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What is required for better progress in clinical and scientific andrology involving sperm assessments?

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Asian Journal of Andrology 2024年第3期26卷 229-232页

作者： Lars björndahl ANOVA Karolinska University Hospital and Karolinska Institutet Sweden Stockholm S-113 64

In scientific publications based on basicsemen examination,there is a generallack of consistency and transparencyregarding laboratory techniques *** support improvements in clinicaland scientific andrology,it is essential toincrease understanding of basic physiologyand biology,and enhance compliancewith existing recommendations andinternational *** designsneed to be improved as well as transparencyof laboratory methods used and openpublication of data obtained.

关键词： transparency consistency clinical

Takotsubo triggered by acute myocardial infarction：a common but overlooked syndrome？

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Journal of Geriatric Cardiology 2014年第2期11卷 171-173页

作者： bj orn Redfors Wallenberg Laboratory Department of Molecular and Clinical Medicine Sahlgrenska Academy at University of Gothenburg Bruna Straket 16 413 45 Go-thenburg Sweden Department of Cardiology Sahlgrenska University Hospital Bruna Straket 16 413 45 Gothenburg Sweden

Takotsubo cardiomyopathy （TCM） is an acute cardiac syndrome characterized by extensive, but potentially reversible, left ventricular dysfunction in the absence of an explanatory coronary obstruction. Thus, TCM is distinct from coronary artery disease （CAD） and acute myocardial infarction （AMI）. However, substantial evidence for co-existing CAD in some TCM patients exist. Herein, we take this associa-tion one step further and present a case in which the patient simultaneously suffered from AMI and TCM, and in which we believe that a primary coronary event triggered TCM. An 88-year-old female presented with chest pain. Echocardiography revealed apical akinesia with hypercontractile bases. An occluded diagonal branch with suspected acute plaque rupture was identified on the angiogram, but could not explain the extent of akinesia. Cardiac function recovered completely. Thus, this patient adhered to current diagnostic criteria for TCM. TCM is a well-known complication for other conditions associated with somatic stress. It is therefore intuitive to assume that AMI, which also associates with somatic stress and elevated catecholamine, can cause TCM. Our case illustrates that TCM and AMI may occur simulta-neously. Although causality cannot be conclusively inferred from this association, the somatic stress associated with AMI may have caused TCM in this patient.

关键词： Acute myocardial infaction Catecholamine Coronary artery disease Somatic stress Takotsubo cardiomyopathy

Influence of amphiphilic structures on the stability of polyphenols with different hydrophobicity

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Science China Chemistry 2007年第1期50卷 121-126页

作者： Bergensthl bjRN Food Technology Center for Chemistry and Chemical EngineeringLund UniversityPO Box 124S-22100LundSweden

Autooxidation of five polyphenols representing range of different hydrophobicities(catechin gallate (CG),(-)catechin((-)C),epicatechin(EC),epigallocatechin gallate(EGCG)and epigallocatechin(EGC)) in three different aqueous solutions:molecular solution,micellar solution(Tween-20)and liposomal dispersion(soybean lecithin)was monitored by *** rate of oxidation of the five polyphenols was higher at pH 4.5 than at pH *** with the control,addition of Tween-20(micellar structure)and lecithin(liposomal structure)significantly decreased the degradation of *** the presence of lecithin the autooxidation of all the five polyphenols was slower than in the presence of Tween-20. The effective protection of the colloidal structures was compared with the hydrophobicity of the poly- phenols estimated from the partitioning between octanol and *** protection from oxidation in the presence of the colloidal structures(micellar or liposomal)increased with increasing partitioning of a polyphenol towards the hydrophobic *** protecting effect of the colloidal structures was more effective at pH 4.5 than at pH 3.5.

关键词： amphiphilic structures autooxidation polyphenols K value effective protection

Nohab F系列柴油机在近海作业中的应用

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柴油机 1987年第4期 22-28页

作者： Tommy bjrkqvist 汤益明

本文讨论了近海作业市场对发动机的各种要求,介绍了各种不同的近海作业应用情况,并讨论了发展趋势和代用燃料等问题。为了适应现在和将来近海作业中的种种需求,本文叙述了一个柴油机系列的研制过程,讨论了发动机和装置系统。还对应用情... 详细信息

本文讨论了近海作业市场对发动机的各种要求,介绍了各种不同的近海作业应用情况,并讨论了发展趋势和代用燃料等问题。为了适应现在和将来近海作业中的种种需求,本文叙述了一个柴油机系列的研制过程,讨论了发动机和装置系统。还对应用情况和技术服务的经验作了评述。

关键词：近海作业供应船装置冷却系统供应舰民用船散热系统热力系统柴油机厂发动机 Nohab F

Solanaceae pangenomes are coming of graphical age to bring heritability back

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aBIOTECH 2022年第4期3卷 233-236页

作者： björn Usadel Institute for Biological Data Science CEPLASHeinrich Heine UniversityDüsseldorfGermany IBG-4 Bioinformatics BioSCForschungszentrum JülichJülichGermany

Two recent articles describe a pangenome of potato and a graph-based pangenome for tomato,*** latter improves our understanding of the tomato genomics architecture even further and the use of this graph-based pangenom... 详细信息

关键词： Tomato Potato Pangenome Graph-based pangenome Heritability

Diagnosis and treatment of pancreatic exocrine insufficiency

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World Journal of Gastroenterology 2013年第42期19卷 7258-7266页

作者： bjrn Lindkvist Institute of Medicine Sahlgrenska AcademyUniversity of GothenburgSE-413 45 GothenburgSweden Division of Gastroenterology and Hepatology Department of Internal MedicineSahlgrenska University HospitalSE-413 45 GothenburgSweden

Pancreatic exocrine insufficiency is an important cause of maldigestion and a major complication in chronic *** digestion requires adequate stimulation of pancreatic secretion,sufficient production of digestive enzymes by pancreatic acinar cells,a pancreatic duct system without significant outflow obstruction and adequate mixing of the pancreatic juice with ingested *** in any of these steps may result in pancreatic exocrine insufficiency,which leads to steatorrhea,weight loss and malnutrition-related complications,such as *** evaluating digestion,such as fecal fat quantification and the13C-mixed triglycerides test,are the most accurate tests for pancreatic exocrine insufficiency,but the probability of the diagnosis can also be estimated based on symptoms,signs of malnutrition in blood tests,fecal elastase 1 levels and signs of morphologically severe chronic pancreatitis on *** for pancreatic exocrine insufficiency includes support to stop smoking and alcohol consumption,dietary consultation,enzyme replacement therapy and a structured follow-up of nutritional status and the effect of *** enzyme replacement therapy is administered in the form of enteric-coated minimicro-spheres during *** dose should be in proportion to the fat content of the meal,usually 40-50000 lipase units per main meal,and half the dose is required for a *** cases that do not respond to initial treatment,the doses can be doubled,and proton inhibitors can be added to the *** review focuses on current concepts of the diagnosis and treatment of pancreatic exocrine insufficiency.

关键词： Chronic pancreatitis Pancreatic exocrine insufficiency Pancreatic enzyme replacement therapy

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WN25系列柴油机的可靠性

国外内燃机车 1991年第7期 20-25页

作者： T.bjrkqvist 王世杰

WN25系列柴油机1962年开始生产,它的应用范围主要包括:船用发动机;海上半潜平台的辅助和备用动力装置;核动力电站的应急发电装置;固定式基底负载发电机组等。该柴油机多年来在各种不同工况下运用,均验证具有高度的可靠性。本文将讨论如... 详细信息

WN25系列柴油机1962年开始生产,它的应用范围主要包括:船用发动机;海上半潜平台的辅助和备用动力装置;核动力电站的应急发电装置;固定式基底负载发电机组等。该柴油机多年来在各种不同工况下运用,均验证具有高度的可靠性。本文将讨论如下各项对可靠性的影响:发展的连续性;组件的应用;质量保证体系的建立;预维修。重点分析了对某些重要部件可靠性产生影响的一种分析方法。

关键词：可靠性柴油机内燃机车

ULK1 as a novel therapeutic target in neurodegeneration

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Neural Regeneration Research 2021年第6期16卷 1212-1213页

作者： björn Friedhelm Vahsen Paul Lingor Nuffield Department of Clinical Neurosciences University of OxfordJohn Radcliffe HospitalOxfordUK Department of Neurology University Medical Center GöttingenGöttingenGermany Center for Biostructural Imaging of Neurodegeneration(BIN) DFG Cluster of Excellence Nanoscale Microscopy and Molecular Physiology of the Brain(CNMPB)University Medical Center GöttingenGöttingen Department of Neurology Rechts der Isar Hospital of the Technical University MunichMunichGermany

Axonal degeneration is an early and key pathophysiological feature of many traumatic and neurodegenerative disorders of the central nervous system(CNS),such as spinal cord injury(SCI),Parkinson’s disease(PD),and amyotrophic lateral sclerosis(ALS).As the regenerative capacity of injured axons is severely restricted in the CNS,axonal degeneration frequently results in the irreversible loss of neuronal connections causing progressive neurological deficits and clinical disability.A better understanding of the mechanisms of axon degeneration is therefore hoped to unravel new therapeutic avenues to combat neurodegeneration(Lingor et al.,2012).

关键词： degeneration therapeutic neurodegeneration

Is a catalyst always beneficial in plasma catalysis? Insights from the many physical and chemical interactions

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Journal of Energy Chemistry 2023年第10期85卷 501-533,I0013页

作者： björn Loenders Roel Michiels Annemie Bogaerts Research group PLASMANT Department of ChemistryUniversity of AntwerpUniversiteitsplein 1B-2610 Wilrijk-AntwerpBelgium

Plasma-catalytic dry reforming of CH_(4)(DRM) is promising to convert the greenhouse gasses CH_(4) and CO_(2) into value-added chemicals, thus simultaneously providing an alternative to fossil resources as feedstock for the chemical industry. However, while many experiments have been dedicated to plasma-catalytic DRM, there is no consensus yet in literature on the optimal choice of catalyst for targeted products,because the underlying mechanisms are far from understood. Indeed, plasma catalysis is very complex,as it encompasses various chemical and physical interactions between plasma and catalyst, which depend on many parameters. This complexity hampers the comparison of experimental results from different studies, which, in our opinion, is an important bottleneck in the further development of this promising research field. Hence, in this perspective paper, we describe the important physical and chemical effects that should be accounted for when designing plasma-catalytic experiments in general, high-lighting the need for standardized experimental setups, as well as careful documentation of packing properties and reaction conditions, to further advance this research field. On the other hand, many parameters also create many windows of opportunity for further optimizing plasma-catalytic ***, various experiments also reveal the lack of improvement in plasma catalysis compared to plasma-only, specifically for DRM, but the underlying mechanisms are unclear. Therefore, we present our newly developed coupled plasma-surface kinetics model for DRM, to provide more insight in the underlying reasons. Our model illustrates that transition metal catalysts can adversely affect plasmacatalytic DRM, if radicals dominate the plasma-catalyst interactions. Thus, we demonstrate that a good understanding of the plasma-catalyst interactions is crucial to avoiding conditions at which these interactions negatively affect the results, and we provide some recommendations for im

关键词： Plasma catalysis Dry reforming of methane Discharges Reaction kinetics Modelling