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A probabilistic model to evaluate the effectiveness of main solutions to COVID-19 spreading in university buildings according to proximity and time-based consolidated criteria

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Building Simulation 2021年第6期14卷 1795-1809页

作者： marco D'Orazio Gabriele Bernardini Enrico Quagliarini Department of Construction Civil Engineering and ArchitectureUniversita Politecnica delle Marchevia Brecce Blanche 60131 AnconaItaly

University buildings are one of the most relevant closed environments in which the COVID-19 event clearly pointed out stakeholders'needs toward safety issues,especially because of the possibility of day-to-day presences of the same users(***,teachers)and overcrowding causing long-lasting contacts with possible"infectors".While waiting for the vaccine,as for other public buildings,policy-makers’measures to limit virus outbreaks combine individual’s strategies(facial masks),occupants,capacity and access ***,up to now,no easy-to-apply tools are available for assessing the punctual effectiveness of such *** fill this gap,this work proposes a quick and probabilistic simulation model based on consolidated proximity and exposure-time-based rules for virus transmission confirmed by international health *** building occupancy is defined according to university scheduling,identifying the main"attraction areas"in the building(classrooms,break-areas).Scenarios are defined in terms of occupants’densities and the above-mentioned mitigation *** model is calibrated on experimental data and applied to a relevant university *** demonstrate the model *** particular,it underlines that if such strategies are not combined,the virus spreading can be limited by only using high protection respiratory devices(***3)by almost every *** the contrary,the combination between access control and building capacity limitation can lead to the adoption of lighter protective devices(*** masks),thus improving the feasibility,users'comfort and favorable *** rules to combine acceptable mask filters-occupants,density are thus provided to help stakeholders in organizing users'presences in the building during the pandemic.

关键词： simulation model closed built environment building occupancy crowd models proximity exposure COVID-19

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Spatio-temporal patterns of the Red-footed Falcon's hunting behavior during the nestling period suggest ad hoc conservation policies

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Avian Research 2021年第1期12卷 118-123页

作者： marco Gustin Alessandro Ferrarini Conservation Department BirdLifeLIPU(Lega Italiana Protezione Uccelli)Via Udine 343100 ParmaItaly

The Red-footed Falcon(Falco vespertinus)is a species of high international conservation *** analyzed its hunting behavior at the two largest colonies in Italy during the nestling *** accurate data-loggers,we tracked three adult Red-footed Falcons in June and July,2019 and collected 4703 GPS *** detected clear patterns of hovering and perching activity(HPA)in both time and *** occupied one-third of the Red-footed Falcons’day,and showed two peaks just after sunrise(between 35 and 40%of the monitoring time)and just before sunset(50‒60%)in both June and July,and minimum(20‒30%)at night and during the hottest time interval(10:00 a.m.‒4:00 p.m.).Almost 40%of HPA occurred within 50 m from *** findings,although preliminary,have important implications for the conservation of these two colonies that are located within two Natura 2000 *** detected spatio-temporal patterns of Red-footed Falcons’hunting behavior suggests the creation of two nested protection belts:the inner one is a narrow belt(up to 50 m from the two rows of trees that host the two colonies)with integral conservation,and hopefully increase the alfalfa crops and fallow land,and the outer belt(50 m‒2 km)with optimized agricultural activities.

关键词： Biotelemetry Falco vespertinus Hovering Italy Natura 2000 site Perching

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Novel pathomechanistic insights into lysosomal storage disorders:how neuron-intrinsic cGAS-STING signaling drives disease progression

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Signal Transduction and Targeted Therapy 2024年第9期9卷 3548-3549页

作者： Maximilian Frosch marco Prinz Institute of Neuropathology University of FreiburgFaculty of MedicineFreiburgGermany Signalling Research Centres BIOSS and CIBSS University of FreiburgFreiburgGermany

In their recent paper published in Nature Cell Biology,1 Wang and colleagues defined a pathogenetic mechanism among a variety of lysosomal storage disorders(LSDs)mediating neuronal death and disease *** authors observed neuron-intrinsic activated cGAS-STING signaling triggered by accumulating cytosolic dsDNA,and thus,they provide a valuable target for directed therapies.

关键词： disorders intrinsic death

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Microglia out of place—mapping macrophages across the developing human body

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Cellular & Molecular Immunology 2024年第3期21卷 210-212页

作者： Roman Sankowski marco Prinz Institute of Neuropathology Faculty of MedicineUniversity of FreiburgFreiburgGermany Signalling Research Centres BIOsS and CIBSs University of FreiburgFreiburgGermany

Macrophages(MΦs)are versatile cells found in every *** the body,they work tirelessly to maintain *** this end,they are instructed by their respective niches to express organ-specific genes and proteins,resulting in a variety of cell morphologies and highly specialized functions across different tissues[1].A recent study by Wang et *** single-cell RNA sequencing to comprehensively profile human MΦphenotypes across 19 organs between postconception weeks(PCW)4 and 26[2].This study revealed a surprising diversity of these cells and suggests new avenues of research.

关键词： organs instru

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The intriguing giant deer from the Bate cave (Crete): could paleohistological evidence question its taxonomy and nomenclature?

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Integrative Zoology 2022年第1期17卷 54-77页

作者： Maria Rita PALOMBO marco ZEDDA CNR-IGAG c/o Department of Earth Sciences Sapienza UniversityRomaItaly Department of Veterinary Medicine University of SassariItaly

The research describes for the first time a possible case of pituitary gigantism in fossil mammals,precisely in *** pathology was detected in 2 long bones(tibia and metatarsus)belonging to an individual of an unusual large size found at the Bate cave(Rethymnon,Northern Crete).It formed the basis of Candiacervus major,the largest among the endemic deer species recorded in the Pleistocene-Early Holocene of *** and histomorphological examinations highlighted a reduction in cortical bone thickness and the presence of wide lacunae inside of the bone *** pathological conditions suggest a pituitary gigantism diagnosis also supported by some morphological evidence,such as the extremely elongated distal part of the metatarsal diaphysis,the proportionally small proximal epiphysis,and some bone *** diagnosis of a case of pituitary gigantism as presumed responsible for the extraordinary elongation of the tibia and the metatarsal bone is intriguing as they are,respectively,the paratype and the holotype of the *** species represents a case of a deviation from the“island rule”in Pleistocene large *** new evidence recommends a taxonomic and nomenclatural revision of this *** main outcomes of this research are as follows:(i)a case of pituitary gigantism is described for the first time in an extinct mammal;(ii)it is underlined that paleohistology may provide interesting clues for disentangling taxonomic and nomenclatural issues;(iii)one of the very few cases of gigantism in insular mammals is being questioned.

关键词： Candiacervus major Cretan deer island rule paleohistology pituitary gigantism

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LARM PKM solutions for torso design in humanoid robots

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Frontiers of Mechanical Engineering 2014年第4期9卷 308-316页

作者： marco CECCARELLI Laboratory of Robotics and Mechatronics University of Cassino andSouth Latium Cassino 03043 Italy

Human-like torso features are essential in humanoid robots. In this paper problems for design and operation of solutions for a robotic torso are discussed by referring to experiences and designs that have been developed at Laboratory of Robotics and Mechatronics （LARM） in Cassino, Italy. A new solution is presented with conceptual views as waist-trunk structure that makes a proper partition of the performance for walking and arm operations as sustained by a torso.

关键词： humanoid robots torso design parallelmanipulators (PKM) conceptual design

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Diagnostic detection with cardiac tomography and resonance of extremely rare coronary anomaly:A case report and review of literature

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World Journal of Clinical Cases 2019年第5期7卷 628-635页

作者： Nicolò Schicchi marco Fogante Gian marco Giuseppetti Andrea Giovagnoni Department of Radiology Azienda Ospedaliero-Universitaria Ospedali Riuniti Department of Radiology Università Politecnica delle Marche

BACKGROUND The association of two congenital coronary artery anomalies(CAAs) is extremely rare but represents one of the main cause of sudden cardiac death in young athletes. Although coronary angiography(CX-A) is still widely used in childhood, cardiac magnetic resonance(C-MRI) and cardiac computed tomography(C-CT) have recently taken on an increasing diagnostic role in early detection of CAAs and concomitant congenital cardiac *** SUMMARY A healthy 10-year-old male patient was referred to the Radiological Department of our Institution due to no evidence of left coronary artery in echocardiographic examination. With C-MRI was detected marked myocardial trabeculation and was suspected anomalous origin and course of left circumflex(LCx) artery and of left anterior descending(LAD) artery. With third generation Dual Source C-CT192x2-sections(SOMATOM Force, Siemens, Germany) was confirmed anomalous origin of LCx artery from right pulmonary artery associated with anomalous origin of LAD artery from right coronary artery with course in front of right ventricular outflow tract. The patient underwent surgical treatment with reimplantation of the anomalous LCX and LAD arteries into the wall of ascending aorta, with no postoperative complications. The patient remained asymptomatic and follow-up C-MRI scan four months after operation showed complete success of surgery *** This case highlights the diagnostic potential of C-CT and C-MRI in evaluation of CAAs and of cardiac morphology and functionality, with very low radiation dose and without the risks related to invasive procedure.

关键词： Coronary anomalies Cardiac computed tomography Cardiac magnetic resonance Case report Coronary artery anomalies

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Energy tunnels:concept and design aspects

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Underground Space 2018年第4期3卷 268-276页

作者： marco Barla Alice Di Donna Department of Structural Building and Geotechnical EngineeringPolitecnico di TorinoCorso Duca degli Abruzzi 2410129 TorinoItaly

Geotechnical structures are increasingly employed as energy geostructures in Europe and *** being constructed for their primary structural role,they are equipped to exchange heat with the ground and supply thermal energy for heating and cooling of buildings and de-icing of *** technology can play a fundamental role in the current challenge of addressing the increasing need for clean and renewable sources of *** study investigates the possibility of thermal activation of tunnel ***,attention will be paid on a new energy segment,which can be used together with tunnel boring machine tunneling to create so-called energy *** and mechanical designs need to be developed by making effective use of computational methods to quantify the exploitable heat and assess the possible consequences on the surrounding ground and the structure *** on how to proceed in this direction will be provided in this study,showing how thermo-hydro and thermo-mechanical numerical analyses can be used to achieve a proper and effective design of energy *** examples of possible applications will also be presented.

关键词： Energy tunnel Geothermal energy Heating and cooling Geotechnical design

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Groups Whose Proper Subgroups of Infinite Rank Have Polycyclic Conjugacy Classes

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Algebra Colloquium 2015年第2期22卷 181-188页

作者： Francesco de Giovanni marco Trombetti Dipartimento di Matematica e Applicazioni Universita di Napoli Federico II Complesso Universitario Monte S. Angelo Via Cintia I- 80126 Napoli Italy

A group G is called a PC-group if the factor group G/CG（〈X）^G） is polycyclic for each element x of G. It is proved here that if G is a group of infinite rank whose proper subgroups of infinite rank have the property PC, then G itself is a PC-group, provided that G has an abelian non-trivial homomorphic image. Moreover, under the same assumption, a complete classification of minimal non-PC groups is obtained.

关键词： PC-group minimal non-PC group group of infinite rank

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Potential and progress of studying mountain biodiversity by means of butterfly genetics and genomics

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Journal of Genetics and Genomics 2024年第3期51卷 292-301页

作者： Shuting Wang marco Girardello Wei Zhang State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China cE3c-Centre for Ecology Evolution and Environmental Changes/Azorean Biodiversity GroupFaculdade de Ciencias Agrarias e do AmbienteUniversidade dos Açores9700-042 Angra do HeroísmoTerceiraPortugal

Mountains are rich in biodiversity,and butterflies are species-rich and have a good ecological and evolutionary research *** review addresses the potential and progress of studying mountain biodiversity using butterflies as a *** discuss the uniqueness of mountain ecosystems,factors influencing the distribution of mountain butterflies,representative genetic and evolutionary models in butterfly research,and evolutionary studies of mountain biodiversity involving butterfly genetics and ***,we demonstrate the necessity of studying mountain butterflies and propose future *** review provides insights for studying the biodiversity of mountain butterflies as well as a summary of research methods for reference.

关键词： Mountain ecosystem Butterfly Biodiversity Adaptation Genomics Genetics

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