty syndrome and its association with demographic, economic, health, psychological and functional variables in Brazilian population. The study was cross-sectional and composed of 385 elderly aged from 65 years, an average age of 73.92 years. A multivariate Poisson regression was used to check for conditions associated with frailty and to determine the prevalence (α = 0.05). The prevalence of frailty was 8.7% and pre-frailty of 50.4%. The frail and pre-frail older adults showed larger and increasing prevalence ratios for marital status, difficulty performing instrumental activities of daily living, old age, involuntary loss of feces, depression and negative affections. These results can guide the establishment of preventive measures and the development of intervention strategies aimed at minimizing the adverse effects of frailty in elderly people.

关键词： Aging Frail Elderly Frailty Frailty Syndrome

巴西濒危景观“铁四角”地区铁矿石露头对植物多样性的影响

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AMBIO－人类环境杂志 2008年第4期37卷 309-311页

作者： Claudia maria Jacobi Flávio Fonseca do carmo 梁虹（译） Departamento de Biologia Geral Instituto de Ciencias Biológicas Universidade Federal de Minas Gerais Avenida Antonio Carlos 662731270-901 Belo Horizonte -MG 不详

在位于植物多样性中心地带的全球矿藏最丰富的地区，由于生态系统的作用迄今为止仍被忽视，生物多样性和生态系统脆弱性超出了本文图片中的程度。

关键词：植物多样性铁矿石露头景观濒危巴西生态系统生物多样性