检索结果-南通市图书馆

World Journal of Gastroenterology 2009年第27期15卷 3341-3348页

作者： Fabio Baldi maria antonia bianco Gerardo Nardone Alberto Pilotto Emanuela Zamparo Gastroenterology Unit S. Orsola-Malpighi HospitalVia Massarenti 9 40138 Bologna Italy

Diarrhoea is an alteration of normal bowel movement characterized by an increase in the water content, volume, or frequency of stools. Diarrhoea needs to be classified according to the trends over time （acute or chronic） and to the characteristics of the stools （watery, fatty, inflammatory）. Secretory diarrhoeas, mostly acute and of viral aetiology in more than 70% of cases, are by far the most important subtype of diarrhoeas in terms of frequency, incidence and mortality （over 2.5 million deaths/year in developing countries）. Natural and synthetic opiates such as morphine, codeine, and Ioperamide which react with endogenous opiates （enkephalins, beta-endorphins, dynorphins） mainly act on intestinal motility and slow down transit. An antidiarrhoeal drug developed in recent years, racecadotril, acts as an enkephalinase inhibitor. Clinical studies have shown that it is just as effective as ioperamide in resolving acute diarrhoea but with greater reduction in pain and abdominal distension. Some studies have explored the prevalence of diarrhoea in old age. An epidemiological study carried out in Italy by 133 General Practitioners on 5515 elderly outpatients reported a prevalence of diarrhoea, defined according to the Rome criteria, of 9.1%. Infectious diseases （19%） and drug use （16%） were the most common causes of diarrhoea in old age. Regardless of the cause, the treatment of elderly patients with diarrhoea must include rehydration and nutritional support. Every year, more than 50 million tourists travel from industrialized countries to places where hygiene levels are pool. At least 75% of those travelling for short periods mention health problems, and in particular traveller＇s diarrhoea.

关键词： Diarrhoea Secretory diarrhoeas Elderly patients Traveller's diarrhoea Antidiarrhoeal drugs Enkephalinase inhibitor Racecadotril Efficacy Tolerability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Localized amyloidosis of the stomach:A case report

引用

World Journal of Gastroenterology 2007年第12期13卷 1877-1878页

作者： Gianluca Rotondano Raffaele Salerno Fabio Cipolletta maria antonia bianco Antonino De Gregorio Raffaele Miele Antonio Prisco maria Lucia Garofano Livio Cipolletta Division of Gastroenterology Hospital Maresca Torre del Greco Italy University of Naples School of Medicine Department of Gastroenterology Naples Italy Division of Pathology Hospital Maresca Torre del Greco Italy

We report an unusual case of primary amyloidosis of the stomach in a patient complaining of dyspeptic symptoms. The diagnosis was confirmed histologically and other gastrointestinal site or systemic involvement was ru... 详细信息

关键词： Amyloidosis Gastrointestinal tract Dyspepsia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Complementary roles of glial cells in generating region-specific neuroinflammatory responses and phagocytosis in Parkinson’s disease

引用

Neural Regeneration Research 2025年第10期20卷 2917-2918页

作者： Leyre Ayerra maria S.Aymerich Universidad de Navarra Facultad de CienciasDepartamento de Bioquímica y GenéticaPamplonaSpain CIMA-Universidad de Navarra PamplonaSpain IdiSNA Instituto de Investigación Sanitaria de NavarraPamplonaSpain

Neuroinflammation is associated with Parkinson’s disease:Reactive gliosis and neuroinflammation are hallmarks of Parkinson’s disease(PD),a multisystem neurodegenerative disorder characterized by a progressive loss of dopaminergic *** has long been considered a mere consequence of neuronal loss,but whether it promotes PD or is a key player in disease progression remains to be *** leukocyte antigen.

关键词： inflammation leukocyte generating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Calcium-sensitive protein MLC1 as a possible modulator of the astrocyte functional state

引用

Neural Regeneration Research 2025年第7期20卷 2008-2010页

作者： Elena Ambrosini Angela Lanciotti maria Stefania Brignone Department of Neuroscience Istituto Superiore di SanitàRomeItaly

Astrocytes,the main population of glial cells in the central nervous system(CNS),exert essential tasks for the control of brain tissue homeostasis,supporting neuron and other glial cell activity from the developmental stage to adult *** maintain the optimal functionality of the brain,astroglial cells are particularly committed to reacting to every change in tissue homeostatic conditions,from mild modifications of the physiological environment,a process called astrocyte activation,to the more severe alterations occurring in pathological situations causing astrocyte reactivity or reactive astrogliosis(Escartin et al.,2021).During these reactive states,astrocytes mount an active,progressive response encompassing morphological,molecular,and interactional remodeling,leading to the acquisition of new functions and the loss of others,whose intensity,duration,and reversibility are dependent on the nature of the stimulus and regulated in a context-specific manner.

关键词： alterations modulator maintain

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Identification and Cloning of Differentially Expressed Genes Involved in the Interaction Between Potato and Phytophthora infestans using a Subtractive Hybridization and cDNA-AFLP Combinational Approach

引用

Journal of Integrative Plant Biology 2010年第5期52卷 453-467页

作者： maria antonia Henriquez Fouad Daayf Department of Plant Science University of Manitoba222 Agriculture BuildingWinnipeg R3T2N2Canada

Using a subtractive hybridization （SH）/cDNA-AFLP combinational approach, differentially expressed genes involved in the potato-Phytophthora infestans interaction were identified. These included genes potentially controlling pathogenesis or avr genes in P. infestans as well as those potentially involved in potato resistance or susceptibility to this pathogen. Forty-one differentially expressed transcript, derived fragments （TDFs）, resulting from the interaction, were cloned and sequenced. Two TDFs, suggested as potential pathogenicity factors, have sequence similarity to N-succinyl diaminopimelate aminotransferase and a transcriptional regulator, TetR family gene, respectively. Two other TDFs, suggested as potential avr genes, have sequence similarity to an EST sequence from Avr41Cf.41Avr91Cf- 9 and a P. infestans avirulence-associated gene, respectively. Genes＇ expression and origin were confirmed using Southern blots, Northern blots and qRT-PCR, he., potential resistance gene DL81 was induced at 12 hpi in the moderately resistant cultivar, whereas it was down-regulated as early as 6 hpi in the susceptible cultivar. On the other hand, DL21 was induced at 6 hpi （3.38-fold） in response to the highly aggressive isolate （US8） and strongly up-regulated thereafter （25.13-fold at 120 hpi.）, whereas it was only slightly up-regulated in response to the weakly aggressive isolate US11 （3.82-fold at 96 hpi）, suggesting its potential involvement as a susceptibility gene.

关键词： cDNA SH AFLP Identification and Cloning of Differentially Expressed Genes Involved in the Interaction Between Potato and Phytophthora infestans using a Subtractive Hybridization and cDNA-AFLP Combinational Approach

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multi-frame and multi-dimensional historical digital cities: the Como example

引用

International Journal of Digital Earth 2014年第4期7卷 336-350页

作者： Luana Valentini maria antonia Brovelli Giorgio Zamboni Politecnico di Milano-Polo di Como DIIARComoItaly

In this article,we present the realisation of a multi-frame and multi-dimensional WebGIS that allows users to simultaneously analyse a specific portion of the Earth taking into account the historical information,*** graphical panels have been realised:one for the usual 2D view and one for a more realistic 3D *** panels display historical maps of the city,the current orthophoto and the digital topographical *** 3D frame is based on NASA World Wind,an open source virtual globe from where 3D buildings are shown extruding the 2D shapes using their mean *** to a specifically designed graphical user interface,it is also possible to dynamically thematise the buildings on the globe according to different criteria(*** construction time span)so that only the geometries fulfilling the request are turned *** the proposed application,a synchronisation between the two panels has been implemented,in order to maintain a constant alignment of the two *** application is also open to the time *** fact,assigning to each geometry two dates(e.g.‘year of construction’and‘year of demolition’),it is possible to dynamically view how buildings have changed over time,both in their shape and *** developments of this work will concern the possibility of implementing a city model with a higher level of detail.

关键词： web application multi-frame multi-dimensional time historical maps 3D

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Public Participation GIS:a FOSS architecture enabling field-data collection

引用

International Journal of Digital Earth 2015年第5期8卷 345-363页

作者： maria antonia Brovelli Marco Minghini Giorgio Zamboni DICA Politecnico di MilanoComoItaly

Driven by the rise of Web 2.0 and the non-stop spread of mobile device sensors,the concept of Public Participation GIS(PPGIS)is knowing a revolutionary era which perfectly fits the new vision of Digital Earth(DE).This research investigates the opportunity to build up a PPGIS prototype with completely Free and Open Source Software(FOSS)architecture,in which data directly come from field surveys carried out by users.A sample application related to urban monitoring is addressed,which concentrates on user field-collected data concerning reports of road pavement *** Data Kit suite allows users to collect geotagged multimedia information using mobile devices with onboard location sensors(e.g.a Global Positioning System receiver).On field-captured data are sent to a server and stored into a PostgreSQL database with PostGIS spatial *** then disseminates data on the *** the client-side,different solutions allow data visualization on both desktop computers and mobile *** designed architecture provided support for FOSS usage in the process of gathering,uploading,and Web publishing information collected in *** implementation of the developed PPGIS could thus substantially increase public active participation in data creation and sharing,besides enlarging DE knowledge up to the local level.

关键词： GeoWeb FOSS mobile PPGIS Web Mapping

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

High-resolution land cover classification:cost-effective approach for extraction of reliable training data from existing land cover datasets

引用

International Journal of Digital Earth 2023年第1期16卷 3618-3636页

作者： Gorica Bratic Vasil Yordanov maria antonia Brovelli Politecnico di Milano MilanItaly

There has been a significant increase in the availability of global high-resolution land cover(HRLC)datasets due to growing demand and favorable technological ***,this has brought forth the challenge of collecting reference data with a high level of detail for global *** photo-interpretation is considered optimal for collecting quality training data for global HRLC mapping,some producers of existing HRLCs use less trustworthy sources,such as existing land cover at a lower resolution,to reduce *** work proposes a methodology to extract the most accurate parts of existing HRLCs in response to the challenge of providing reliable reference data at a low *** methodology combines existing HRLCs by intersection,and the output represents a Map Of Land Cover Agreement(MOLCA)that can be utilized for selecting training ***’s effectiveness was demonstrated through HRLC map production in Africa,in which it generated 48,000 *** best classification test had an overall accuracy of 78%.This level of accuracy is comparable to or better than the accuracy of existing HRLCs obtained from more expensive sources of training data,such as photo-interpretation,highlighting the cost-effectiveness and reliability potential of the developed methodology in supporting global HRLC production.

关键词： High-resolution land cover global land cover training data reference data data quality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A cup of coffee for a brain long life

引用

Neural Regeneration Research 2024年第1期19卷 158-159页

作者： Chiara Porro antonia Cianciulli maria Antonietta Panaro Department of Clinical and Experimental Medicine University of FoggiaFoggiaItaly(Porro C)Department of BiosciencesBiotechnologies and EnvironmentUniversity of BariBariItaly

Coffee is one of the world's favorite and most popular beverages,the third most popular beverage after water and *** many people,it is an indispensable habit before going to work and a socialization tool for the rest of the *** general,the average consum ption varies from 2 to6 cups per *** are the health implications?Given this consum ption,the benefits are actually greater than the *** is the conclusion of a careful study published in the New England Journal of Medicine(van Dam et al.,2020).

关键词： favorite conclusion life

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessing OSM building completeness for almost 13,000 cities globally

引用

International Journal of Digital Earth 2022年第1期15卷 2400-2421页

作者： Qi Zhou Yuheng Zhang Ke Chang maria antonia Brovelli School of Geography and Information Engineering China University of GeosciencesWuhanPeople’s Republic of China International Research Center of Big Data for Sustainable Development Goals BeijingPeople’s Republic of China Department of Civil and Environmental Engineering Politecnico di MilanoMilanoItaly

OpenStreetMap(OSM)is an essential source for acquiring building data,although such data may suffer from quality *** studies have focused on assessing OSM building data quality but few have been carried out on a global *** study aims to assess OSM building completeness(a quality measure)for 12,975 cities across the *** was achieved by employing population grid data as a proxy for reference building *** only the completeness of each city but also that of the grids within that city was *** assessment results were evaluated based on calculating the overall accuracy and the r-square value between estimated and reference OSM building completeness *** showed that for 75%of cities,the completeness is lower than 20%;no more than 9%of cities have an estimated completeness higher than 80%.The overall accuracies of most countries were higher than 80%.The estimated completeness was also highly correlated with the reference completeness,which verifies the effectiveness of our *** results may be useful for acquiring and updating building data in OSM.A global and open dataset related to OSM building completeness has been made available for public use.

关键词： OpenStreetMap building data data quality population data WorldPop

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：