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Prevalence of hypercoagulable states in stented thrombotic iliac vein compression syndrome with comparison of re-intervention and anticoagulation regimens

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World Journal of Radiology 2021年第12期13卷 371-379页

作者： Peyton Cramer Cheryl Mensah maria desancho Anuj Malhotra Ronald Winokur Andrew Kesselman Department of Radiology Division of Interventional RadiologyNew York Presbyterian Hospital/Weill Cornell MedicineNew YorkNY 10065United States Department of Medicine Division of Hematology-OncologyNew York Presbyterian Hospital/Weill Cornell MedicineNew YorkNY 10065United States Department of Radiology Division of Interventional RadiologyThomas Jefferson University HospitalPhiladelphiaPennsylvania 19107United States

BACKGROUND Endovascular therapy is playing an increasing role in the treatment of iliofemoral venous *** stent patency is multifactorial,and current management is based on best clinical practices,varying by *** To evaluate how thrombophilia influences management and outcomes of patients who undergo venous stenting for thrombotic iliac vein compression *** A retrospective observational analysis was performed on 65 patients with thrombotic iliac vein compression syndrome that underwent common iliac vein(CIV)stenting between December 2013 and December 2019 at a large academic *** criteria included CIV stenting and iliac vein *** lesions and iliocaval thrombosis and/or occlusions were excluded.A total of 65 patients were selected for final *** information,procedural data points,and post-procedural management and outcomes were *** analyses included Fisher's exact and Chi-square tests to compare discrete variables and the Wilcoxon rank-sum test to compare continuous variables between thrombophilia positive and negative *** 65 patients underwent successful balloon angioplasty and CIV *** these patients,33(50.8%)underwent thrombophilia testing,with 16(48.5%)testing *** patency on ultrasound did not significantly differ between thrombophilia positive and negative patients at 1 mo(92.3%vs 81.3%,P=0.6),6 mo(83.3%vs 80%,P>0.9),or 12 mo(77.8%vs 76.9%,P=0.8).Immediately after stent placement,thrombophilia patients were more likely to be placed on dual therapy(aspirin and anticoagulation)or triple therapy(aspirin,clopidogrel,and anticoagulation)(50%vs 41.2%,P>0.9),and remain on dual therapy at 6 mo(25%vs 12.5%,P=0.5)and 12 mo(25%vs 6.7%,P=0.6).There was no significant difference in re-intervention rates(25%vs 35.3%,P=0.7)or number of reinterventions(average 2.3 vs 1.3 per patient,P=0.4)between thrombophilia positive and negative ***

关键词： Thrombophilia Iliac vein compression syndrome Iliac vein stent May Thurner Anticoagulation Endovascular

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