检索结果-南通市图书馆

Ubiquitination and PARylation cross-talk about immunity

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2021年第12期14卷 1976-1978页

作者： marco Trujillo Faculty of Biology Cell BiologyⅡUniversity of Freiburg79104 FreiburgGermany

Post-translational modifications(PTMs)allow organisms to quickly respond and acclimate to environmental *** attachment of ubiquitin and its different polymeric forms,act as signals that modulate most aspects of cellular *** is of key importance to maintain protein homeostasis during the immune response by coordinating the major degradation path-ways,namely proteasomal and vacuolar in plants(Trujillo,2021).Poly(ADP-ribosyl)ation(PARylation),has also been linked to various stress responses and shows many commonalities to ubiquitination(Rissel and Peiter,2019).Yao et al.(2021)have now uncovered a link between these two PTMs.

关键词： maintain translational polymeric

Activity-dependent remodeling of genome architecture in engram cells facilitates memory formation and recall

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2022年第5期17卷 991-993页

作者： Asaf marco Neuro-Epigenetics Laboratory the Robert H.Smith Faculty of FoodEnvironment and Agriculturethe Hebrew University of JerusalemRehovol CampusIsrael

The formation and preservation of longterm memories critically depend upon coordinated activity of neuronal circuits,intracellular signaling cascades and synaptic remodeling(Josselyn et al.,2015).These essential proce... 详细信息

关键词： remodeling ngram

Systems approach to underground safety

在线全文

学校读者我要写书评

暂无评论

Underground Space 2020年第3期5卷 258-266页

作者： marco Bettelini Amberg Engineering Ltd. Switzerland

The safety of underground traffic infrastructures can be considered from several viewpoints as a fairly mature *** minimum requirements for road tunnel safety were developed for all European countries in ***,safety is codified in a detailed(at times even too detailed)manner,such as for road tunnels in several *** design can at times be extremely rigid and difficult for adapting to specific conditions,which in some cases may need to be more demanding than a"standard"*** types of underground infrastructure,particularly,rail tunnels and underground industrial facilities,share a number of common safety-related issues with road tunnels,but are generally much less *** example,there is no common regulation for the ventilation of rail tunnels in *** metro systems have different safety standards,in spite of having similar *** present study illustrates selected aspects of a holistic approach required for achieving a high and sustainable safety level in underground *** aspects and differences between the various types of"conventional"and"emerging"underground infrastructure are outlined and the consequences are discussed,such as the different types of threats,widely differing probabilities of occurrence,and widely differing number of persons *** facilities require different safety systems;however,they can rely on common thinking and *** is essential for all stakeholders,ranging from operators and safety officers to fire services and administrative authorities,to grasp commonalities and differences to adapt requirements,regulations,and approaches to their specific needs.

关键词： Safety Underground space Tunnel

Biodegradability of soil water soluble organic carbon extracted from seven different soils

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2009年第5期21卷 641-646页

作者： SCAGLIA barbara ADANI Fabrizio Department of Crop Science Section of Soil Chemistry University of Milano

Water soluble organic carbon （WSOC） is considered the most mobile and reactive soil carbon source and its characterization is an important issue for soil ecology study. A biodegradability test was set up to study WSOC extracted from 7 soils differently managed. WSOC was extracted from soil with water （soil/water ratio of 1：2, W/V） for 30 min, and then tested for biodegradability by a liquid state respirometric test. Result obtained confirmed the finding that WSOC biodegradability depended on the both land use and management practice. These results suggested the biodegradability test as suitable method to characterize WSOC, and provided useful information to soil fertility.

关键词： biodegradability test cumulated oxygen uptake water extractable organic carbon water soluble organic carbon

On the use of Max-SAT and PDDL in RBAC maintenance

在线全文

学校读者我要写书评

暂无评论

Cybersecurity 2018年第1期1卷 592-616页

作者： marco Benedetti marco Mori Bank of Italy ICT DepartmentCentro Donato MenichellaRomaItaly

Role-Based Access Control(RBAC)policies are at the core of Cybersecurity as they ease the enforcement of basic security principles,e.g.,Least Privilege and Separation of *** ICT systems and business processes evolve,RBAC policies have to be updated to prevent unauthorised access to resources by capturing errors and misalignments between the current policy and ***,such update process is a human-intensive activity and it is expected to meet specific *** paper proposes a semi-automatic RBAC maintenance process to fix and refine an RBAC state when“exceptions”and“violations”are *** are permissions some users realise they miss that are instrumental to their job and should be granted as soon as possible,while violations are permissions that have to be revoked since they are no longer required by their current *** propose a formalisation for the maintenance process which fixes single and multiple exceptions and violations by balancing two conflicting objectives,i.e.,(i)optimising the current RBAC state,and(ii)reducing the transition *** approach is based on a Max-SAT formalisation of the constraint-based optimisation problem,and on PDDL planning to define the transition strategy with minimum *** implementation relies on incomplete Max-SAT solvers and satisficing PDDL planners which provide approximations of optimal *** along with a comparative evaluation show good performance on real-world benchmarks.

关键词： RBAC maintenance Max-SAT PDDL planner RBAC evolution

Classical model for diffusion and thermalization of heavy quarks in a hot medium: memory and out-of-equilibrium effects

维普期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2019年第9期43卷 90-100页

作者： marco Ruggieri marco Frasca Santosh Kumar Das School of Nuclear Science and Technology Lanzhou University222 South Tianshui RoadLanzhou 730000China Via Erasmo Gattamelata Rome 00176Italy School of Physical Science Indian Institute of Technology GoaPonda-403401GoaIndia

We consider a simple model for the diffusion of heavy quarks in a hot bath,modeling the latter by an ensemble of oscillators distributed according to either a thermal distribution or to an out-of-equilibrium distribution with a saturation *** this model it is easy to introduce memory effects by changing the distribution of oscillators:we model them by introducing a Gaussian distribution,dN/dω,which can be deformed continuously from aδ?function,giving a Markov dissipation,to a broad kernel with *** the equation of motion of the heavy quark in the bath,we remark how dissipation comes out naturally as an effect of the back-reaction of the oscillators on the ***,the exact solution of this equation allows to define the thermalization time as the time necessary to remove any memory of the initial *** find that the broadening of the dissipative kernel,while keeping the coupling fixed,lowers the thermalization *** also derive the fluctuation-dissipation theorem for the bath,and use it to estimate the kinematic regime in which momentum diffusion of the heavy quark dominates over *** find that diffusion is more important as long as K0/E is small,where K0 and E denote the initial energy of the heavy quark and the average energy of the bath,respectively.

关键词： relativistic heavy ion collisions heavy quarks Brownian motion memory effect quark-gluon plasma

Topology Search of 3-DOF Translational Parallel Manipulators with Three Identical Limbs for Leg Mechanisms

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2015年第4期28卷 666-675页

作者： WANG Mingfeng CECCARELLI marco LARM:Laboratory of Robotics and Mechatronics University of Cassino and South Latium

Three-degree of freedom（3-DOF） translational parallel manipulators（TPMs） have been widely studied both in industry and academia in the past decades. However, most architectures of 3-DOF TPMs are created mainly on designers＇ intuition, empirical knowledge, or associative reasoning and the topology synthesis researches of 3-DOF TPMs are still limited. In order to find out the atlas of designs for 3-DOF TPMs, a topology search is presented for enumeration of 3-DOF TPMs whose limbs can be modeled as 5-DOF serial chains. The proposed topology search of 3-DOF TPMs is aimed to overcome the sensitivities of the design solution of a 3-DOF TPM for a LARM leg mechanism in a biped robot. The topology search, which is based on the concept of generation and specialization in graph theory, is reported as a step-by-step procedure with desired specifications, principle and rules of generalization, design requirements and constraints, and algorithm of number synthesis. In order to obtain new feasible designs for a chosen example and to limit the search domain under general considerations, one topological generalized kinematic chain is chosen to be specialized. An atlas of new feasible designs is obtained and analyzed for a specific solution as leg mechanisms. The proposed methodology provides a topology search for 3-DOF TPMs for leg mechanisms, but it can be also expanded for other applications and tasks.

关键词： topology search 3-DOF translational parallel manipulators(TPMs) creative design leg mechanisms

Design issues for human-machine platform interface in cable-based parallel manipulators for physiotherapy applications

在线全文

学校读者我要写书评

暂无评论

Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第4期11卷 231-239页

作者： marco CECCARELLI Lotfi ROMDHANE Laboratory of Robotics and Mechatronics DIMSATUniversity of Cassino-CassinoItaly Département de Mécanique Avancée Ecole Nationale d'Ingénieurs de SousseTunisia

We outline problems and potential solutions for feasible human-machine interfaces using cable-based parallel manipulators for physiotherapy *** an engineering perspective,we discuss the design constraints related to acceptance by patients and physiotherapist *** date,most designs have focused on mobile platforms that are designed to be operated as an end-effector connected to human limbs for direct patient *** specific examples are illustrated from the authors' experience with prototypes available at Laboratory of Robotics and Mechatronics (LARM),Italy.

关键词： Robot design Robot applications Cable-based parallel manipulators Human-machine mechanical interfaces

Experimental Characterization of Operation of a Waist-Trunk System with Parallel Manipulators

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2011年第5期24卷 713-722页

作者： CECCARELLI marco CARBONE Giuseppe Laboratory of Robotics and Mechatronics (LARM) University of Cassino

An extensive research activity has been focused on the upper and lower limbs of humanoid robots. However, due to mechanical design difficulties and complex control of multi-body system, the torso of humanoid robot is somehow a neglected or simplified design part. In this paper, operation performance of a new waist-trunk system as torso for humanoid robots is presented through results of lab experimental tests. The proposed waist-trunk system is composed of two 3 DOFs （degrees of freedom） parallel manipulators, which are connected in a serial chain architecture. A prototype is built by using two prototypes of CaPaMan （Cassino Parallel Manipulator）, which are convenient stiff architectures with easy-operation characteristics. Experimental tests are carried out with the aims to imitate lateral-bending and transverse-rotation movements of human torso. Operation performances like displacements, accelerations, and actuation torque are measured for a performance evaluation and design characterization of the used manipulator solution imitating human torso. Experimental test results are illustrated and discussed to show the practical operation feasibility of the proposed architecture and the operation characteristics of the built prototype.

关键词： humanoid robots waist-trunk system parallel manipulators experimental robotics