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情报科学作为认知领域与社会的接口

国外情报科学 1992年第1期10卷 13-18,23页

作者： mari.,Sa 林琳

Visual grading criteria for Japanese larch ( Larix kaempferi ) structural timber from Spain

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Journal of Forestry Research 2020年第6期31卷 2605-2614页

作者： mari.jose Barriola José-Ramón Aira Edgar Lafuente Tknika LHri Aplikatutako Ikerketa eta Berrikuntzako EAEko zentroaZamalbide Auzoa z/g20100 ErrenteriaGipuzkoaSpain Escuela de Ingeniería de la Industria Forestal Agronómica y de la BioenergíaUniversidad de ValladolidUVa-Campus Duques de Sorias/n42005 SoriaSpain Cesefor Centro de Servicios y Promoción Forestal y de su Industria de Castilla y LeónCalle C42005 SoriaSpain

Larch wood is structurally classifi ed in many countries as one of conifers with the highest load-bearing capacity(strength class of C30).The Spanish visual classifi cation regulation only assigns a strength class to 4 pine woods:Laricio pine(Pinus nigra ***),Silvestre pine(Pinus sylvestris L.),Radiata pine(Pinus radiata ***),and Pinaster pine(Pinus pinaster Ait.).This work adds to the number of structurally characterised species by creating a visual classifi cation table for Japanese larch wood(Larix kaempferi(Lamb.)Carr.)which diff erentiates between 2 visual classes,MEG-1 and *** strength values were calculated for each class(fk,MEG-1=31.80 MPa,f k,MEG-2=24.55 MPa),mean module of elasticity(E 0,mean,MEG-1=13,082 MPA,E 0,mean,MEG-2=12,320 MPA)and density(ρk,MEG-1=456.6 kg m−3,ρk,MEG-2=469.1 kg m−3),before fi nally assigning a strength class of C30 to visual class MEG-1,and a strength class of C24 to visual class MEG-2.

关键词： Japanese larch wood Visual grading Strength class Mechanical properties Density

Perceptions and emotions in postoperative recovery of patients with perianal diseases

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World Journal of Psychiatry 2025年第1期15卷 179-184页

作者： Bryan Adrian Priego-Parra jose mari. Remes-Troche Digestive Physiology and Gastrointestinal Motility Lab Instituto de Investigaciones Médico-BiológicasUniversidad VeracruzanaVeracruz 91700Mexico

This article examines the complex relationship between disease perception,negative emotions,and their impact on postoperative recovery in patients with perianal *** conditions not only cause physical discomfort,but also carry a significant emotional burden,often exacerbated by social ***-logical factors,including stress,anxiety,and depression,activate neuroendocrine pathways,such as the hypothalamic–pituitary–adrenal axis,disrupting the gut microbiota and leading to *** disruption can delay wound healing,prolong hospital stay,and intensify *** on the findings of Hou et al,our article highlights the critical role of illness perception and negative emotions in shaping recovery *** advocates for a holistic approach that integrates psychological support and gut microbiota modulation,to enhance healing and improve overall patient outcomes.

关键词： Perianal disease Illness perception Gut microbiota Post-surgical outcomes Microbiota

A New Class of Simple,General and Efﬁcient Finite Volume Schemes for Overdetermined Thermodynamically Compatible Hyperbolic Systems

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Communications on Applied Mathematics and Computation 2024年第3期6卷 1742-1778页

作者： Saray busto Michael Dumbser Departamento de Matemática Aplicada I Universidade de VigoCampus As Lagoas Marcosende s/nE-36310 VigoSpain Department of Civil Environmental and Mechanical EngineeringUniversity of TrentoVia Mesiano 77I-38123 TrentoItaly

In this paper,a new efﬁcient,and at the same time,very simple and general class of thermodynamically compatibleﬁnite volume schemes is introduced for the discretization of nonlinear,overdetermined,and thermodynamically compatibleﬁrst-order hyperbolic *** construction,the proposed semi-discrete method satisﬁes an entropy inequality and is nonlinearly stable in the energy norm.A very peculiar feature of our approach is that entropy is discretized directly,while total energy conservation is achieved as a mere consequence of the thermodynamically compatible *** new schemes can be applied to a very general class of nonlinear systems of hyperbolic PDEs,including both,conservative and non-conservative products,as well as potentially stiff algebraic relaxation source terms,provided that the underlying system is overdetermined and therefore satisﬁes an additional extra conservation law,such as the conservation of total energy *** proposed family ofﬁnite volume schemes is based on the seminal work of Abgrall[1],where for theﬁrst time a completely general methodology for the design of thermodynamically compatible numerical methods for overdetermined hyperbolic PDE was *** apply our new approach to three particular thermodynamically compatible systems:the equations of ideal magnetohydrodynamics(MHD)with thermodynamically compatible generalized Lagrangian multiplier(GLM)divergence cleaning,the uniﬁedﬁrst-order hyperbolic model of continuum mechanics proposed by Godunov,Peshkov,and Romenski(GPR model)and theﬁrst-order hyperbolic model for turbulent shallow waterﬂows of Gavrilyuk et *** addition to formal mathematical proofs of the properties of our newﬁnite volume schemes,we also present a large set of numerical results in order to show their potential,efﬁciency,and practical applicability.

关键词： Overdetermined thermodynamically compatible hyperbolic systems Hyperbolic and thermodynamically compatible(HTC)finite volume schemes Abgrall framework Discrete entropy inequality Nonlinear stability in the energy norm Applications to ideal magnetohydrodynamics(MHD),Godounov-Peshkov-Romenski(GPR)model of continuum mechanics Turbulent shallow water(TSW)ﬂows

CHK2 kinase in the DNA damage response and beyond

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Journal of Molecular Cell Biology 2014年第6期8卷 442-457页

作者： Laura Zannini Domenico Delia Giacomo buscemi Department of Experimental Oncology Fondazione IRCCS Istituto Nazionale dei Tumori Via Amadeo 42 20133 Milan Italy

The serine/threonine kinase CHK2 is a keycomponent of the DNA damage response. In human cells, following genotoxic stress, CHK2 is activated and phosphorylates 〉20 proteins to induce the appropriate cellular response, which, depending on the extent of damage, the cell type, and other factors, could be cell cycle checkpoint activation, induction of apoptosis or senescence, DNA repair, or tolerance of the damage. Recently, CHK2 has also been found to have cellular functions independent of the presence of nuclear DNA lesions. In par- ticular, CHK2 participates in several molecular processes involved in DNA structure modification and cell cycle progression. In this review, we discuss the activity of CHK2 in response to DNA damage and in the maintenance of the biological functions in unstressed cells. These activities are also considered in relation to a possible role of CHK2 in tumorigenesis and, as a consequence, as a target of cancer therapy.

关键词： DNA damage checkpoints apoptosis genomic stability

Biliary complications following liver transplantation

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World Journal of Gastroenterology 2013年第19期19卷 2841-2846页

作者： Gursimran Kochhar jose mari.Parungao Ibrahim A Hanouneh Mansour A Parsi Department of Internal Medicine Cleveland ClinicClevelandOH 44195United States Department of Gastroenterology and Hepatology Digestive Disease InstituteCleveland ClinicClevelandOH 44195United States

Biliary tract complications are the most common complications after liver *** complications are encountered more commonly as a result of increased number of liver transplantations and the prolonged survival of transplant *** complications remain a major source of morbidity in liver transplant patients,with an incidence of 5%-32%.Post liver transplantation biliary complications include strictures(anastomotic and non-anastomotic),leaks,stones,sphincter of Oddi dysfunction,and recurrence of primary biliary disease such as primary sclerosing cholangitis and primary biliary *** risk of occurrence of a specific biliary complication is related to the type of biliary reconstruction performed at the time of liver *** this article we seek to review the major biliary complications and their relation to the type of biliary reconstruction performed at the time of liver tranplantation.

关键词： Liver transplantation Complication Biliary Stricture Leak Endoscopic retrograde cholangiopancreatography

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浅部真菌感染菌种变迁（重点于甲真菌病）

临床皮肤科杂志 1993年第A60期22卷 37-40页

作者： mari.,W 沈丽玉

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瘤胃细菌在瘤胃营养运输中的作用

黑龙江畜牧兽医 1996年第11期 44-45页

作者： mari.,SA 朱玉珍

瘤胃细菌在瘤胃营养运输中的作用（续）ＳｃｏｔｔＡ．Ｍａｒｌｉｎ４瘤胃菌中糖类的运输近年来，开始对以下几种菌的葡萄糖运输机制进行了研究，即瘤胃拟杆菌Ｂ＿１４、溶纤维丁酸弧菌４９、琥珀酸拟杆菌Ｓ＿８５、埃氏巨球形菌Ｂ＿１... 详细信息

瘤胃细菌在瘤胃营养运输中的作用（续）ＳｃｏｔｔＡ．Ｍａｒｌｉｎ４瘤胃菌中糖类的运输近年来，开始对以下几种菌的葡萄糖运输机制进行了研究，即瘤胃拟杆菌Ｂ＿１４、溶纤维丁酸弧菌４９、琥珀酸拟杆菌Ｓ＿８５、埃氏巨球形菌Ｂ＿１３９、反刍月形单孢菌ＨＤ＿４和牛链...

关键词：瘤胃细菌营养运输

Programmed cell death ligand-1(PD-L1) expression by immunohistochemistry: could it be predictive and/or prognostic in non-small cell lung cancer?

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Cancer Biology & Medicine 2016年第2期13卷 157-170页

作者： mari.Mino-Kenudson Department of Pathology Massachusetts General Hospital & Harvard Medical School

Blockade of immune checkpoints has recently emerged as a novel therapeutic strategy in various tumors. In particular,monoclonal antibodies targeting programmed cell death 1(PD-1) or its ligand(PD-L1) have been most studied in lung cancer,and PD-1 inhibitors are now established agents in the management of non-small cell lung cancer(NSCLC). The reports on highprofile clinical trials have shown the association of PD-L1 expression by immunohistochemistry(IHC) with higher overall response rates to the PD-1/PD-L1 axis blockade suggesting that PD-L1 expression may serve as a predictive marker. Unfortunately,however, each PD-1 or PD-L1 inhibitor is coupled with a specific PD-L1 antibody, IHC protocol and scoring system for the biomarker assessment, making the head-to-head comparison of the studies difficult. Similarly, multiple clinical series that correlated PD-L1 expression with clinicopathologic and/or molecular variables and/or survival have reported conflicting *** discrepancy could be explained by the differences in ethnicity and/or histologic types included in the studies, but it appears to be attributed in part to the differences in PD-L1 IHC methods. Thus, orchestrated efforts to standardize the PD-L1 IHC are warranted to establish the IHC as a predictive and/or prognostic biomarker in NSCLC.

关键词： PD-L1 PD- 1 immunohistochemistry predictive biomarker