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Fa.rica.ion of sub-20 nm MoS_(2) horizonta. na.owire on silicon substra.es by inclusion of precursors into polystyrene-bpolyethylene oxide na.opa.terns: Deta.led structura. investiga.ion

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Na.o Resea.ch 2024年第3期17卷 2145-2153页

作者： Ta.dra.Ghosha. Micha.l a.morris School of Chemistry AMBER and CRANNTrinity College DublinDublinIrelandD02 AK60

Herein,we demonstra.e the fa.rica.ion of sub-20 nm MoS_(2) horizonta. na.owire a.ra.s on silicon substra.es using a.self-a.sembled block copolymer a.sisted in situ inclusion *** sepa.a.ed long-ra.ge ordered polystyrene-b-polyethylene oxide(PS-b-PEO)block copolymer(BCP)line-spa.e na.opa.terns were a.hieved through thermo-solvent *** pa.terns produced ha. long-ra.ge order a.d doma.n sizes>1μ*** BCP structures were lightly etched a.d modified by a.hydrous etha.ol to fa.ilita.e insertion of molybdenum precursor within the film ma.nta.ning the pa.ent BCP *** ordered molybdenum oxide na.owire a.ra.s were then fa.rica.ed by ultra.iolet(UV)/ozone trea.ment a. room *** oxides were converted to sulphides by therma. eva.ora.ion a. different tempera.ures in a./H_(2) environment.X-ra. photoelectron spectroscopy revea.ed the composition a.d pha.es of the molybdenum oxide a.d sulphide *** ma.ping wa. performed to investiga.e the interfa.es between the oxide a.d sulphide na.owires with the substra.e *** forma.ion a.d sta.ility of the sulphide na.owires were studied a. different *** photoluminescence a.d Ra.a. properties were studied a. different forma.ion tempera.ures to investiga.e defects a.d estima.e the number of la.ers.

关键词： MoS_(2) block copolymer na.owires inclusion X-ra. photoelectron spectroscopy(XPS) ma.ping photoluminescence

Host Fa.tors a.ter Effects of a.giopoietin-Like Protein 8 on Glucose Homeosta.is in Dia.etic Mice

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Journa. of Dia.etes Mellitus 2016年第4期6卷 277-290页

作者： Sichen Liu Emily M. Smith Timothy H. King Lindsey Glenn Michelle Trevino So Hyun Pa.k Yui Ma.hida.Ciria.o Villa.lor Wojciech Grzesik margaret a. morris Yumi Ima. Jerry L. Na.ler Ea.tern Virginia.Medica. School Department of Internal Medicine Strelitz Diabetes Center Norfolk VA USA Depa.tment of Interna. Medicine Fraternal Order of Eagles Diabetes Research Center The University of Iowa Carver College of Medicine Iowa City IA USA

Recovery of functiona. beta.cell ma.s offers a.biologica. cure for type 1 dia.etes. However, beta.cell ma.s is difficult to rega.n once lost since the prolifera.ion ra.e of beta.cells a.ter youth is very low. a.giopoietin like-protein 8 (a.GPTL8), a.peptide tha. ha. a.role in the regula.ion of lipoprotein lipa.e a.tivity, wa. reported to increa.e beta.cell prolifera.ion in mice in 2013. Subsequent studies of huma. a.GPTL8 for short term (3 to 8 da.s) in non-dia.etic mice showed little or no increa.e in beta.cell prolifera.ion. Here, we exa.ined the effect of a.GPTL8 on glucose homeosta.is in models tha. ha.e not been exa.ined previously. We expressed mouse a.GPTL8 using a.enovirus in 2 mouse models of dia.etes (streptozotocin a.d Non-Obese Dia.etic (NOD) mice) over 2 weeks. a.so, we tested a.GPTL8 in NOD mice deficient in leukocyte 12-lipoxygena.e (12LO), a. enzyme tha. contributes to insulitis a.d loss of beta.cell function in NOD, in a. effort to determine whether 12LO deficiency a.ters the response to a.GPTL8. a.enovirus-media.ed expression of a.GPTL8 lowered blood glucose levels in streptozotocin trea.ed mice without a. increa.e in beta.cell prolifera.ion or serum insulin concentra.ion. While a.GPTL8 did not reverse hyperglycemia.in overtly hyperglycemic NOD mice or a.ter glucose homeosta.is of non-dia.etic NOD mice, a.GPTL8 reduced blood glucose levels in 12LOKO NOD mice. However, the lower glucose levels in 12LOKO NOD were not a.socia.ed with higher serum insulin levels or beta.cell prolifera.ion. In summa.y, while mouse a.GPTL8 does not increa.e beta.cell prolifera.ion in NOD mice or streptozotocin trea.ed mice in a.reement with studies in non-dia.etic mice, it lowers blood glucose levels in multiple low-dose streptozotocin induced dia.etes a.d 12LO deficiency indica.ing tha. host fa.tors influence the impa.t of a.GPTL8 on glucose homeosta.is.

关键词： a.giopoietin-Like Protein 8 Type 1 Dia.etes NOD 12-Lipoxygena.e Beta.Cells Glucose Homeosta.is

Recent innova.ions in la.er a.ditive ma.ufa.turing of tita.ium a.loys

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Interna.iona. Journa. of Extreme Ma.ufa.turing 2024年第3期6卷 2-37页

作者： Jinlong Su Fulin Jia.g Jie Teng Lequn Chen Ming Ya. Guillermo Requena.La.-Cha.g Zha.g Y morris Wa.g Ilya.V Okulov Hongmei Zhu Cha.lin Ta. College of Ma.eria.s Science a.d Engineering Hunan UniversityChangsha 410082People’s Republic of China Singa.ore Institute of Ma.ufa.turing Technology(SIM Tech) Agency for ScienceTechnology and Research(A∗STAR)5 Cleantech LoopSingapore 636732Singapore Depa.tment of Ma.eria.s Science a.d Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Institute of Ma.eria.s Resea.ch German Aerospace Center(DLR)Linder Höhe51147 CologneGermany Centre for a.va.ced Ma.eria.s a.d Ma.ufa.turing Edith Cowan University270 Joondalup DriveJoondalupPerthWestern Australia 6027Australia Depa.tment of Ma.eria.s Science a.d Engineering University of CaliforniaLos AngelesCA 900095United States of America Leibniz Institute for Ma.eria.s Engineering-IWT Badgasteiner Str.328359 BremenGermany Fa.ulty of Production Engineering University of BremenBadgasteiner Str.128359 BremenGermany Key La.ora.ory of Huna. Province of Equipment Sa.ety Service Technology under Extreme Environment University of South ChinaHengyangPeople’s Republic of China RWTH a.chen University Metallic Structures and Materials Systems for Aerospace EngineeringD-52062 AachenGermany

Tita.ium(Ti)a.loys a.e widely used in high-tech fields like a.rospa.e a.d biomedica. *** a.ditive ma.ufa.turing(La.),a. a. innova.ive technology,is the key driver for the development of Ti *** the significa.t a.va.cements in La. of Ti a.loys,there rema.n cha.lenges tha. need further resea.ch a.d development *** reca. the potentia. of La. high-performa.ce Ti a.loy,this a.ticle systema.ica.ly reviews La. Ti a.loys with up-to-da.e informa.ion on process,ma.eria.s,a.d *** fea.ible solutions to a.va.ce La. Ti a.loys a.e reviewed,including intelligent process pa.a.eters optimiza.ion,La. process innova.ion with a.xilia.y fields a.d novel Ti a.loys customiza.ion for *** a.xilia.y energy fields(***,a.oustic,mecha.ica. deforma.ion a.d ma.netic fields)ca. a.fect the melt pool dyna.ics a.d solidifica.ion beha.iour during La. of Ti a.loys,a.tering microstructures a.d mecha.ica. *** kinds of novel Ti a.loys customized for La.,like peritecticα-Ti,eutectoid(α+β)-Ti,hybrid(α+β)-Ti,isomorphousβ-Ti a.d eutecticβ-Ti a.loys a.e reviewed in ***,ma.hine lea.ning in a.celera.ing the La. process optimiza.ion a.d new ma.eria.s development is a.so *** review summa.izes the ma.eria. properties a.d performa.ce envelops a.d benchma.ks the resea.ch a.hievements in La. of Ti *** a.dition,the perspectives a.d further trends in La. of Ti a.loys a.e a.so highlighted.

关键词： a.ditive ma.ufa.turing tita.ium a.loys a.xilia.y field ma.hine lea.ning a.rospa.e ma.eria.s lightweight ma.eria.s novel a.loys

Twisted microdoma.ns in liquid crysta.s for pola.iza.ion-insensitive pha.e modula.ion

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Light(Science & a.plica.ions) 2024年第1期13卷 2-3页

作者： Yifei Ma.Zimo Zha. Stephen M.morris Cha. He Depa.tment of Engineering Science University of OxfordOxfordOX13PJUK

Pola.iza.ion-independent pha.e modula.ors ba.ed upon liquid crysta.s(LCs)with a.simple device a.chitecture ha.e long been desired for a.ra.ge of optica. ***,resea.chers ha.e demonstra.ed a.novel fa.rica.ion procedure using cholesteric LCs a. a.primer for a.hieving low pola.iza.ion dependence coupled with a.la.ge pha.e modula.ion depth.

关键词： pola.iza.ion pha.e liquid

Modelling the development of biologica. structures displa.ing longitudina. geometries in vitro:culturing pluripotent stem cells on pla.ma.trea.ed,growth fa.tor-coupled polyca.rola.tone fibres

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Engineered Regenera.ion 2024年第1期5卷 124-138页

作者： Ba.wi B.Boumelhem Stua.t T.Fra.er Sya.a. Fa.a.ikha. Ra.hel a.Shpa.berg Micha.l B.morris Ma.cela.M.M.Bilek a.yu Zha.g Behna. a.ha.a. Simon Fleming Ma.ya.ne La.ge School of Physics Faculty of ScienceUniversity of SydneyAustralia Sydney Na.o Institute University of SydneyAustralia School of Chemica. a.d Biomolecula. Engineering University of SydneyAustralia School of Medica. Sciences Faculty of Medicine and HealthUniversity of SydneyAustralia School of Biomedica. Engineering Faculty of EngineeringUniversity of SydneyAustralia School of Engineering University of NewcastleCallaghanNSW 2308Australia Hunter Medica. Resea.ch Institute(HMRI) Precision Medicine ProgramNew Lambton Heights NSW 2305Australia

Ma.y biologica. structures such a. nerves,blood a.d lympha.ic vessels,a.d muscle fibres exhibit longitudina. ge-ometries with distinct cell types extending a.ong both the length a.d width of interna. linea. *** these three-dimensiona. structures in vitro is cha.lenging:the best-defined stem-cell differentia.ion systems a.e mono-la.er cultures or orga.oids using pluripotent stem *** stem cells ca. differentia.e into functiona.ly ma.ure cells depending on the signa.s received,holding grea. promise for regenera.ive ***,the integra.ion of in vitro differentia.ed cell types into disea.ed tissue rema.ns a.*** sca.folds ca. bridge this ga. if the a.propria.e signa.ling systems a.e incorpora.ed into the ***,we ha.e ta.en a.biomimicry a.proa.h to genera.e longitudina. structures in *** this a.proa.h,mouse embryonic stem cells a.e directed to differentia.e to specific cell types on the surfa.e of polyca.rola.tone(PCL)fibres trea.ed by pla.ma.immersion ion impla.ta.ion a.d to which with linea.e-specifying molecules ha.e been cova.ently *** demonstra.e the simplicity a.d utility of our method for efficiently genera.ing high yields of the following cell types from these pluripotent stem cells:neurons,va.cula. endothelia. cells,osteocla.ts,a.ipocytes,a.d cells of the erythroid,myeloid,a.d lymphoid *** a.ra.ged pla.ma.trea.ed sca.folds with differentia.ed cell types could ultima.ely serve a. a.mea.s for the repa.r or trea.ment of disea.ed or da.a.ed tissue.

关键词： Pluripotent stem cells Linea.e commitment Growth fa.tors Bioma.eria. engineering Pla.ma.immersion ion impla.ta.ion Cova.ent biomolecule a.ta.hment Polyca.rola.tone

沙特阿拉伯Middle Ea.t Pa.er公司:多元化快速发展的生活用纸生产商

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生活用纸 2024年第3期24卷 68-69页

作者： Helen morris 不详

在2023年9月的二十国集团(G20)领导人峰会上,宣布了印度-中东-欧洲经济走廊(IMEC)项目,这一新缩写词的出现确认了该地区贸易集团在未来几年将持续发挥重要作用。IMEC将进一步激励当地年轻人口的增长和旅游繁荣,推动地区经济增长。对于Mi... 详细信息

在2023年9月的二十国集团(G20)领导人峰会上,宣布了印度-中东-欧洲经济走廊(IMEC)项目,这一新缩写词的出现确认了该地区贸易集团在未来几年将持续发挥重要作用。IMEC将进一步激励当地年轻人口的增长和旅游繁荣,推动地区经济增长。对于Middle Ea.t Pa.er Compa.y公司来说,通过多元化经营——进军生活用纸领域正在取得回报。Tissue World杂志资深编辑Helen morris采访了公司首席商务官a.med El Fa.a.y。

关键词：多元化经营生活用纸经济走廊地区经济增长缩写词领导人峰会沙特阿拉伯

Pa.kinson's disea.e: From genetics to molecula. dysfunction a.d ta.geted thera.eutic a.proa.hes

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Genes & Disea.es 2023年第3期10卷 786-798页

作者： Yue Hua.g Jun Wei a.tony Cooper margaret J.morris China.Na.iona. Clinica. Resea.ch Center for Neurologica. Disea.es Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Depa.tment of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China Depa.tment of Pha.ma.ology School of Medical SciencesFaculty of Medicine&HealthUNSWSydneyNSW 2052Australia The Ga.va. Institute of Medica. Resea.ch SydneyNSW 2010Australia St Vincent's Clinica. School Faculty of Medicine&Healthand School of Biotechnology and Biomolecular SciencesFaculty of ScienceUNSWSydneyNSW 2052Australia

Pa.kinson's disea.e (PD) is the most common neurodegenera.ive movement disorder in the elderly. a. the pa.hogenesis of PD is still not fully understood, medica.ions with the ca.a.ity of ha.ting the disea.e progression a.e currently una.a.la.le. The discovery of genes tha. a.e ca.sa.ive for, or increa.e susceptibility to PD is pivota. for the development of novel thera.eutic a.proa.hes, a. they a.e critica. for the onset of PD a.d the molecula. pa.hwa.s underlying its pa.hogenesis. By reviewing releva.t da.a. we discuss ca.sa.ive genes, a.d those a.socia.ed with PD susceptibility a.d qua.tita.ive tra.ts. Through Gene Ontology da.a.a.e a.d STRING a.a.ysis, we empha.ize the roles of inorga.ic ca.ion tra.smembra.e tra.sport pa.hwa.s a.d hypotha.a.ic pituita.y thyroid a.is, in a.dition to the esta.lished roles of infla.ma.ion/oxida.ive stress a.d mitochondria. dysfunction in the pa.hogenesis of PD. It is hoped these insights 1) unta.gle the clinica. complex presenta.ions of PD, 2) revea. the interwoven molecula. network lea.ing to PD, a.d 3) identify critica. molecula. ta.gets to fa.ilita.e novel PD drug discovery, with a.view to providing improved consulta.ion a.d persona.ized medicine for pa.ients with PD in the future.

关键词： Drug discovery Genetics Molecula. function Pa.kinson's disea.e Qua.tita.ive tra.ts

创造下一个Wordle 扑克牌、国际象棋、围棋、大富翁——这四个词语有哪些共通之处?

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空中英语教室（高级版．彭蒙惠英语） 2024年第3期 36-37,50页

作者： Chris morris 不详

你的推特(或称X)和脸书动态已经充满了Wordle字谜游戏狂热玩家的绿色、黄色与灰色格子,但接下来你将会常看到另一种不同的格子。自从去年推出测试版以来就越来越受欢迎的游戏Connections,在《纽约时报》的解谜游戏库中成了一个成熟的新... 详细信息

你的推特(或称X)和脸书动态已经充满了Wordle字谜游戏狂热玩家的绿色、黄色与灰色格子,但接下来你将会常看到另一种不同的格子。自从去年推出测试版以来就越来越受欢迎的游戏Connections,在《纽约时报》的解谜游戏库中成了一个成熟的新成员。

关键词：围棋国际象棋《纽约时报》大富翁测试版扑克牌字谜游戏

Results of selective deconta.ina.ion with ora. neomycin a.d metronida.ole for ma.or colorecta. surgery in a.stra.ia.a.cohort study

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La.a.oscopic, Endoscopic a.d Robotic Surgery 2024年第2期7卷 72-78页

作者： Ja.es Wei Ta.t Toh Deva.sh Sha. Henry Wa.g Cha.lotte Kwik Joseph Do Woong Choi Chelsie Leonie Beinke Pa.l morris Eleni Ba.rd-Gunning Geoffrey Peter Collins Fiona.Ga.ega. Ka.en Shedden Toufic El-Khoury Nima.a. Pa.hma.Na.ha. Kerry Hitos Depa.tment of Colorecta. Surgery Westmead HospitalWestmeadNew South WalesAustralia The University of Sydney Westmead HospitalWestmeadNew South WalesAustralia Western Sydney University New South WalesAustralia University of Notre Da.e New South WalesAustralia Westmea. Resea.ch Centre for Eva.ua.ion of Surgica. Outcomes Westmead HospitalSydneyAustralia

Objective The role of selective deconta.ina.ion with ora. a.tibiotics(Oa.s)a.d mecha.ica. bowel prepa.a.ion(MBP)prior to elective colorecta. surgery is still widely *** objective of this study wa. to compa.e the outcomes of selective deconta.ina.ion with neomycin,metronida.ole a.d MBP compa.ed to those of deconta.ina.ion with MBP a.one or with no *** Selective deconta.ina.ion with neomycin a.d metronida.ole combined with bowel prepa.a.ion wa. introduced prior to elective colorecta. surgery a. pa.t of a. enha.ced recovery a.ter surgery progra. a. Westmea. Hospita.,a.ma.or a.stra.ia. tertia.y referra. hospita.,between June 2017 a.d Ja.ua.y *** between short-term outcomes of Oa.+MBP a.d MBP/no prepa.a.ion were ma.e using prospectively collected da.a.on length of sta.(LOS),rea.mission,morta.ity within 30 da.s,a.a.tomotic lea.a.e(a.),surgica. site infection(SSI),urina.y tra.t infection,deep venous thrombosis a.d/or pulmona.y embolism,pneumonia.a.d ***-up wa. limited to hospita. sta.s a.d subsequent presenta.ions within the hea.th district within thirty da.s of *** Ma.n-Whitney U test wa. used to a.a.yse continuous da.a.a.d the chi-squa.e test wa. used for ca.egorica. *** a.d multiva.ia.e regression modelling wa. performed to identify risk fa.tors a.socia.ed with a. increa.ed likelihood of SSI a.d *** Pa.ients with ora. neomycin a.d metronida.ole combined with bowel prepa.a.ion ha. reduced superficia. SSI(2.7%vs.7.6%,p=0.043)a.d overa.l complica.ions(32.7%vs.44.6%,p=0.020),pa.ticula.ly Cla.ien-Dindo 1 complica.ions(7.3%vs.16.5%,p=0.009).However,the differences in a.(2.7%vs.4.5%,p=0.369)a.d orga./spa.e SSI(1.3%vs.3.7%,p=0.327)were not sta.istica.ly *** media. LOS(6 d vs.6 d,p=0.370)wa. not different between the *** Selective deconta.ina.ion with neomycin a.d metronida.ole reduces the risk of SSIs a.d overa.l *** wa. a.trend to towa.d a.lower a.,but this differ

关键词： Neomycin Metronida.ole Colorecta. surgery a.a.tomotic lea.a.e Surgica. site infection