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Patency and agile capsules

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World Journal of Gastroenterology 2008年第34期14卷 5269-5273页

作者： ngel Caunedo-lvarez Javier romero-Vazquez Juan M Herrerias-Gutierrez Gastroenterology Service "Virgen Macarena" University Hospital

Small bowel strictures can be missed by current diagnostic methods. The Patency capsule is a new non-endoscopic dissolvable capsule which has as an objective of checking the patency of digestive tract, in a non-invasive manner. The available clinical trials have demonstrated that the Patency capsule is a good tool for assessment of the functional patency of the small bowel, and it allows identification of those patients who can safely undergo a capsule endoscopy, despite clinical and radiographic evidence of small-bowel obstruction. Some cases of intestinal occlusion have been reported with the Patency capsule, four of them needed surgery. So, a new capsule with two timer plugs (Agile capsule) has been recently developed in order to minimize the risk of occlusion. This new device stars its dissolution process earlier (30 h after ingestion) and its two timer plugs have been designed to begin the disintegration even when the device is blocked in a tight stricture.

关键词： Capsule endoscopy Patency capsule Agile capsule Small bowel strictures

Bioengineering models of female reproduction

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Bio-Design and Manufacturing 2020年第3期3卷 237-251页

作者： maria EZubizarreta Shuo Xiao Department of Environmental Health Sciences Arnold School of Public HealthUniversity of South CarolinaColumbiaSC 29208USA Department of Pharmacology and Toxicology Ernest Mario School of PharmacyEnvironmental Health Sciences InstituteRutgers University170 Frelinghuysen RoadPiscatawayNJ 08854USA

The female reproductive system consists of the ovaries,the female gonads,and the reproductive tract organs of the fallopian tubes,uterus,cervix,and *** functions to provide hormonal support and anatomical structure for the production of new offspring.A number of endogenous and exogenous factors can impact female reproductive health and fertility,including genetic vulnerability,medications,environmental exposures,age,nutrition,and *** date,due to the ethical concerns of using human subjects in biomedical research,the majority of studies use in vivo animal models and 2D cell/tissue culture models to study female ***,the complexity and species difference of the female reproductive system in humans make it difficult to compare to those of ***,the monolayered cells cultured on flat plastics or glass lose their 3D architecture as well as the physical and/or biochemical contacts with other cells in ***,all reproductive organs do not work alone but interconnect with each other and also with non-reproductive organs to support female reproductive,endocrine,and systemic *** facts suggest that there is an urgent and unmet need to develop representative,effective,and efficient in vitro models for studying human female *** prodigious advancements of bioengineering(e.g.,biomaterials,3D printing,and organ-on-a-chip)allow us to study female reproduction in an entirely new ***,we review recent advances that use bioengineering methods to study female reproduction,including the bioengineering models of the ovary,fallopian tube,uterus,embryo implantation,placenta,and reproductive disease.

关键词： Female reproduction Bioengineering Biomaterials 3D printing Microfluidics

Entry of hepatitis C virus into the cell: A therapeutic target

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World Journal of Gastroenterology 2012年第33期18卷 4481-4485页

作者： José Antonio Del Campo ngela Rojas Manuel romero-Gómez Unit for Medical and Surgical Management of Digestive Diseases Center for Biomedical Research in Digestive and Liver Diseases Network (CIBERehd) Valme University Hospital University of Seville E-41014 Sevilla Spain

Several receptors have been identified as implicated on viral entry into the hepatocyte; and, this interaction between the virus and potential receptors could modulate infection, spontaneous viral clearance, persistence of the infection and the widespread of the virus as outbreak. Nevertheless, the playing role of each of them remains controversial. The NiemannPick type C1 like 1 gene (NPC1L1) receptor has been recently implicated on hepatitis C virus (HCV) entry into the cell and ezetimibe, an anti-cholesterol drug seems to block that, emerging the idea to control hepatitis C outbreak modulating lipid-related receptors. Hepatitis C infection seems to modulate lipid metabolism according to host genetic background. Indeed, it circulates like a lipoviroparticle. The main aim of this field of vision would be to discuss the role of hepatocyte receptors implicated on virus entry, especially NPC1L1 and the therapeutic options derived from the better knowledge about HCV-lipidsreceptors interaction.

关键词： Hepatitis C virus entry Niemann-Pick type C1 like 1 gene Lipid metabolism Ezetimibe

Landform Instability and Land-use Dynamics in Tropical High Mountains, Central Mexico

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Journal of Mountain Science 2012年第3期9卷 414-430页

作者： GARCíA-romero Arturo ACEVES-QUESADA José Fernando ARREDONDO-LEóN Carlos Departamento de Geografía Física Instituto de Geografía Universidad Nacional Autónoma de México. Circuito exterior s/n Ciudad Universitaria 04510 Mexico Distrito Federal Mexico Unidad Académica de Estudios Regionales de la Coordinación de Humanidades Universidad Nacional Autónoma de México

This investigation is an analysis of the influence of landform instability on the distribution of land-use dynamics in a hydrographical basin, located in the Mexican Volcanic Belt mountain range (central Mexico), currently affected by substantial changes in land use and deforestation. A landform map was produced, in addition to seven attribute maps - altimetry, drainage density, slope, relief energy, potential erosion, geology and tectonics - which were considered as factors for determining landform instability through Multi-criteria Evaluation Analysis. Likewise, the direction and rhythm of land-use dynamics were analyzed in four dates - between 1976 and 2000 - and cross tabulations were made between them, in order to analyze the trends and processes of land-use dynamics. Afterwards, the databases obtained were cross tabulated with the landform variables to derive areas, percentages and correlation indices. In the study area, high-instability landforms are associated with most ancient volcanic and sedimentary landforms, where high altitude, drainage density, slope and potential to develop gravitational and fluvial processes are the major factors favouring a land-use pattern, dominated by the conservation of extensive forest land, abandonment of human land use and regeneration of disturbed areas. In contrast, low-instability landforms correspond to alluvial plains and lava hills covered by pyroclasts, where low potential erosion to develop fluvial processes, added to water and soil availability and accessibility, have favoured a land-use pattern dominated by the expansion of agroforestry plantations and human settlements, showing a marked trend towards either intensification or permanence of the current land use and with little abandonment and regeneration.

关键词： Landform instability Multi-criteriaEvaluation Analysis Land-use change and processes Tuxpan River Basin

A question on partial CAP-subgroups of finite groups

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Science China Mathematics 2012年第5期55卷 961-966页

作者： BALLESTER-BOLINCHES Adolfo ESTEBAN-romero Ramón LI YangMing Departament d'Àlgebra Universitat de ValènciaBurjassot 46100ValènciaSpain Institut Universitari de Matemàtica Pura i Aplicada Universitat Politècnica de ValènciaValència 46022Spain Department of Mathematics Guangdong University of EducationGuangzhou 510310China

A subgroup H of a finite group G is a partial CAP-subgroup of G if there is a chief series of G such that H either covers or avoids every chief factor of the *** structural impact of the partial cover and avoidance property of some distinguished subgroups of a group has been studied by many ***,there are still some open questions which deserve an *** purpose of the present paper is to give a complete answer to one of these questions.

关键词： finite groups minimal subgroups partial cover and avoidance property saturated formations

Environmental Factors that Affect Primary Plant Succession Trajectories on Lahars(Popocatépetl Volcano,Mexico)

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Journal of Mountain Science 2015年第5期12卷 1254-1266页

作者： GARCIA-romero Arturo ALANIS-ANAYA Rocío Marisol MUNOZ-JIMENEZ Julio Departamento de Geografía Física Instituto de GeografíaUniversidad Nacional Autónoma de México.Circuitoexterior s/nCiudad Universitaria04510 MexicoDistrito FederalMexico Laboratorio de Análisis Geoespacial Instituto de GeografíaUniversidad Nacional Autónoma de México.Circuitoexterior s/nCiudad Universitaria04510 MexicoDistrito FederalMexico Departamento de A.G.R.y Geografía Física Facultad de Geografía e HistoriaUniversidad Complutense de Madrid.Calle Profesor Aranguren s/nCiudad Universitaria28040MadridSpain

The earliest stages of plant succession on severely disturbed sites usually follow highly unpredictable trajectories. However, in the Popocatépetl volcano area(50 km SE of Mexico City),the development of physiognomically distinct primary plant communities suggests the occurrence of various successional trajectories only 10 years after the onset of colonization of a temperate forest on lahars. To characterize plant communities and determine the environmental factors that drive the differences observed between plant communities and their successional trajectories, we monitored 64 circular sample plots(3.14 m2) from 2002 to 2011. We examined the plant communities' composition and structure in terms of their species richness and abundance, plant cover, and maximum stem height,and recorded 13 environmental factors related to the volcanic deposit characteristics, microclimate, soil,flow dynamics and gravitational processes. A cluster analysis of the species abundance data showed that,by 2011, six plant community types(CT's) had established, including grasslands, and open, dense and very dense shrub lands. As these communities developed over the same period of time and within the same overall ecosystem, then these plant community types were interpreted as different stages of the same successional trajectory. Two sequential main stages that drive regeneration were identified from this successional trajectory: a) the first four years are characterized by a steady increase in species richness and physiognomic development(plant size and coverage), mostly dominated by Baccharis conferta, Eupatorium glabratum and Senecio barbajohannis; b) from the sixth year onwards, a continued increase in the abundance of those same species led to the development of the dense shrubland *** in the availability of soil resources and disturbances linked to recent lahar flows were the main factors accounting for such differences.

关键词： Ecosystem regeneration Plantcolonization Primary succession Temperate forest Light exposure Elevation Soil Slope aspect

Simultaneous penile prosthesis and male sling/artificia urinary sphincter

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Asian Journal of Andrology 2013年第1期15卷 10-15页

作者： Dominic Lee Claudio romero Frances Alba O Lenaine Westney Run Wang Department of Urology University of Texas MD Anderson Cancer Center Houston TX 77030 USA and Division of Urology University of Texas Medical School at Houston Houston TX 77030 USA

Erectile dysfunction （ED） and stress urinary incontinence （SUI） from urethral sphincteric deficiency is not an uncommon problem. The commonest etiology is intervention for localized prostate cancer and/or radical cystoprostatectomy for muscle invasive bladder cancer. Despite advances in surgical technology with robotic assisted laparoscopic prostatectomy and nerve sparing techniques, the rates of ED and SUI remain relatively unchanged. They both impact greatly on quality of life domains and have been associated with poor performance outcomes. Both the artificial urinary sphincter and penile prosthesis are gold standard treatments with proven efficacy, satisfaction and durability for end-stage SUI and ED respectively. Simultaneous prosthesis implantation for concurrent conditions has been well described, mostly in small retrospective series. The uptake of combination surgery has been slow due in part to technical demands of the surgery and to an extent, a heightened anxiety over potential complications. This paper aims to discuss the technical aspect of concurrent surgery for both disease entity and the current published outcomes of the various surgical techniques with this approach.

关键词： artificial urinary sphincter dual implants erectile dysfunction penile prosthesis stress urinary incontinence

Hyperparameter optimization of YOLOv8 for smoke and wildfire detection:Implications for agricultural and environmental safety

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Artificial Intelligence in Agriculture 2024年第2期12卷 109-126页

作者： Leo Ramos Edmundo Casas Eduardo Bendek Cristian romero Francklin Rivas-Echeverría Kauel Inc. Menlo Park(Silicon Valley)CA 94025USA Computer Vision Center Universitat Autònoma de BarcelonaBellaterra 08193Spain Faculty of Engineering University of DeustoBilbao 48007Spain Jet Propulsion Laboratory NASAPasadenaCA 91109USA

In this study,we extensively evaluated the viability of the state-of-the-art YOLOv8 architecture for object detec-tion tasks,specifically tailored for smoke and wildfire identification with a focus on agricultural and environmen-tal *** available versions of YOLOv8 were initially fine-tuned on a domain-specific dataset that included a variety of scenarios,crucial for comprehensive agricultural ***‘large’version(YOLOv8l)was se-lected for further hyperparameter tuning based on its performance *** model underwent a detailed hyperparameter optimization using the One Factor At a Time(OFAT)methodology,concentrating on key param-eters such as learning rate,batch size,weight decay,epochs,and *** from the OFAT study were used to define search spaces for a subsequent Random Search(RS).The final model derived from RS demon-strated significant improvements over the initial fine-tuned model,increasing overall precision by 1.39%,recall by 1.48%,F1-score by 1.44%,mAP@0.50 by 0.70%,and mAP@0.50:0.95 by 5.09%.We validated the enhanced model's efficacy on a diverse set of real-world images,reflecting various agricultural settings,to confirm its ro-bustness in detecting smoke and *** results underscore the model's reliability and effectiveness in scenar-ios critical to agricultural safety and environmental *** work,representing a significant advancement in the field of fire and smoke detection through machine learning,lays a strong foundation for fu-ture research and solutions aimed at safeguarding agricultural areas and natural environments.

关键词： Agricultural safety Wildfire detection Smoke detection Object detection Computer vision YOL

Nanosized magnetite in low cost materials for remediation of water polluted with toxic metals, azo- and antraquinonic dyes

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Frontiers of Environmental Science & Engineering 2015年第5期9卷 746-769页

作者： maria Fernanda HORST Veronica LASSALLE maria Lujan FERREIRA Institute of Chemistry of the South (Inquisur Universidad Nacional del Sur~ONICET) Avda Alem 1253 Bahia Blanca Argentina Pilot Plant of Chemical Engineering (PLAPIQUI-UNS-CONICET) Universidad Nacional del Sur--CONICET Camino La Carrindanga km7 Bahia Blanca Argentina

Nanosized magnetite has emerged as an adsorbent of pollutants in water remediation. Nanoadsor- bents include magnetic iron oxide and its modifiers/ stabilizers, such as carbon, silica, clay, organic moieties （polymers, aminoaeids, and fatty acids） and other inorganic oxides. This review is focused on the recent developments on the synthesis and use of magnetic nanoparticles and nanocomposites in the treatment of contaminated water. The emphasis is on the influence of the iron oxide modifiers on some properties of interest such as size, BET area, and magnetization. The characteristics of these nanomaterials are related to their ability to eliminate heavy metal ions and dyes from wastewater. Comparative analysis of the actual literature was performed aiming to present the magnetic material, its preparation methodology and performance in the elimination of the selected pollutants. Vast information has been properly summarized according to the materials, their properties and preferential affinity for selected contaminants. The mechanisms governing nanomaterial＇s formation as well as the interactions with heavy metals and dyes have been carefully analyzed and associated to their efficiency.

关键词： nanomagnetite water remediation toxicmetals dyes supported magnetite