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Journal of Integrative Medicine 2017年第2期15卷 77-87页

作者： marco Cascella Maria Rosaria Muzio Division of Anesthesia Department of Anesthesia and Pain Medicine Istituto Nazionale Tumori "Fondazione G. Pascale"--IRCCS via Mariano Semmola Naples 80131 Italy Division of Infantile Neuropsychiatry UOMI-Maternal and Infant Health Asl NA 3 SUD Torre del Greco via Marconi Naples 80059 Italy

Chemotherapy-induced peripheral neuropathy （CIPN） is one of the most common and severe adverse effects related to cancer treatment. Unfortunately, although several agents and protocols have been proposed, no prophylactic strategies have yet to be proven useful. Therefore, new alternative therapies have been considered for CIPN prevention. Herbal medicine in Japan, called Kampo medicine, is derived from traditional Chinese medicine. Goshajinkigan （GJG） is a Kampo medicine, that is comprised of ten herbs. The aim of this work is to analyse the results of pre-clinical and clinical studies on the potential applications of GJG in CIPN prevention.

关键词： chemotherapy peripheral neuropathies herbal medicine alternative medicine natural products

LARM PKM solutions for torso design in humanoid robots

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Frontiers of Mechanical Engineering 2014年第4期9卷 308-316页

作者： marco CECCARELLI Laboratory of Robotics and Mechatronics University of Cassino andSouth Latium Cassino 03043 Italy

Human-like torso features are essential in humanoid robots. In this paper problems for design and operation of solutions for a robotic torso are discussed by referring to experiences and designs that have been developed at Laboratory of Robotics and Mechatronics （LARM） in Cassino, Italy. A new solution is presented with conceptual views as waist-trunk structure that makes a proper partition of the performance for walking and arm operations as sustained by a torso.

关键词： humanoid robots torso design parallelmanipulators (PKM) conceptual design

Energy tunnels:concept and design aspects

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Underground Space 2018年第4期3卷 268-276页

作者： marco Barla Alice Di Donna Department of Structural Building and Geotechnical EngineeringPolitecnico di TorinoCorso Duca degli Abruzzi 2410129 TorinoItaly

Geotechnical structures are increasingly employed as energy geostructures in Europe and *** being constructed for their primary structural role,they are equipped to exchange heat with the ground and supply thermal energy for heating and cooling of buildings and de-icing of *** technology can play a fundamental role in the current challenge of addressing the increasing need for clean and renewable sources of *** study investigates the possibility of thermal activation of tunnel ***,attention will be paid on a new energy segment,which can be used together with tunnel boring machine tunneling to create so-called energy *** and mechanical designs need to be developed by making effective use of computational methods to quantify the exploitable heat and assess the possible consequences on the surrounding ground and the structure *** on how to proceed in this direction will be provided in this study,showing how thermo-hydro and thermo-mechanical numerical analyses can be used to achieve a proper and effective design of energy *** examples of possible applications will also be presented.

关键词： Energy tunnel Geothermal energy Heating and cooling Geotechnical design

Diagnostic detection with cardiac tomography and resonance of extremely rare coronary anomaly:A case report and review of literature

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World Journal of Clinical Cases 2019年第5期7卷 628-635页

作者： Nicolò Schicchi marco Fogante Gian marco Giuseppetti Andrea Giovagnoni Department of Radiology Azienda Ospedaliero-Universitaria Ospedali Riuniti Department of Radiology Università Politecnica delle Marche

BACKGROUND The association of two congenital coronary artery anomalies(CAAs) is extremely rare but represents one of the main cause of sudden cardiac death in young athletes. Although coronary angiography(CX-A) is still widely used in childhood, cardiac magnetic resonance(C-MRI) and cardiac computed tomography(C-CT) have recently taken on an increasing diagnostic role in early detection of CAAs and concomitant congenital cardiac *** SUMMARY A healthy 10-year-old male patient was referred to the Radiological Department of our Institution due to no evidence of left coronary artery in echocardiographic examination. With C-MRI was detected marked myocardial trabeculation and was suspected anomalous origin and course of left circumflex(LCx) artery and of left anterior descending(LAD) artery. With third generation Dual Source C-CT192x2-sections(SOMATOM Force, Siemens, Germany) was confirmed anomalous origin of LCx artery from right pulmonary artery associated with anomalous origin of LAD artery from right coronary artery with course in front of right ventricular outflow tract. The patient underwent surgical treatment with reimplantation of the anomalous LCX and LAD arteries into the wall of ascending aorta, with no postoperative complications. The patient remained asymptomatic and follow-up C-MRI scan four months after operation showed complete success of surgery *** This case highlights the diagnostic potential of C-CT and C-MRI in evaluation of CAAs and of cardiac morphology and functionality, with very low radiation dose and without the risks related to invasive procedure.

关键词： Coronary anomalies Cardiac computed tomography Cardiac magnetic resonance Case report Coronary artery anomalies

Groups Whose Proper Subgroups of Infinite Rank Have Polycyclic Conjugacy Classes

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Algebra Colloquium 2015年第2期22卷 181-188页

作者： Francesco de Giovanni marco Trombetti Dipartimento di Matematica e Applicazioni Universita di Napoli Federico II Complesso Universitario Monte S. Angelo Via Cintia I- 80126 Napoli Italy

A group G is called a PC-group if the factor group G/CG（〈X）^G） is polycyclic for each element x of G. It is proved here that if G is a group of infinite rank whose proper subgroups of infinite rank have the property PC, then G itself is a PC-group, provided that G has an abelian non-trivial homomorphic image. Moreover, under the same assumption, a complete classification of minimal non-PC groups is obtained.

关键词： PC-group minimal non-PC group group of infinite rank

Potential and progress of studying mountain biodiversity by means of butterfly genetics and genomics

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Journal of Genetics and Genomics 2024年第3期51卷 292-301页

作者： Shuting Wang marco Girardello Wei Zhang State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China cE3c-Centre for Ecology Evolution and Environmental Changes/Azorean Biodiversity GroupFaculdade de Ciencias Agrarias e do AmbienteUniversidade dos Açores9700-042 Angra do HeroísmoTerceiraPortugal

Mountains are rich in biodiversity,and butterflies are species-rich and have a good ecological and evolutionary research *** review addresses the potential and progress of studying mountain biodiversity using butterflies as a *** discuss the uniqueness of mountain ecosystems,factors influencing the distribution of mountain butterflies,representative genetic and evolutionary models in butterfly research,and evolutionary studies of mountain biodiversity involving butterfly genetics and ***,we demonstrate the necessity of studying mountain butterflies and propose future *** review provides insights for studying the biodiversity of mountain butterflies as well as a summary of research methods for reference.

关键词： Mountain ecosystem Butterfly Biodiversity Adaptation Genomics Genetics

Multidisciplinary approach for patients with esophageal cancer

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World Journal of Gastroenterology 2012年第46期18卷 6737-6746页

作者： Victoria M Villaflor marco E Allaix Bruce Minsky Fernando A Herbella marco G Patti Department of Medicine Section Hematology/Oncology University of Chicago Medicine Department of Surgery University of Chicago Medicine Radiation Oncology University of Chicago Medicine

Patients with esophageal cancer have a poor prognosis because they often have no symptoms until their disease is advanced. There are no screening recommendations for patients unless they have Barrett's esophagitis or a significant family history of this disease. Often, esophageal cancer is not diagnosed until patients present with dysphagia, odynophagia, anemia or weight loss. When symptoms occur, the stage is often stage Ⅲ or greater. Treatment of patients with very early stage disease is fairly straight forward using only local treatment with surgical resection or endoscopic mucosal resection. The treatment of patients who have locally advanced esophageal cancer is more complex and controversial. Despite multiple trials, treatment recommendations are still unclear due to conflicting data. Sadly, much of our data is difficult to interpret due to many of the trials done have included very heterogeneous groups of patients both histologically as well as anatomically. Additionally, studies have been underpowered or stopped early due to poor accrual. In the United States, concurrent chemoradiotherapy prior to surgical resection has been accepted by many as standard of care in the locally advanced patient. Patients who have metastatic disease are treated palliatively. The aim of this article is to describe the multidisciplinary approach used by an established team at a single high volume center for esophageal cancer, and to review the literature which guides our treatment recommendations.

关键词： Esophageal Cancer Multimodality therapy Multidisciplinary therapy Chemoradiotherapy Esophageal resection Esophagectomy

The identification of wildlife-vehicle collision hotspots: Citizen science reveals spatial and temporal patterns

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Ecological Processes 2021年第1期10卷 99-111页

作者： Francesco Valerio marco Basile Rosario Balestrieri Mediterranean Institute for Agriculture Environment and DevelopmentInstituto de Investigação e Formação AvançadaUniversidade deÉvoraPólo da MitraAp.947006-554ÉvoraPortugal. UBC-Unidade de Biologia da Conservação Departamento de BiologiaUniversidade deÉvoraPólo da MitraAp.947002-554ÉvoraPortugal. Associazione per la Ricerca la Divulgazione e l’Educazione Ambientale–ARDEAVia Ventilabro80126 NapoliItaly. Chair of Wildlife Ecology and Management University of FreiburgTennenbacher Str.479106 FreiburgGermany. Stazione Zoologica Anton Dohrn Villa Comunale 180121 NaplesItaly.

Linear infrastructures(e.g.,roads,railways,pipelines,and powerlines)pose a serious threat to wildlife,due to the risk of wildlife-vehicle collisions(roadkills).The placement of mitigation measures,such as crossing structures,should consider species’life cycles and ecological *** an assessment would require data collection over large areas,which may be possible by employing citizen *** this study,we aimed to identify spatiotemporal trends of roadkill occurrence using citizen science data from one of the most urbanized and biodiversityrich regions of *** trends were analyzed using generalized additive models,while landscape patterns were assessed by identifying significant thresholds over land cover gradients,related to increases in relative roadkill abundance,by employing threshold indicator taxa *** approach recorded a total of 529 roadkills,including 33 different species,comprising 13 mammal,10 bird,6 reptile,and 2 amphibian *** analysis indicated significant temporal trends for the red fox,the European hedgehog,the stone marten and the European badger,with peaks in roadkill occurrence between the winter and spring *** roadkill abundance increased mostly in landscapes with anthropogenic land cover classes,such as complex cultivations,orchards,or urban *** results allowed us to develop a map of potential roadkill risk that could assist in planning the placement of mitigation *** science contributions from highly populated areas allowed data collection over a large area and a dense road network,and also directly led to the evaluation of management decisional options.

关键词： Roadkill Land cover Road ecology Seasonal trend Spatial prioritization Urban wildlife

Evolutionary computing and machine learning for discovering of low-energy defect configurations

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npj Computational Materials 2021年第1期7卷 628-640页

作者： marco Arrigoni Georg K.H.Madsen Institute of Materials Chemistry TU WienViennaAustria

Density functional theory(DFT)has become a standard tool for the study of point defects in ***,finding the most stable defective structures remains a very challenging task as it involves the solution of a multimodal optimization problem with a high-dimensional objective ***,the approaches most commonly used to tackle this problem have been mostly empirical,heuristic,and/or based on domain *** this contribution,we describe an approach for exploring the potential energy surface(PES)based on the covariance matrix adaptation evolution strategy(CMA-ES)and supervised and unsupervised machine learning *** resulting algorithm depends only on a limited set of physically interpretable hyperparameters and the approach offers a systematic way for finding low-energy configurations of isolated point defects in *** demonstrate its applicability on different systems and show its ability to find known low-energy structures and discover additional ones as well.

关键词： function configuration finding

Validation of fluid-particle interaction force relationships in binary-solid suspensions

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Particuology 2015年第6期13卷 40-48页

作者： marco Rotondi Renzo Di Felice Paolo Pagliai Department of Civil Chemical and Environmental Engneering University of Genova Via Opera Pia 15 16145 Genova Italy

In this work several relationships governing solid-fluid dynamic interaction forces were validated against experimental data for a single particle settling in a suspension of other smaller particles. It was observed that force relationships based on Lattice-Boltzmann simulations did not perform as well as other inter- action types tested. Nonetheless, it is apparent that, in the case of a suspension of different particle types, it is important that the correct choice is made as to how the contribution to the overall fluid-particle interaction force is split between buoyancy and drag. Experimental evidence clearly suggests that the ＂generalized＂ Archimedes＇ principle （where the foreign particle is considered to displace the whole suspension and not just the fluid） provides the best result.

关键词： Solid-fluid suspensionsSolid-fluid interaction forcesDrag forceBuoyancy force