检索结果-南通市图书馆

Outcomes of a non-randomised audit of single pigtail suture stents in urolithiasis management of Asian patients in Singapore

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Urology 2024年第2期11卷 324-330页

作者： Ee Jean Lim Zhen wei Choo Reshma Mangat Pradeep Durai Sarvajit Biligere Yiquan Tan Loh Hin Yeung marcus Nicole Andrea Seet Li Ting chin Tiong Heng Stefania Ferreti Vineet Gauhar Urology Department Singapore General HospitalSingapore Urology Department Tan Tock Seng HospitalSingapore Urology Department Ng Teng Fong HospitalSingapore Urology Department Azienda Ospedaliera-Uiversitaria(Hospital and University of Parma)ParmaItaly

Objective:Double-J(DJ)ureteric stents are commonly placed perioperatively for semirigid or flexible ureteroscopic renal *** is believed that lesser stent material within the bladder mitigates stent-related *** study aimed to evaluate the J-Fil ureteral stent,a single pigtail suture stent compared with conventional DJ stent in relation to stent symptoms in an Asian population undergoing ureterorenal ***:Based on internal audit committee recommendation approval,the records of 50 patients retrieved,available data of 41 patients who were prospectively enrolled into two groups(Group 1[J-Fil stent group],n=21 and Group 2[DJ stent group],n=20)between August 2020 to January 2021,were *** compared were nature of procedure,stone location and size,ease of deployment or removal,and complications.A modified universal stent symptom questionnaire was used to assess morbidity of stent symptoms within 48 h of insertion and at ***:Both groups had similar median age,distribution in male to female ratio,and stone *** overall median universal stent symptom questionnaire score at insertion was similar for bladder pain,flank or loin pain,and quality of life between Group 1 and 2;however,at removal Group 1 fared significantly better than Group 2,especially for flank or loin pain and pain at *** groups had similar ease in insertion with no hospital ***:Our audit favoured the single pigtail suture stent in Asian ureters in mitigating stent-related *** showed a good safety profile with easy deployment and *** promises a new standard in stenting.

关键词： Stent Ureteroscopy Pigtail suture stent Asianpatient Flexible ureteroscopic renal surgery

Designing a Secure and Scalable Data Sharing Mechanism Using Decentralized Identifiers(DID)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第10期141卷 809-822页

作者： Iuon-Chang Lin I-Ling Yeh ching-Chun Chang Jui-Chuan Liu chin-Chen Chang Department of Management Information Systems National Chung Hsing UniversityTaichung402Taiwan Information and Communication Security Research Center Feng Chia UniversityTaichung407Taiwan Department of Information Engineering and Computer Science Feng Chia UniversityTaichung407Taiwan

Centralized storage and identity identification methods pose many risks,including hacker attacks,data misuse,and single points of ***,existing centralized identity management methods face interoperability issues and rely on a single identity provider,leaving users without control over their ***,this paper proposes a mechanism for identity identification and data sharing based on decentralized *** scheme utilizes blockchain technology to store the identifiers and data hashed on the chain to ensure permanent identity recognition and data *** is stored on InterPlanetary File System(IPFS)to avoid the risk of single points of failure and to enhance data persistence and *** the same time,compliance with world wide web Consortium(w3C)standards for decentralized identifiers and verifiable credentials increases the mechanism’s scalability and interoperability.

关键词： Self-sovereign identity decentralized identifier blockchain

Scanning probe lithography on calixarene towards single-digit nanometer fabrication

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Extreme Manufacturing 2020年第3期2卷 104-124页

作者： marcus Kaestner Ivo w Rangelow Institute of Micro-and Nanoelectronics Nanoscale Systems GroupFaculty of Electrical Engineering and Information TechnologyIlmenau University of TechnologyGustav-Kirchhoff-Str.198693 IlmenauGermany

Cost effective patterning based on scanning probe nanolithography(SPL)has the potential for electronic and optical nano-device manufacturing and other nanotechnological *** of the fundamental advantages of SPL is its capability for patterning and imaging employing the same *** is achieved with self-sensing and self-actuating cantilevers,also known as‘active'*** we used active cantilevers to demonstrate a novel path towards single digit nanoscale patterning by employing a low energy(ws for greater control over spatially confined lithography and enhances *** found that at low electron energies,the exposure in ambient conditions required approximately 10 electrons per single calixarene molecule to induce a crosslinking *** sensitivity was 80-times greater than a classical electron beam exposure at 30 *** operating the electro-exposure process in ambient conditions a novel lithographic reaction scheme based on a direct ablation of resist material(positive tone)is presented.

关键词： nanofabrication field-emission scanning probe lithography single nanometer lithography molecular resist

General Three—Dimensional Electromagnetic Model for Nondiolar Transm

在线全文

学校读者我要写书评

暂无评论

测井技术 2000年第4期24卷 262-278页

作者： chin,w C Strata Magnetic Software LL C 美国 Texas Hous

运用Ｍａｘｗｅｌｌ方程组频率域完全有限差分算法求解倾斜层状各向异性介质中一般三维电磁问题。该方法没有Ｂｏｒｎ近似、几何因子近似、混合法以及线性积分方程等的固有缺陷，并具有几项重要性能。第一，发射线圈不再用点状偶极子表... 详细信息

运用Ｍａｘｗｅｌｌ方程组频率域完全有限差分算法求解倾斜层状各向异性介质中一般三维电磁问题。该方法没有Ｂｏｒｎ近似、几何因子近似、混合法以及线性积分方程等的固有缺陷，并具有几项重要性能。第一，发射线圈不再用点状偶极子表示，而是用方位方向赋予复电流的８个等距结点模拟。线圈可以跨多个地层，这有助于模拟薄互层响应。发射线圈可工作在电缆测井只有线圈的模式，或随钻测井钢质钻铤模式。

关键词：三维电磁场电磁测井电磁模型电测井

Docosahexaenoic acid-rich fish oil prevented insulin resistance by modulating gut microbiome and promoting colonic peptide YY expression in diet-induced obesity mice

在线全文

学校读者我要写书评

暂无评论

Food Science and Human wellness 2022年第1期11卷 177-188页

作者： wanxiu Cao Fang Liu Robert wLi Yaoxian chin Yuming wang Changhu Xue Qingjuan Tang College of Food Science and Engineering Ocean University of ChinaQingdao 266003China Key Laboratory of Marine Drugs Ministry of EducationSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China United States Department of Agriculture Agriculture Research Service(USDA-ARS)Animal Genomics and Improvement LaboratoryBeltsvilleMD 20705USA Hainan Tropical Ocean University Sanya 572022China Laboratory for Marine Drugs and Bioproducts Qingdao National Laboratory for Marine Science and TechnologyQingdao 266003China

It is unclear how docosahexaenoic acid(DHA)improves insulin resistance via modulating gut microbiome in obese *** used diet-induced obesity(DIO)mice as a model to study the effects of DHA-rich fish oil(DHA-FO)on host metabolic disorders and colonic ***-FO reduced fat deposition,regulated lipid profiles and alleviated insulin resistance in DIO *** because DHA-FO prevented the permeation of lipopolysaccharide across intestinal epithelial barrier,and promoted peptide YY(PYY)secretion via the mediation of short chain fatty acids receptor(FFAR2)in ***,DHA-FO might regulate PYY expression by reversing microbial dysbiosis,including increasing the abundance ofAkkermansia muciniphila and Lactobacillus,and suppressing the growth of ***-FO also altered gut microbial function(e.g."linoleic acid metabolism")associated with PYY expression(r>0.80,P<0.05).Herein,DHA-FO enhanced insulin action on glucose metabolism by altering gut microbiome and facilitating colonic PYY expression in DIO mice.

关键词： Docosahexaenoic acid Diet-induced obesity Insulin resistance Peptide YY Gut microbiome

Small molecule activators of the p53 response

在线全文

学校读者我要写书评

暂无评论

Journal of Molecular Cell Biology 2019年第3期11卷 245-254页

作者： marcus J.G.w.Ladds Sonia Lain Department of Microbiology Tumor and Cell BiologyBiomedicumSolnavagen 9Karolinska Institutet17165StockholmSweden SciLifeLab Tomtebodavagen 23A171 65SoinaStockholmSweden

Drugging the p53 pathway has been a goal for both academics and pharmaceutical companies since the designation of p53 as the'guardian of the genome'.Through growing understanding of p53 biology,we can see multiple routes for activation of both wild-type p53 function and restoration of mutant p53?In this review,we focus on small molecules that activate wild-type p53 and that do so in a nongenotoxit *** particular,we will describe potential approaches to targeting proteins that alter p53 stability and function through posttranslational modification,affect p53's subcellular localization,or target RNA synthesis or the synthesis of *** plethora of pathways for exploitation of p53,as well as the wide-ranging response to p53 activation,makes it an attractive target for anti-cancer therapy.

关键词： cancer p53 small molecule cell biology cancer therapy

Theoretical Investigations on Photodissociation Dynamics of Deuterated Alkyl Halides CD_(3)CH_(2)F

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

chinese Journal of Chemical Physics 2022年第3期35卷 431-442,I0001页

作者： Shuangfei Gu Chih-Hao chin Tong Zhu John Zeng Hui Zhang Shanghai Engineering Research Center for Molecular Therapeutics and New Drug Development School of Chemistry and Molecular EngineeringEast China Normal UniversityShanghai 200062China NYU-ECNU Center for Computational Chemistry at NYU Shanghai Shanghai 200122China Department of Chemistry New York UniversityNew York 10003USA

The product branching ratio between different products in multichannel reactions is as important as the overall rate of reaction,both in terms of practical applications(*** of combustion or atmosphere chemistry)in understanding the fundamental mechanisms of such chemical reactions.A global ground state potential energy surface for the dissociation reaction of deuterated alkyl halide CD_(3)CH_(2)F was computed at the CCSD(T)/CBS//B3 LYP/aug-cc-p VDZ level of theory for all *** decomposition of CD_(3)CH_(2)F is controversial concerning C-F bond dissociation reaction and molecular(HF,DF,H_(2),D_(2),HD)elimination ***-Kassel-marcus(RRKM)calculations were applied to compute the rate constants for individual reaction steps and the relative product branching ratios for the dissociation products were calculated using the steady-state *** the different energies studied,the RRKM method predicts that the main channel for DF or HF elimination from1,2-elimination of CD_(3)CH_(2)F is through a four-center transition state,whereas D_(2) or H_(2) elimination from 1,1-elimination of CD_(3)CH_(2)F occurs through a direct three-center *** 266,248,and 193 nm photodissociation,the main product CD_(2)CH_(2)+DF branching ratios are computed to be 96.57%,91.47%,and 48.52%,respectively;however,at 157 nm photodissociation,the product branching ratio is computed to be 16.11%.Based on these transition state structures and energies,the following photodissociation mechanisms are suggested:at 266,248,193 nm,CD_(3)CH_(2)F→absorption of a photon→TS5→the formation of the major product CD_(2)CH_(2)+DF;at 157 nm,CD_(3)CH_(2)F→absorption of a photon→D/F interchange of TS1→CDH_(2)CDF→H/F interchange of TS2→CHD_(2)CHDF→the formation of the major product CHD_(2)+CHDF.

关键词： Potential energy surface Photodissociation dynamics Reaction mechanism Rate constant Branching ratio

Enhanced apoptosis in post-liver transplant hepatitis C:Effects of virus and immunosuppressants

在线全文

学校读者我要写书评

暂无评论

world Journal of Gastroenterology 2012年第18期18卷 2172-2179页

作者： Eu Jin Lim Ruth chin Peter w Angus Joseph Torresi Liver Transplant Unit Austin HospitalHeidelbergVictoria 3084Australia Department of Medicine University of MelbourneAustin HealthHeidelbergVictoria 3084Australia Department of Infectious Diseases Austin HospitalHeidelbergVictoria 3084Australia

Hepatitis C(HCV)-infected patients have a poorer survival post-liver transplantation compared to patients transplanted for other indications,since HCV recurrence post-transplant is universal and commonly follows an aggressive *** is increasing evidence that in the non-transplant setting,induction of hepatocyte apoptosis is one of the main mechanisms by which HCV drives liver inflammation and fibrosis,and that HCV proteins directly promote *** studies have shown that post-liver transplant,there is a link between high levels of HCV replication,enhanced hepatocyte apoptosis and the subsequent development of rapidly progressive liver *** the responsible mechanisms remain unclear,it is likely that immunosuppressive drugs play an important *** is well known that immunosuppressants impair immune control of HCV,thereby allowing increased viral *** there is also evidence that immunosuppressants may directly induce apoptosis and this may be facilitated by the presence of high levels of HCV *** HCV and immunosuppressants may synergistically interact to further enhance apoptosis and drive more rapid *** findings suggest that modulation of apoptosis within the liver either by changing immunosuppressive therapy or the use of apoptosis inhibitors may help prevent fibrosis progression in patients with post-transplant HCV disease.

关键词： Hepatitis C Liver transplantation Apoptosis Immunosuppressive agents transforming growth factor-β

Ultracold atomic gases going strong

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2016年第2期3卷 168-170页

作者： Cheng chin James Franck Institute Enrico Fermi InstituteUniversity of Chicago

The year 2015 marks the 20th anniversary of the achievement of Bose-Einstein condensation(BEC)in atomic *** BEC,realized by Eric Cornell,Carl wieman and wolfgang Ketterle in1995,commenced an exciting wave to explore quantum few-and many-body *** from solid state matter and helium superfluids,atomic condensates in the gas phase come with

关键词： body BEC Ultracold atomic gases going strong length