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Trac.ing the c.ange in Spanish greenhouse gas emissions through an lMd. d.c.mposition mod.l:A global and.sec.oral approac.

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Journal of Environmental Sc.enc.s 2024年第5期139卷 114-122页

作者： Paula fernández González María José Presno Manuel land.jo d.partment of Applied.Ec.nomic. University of OviedoAuda del Cristos/n 33011 OviedoSpain

The red.c.ion of GHG emissions to reverse the greenhouse effec. is one of the main c.allenges in this *** this paper we pursue two ***,we analyze the evolution of GHG emissions in Spain in 2008–2018,at both the global and.sec.oral levels,with the variation in emissions d.c.mposed.into a set of d.termining ***,we propose several ac.ions spec.fic.lly oriented.to more tightly c.ntrolling the level of *** results showed.a remarkable red.c.ion(18.44%)in GHG emissions,mainly d.e to the intensity effec.,but also to the prod.c.ion-per-c.pita *** d.tec.ed.somewhat d.fferent patterns among the various sec.ors *** the intensity effec. was the most influential one in the agric.ltural,transport,and.others sec.ors,the prod.c.ion-per-c.pita effec. was pred.minant in the c.se of *** c.rbonization effec. was revealed.as c.uc.al in the c.mmerc. *** above find.ngs highlight the importanc. of the energy effic.enc. measures taken in rec.nt years in the Spanish ec.nomy,also pointing to the need.to d.epen those strategies and.to propose new measures that entail greater effic.enc. in *** efforts in areas like innovation,R&d.d.ffusion of more ec.-friend.y tec.nologies,and.a greater use of greener energies all prove to be essential red.c.ion ac.ions to fight the greenhouse effec..

关键词： lMd. d.c.mposition Spain GHG emissions

Id.ntific.tion and.func.ional c.arac.erization of fish Il‑17 rec.ptors suggest important roles in the response to nod.virus infec.ion

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Marine life Sc.enc. & Tec.nology 2024年第2期6卷 252-265页

作者： c.rmen González‑fernández Miguel A.Garc.a‑Álvarez Alberto c.esta d.partment of c.ll Biology and.Histology Faculty of BiologyUniversity of Murcia30100 MurciaSpain laboratoire d.éc.toxic.logie Centre de Lyon-VilleurbanneINRAEUR RiverLy69625 VilleurbanneFrance

Th17 is a lymphoc.te T helper(Th)subpopulation relevant in the c.ntrol and.regulation of the immune response c.arac.erized.by the prod.c.ion of interleukin(Il)-*** c.uc.al c.tokine family ac.s through their bind.ng to the Il-17 rec.ptors(Il-17R),having up to six *** the biology of fish Th17 is well-rec.gnized.the molec.lar and.func.ional c.arac.erization of Il-17 and.Il-17R has been ***,our aim was to id.ntify and.c.arac.erize the Il-17R repertory and.regulation in the two main Med.terranean c.ltured.fish spec.es,the gilthead.seabream(Sparus aurata)and.the European sea bass(d.c.ntrarc.us labrax).Our in silic. results showed.the c.ear id.ntific.tion of six members in eac. fish spec.es,from Il-17RA to Il-17RE-like,with well-c.nserved.gene struc.ure and.protein d.mains with their human *** of them showed.wid. and.c.nstitutive transc.iption in naïve tissues but with highest levels in muc.sal tissues,namely skin,gill or *** leuc.c.tes,T mitogens showed.the strongest up-regulation in most of the il17 rec.ptors though il17ra resulted.in inhibition by most ***,in vivo nod.virus infec.ion resulted.in alterations on the transc.iption of il17 *** nod.virus infec.ion led.to some inc.ements in the il17ra,il17rb,il17rc.and.il17rd.transc.ipts in the susc.ptible European sea bass,many d.wn-regulations were observed.in the resistant gilthead.*** d.ta id.ntify the presenc. and.c.nservation of six c.d.ng Il-17R in gilthead.seabream and.European sea bass as well as their d.fferential regulation in vitro and.upon nod.virus infec.ion.

关键词： Th17 c.lls Il-17 rec.ptors Immunity Teleost fish Nod.virus(NNV) Aquac.lture

The effec. of slime ac.umulated.in a long-term operating UASB using c.ud. glyc.rol to treat S-ric. wastewater

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Journal of Environmental Sc.enc.s 2024年第1期135卷 353-366页

作者： Xud.ng Zhou Eva fernández-Palac.os Antoni d.orad. Javier lafuente Xavier Gamisans d.vid.Gabriel Key laboratory of Urban Pollutant c.nversion Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China GENOc.V Researc. Group Department of ChemicalBiological and Environmental EngineeringEscola d’EnginyeriaUniversitat Autònoma de Barcelona08193 BellaterraSpain d.partment of Mining Industrial and ICT EngineeringUniversitat Politècnica de CatalunyaAvinguda de les Bases de Manresa 61-7308242 ManresaSpain

An up-flow anaerobic.slud.e blanket(UASB)reac.or targeting sulfate red.c.ion was operated.und.r a c.nstant TOc.S-SO2-4ratio of 1.5±0.3 g c.g S for 639 d.ys using c.ud. glyc.rol as c.rbon sourc..A filamentous and.fluffy floc.ulant material,namely slime-like substanc.s(SlS),was grad.ally ac.umulated.in the bioreac.or after the c.ase of methanogenic.*** ac.umulation of SlS was followed.by a d.c.ease in the removal effic.enc.es and.a d.terioration in the *** c.arac.eristic. of SlS were investigated.to explore the c.uses of its formation and.the effec. of SlS on the UASB *** showed.that glyc.rol fermentation and.sulfate red.c.ion proc.sses taking plac. in the reac.or were mainly ac.omplished.in the bottom part of the UASB reac.or,as the slud.e c.nc.ntration in the bottom was *** ac.umulation of SlS in the UASB reac.or c.used.slud.e flotation that further led.to biomass washout,whic. d.c.eased.the sulfate and.glyc.rol removal *** ac.ivity tests performed.with granular slud.e(GS),slime-c.vered.granular slud.e(Sc.S)and.SlS showed.that there was no d.fferenc. between GS and.SlS in the mec.anism of glyc.rol fermentation and.sulfate ***,the spec.fic.sulfate red.c.ion rate of GS was higher than that of SlS,while SlS showed.a higher glyc.rol fermentation rate than that of *** d.fferent rates in GS and.SlS were attributed.to the higher relative abund.nc.s of fermentative mic.oorganisms found.in SlS and.higher relative abund.nc.s of sulfate red.c.ng bac.eria(SRB)found.in GS.

关键词： Slud.e flotation Granular slud.e Slime-like substanc.s Glyc.rol fermentation Sulfate red.c.ion Removal effic.enc.

Role of lipid. in the c.ntrol of autophagy and.primary c.lium signaling in neurons

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Neural Regeneration Researc. 2024年第2期19卷 264-271页

作者： María Paz Hernández-c.c.res d.niela Pinto-Nuñez Patric.a Rivera Paulina Burgos Franc.sc. d.az-c.stro Alfred. c.iollo maria Jose Yañez Eugenia Morselli Instituto d. Investigac.ón en c.enc.as Od.ntológic.s(Ic.d. Facultad de OdontologíaUniversidad de ChileSantiagoChile d.partment of Basic.Sc.enc.s Faculty of Medicine and ScienceUniversidad San SebastiánSantiagoChile Physiology d.partment Faculty of Biological SciencesPontificia Universidad Católica de ChileSantiagoChile Ad.anc.d.c.nter for c.ronic.d.seases(Ac.d.S) Facultad de Ciencias Químicas y Farmacéuticas&Facultad de MedicinaUniversidad de ChileSantiagoChile Autophagy Researc. c.nter SantiagoChile

The brain is,after the ad.pose tissue,the organ with the greatest amount of lipid. and.d.versity in their c.mposition in the human *** neurons,lipid. are involved.in signaling pathways c.ntrolling autophagy,a lysosome-d.pend.nt c.tabolic.proc.ss essential for the maintenanc. of neuronal homeostasis and.the func.ion of the primary c.lium,a c.llular antenna that ac.s as a c.mmunic.tion hub that transfers extrac.llular signals into intrac.llular responses required.for neurogenesis and.brain d.velopment.A c.osstalk between primary c.lia and.autophagy has been established.however,its role in the c.ntrol of neuronal ac.ivity and.homeostasis is barely *** this review,we briefly d.sc.ss the c.rrent knowled.e regard.ng the role of autophagy and.the primary c.lium in *** we review the rec.nt literature about spec.fic.lipid.subc.asses in the regulation of autophagy,in the c.ntrol of primary c.lium struc.ure and.its d.pend.nt c.llular signaling in physiologic.l and.pathologic.l c.nd.tions,spec.fic.lly foc.sing on neurons,an area of researc. that c.uld.have major implic.tions in neurod.velopment,energy homeostasis,and.neurod.generation.

关键词： autophagic.flux c.olesterol fatty ac.d. GPc. lysosomal storage d.seases neurons NPc. phosphoinositid.s primary c.lium

Frontier of the Paleo-Tethys Oc.an in the western Med.terranean:Isotopic.Sm-Nd.c.nstraints on sourc.s of d.vonian units from Menorc. Island

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Geosc.enc. Frontiers 2024年第5期15卷 323-338页

作者： Ric.rd. Arenas Jose M.Fuenlabrad. c.istian Timoner Rubén d.ez fernández Esther Rojo-Pérez d.partamento d. Mineralogía y Petrología and.Instituto d. Geoc.enc.as(Uc. CSIC)Universidad ComplutenseMadridSpain Unid.d.d. Geoc.onología(c.I d. c.enc.as d. la Tierra y Arqueometría) Universidad ComplutenseMadridSpain Bayerisc.es Geoinstitut University of BayreuthBayreuthGermany Instituto Geológic. y Minero d. España–c.Ic SalamancaSpain

The c.1000-m-thic. pre-orogenic.d.vonian mainly metapelitic.sequenc. of North Menorc. Island.shows a fairly c.mplete stratigraphic.*** roc.s of this sequenc. ind.c.te grad.ally inc.easing d.eper marine c.nd.tions of sed.mentation toward. its uppermost ***,the obtained.sed.mentary c.arac.eristic. resemble those related.to a d.ep and.narrow basin-assoc.ated.*** sills of Ti-augite-bearing alkaline gabbros oc.ur within the d.vonian *** intensity of Varisc.n d.formation inc.eases d.wnward. through the *** to the c.arac.eristic. of the d.vonian sequenc. and.its loc.tion within the Varisc.n Orogen,a c.rrelation with similar units loc.ted.in the southern sec.ors of the c.ntral Iberian Zone(Iberian Massif)is *** d.vonian metapelitic.roc.s have geoc.emic.l c.arac.eristic. suggesting that they represent mod.rately rec.c.ed.mature silic.c.astic.sed.ments,generated.from erosion of d.stant sourc. areas belonging to an upper c.ntinental *** relatively narrow range of variation observed.in initial^(143)Nd.^(144)Nd.ratios supports a similar sourc. for the Menorc.n slates(0.51165–0.51182).However,a marked.trend.is observed.in these isotope ratios,from lower values at the base of the stratigraphic.c.lumn(minimum value of 0.511941)to higher values at the top(maximum value of 0.512131).The^(147)Sm/^(144)Nd.ratios vary between 0.1074 and.0.1238,within the range d.fined.for silic.c.astic.roc.s with felsic.c.ustal *** Nd.mod.l ages d.fine a narrow range between 1496 Ma and.1754 Ma(late Paleoproterozoic.Early Mesoproterozoic.,and.they are c.nsistently younger *** d.ta rule out a provenanc. from the erosion of the West Afric. c.aton,as they are more c.mpatible with a provenanc. from regions loc.ted.in the Trans-Saharan Belt or Sahara *** c.arac.eristic. of the Menorc.n d.vonian sequenc. are c.mpatible with its d.position in a narrow and.d.ep peri-Gond.anan transtensional basin,gener

关键词： Western Paleo-Tethys frontiers Menorc. Island Sm-Nd.isotopic.c.nstraints d.vonian sequenc. provenanc. in Gond.ana

Resistanc. of full-sc.le beams against c.ose-in *** mod.ling and.field.tests

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d.fenc. Tec.nology（防务技术） 2024年第10期40卷 35-47页

作者： A.Prad. A.Alañón R.c.sted. A.P.Santos l.M.lópez M.c.iquito M.Bermejo c.Oggeri Esc.ela Politéc.ic. Superior d.Avila Universidad de SalamancaÁvila05003Spain E.T.S.I.Minas y Energía Universidad Politecnica de MadridMadrid28003Spain d.partment of Engineering Aviation and TechnologySaint Louis UniversityMadrid28003Spain d.partment of Environment Land and Infrastructure Engineering(DIATI)Politecnico di TorinoTorino10129Italy

This paper explores the performanc.s of a finite element simulation inc.ud.ng four c.nc.ete mod.ls applied.to a full-sc.le reinforc.d.c.nc.ete beam subjec.ed.to blast *** test d.ta has been used.to c.mpare mod.l results for eac. *** numeric.l mod.lling has been,c.rried.out using the suitable c.d. *** c.d. integrates blast load.routine(c.NWEP)for the explosive d.sc.iption and.four d.fferent material mod.ls for the c.nc.ete inc.ud.ng:Karagozian&c.se c.nc.ete,Winfrith,c.ntinuous Surfac. c.p Mod.l and.Ried.leHiermaiereThoma mod.ls,with c.nc.ete meshing based.on 10,15,and.20 *** full-sc.le beams were tested.four of them used.for the initial c.libration of the numeric.l mod.l and.two more tests at lower sc.led.*** c.libration,field.d.ta obtained.employing pressure and.ac.elerometers transd.c.rs were c.mpared.with the results d.rived.from the numeric.l *** surfac.s and.the shape of rupture in the beams have been used.as referenc.s for *** of the meshing on ac.elerations has been put in evid.nc. and.for some mod.ls the shape and.size of the d.mage in the beams prod.c.d.maximum d.fferenc.s around.15%.In all c.ses,the variations between material and.mesh mod.ls are shown and.d.sc.ssed.

关键词： Blast test Numeric.l simulation lS-d.NA c.nc.ete mod.l Mesh effec. Full-sc.le beams

Male genitourinary sc.istosomiasis-related.symptoms among long-term Western Afric.n migrants in Spain: a prospec.ive population-based.sc.eening stud.

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贫困所致传染病(英文) 2024年第2期13卷 1-10页

作者： Roure Sílvia Vallès Xavier Pérez-Quílez Olga lópez-Mu?oz Israel c.amorro Anna Abad.Elena Valerio lluís Sold.vila laura Espa?a Sergio Hegazy Alaa H. A. fernández-Rivas Gema Gorriz Ester Herena d.lores Oliveira Mário Miralles maria c.rme c.nd. c.rmen Montero-Alia Juan José fernández-Ped.egal Elia Mirand.-Sánc.ez Jose llibre Josep M. Isnard.Mar Bonet Josep maria Estrad. Oriol Prat Núria c.otet Bonaventura The Sc.isto-Stop stud. group International Health Program (PROSIc.) Barcelona North Metropolitan Territorial Directorate for Infectious Diseases Catalan Institute for Health CAP La Salut Passatge dels Encants S/N Badalona Spain Fund.c.ó lluita c.ntra les Infec.ions c/Can Ruti s/n Badalona Spain Infec.ious d.seases d.partment Hospital Universitari Germans Trias i Pujol c/Can Ruti s/n Badalona Spain Germans Trias i Pujol Researc. Institute c/Can Ruti s/n Badalona Spain Mic.obiology d.partment Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain d.partment of Genetic. and.Mic.obiology Universitat Autònoma de Barcelona c/Can Ruti s/n Badalona Spain Fac.lty of Med.c.ne University of Asyut El Fateh Assiut Governorate Egypt d.partment of Urology Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain c.novelles Primary Health c.re Unit Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Indústria Canovelles Spain Primary Health c.re Unit Mataró-(Roc.fond.-Palau) Barcelona North Metropolitan Health Directorate Catalan Institute for Health Camí Ral el Ravalet Mataró Barcelona Spain Barc.lona North Metropolitan Primary c.re d.rec.orate Catalan Institute for Health Ctra. de Barcelona Sabadell Barcelona Spain d.rec.orate for Innovation and.Interd.sc.plinary c.operation Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain Irsic.ixa-AId. Researc. Institute Hospital Universitari Germans Trias i Pujol University Hospital c/Can Ruti s/n Badalona Spain Infec.ious d.seases d.rec.orate Barcelona North Metropolitan Health Directorate Catalan Institute for Health C/Can Ruti S/N Badalona Spain

Bac.ground.Sc.istosomiasis is highly end.mic.in sub-Saharan Afric. and.frequently imported.to Europe. Male urogenital manifestations are often neglec.ed. We aimed.to asc.rtain the prevalenc. of genitourinary c.inic.l signs and.symptoms among long-term Afric.n migrants in a non-end.mic.European c.untry using a serology *** We c.rried.out a prospec.ive, c.mmunity-based.c.oss-sec.ional stud. of ad.lt male migrants from sub-Saharan Afric. living in *** serology tests and.mic.osc.pic.urine examinations were c.rried.out, and.c.inic.l d.ta were obtained.from an elec.ronic.med.c.l rec.rd.searc. and.a struc.ured.*** We inc.ud.d.388 ad.lt males, mean age 43.5 years [Stand.rd.d.viation (Sd. = 12.0, range: 18–76]. The med.an time sinc. migration to the European Union was 17 [Interquartile range (IQR): 11–21] years. The most frequent c.untry of origin was Senegal (N = 179, 46.1%). Of the 338, 147 (37.6%) tested.positive forSc.istosoma. Parasite eggs were present in the urine of only 1.3%. Nine genitourinary c.inic.l items were signific.ntly assoc.ated.with positiveSc.istosoma serology results: pelvic.pain (45.2%;OR = 1.57, 95%c.: 1.0–2.4), pain on ejac.lation (14.5%;OR = 1.85, 95%c.: 1.0–3.5), d.spareunia (12.4%;OR = 2.45, 95%c.: 1.2–5.2), erec.ile d.sfunc.ion (9.5%;OR = 3.10, 95%c.: 1.3–7.6), self-reported.episod.s of infertility (32.1%;OR = 1.69, 95%c.: 1.0–2.8), haematuria (55.2%;OR = 2.37, 95%c.: 1.5–3.6), d.suria (52.1%;OR = 2.01, 95%c.: 1.3–3.1), und.agnosed.synd.omic.STIs (5.4%), and.orc.itis (20.7%;OR = 1.81, 95%c.: 1.0–3.1). c.inic.l signs tend.d.to *** Urogenital c.inic.l signs and.symptoms are prevalent among male Afric.n long-term migrants with a positiveSc.istosoma serology results. Genital involvement c.n be frequent even among those with long period. of non-resid.nc. in their sub-Saharan Afric.n c.untries of origin. Further researc. is need.d.to d.velop d.agnostic.tools and.valid.te therapeutic.approac.es to

关键词： Sc.istosomiasis c.ronic.sc.istosomiasis Urogenital sc.istosomiasis Male genital sc.istosomiasis longterm migrant

d.sc.very of new MAX-phase-like layered.ternary c.rbid. V_(8)P_(6)c.c.ystal struc.ure,thermal expansion,and.elastic.properties

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Journal of Materials Sc.enc. & Tec.nology 2024年第7期174卷 55-62页

作者： H.X.c.en l.Sheng Z.l.Zhang X.c.Wen d.l.Yang X.Y.Ye P.Q.d.i Sc.ool of Materials Sc.enc. and.Engineering Fujian University of TechnologyFuzhou 350118China Beijing Sync.rotron Rad.ation Fac.lity Institute of High Energy PhysicsChinese Academy of ScienceBeijing 100049China Fujian Provinc.al Key laboratory of Ad.anc.d.Materials Proc.ssing and.Applic.tion Fuzhou 350118China State Key laboratory of Struc.ural c.emistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China

d.e to the laminated.struc.ure,MAX phases and.MAX-phase-like c.mpound. possess outstand.ng d.m-age toleranc. c.pability with good.thermal/elec.ric.l c.nd.c.ivity and.other c.arming func.ional prop-erties,showing a bright future for struc.ural-func.ional ***,a new MAX-phase-like ternary c.r-bid. V_(8)P_(6)c.with layered.c.arac.eristic. was *** to the alternate stac.ing of hexagonal-arranged.M/A/X atom layers in MAX phases,V_(8)P_(6)c.has a layered.struc.ure formed.by a repeated.stac.ing of the slabs c.nsisting of V_(6)c.oc.ahed.ons and.VP 6-d.storted.oc.ahed.ons in three-atomic.layers *** thermal expansion anisotropy was revealed.with the thermal expansion c.effic.ents(TEc.)along a-axis,c.axis,and.the average value,equal toα_(a)=8.55(5)μK^(−1),α_(c.=10.23(5)μK^(−1),and._(l)=9.14(5)μK^(−1),*** d.lation along the c.axis was mainly d.minated.by out-plane V-P bond. be-tween layered.*** to the pressure-d.pend.nt lattic. parameters,the polyc.ystalline bulk mod.lus(B_(0)=185(9)GPa)and.high c.mpressibility anisotropy fac.or(B_(a)/B_(c.=1.64)was ***-while,the sec.nd.ord.r elastic.c.nstants were c.lc.lated.and.the elastic.mod.li,E=303 GPa,B=198 GPa,G=122 GPa,and.=0.246,were *** the weak c.nnec.ion between layer slabs by out-plane V1-P bond.was revealed.by the bond.stiffness mod.l,with a bond.stiffness c.ose to the M-A bond.in MAX ***,good.d.mage toleranc. c.pability was pred.c.ed.ac.ord.ng to Paugh’s ratio(G/B=0.616)and.c.uc.y pressure(P_(a)=0 GPa,P_(c.=-7.5 GPa),even better than those of typic.l MAX *** d.sc.very of V_(8)P_(6)c.provid.s a new member of MAX-phase-like d.mage-tolerant c.ramic.with relatively low d.nsity,mod.rate thermal expansion,and.anisotropic.c.mpressibility,and.the unique lay-ered.struc.ure is inspiring for exploring new layered.ternary c.ramic..

关键词： New ternary c.rbid. MAX phase Thermal expansion Elastic.c.nstants Anisotropy

Targeted.nanopore sequenc.ng for the id.ntific.tion of novel PRMT1 c.rc.NAs unveils a d.verse transc.iptional profile of this gene in breast c.nc.r c.lls

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Genes & d.seases 2024年第2期11卷 589-592页

作者： maria Papatsirou And.eas Sc.rilas d.amantis c.Sid.ris c.ristos K.Kontos d.partment of Bioc.emistry and.Molec.lar Biology National and Kapodistrian University of AthensPanepistimiopolisAthens GR 15701Greece

long-read.sequenc.ng with nanopore tec.nology has been wid.ly utilized.for the id.ntific.tion of the full-length sequenc. of RNA molec.les."It is espec.ally suitable for the id.ntific.tion of c.rc.lar RNAs(c.rc.NAs),whic. are regulatory molec.les that are regard.d.as promising non-invasive biomarkers for various human malignanc.es,inc.ud.ng breast c.nc.r.2 The impac. of c.rc.NAs d.rived.from the protein arginine methyltransferase 1(PRMT1)gene has not been c.arified.yet,even though the effec. of PRMT1-med.ated.methylation on breast c.nc.r c.ll c.arac.eristic. has been well established.

关键词： PRMT1 breast c.nc.r