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A High-Performance Solid-State Na–CO_(2)Battery with Poly(Vinylidene Fluoride-co-Hexafluoropropylene)−Na_(3.2)Zr_(1.9)Mg_(0.1)Si_(2)PO_(12)Electrolyte

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Energy & Environmental Materials 2023年第3期6卷 87-95页

作者： Liang Lu Chunwen Sun Jian Hao Zelin Wang Sergio F.Mayer maria teresa fernandez-diıaz Jose Antonio Alonso Bingsuo Zou School of Chemical&Environmental Engineering China University of Mining and Technology-BeijingBeijing 100083China School of Physical Science and Technology Guangxi UniversityNanning 530004China State Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering Ningxia UniversityYinchuan 750021China Instituto de Ciencia de los Materiales de Madrid CSICE-28049Cantoblanco-MadridSpain Institut Laue Langevin Grenoble F-38042France Guangxi Key Lab of Processing for Nonferrous Metals and Featured Materials and Key lab of new Processing Technology for Nonferrous Metals and Materials Ministry of EducationSchool of ResourcesEnvironments and MaterialsGuangxi UniversityNanning 530004China

The recovery and utilization of carbon dioxide(CO_(2))is the key to achieve the targets of peak carbon dioxide emissions and carbon *** Na-CO_(2)battery made with cheap alkali metal sodium and greenhouse gas CO_(2)is an effective strategy to consume CO_(2)and store clean renewable ***,the liquid electrolyte volatilization in the open battery system and inevitable dendrite growth restrict the application of Na-CO_(2)*** this work,magnesium-doped Na_(3)Zr_(2)Si_(2)PO_(12)(NZSP)was studied as a solid electrolyte for solid-state Na-CO_(2)*** ionic conductivity of Na_(3.2)Zr_(1.9)Mg_(0.1)Si_(2)PO_(12)reaches 1.16 mS cm^(−1)at room temperature by replacing Zr ions in Na_(3.2)Zr_(1.9)Mg_(0.1)Si_(2)PO_(12)with Mg ions,and the structural changes are analyzed by neutron powder *** composite electrolyte consisting of highly conductive Na_(3.2)Zr_(1.9)Mg_(0.1)Si_(2)PO_(12)and high processability poly(vinylidene fluoride-co-hexafluoropropylene)(PVDF-HFP)is utilized for the first time to assemble a solid-state Na-CO_(2)*** cell shows a full discharge capacity of 7720 mAh g^(−1)at 200 mA g^(−1).The middle gap voltage is lower than 2 V after 120 cycles at 200 mA g^(−1)and at a cut-off capacity of 500 mAh g^(−1).This work demonstrates a promising strategy to design high-performance solid-state Na-CO_(2)batteries.

关键词： cycling stability ion transport Mg-doped NZSP neutron powder diffraction solid-state Na-CO_(2)batteries

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Ni-based catalysts obtained from perovskites oxides for ethanol steam reforming

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燃料化学学报 2018年第11期46卷 1332-1341页

作者： Fabiola Nerina Agüero Jose Antonio Alonso maria teresa Fernández-Díaz Luis Eduardo Cadus Instituto de Investigaciones en Tecnología Química(INTEQUI) UNSL-CONICETAlmirante Brown 14555700 San LuisArgentina Instituto de Ciencia de Materiales de Madrid Consejo Superior de Investigaciones CientíficasCantoblanco28049 MadridSpain Institut Laue-Langevin B.P.156F-38042 Grenoble Cedex 9France

Perovskites as host structures of cations were used in order to generate in situ active and stable catalysts for ethanol steam reforming. For this purpose,La_(1-x)Mg_xAl_(1-y)Ni_yO_3(x = 0.1; y = 0,0.1,0.2,0.3) perovskites were synthetized by the citrate *** segregation is evident for a substitution level higher than 0. 2. The segregation of Ni as NiO generated species interacts with different metal-support after the reduction step. The y = 0.1 catalyst presents the highest H_2 yield value about 85% during reaction time,with low mean values of CH_4 and CO selectivities of 3.4% and 11%,respectively and a low carbon formation. The better performance of y = 0.1 catalyst could be attributed to the minor proportion of segregated phases,thus a controlled expulsion of Ni is successfully reached.

关键词： perovskites catalyst design ethanol steam reforming

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The plasticity of plasticity:lesson from remote microglia induced by focal central nervous system injury

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Neural Regeneration Research 2020年第1期15卷 57-58页

作者： maria teresa Viscomi Institute of Histology and Embriology Università Cattolica del S.Cuore

The last decades have represented an important season in the re-conceptualization of brain plasticity,especially in extending the concept at events occurring beyond the developmental stage and in demonstrating the profound impact of these changes on so-called spontaneous recovery after central nervous system(CNS)*** study of the cellular,molecular,functional and structural mechanisms involved in brain plasticity has clearly emphasized the multitude of players engaged in this phenomenon,leading to the conceptualization that non-neuronal cells and non-neuronal mechanisms intervene in these changes and orchestrate some of the responses observed(Werner and Stevens,2015).Among the different non-neuronal cells and non-neuronal substrates of injury-induced plasticity is becoming increasingly recognized that microglia drive a series of intrinsic CNS responses after damage(Sandvig et al.,2018;Bisicchia et al.,2019).

关键词： plasticity system injuries

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Systematic review: Renin-angiotensin system inhibitors in chemoprevention of hepatocellular carcinoma

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World Journal of Gastroenterology 2019年第20期25卷 2524-2538页

作者： Michele Barone maria teresa Viggiani Giuseppe Losurdo mariabeatrice Principi Alfredo di Leo Gastroenterology Section Department of Emergency and Organ Transplantation University of Bari Aldo Moro

BACKGROUND Neoangiogenesis is one of the key pathogenetic mechanisms in hepatocellular carcinoma (HCC). Modulation of the renin-angiotensin system (RAS) by angiotensin-converting enzyme inhibitors (ACE-Is) and angiotensin receptor blockers (ARBs) seems to be a possible adjuvant therapy for HCC, due to the antiangiogenic and anti-fibrogenic activity of these drugs. AIM To elucidate the role of ARBs and ACE-Is in HCC. METHODS We performed an electronic search of the literature using the most accessed online databases (PubMed, Cochrane library, Scopus and Web of Science), entering the query terms "angiotensin-converting enzyme inhibitors" OR "ACE inhibitors" OR "ACE-I" AND "hepatocarcinoma*" OR "hepatocellular carcinoma;moreover "angiotensin II type 1 receptor blockers" OR "ARBs" AND "hepatocarcinoma*" OR "hepatocellular carcinoma". Eligibility criteria were:(1) prospective or retrospective clinical studies;(2) epidemiological studies;and (3) experimental studies conducted in vivo or in vitro. Abstracts, conference papers, and reviews were excluded a priori. We limited our literature search to articles published in English, in peer-reviewed *** Thirty-one studies were selected. Three interventional studies showed that ACEIs had a significant protective effect on HCC recurrence only when used in combination with vitamin K or branched chain aminoacids, without a significant increase in overall survival. Of six retrospective observational studies, mainly focused on overall survival, only one demonstrated a prolonged survival in the ACE-Is group, whereas the two that also evaluated tumor recurrence showed conflicting results. All experimental studies displayed beneficial effects of RAS inhibitors on hepatocarcinogenesis. Numerous experimental studies, conducted either on animals and cell cultures, demonstrated the anti-angiogenetic and antifibrotic effect of ACE-Is and ARBs, thanks to the suppression of some cytokines such as vascular endothelial growth factor

关键词： Cirrhosis Renin Angiotensin Survival Cancer prevention Hepatocarcinoma

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Lesson from an intriguing case of cryoglobulinemia

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World Journal of Gastroenterology 2013年第2期19卷 304-306页

作者： Michele Barone Raffaele Licinio Annabianca Amoruso maria teresa Viggiani Angela maria Vittoria Larocca Alfredo di Leo Department of Emergency and Organ Transplantation University of Bari70100 BariItaly Department of Biomedical Science and Human Oncology University of Bari70100 BariItaly

Cryoglobulinemia is a pathological condition usually associated with hepatitis C virus(HCV) chronic liver disease and less commonly with autoimmune or lymphoproliferative *** possible association of cryoglobulinemia with hepatitis B virus(HBV) infection is not widely *** our patient,serum negativity for HCV markers initially led us to consider two other causes of *** disorders were excluded on the basis of hematological studies,while serum markers for active HBV infection were ***,the detection of HCV RNA in the cryocrit,even in the absence of anti-HCV antibodies suggested a pathogenetic role of HCV in this case of *** "first level" tests for HCV in the serum do not completely exclude HCV involvement in the pathogenesis of *** of the cryoprecipitate is always essential for diagnosis.

关键词： Cryocrit Hepatitis B virus Hepatitis C virus Myelodysplastic disorders Cryoglobulinemia

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Early life stress-induced neuroinflammation and neurological disorders: a novel perspective for research

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Neural Regeneration Research 2022年第9期17卷 1971-1972页

作者： Clarissa Catale Valeria Carola maria teresa Viscomi division of Experimental Neuroscience IRCCS Santa Lucia FoundationRomeItaly Department of Dynamic and Clinical Psychology and Health StudiesSapienza University of RomeRomeItaly Department of Life Science and Public Health Section of Histology and EmbryologyUniversitàCattolica del S.CuoreRomeItaly

Childhood maltreatment(CM)has been consistently linked with numerous detrimental outcomes concerning physical and psychological ***,few studies have explored vulnerability to neurological disorders after *** life adversity,in the form of poverty,stress and abuse,has been associated with decline in cognitive function and dementia later in life(Short and Baram,2019).Robust preclinical data suggest that early life stress(ELS)may increase the risk and worsen the course of neurological disorders such as Alzheimer’s(AD)and Parkinson’s(PD)diseases,and traumatic brain injury(TBI)(Lesuis et al.,2018;Short and Baram,2019;He et al.,2020;Catale et al.,2021;Sanchez et al.,2021).

关键词： neurological disorders inflammation

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Setting a highway for converting skin into neurons

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Journal of Molecular Cell Biology 2011年第6期3卷 322-323页

作者： Vania Broccoli Massimiliano Caiazzo maria teresa Dell’Anno San Raffaele Scientific Institute Via Olgettina 58Milan 20132Italy

direct conversion of human skin fibroblasts into induced neuronal(iN)cells has been recently achieved by using different combi-nations of transcription factors eventually associated with *** findings lay the ground for a straightforward and effi-cient generation of human neurons in vitro with elaborated functional properties instrumental for disease modeling and cell-based approaches of brain repair.

关键词： eventually straight finding

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Reviewing the discoverability and accessibility to data and information products linked to Essential Climate Variables

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International Journal of digital Earth 2020年第2期13卷 236-252页

作者： maria teresa Miranda Espinosa Gregory Giuliani Nicolas Ray Institute for Environmental Sciences enviroSPACE labUniversity of GenevaGenevaSwitzerland Institute for Environmental Sciences GRID-GenevaUniversity of GenevaGenevaSwitzerland GeoHealth Group Institute of Global HealthFaculty of MedicineUniversity of GenevaGenevaSwitzerland'

Essential Climate Variables(ECVs)are geophysical records generated from systematic Earth Observations associated with climate variations,changes,and *** products support the data and information needs of international frameworks and policies such as the work of the United Nations Framework Convention on Climate Change(UNFCCC)and the Intergovernmental Panel on Climate Change(IPCC).We map the main networks and initiatives publishing ECVs,by presenting an overview of existing satellite-based ECVs,their general data creation characteristics,discoverability and accessibility methods from an end-user *** investigate key initiatives providing or coordinating access to ECV data records,such as the Global Climate Observing System(GCOS),the Committee on Earth Observation Satellites(CEOS),the Coordination Group for Meteorological Satellites(CGMS),Joint Working Group on Climate(WGClimate),the Remote Sensing Systems(REMSS),and the European Space Agency Climate Change Initiative(ESA CCI).We find that ECV data discovery and access is difficult and time consuming due to the lack of common data and metadata *** addition,the selection of fit-for-purpose data records by end-users requires the implementation of interoperable standards and scalable data infrastructures to allow the generation of tailored applications and datadriven information products in support of decision-making processes.

关键词： Essential Climate Variables Climate services discoverability accessibility usability

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Nilotinib:from animal-based studies to clinical investigation in Alzheimer's disease patients

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Neural Regeneration Research 2023年第4期18卷 803-804页

作者： Annalisa Nobili Marcello D’Amelio maria teresa Viscomi Department of Medicine and Surgery University Campus Bio-MedicoDepartment of Experimental NeuroscienceIRCCS Santa Lucia FoundationRomeItaly Department of Life Science and Public Health Section of Histology and Embryology UniversitàCattolica del Sacro CuoreFondazione Policlinico Universitario“A.Gemelli”IRCCSRomeItaly

Since their first description in the brains of patients suffering from Alzheimer ’s disease(AD), more than 100 years ago, extracellular amyloid-β(Aβ) plaques and intracellular neurofibrillary tangles have been the principal focus of AD research. However, this focus has led to the failure of several long and promising clinical trials, and the efficacy of new Aβ-targeting drugs to slow down the disease progression is still controversial despite being successful in reducing the Aβ load.

关键词： Alzheimer Aβ drugs

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Taeniasis vs cysticercosis infection routes

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Asian Pacific Journal of Tropical Medicine 2016年第6期9卷 599-600页

作者： maria teresa Galán-Puchades Department of Cell Biology and Parasitology Faculty of Pharmacy University of Valencia

Although cysticercosis caused by Taenia solium(T. solium) is considered a neglected disease, its life cycle has been well known for more than two centuries. T. solium not only causes cysticercosis but also taeniasis in humans. These two diseases have totally different infection routes. To acquire taeniasis(the presence of the adult stage of T. solium in the intestine), humans have to ingest the larval stage(cysticercus) that infects a variety of organs and viscera in pigs, its intermediate hosts. Therefore, taeniasis is acquired when eating raw or undercooked infected pork. The adult stage in the human intestine release eggs that contain a hexacanth embryo, the oncosphere. If humans accidentally ingest the eggs of T. solium, the released oncospheres penetrate the intestine and become cysticerci. Therefore, cysticercosis is acquired by the ingestion of eggs that contaminate water, vegetables, hands etc. These facts should not be forgotten to avoid misinformation in scientific publications.

关键词： Taeniasis Cysticercosis Infection routes

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