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The size of Metastasis in the Sentinel Node Is a Predictor of Additional Non-Sentinel Node Positivity

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Journal of Cancer Therapy 2012年第5期3卷 712-717页

作者： Todd A. Baker Nitin Wadhwani Prabha Rajan Sharfi Sarker Gerard Aranha margo shoup Holly Mattix-Kramer Constantine Godellas Department of Pathology Loyola University Chicago Stritch School of Medicine Maywood USA Department of Preventative Medicine and Epidemiology Loyola University Chicago Stritch School of Medicine Maywood USA Department of Surgery Loyola University Chicago Stritch School of Medicine Maywood USA

Background: The need for axillary lymph node dissection (ALND) when sentinel lymph nodes (SLN) contain micrometastasis is controversial. The purpose of this study was to determine if the size of tumor in the SLN corresponds with additional positive non-sentinel lymph nodes (non-SLN) in pT1 breast cancer. Methods: This retrospective review of 483 patients with pT1 breast cancer identified 96 patients with tumor positive SLN biopsies between June 1999 and February 2010. The size of SLN metastasis and the number of tumor positive non-SLN were recorded using AJCC criteria. Receiver operating characteristic analysis was used to discriminate the SLN size with the optimal sensitivity, specificity and likelihood ratios (LR) for additional positive non-SLN. Results: Among 96 patients with a tumor positive SLN, 41% (n = 39) had micrometastasis, and 59% (n = 57) had macrometastasis. A positive non-SLN was identified after ALND among 18% (n = 7 of 39) with micrometastasis compared with 39% (n = 22 of 57) with macrometastasis (p = 0.04). The size of the SLN metastasis and presence of additional tumor positive non-SLNs corresponds to a positive likelihood ratio of 1.1 for micrometastasis and 1.6 for macrometastasis (95%CI: 0.56 - 0.74). Conclusions: Increased size of tumor in SLN is associated with greater likelihood of non-SLN positivity and should be considered for more aggressive follow-up and therapy.

关键词： Sentinel Node Axillary Lymph Node Dissection (ALND)

Agricultural Systems Management: Optimizing Efficiency and Performance (Books in Soils, Plants, and the Environment)

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丛书名： Books in Soils, Plants, and the Environment, v. 99

2004年

作者： Robert M. Peart W. David shoup

ISBN: (纸本)0824747836

Running a productive agriculture system has always been about having the right tools and the know-how to pursue optimization and efficiency. In the 21st century, the case can be made that the agriculturist's most important tool is not the cultivator, but the computer. While you still need to know how to adapt to the day-to-day challenges of land and climate, just as importantly, you need to know how to make reliable projections based on the manipulation of virtual variables. Practice what you learn with real life examples and practical problem solving exercisesAgricultural Systems Management: Optimizing Efficiency and Performance teaches you how to create strategies using readily available off-the-shelf software, spreadsheets, and Internet material to meet the challenges commonly faced in agricultural production, processing, and management. The text provides the step-by-step direction necessary to allow you to obtain optimal results in field and livestock operations, machinery selection, and the planning/forecasting of crops and yield

关键词： Agricultural systems

来源：畅想之星图书光盘版（南... 评论

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通过停车收费筹措公共服务资金

城市交通 2016年第6期14卷 75-87,96页

作者： Donald shoup 袁泉姜昕加州大学洛杉矶分校美国加利福尼亚州洛杉矶90095 南加州大学美国加利福尼亚州洛杉矶90089 斯坦福大学美国加利福尼亚州斯坦福94305

很多城市的低收入社区面临两大突出难题:超负荷的路内停车和低配置的公共服务。通过构建一项政策可以同时解决这两个难题:基于市场价格征收路内停车费,并将其收入用于本地公共服务运营。基于北京一处胡同改善项目发现,通过合理收取停车... 详细信息

很多城市的低收入社区面临两大突出难题:超负荷的路内停车和低配置的公共服务。通过构建一项政策可以同时解决这两个难题:基于市场价格征收路内停车费,并将其收入用于本地公共服务运营。基于北京一处胡同改善项目发现,通过合理收取停车费,该社区用于卫生、治安、景观和停车管理的投资能够在不到三年内回收。同时,该项目社区中只有35%的住户拥有私人小汽车,拥车住户的家庭年收入是无车住户的近3倍。

关键词：停车公共财政土地经济社区公平性

Genetic architecture of quantitative trait loci(QTL)for FHB resistance and agronomic traits in a hard winter wheat population

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The Crop Journal 2023年第6期11卷 1836-1845页

作者： Yuzhou Xu Yaoguang Li Ruolin Bian Guorong Zhang Allan K.Fritz Yanhong Dong Lanfei Zhao Yunfeng Xu Nida Ghori Amy Bernardo Paul StAmand Jessica L.shoup Rupp Myron Bruce Wei Wang Eduard Akhunov Brett Carver Guihua Bai Department of Agronomy Kansas State UniversityManhattanKS 66506USA Department of Plant Pathology University of MinnesotaSt.PaulMN 55108USA Hard Winter Wheat Genetics Research Unit USDAManhattanKS 66506USA Department of Plant Pathology Kansas State UniversityManhattanKS 66506USA Department of Plant and Soil Sciences Oklahoma State UniversityStillwaterOK 74078USA

Wheat resistance to Fusarium head blight(FHB)has often been associated with some undesirable agronomic *** study the relationship between wheat FHB resistance and agronomic traits,we constructed a linkage map of single nucleotide polymorphisms(SNPs)using an F6:8 population from G97252W*** two hard winter wheat parents showed contrasts in FHB resistance,plant height(HT),heading date(HD),spike length(SL),spike compactness(SC),kernel number per spike(KNS),spikelet number per spike(SNS),thousand-grain weight(TGW)and grain size(length and width).Quantitative trait locus(QTL)mapping identified one major QTL(***-2DS)on chromosome arm 2DS for the percentage of symptomatic spikelets(PSS)in the spike,deoxynivalenol(DON)content and Fusarium damaged kernel(FDK).This QTL explained up to 71.8%of the phenotypic variation for the three FHB-related traits and overlapped with the major QTL for HT,HD,SL,KNS,SNS,TGW,and grain *** on chromosome arms 2AL,2DS,3AL and 4BS were significant for the spike and grain traits measured.G97252W contributed FHB resistance and high SNS alleles at ***-2DS,high KNS alleles at the QTL on 2AL and 2DS,and high TGW and grain size alleles at QTL on 3AL;whereas G97380A contributed high TGW and grain size alleles at the QTL on 2AL and 2DS,respectively,and the high KNS allele at the 4BS *** ***-2DS with positive alleles for spike and grain traits from other chromosomes may simultaneously improve FHB resistance and grain yield in new cultivars.

关键词： Wheat Fusarium head blight FHB resistance Developmental and yield traits Pleiotropic QTL

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如何成为一名成功的大学生

英语沙龙（高中） 2010年第6期 28-30页

作者： Luann shoup 刘佳

如何成为一名成功的大学生？也许由于每个人对成功的定义不同，答案也各不相同。但是对一名大学生来说，学业毕竟是最重要的。因为今天你所做的直接决定明天你能得到的。为了不给自己的青春留下遗憾，从今天起，树立目标并为之奋斗，努... 详细信息

如何成为一名成功的大学生？也许由于每个人对成功的定义不同，答案也各不相同。但是对一名大学生来说，学业毕竟是最重要的。因为今天你所做的直接决定明天你能得到的。为了不给自己的青春留下遗憾，从今天起，树立目标并为之奋斗，努力开创属于自己的美好明天!

关键词：英语翻译方法译文课外阅读

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停车受益区

城市交通 2023年第5期21卷 100-112,127页

作者： Donald shoup 冯苏苇(译) 加利福尼亚大学洛杉矶分校城市规划系美国加利福尼亚州洛杉矶90095-1656 上海财经大学公共经济与管理学院上海200433

外侧车道停车位通常拥挤不堪,驾驶人巡游寻找稀缺的空停车位,造成交通拥堵、空气污染,并产生CO_(2)。为了避免这些问题,一些城市建立停车受益区,对外侧车道停车按照市场价格收取停车费,并将收入用于改善收费街区的公共服务。一项对曼哈... 详细信息

外侧车道停车位通常拥挤不堪,驾驶人巡游寻找稀缺的空停车位,造成交通拥堵、空气污染,并产生CO_(2)。为了避免这些问题,一些城市建立停车受益区,对外侧车道停车按照市场价格收取停车费,并将收入用于改善收费街区的公共服务。一项对曼哈顿上西区的案例研究发现,对目前尚未收费的外侧车道停车位按照市场价格收取停车费,每年每个街区可以减少22 t CO_(2)排放量,并且每年至少产生户均1025美元(约合人民币7469元)的收入用于改善公共服务。

关键词：停车公共财政交通拥堵碳排放公平

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工程常用数学的计算机处理

工程常用数学的计算机处理

作者： T.E.·肖普 T.E.·shoup

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寻找路内停车泊位产生的车辆巡游

城市交通 2012年第1期10卷 84-88页

作者： Donald shoup 耿雪朱跃华加州大学洛杉矶分校洛杉矶ca900951656 中国城市规划设计研究院北京100037 北京市城市规划设计研究院北京100045

为寻找路内停车泊位在道路上巡游的车辆是造成交通拥堵的原因之一。首先指出路内停车低价与路外停车高价共同刺激驾驶人选择巡游而非使用路外停车场(库)。其次针对洛杉矶的巡游开展调查,得到车辆平均巡游时耗和距离,并得出每年由此产生... 详细信息

为寻找路内停车泊位在道路上巡游的车辆是造成交通拥堵的原因之一。首先指出路内停车低价与路外停车高价共同刺激驾驶人选择巡游而非使用路外停车场(库)。其次针对洛杉矶的巡游开展调查,得到车辆平均巡游时耗和距离,并得出每年由此产生的车辆行驶里程、时间浪费、燃油消耗及CO2排放。然后通过分析路内停车价格与车辆巡游的关系,提出城市全日泊位使用率大约为85%时,停车泊位处于供需平衡状态,停车价格较合理。接着以加利福尼亚格雷伍德城停车价格制定及停车收益使用为例,给出停车增量融资的收益回馈方式。最后指出,为了减少拥堵、降低温室气体排放、改善街区环境等,城市应制定合理的路内停车价格并将产生的收益用于改善公共服务。

关键词：停车管理路内停车车辆巡游停车价格收益管理

Technology development for ultraintense all-OPCPA systems

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High Power Laser Science and Engineering 2019年第1期7卷 27-37页

作者： J.Bromage S.-W.Bahk I.A.Begishev C.Dorrer M.J.Guardalben B.N.Hoffman J.B.Oliver R.G.Roides E.M.Schiesser M.J.shoup III M.Spilatro B.Webb D.Weiner J.D.Zuegel Laboratory for Laser Energetics University of Rochester

Optical parametric chirped-pulse amplification(OPCPA) [Dubietis et al., Opt. Commun. 88, 437(1992)] implemented by multikilojoule Nd:glass pump lasers is a promising approach to produce ultraintense pulses(>1023 W/cm2).Technologies are being developed to upgrade the OMEGA EP Laser System with the goal to pump an optical parametric amplifier line(EP OPAL) with two of the OMEGA EP beamlines. The resulting ultraintense pulses(1.5 kJ, 20 fs,1024 W/cm2) would be used jointly with picosecond and nanosecond pulses produced by the other two beamlines. A midscale OPAL pumped by the Multi-Terawatt(MTW) laser is being constructed to produce 7.5-J, 15-fs pulses and demonstrate scalable technologies suitable for the upgrade. MTW OPAL will share a target area with the MTW laser(50 J, 1 to 100 ps), enabling several joint-shot configurations. We report on the status of the MTW OPAL system, and the technology development required for this class of all-OPCPA laser system for ultraintense pulses.

关键词： nonlinear optics optical parametric chirped-pulse amplification ultrafast lasers ultraintense lasers