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Cancer Biology & Medicine 2015年第1期12卷 41-45页

作者： Marcelo Corti maria Villafa?e Gonzalo Minue Ana Campitelli Marina Narbaitz Leonardo Gilardi HIV/AIDS Department F.J.Mu?iz Hospital Hematology Unit F.J.Mu?iz Hospital Histopathology Laboratory F.J.Mu?iz Hospital National Academy of Medicine Histopathology Laboratory Sociedad Iberoamericana de Informacion Cientifica Scientific Coordination

Objective： To study the main clinical and histopathological features of 12 patients with Hodgkin＇s lymphoma （HL） diagnosed primarily from bone marrow （BM） involvement. Methods： We included 12 acquired immunodeficiency syndrome （AIDS） patients with HL assisted in the F. J. Mufiiz Infectious Diseases Hospital since January 2002 to December 2013. The diagnosis of ilL with primary BM involvement in patients was confirmed by clinical, histopathological, and immunohistochemical findings. Results： All patients presented ＂B＂ symptoms and pancytopenia. All of them had stage IV neoplasm disease because of BM infiltration. The median of CD4＋ T-cell counts was 114 cells/μL, and mixed cellularity （MC） was the most frequent histopathological subtype of 92% cases. Conclusion： When other causes are excluded, BM biopsy should be performed in AIDS patients with ＂B＂ symptoms and pancytopenia to evaluate BM infiltration by atypical lymphocytes.

关键词： Acquired immunodeficiency syndrome (AIDS) Hodgkin's lymphoma (HL) bone marrow (BM)

Role of scintigraphy in inflammatory bowel disease

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World Journal of Gastroenterology 2009年第22期15卷 2693-2700页

作者： maria I Stathaki Sophia I Koukouraki Nikolaos S Karkavitsas Ioannis e Koutroubakis Department of Nuclear Medicine University Hospital of Heraklion Department of Gastroenterology University Hospital of Heraklion

The diagnosis of inflammatory bowel disease(IBD) depends on direct endoscopic visualization of the colonic and ileal mucosa and the histological study of the obtained *** and scintigraphic methods are mainly used as an adjunct to *** this review,we focus on the diagnostic potential of nuclear medicine *** value of all radiotracers is described with special reference to those with greater experience and more satisfactory ***-99m hexamethylpropylene amine oxime white blood cells remain a widely acceptable scintigraphic method for the diagnosis of IBD,as well as for the evaluation of disease extension and ***,pentavalent Tc-99m dimercaptosuccinic acid has been recommended as an accurate variant and a complementary technique to endoscopy for the follow-up and assessment of disease *** emission tomography alone or with computed tomography using fluorine-18 fluorodeoxyglucose appears to be a promising method of measuring inflammation in IBD patients.

关键词： Crohn's disease technetium-99m pentavalent dimercaptosuccinic acid Intestinal inflammation Scintigraphy Ulcerative colitis

Liposarcoma of the stomach: A rare case report

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World Journal of Gastroenterology 2007年第30期13卷 4154-4155页

作者： Konstantinos tepetes Gregory Christodoulidis Michael e Spyridakis maria Nakou George Koukoulis Konstantinos Hatzitheofilou General Surgery Department University Hospital of Larissa Larissa Greece Pathology Department University Hospital of Larissa Larissa Greece

Liposarcoma is the most common soft tissue sarcoma and accounts for 15%-20% of all mesenchymal malignancies. The tumor occurs most frequently in the limbs, retroperitoneum and rarely has a visceral location. We report a case of a gastric liposarcoma in a male patient. A 68 years old male patient was admitted to hospital for abdominal discomfort and fullness lasting for a month. He reported rare episodes of vomiting. The CT examination revealed a large epigastric mass （8 cm × 4 cm） involving the lesser curvature of the stomach, in contact with the pancreas and gallbladder. Fatty areas within the mass were evident. A total gastrectomy together with cholecystectomy was performed. The histopathological diagnosis was a well differentiated liposarcoma. The patient did not undergo any adjuvant treatment, he is under close follow up and two years later he is disease free. We report this case due to the rarity of this tumor in the stomach （nine cases reported in the literature）.

关键词： Gastric liposarcoma Lipoblasts CT diagnosis Total gastrectomy Well-differentiated type

Groups with Supersoluble Non-normal Subgroups

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Algebra Colloquium 2016年第2期23卷 213-218页

作者： maria De Falco maria Martusciello Carmela Musella Dipartimento di Matematica e Applicazioni Universita di Napoli Federico II Complesso Universitario Monte S. Angelo Via Cintia 1-80126 Napoli Italy

The structure of groups in which many subgroups have a certain property X has been investigated for several choices of the property χ.In particular, groups whose non-normal subgroups are supersoluble are studied ia t... 详细信息

关键词： supersoluble group polycyclic group normalizer subgroup

MIS 5e sea surface temperature estimation;a multi-proxy approach using a marine macrofossil assemblage(Mar Piccolo,Gulf of Taranto,Southern Italy)

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Journal of Palaeogeography 2024年第2期13卷 327-350页

作者： Pierluigi Santagati edoardo Perri maria Pia Bernasconi Mario Borrelli Salvatore Guerrieri Salvatore Critelli Dipartimento di Biologia Ecologia e Scienze della TerraUniversita della Calabriavia Pietro Bucci87036 Arcavacata di RendeCosenzaItaly Dipartimento di Ingegneria Ambientale Universita della Calabriavia Pietro Bucci87036 Arcavacata di RendeCosenzaItaly

It is reported a multi-proxy palaeoclimatic study conducted on a MIS 5e calcarenite from the Mar Piccolo Basin(MP),Gulf of Taranto(GT)(Central Mediterranean).The calcarenite returned a rich malacofauna consisting of 120 extant species,including four of the tropical Senegalese Fauna,today absent in the *** biogeographic-climatic affinity of the assemblage shows,compared to today,a double percentage of warm affinity species,while the cold affinity species are nearly equally represented,indicating a warmer but not strictly tropical *** is confirmed by the most recurring preferred SST ranges of the assemblage,indicating an average of 20℃.The skeletal compositions of five well-preserved molluscan and coral specimens were analyzed for trace elements and stable isotopes for further mean SST *** the comparison of the results of several equations available in literature,it appears that only some SST estimations are realistic,converging into similar values of,on average,20.8±0.9℃.Considering all the used proxies,the MIS 5e SST difference compared to today falls in the range 1.2—2.0℃for the GT(being a more reasonable scenario)and 2.0—2.8℃for the *** is not a firmly tropical-like SST setting as suggested by the sole Senegalese fauna,indicating at least 2.7℃—3.5℃more than today’s GT and MP,*** approximations and assumptions made for obtaining SST values with any single proxy indicate the need of a multi-proxy approach to define the best SST estimation.

关键词： MiS 5e Sea surface temperature Palaeoclimate proxy Fossil fauna Gulf of Taranto

Retrieving Multi-Scale Climatic Variations from High Dimensional Time-Series MODIS Green Vegetation Cover in a Tropical/Subtropical Mountainous Island

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Journal of Mountain Science 2014年第2期11卷 407-420页

作者： CHANG Chung-te WANG Hsueh-ching HUANG Cho-ying Department of Geography National Taiwan University

【Title】There are knowledge gaps in our understanding of vegetation responses to multi-scale climate-related variables in tropical/subtropical mountainous islands in the Asia-Pacific region. Therefore, this study investigated inter-annual vegetation dynamics and regular/irregular climate patterns in Taiwan. We applied principal component analysis （PCA） on 11 years （2001~2011） of high-dimensional monthly photosynthetically active vegetation cover （PV） derived from the Moderate Resolution Imaging Spectroradiometer （MODIS） and investigated the relationships between spatiotemporal patterns of the eigenvectors and loadings of each component through time and multi-scale climate-related variations. Results showed that the first five components contributed to 96.4% of the total variance. The first component （PC1, explaining 94.5% of variance） loadings, as expected, were significantly correlated with the temporal dynamics of the PV （r = 0.94）, which was mainly governed by regional climate. The temporal loadings of PC2 and PC3 （0.8% and 0.6% of variance, respectively） were significantly correlated with the temporal dynamics of the PV of forests （r = 0.72） and the farmlands （r = 0.80）, respectively. The low-order components （PC4 and PC5, 0.3% and 0.2% of variance, respectively） were closely related to the occurrence of drought （r = 0.49） and to irregular eNSO associated climate anomalies （r = -0.54）, respectively. Pronounced correlations were also observed between PC5 and the Southern Oscillation Index （SOI） with one to three months of time lags （r = -0.35 ~ -0.43, respectively）, revealing biophysical memory effects on the time-series pattern of the vegetation through eNSO-related rainfall patterns. Our findings reveal that the sensitivity of the ecosystems in this tropical/subtropical mountainous island may not only be regulated by regional climate and human activities but also be susceptible to large-scale climate anomalies which are crucial and comparable to previous large

关键词： Vegetation cover Vegetation dyn amics Principal component analysis(PCA) Regional climate Standardized precipitation index(SPI) Climatic anomaly e1 Nifio Southern Oscillation(eNSO)

A study on anti-fatigue effects in rats by nanoemulsion and liposome prepared from American ginseng root residue extract

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Food Bioscience 2022年第6期50卷 1509-1518页

作者： Chen-te Jen Bo-Yang Hsu Bing-Huei Chen Department of Food Science Fu Jen Catholic UniversityNew Taipei City24205Taiwan Department of Food and Beverage Management Lee-Ming Institute of TechnologyNew Taipei City243083Taiwan Department of Nutrition China Medical UniversityTaichung40402Taiwan

Ginseng root residue,a by-product obtained during ginseng beverage processing,was shown to contain a high amount of *** study aims to prepare nanoemulsion and liposome from American ginseng root residue extract(AGRe-Ne and AGRe-LP)for evaluation of anti-fatigue effects in *** AGRe-Ne was prepared by mixing an appropriate ratio of ginseng root residue extract,soybean oil,lecithin,Tween 80 and deionized water,while the AGRe-LP prepared by a suitable ratio of ginseng root residue,extract,Tween 80,phosphatidylcholine,cholesterol,PeG400 and deionized *** on dynamic light scattering and transmission electron microscopic methods,the mean particle size was 10.4 and 12.3 nm for AGRe-Ne respectively,while 53.5 and 61.2 nm for ***,both AGRe-Ne and AGRe-LP showed a high stability over a 90-day storage period at 4 and 25°C,but the former possessed a lower stability at 80 and 100°*** anti-fatigue experiment using a swimming rat model with caffeine as positive control demonstrated an extension of exhaustive swimming time and elevation of hepatic glycogen as well as a decline in both blood urea nitrogen and lactic acid levels,following administration with high and low doses of ginseng root residue extract,AGRe-Ne and *** comparison,both AGRe-Ne and AGRe-LP showed a pronounced anti-fatigue effect in rats,with a great potential to be developed into a functional food or even a botanic drug.

关键词： American ginseng Root residue Ginsenoside Nanoemulsion Liposome Anti-Fatigue Swimming rat model

effect of coordination restriction on pressure-induced fluorescence evolution

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Chinese Chemical Letters 2024年第12期35卷 589-593页

作者： Ziyou Zhang te Ji Hongliang Dong Zhiqiang Chen Zhi Su Jiangsu Collaborative Innovation Center of Biomedical Functional Materials College of Chemistry and Materials ScienceNanjing Normal University Center for High Pressure Science and technology Advanced Research Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of Sciences

The usage of flexible ligands in constructing MOF materials (FL-MOFs) has been widely studied due to its numerous advantages,including the structural diversity,polynuclear MOFs,transmitting magnetic exchanges,enantioselective separation,asymmetric catalysis,***,the field still faces challenges in deeply understanding the effect of ligand configuration on the properties of these ***,we employ a flexible aggregation-induced emission ligand (4,4-((1e,1 e)-anthracene-9,10-diylbis(ethene-2,1-diyl))dibenzoic acid) with great mechanical stability to construct FL-MOFs to lock the ligand configuration to explore the pressure-induced evolution of the ligand with coordination restriction,involving changes in fluorescence and intermolecular ***-situ high-pressure fluorescence,Raman,and FT-IR experiments have revealed that the intermolecular interaction of AIe-Mn-MOF with configuration restriction increased more rapidly than that of free *** discovery offers valuable insights for synthesizing MOF materials with exceptional mechanical stability and significantly advances our understanding of the impact of coordination restriction in FL-MOFs on their response to external stimuli.

关键词： Coordination chemistry High-pressure chemistry FL-MOFs High-pressure photoluminescent Coordination restriction

Is there a role for Tc-99m (V) DMSA scintigraphy in ischemic colitis?

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World Journal of Gastroenterology 2008年第35期14卷 5432-5435页

作者： maria I Stathaki Ioannis e Koutroubakis Sophia I Koukouraki elias A Kouroumalis Nikolaos S Karkavitsas Department of Nuclear Medicine University Hospital of HeraklionHeraklion 71110CreteGreece Department of Gastroenterology University Hospital of HeraklionHeraklion 71110CreteGreece

AIM: To evaluate the role of pentavalent Tc-99m dimercaptosuccinic acid [Tc-99m (V) DMSA] in the diagnosis of ischemic colitis. MeTHODS: Fourteen patients with endoscopically and histologically confirmed ischemic colitis were included in the study. Tc-99m (V) DMSA scintigraphy was performed within 2 d after colonoscopy. Images were considered positive when an area of increased activity was observed in the region of interest and negative when no abnormal tracer uptake was detected. ReSULTS: In 3 out of the 14 patients, Tc-99m (V) DMSA images showed moderate activity in the bowel. The scintigraphic results corresponded with the endoscopic findings. In the other 11 patients, no abnormal tracer uptake was detected in the abdomen. CONCLUSION: Besides the limited number of patients, Tc-99m (V) DMSA could not be considered as a useful imaging modality for the evaluation of ischemic colitis.

关键词： Scintigraphy technetium-99m pentavalentdimercaptosuccinic acid Ischemic colitis Intestinal ischemia Diagnosis

Catagenetic type of manganese ores:Ree and isotope(δ^(13)C,δ^(18)O)geochemical features(on the example of the Usa deposit,Russia)

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Acta Geochimica 2024年第6期43卷 1133-1152页

作者： Vladimir N.Kuleshov Andrey Yu.Bychkov Irina Yu.Nikolaeva maria e.Tarnopolskaia Geological Institute Russian Academy of SciencesPyzhevskii Per.7119017 MoscowRussia Lomonosov Moscow State University Leninskie Gory1119899 MoscowRussia

Chemical(Ree and major elements)and isotope(δ^(13)C,δ^(18)O)composition of carbonate manganese ores and manganese-bearing carbonates of the Usa deposit(Siberia,Russia)were *** data on the composition of Ree exhibit both the distinct negative(Ce/Ce*_(PAAS)e(Ce/Ce*_(PAAS)>1)cerium anomalies and the positive eu-anomaly(eu/eu*_(PAAS)>1).Negative eu-anomalies are not *** contents of Mn,Fe,Ree,and Ce-anomalies show a positive correlation with each ***-anomalies and the amount of manganese and Ree in relation to the carbon isotope composition(δ^(13)C)show a negative relationship and indicate that oxidized carbon of organic matter played an important role in the concentration of manganese and Ree in manganese *** chemical and isotope composition of examined rocks indicates on secondary formation of *** major phases and sources are distinguished in the ore-forming process characterized by diff erent chemical(Ree and ore elements)and isotope composition:(i)highgrade manganese ores(with high contents of Ree and light carbon isotope composition)and(ii)low-grade manganese ores(with low contents of Ree and heavy carbon isotope composition).

关键词： Manganese ore Ree Isotope composition Catagenesis Cambrian Siberia