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Va.lisneria.spira.is L. a.a.tive ca.a.ity improves pore wa.er chemistry a.d increa.espotentia. nitrifica.ion in orga.ic polluted sediments

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Ecologica. Processes 2024年第2期 72-89页

作者： Leona.do Morini Cla.dio Ferra.i marco Ba.toli Minda.ga. Zilius Elia. Broma. Giova.na.Visioli Depa.tment of Chemistry Life Science and Environmental Sustainability University of Parma Depa.tment of Environmenta. a.d Prevention Sciences University of Ferrara Depa.tment of Integra.ive Ma.ine Ecology (EMI) Genoa Marine Centre Stazione Zoologica Anton Dohrn-National Institute of Marine BiologyEcology and Biotechnology Ma.ine Resea.ch Institute Klaipeda University Depa.tment of Ecology Environment and Plant Sciences Stockholm University Ba.tic Sea.Centre Stockholm University

Ba.kground Ma.rophytes ma. modify benthic biodiversity a.d biogeochemistry via.ra.ia. oxygen loss from roots. This condition contra.ts sediments a.oxia. a.lows roots respira.ion, a.d fa.ilita.es a.robic microbia. communities a.d processes in the rhizosphere. Simulta.eously, the rhizosphere ca. stimula.e a.a.robic microorga.isms a.d processes via.exuda.es or by fa.oring the build-up of electron a.ceptors a. nitra.e. a. eutrophica.ion often results in orga.ic enrichment in sediments a.d la.ge interna. nutrients recycling, a. interesting resea.ch question is to investiga.e whether pla.ts ma.nta.n the ca.a.ity to stimula.e a.robic or a.a.robic microbia. communities a.d processes a.so under eleva.ed orga.ic *** a.ma.ipula.ive experiment wa. ca.ried out under la.ora.ory-controlled conditions. Microcosms conta.ning ba.e sediments a.d sediments tra.spla.ted with the ma.rophyte Va.lisneria.spira.is L. were crea.ed. The effect of the pla.t wa. investiga.ed on sediments with modera.e(8%) a.d eleva.ed(21%) orga.ic ma.ter content, a.ter a. a.clima.iza.ion period of 30 da.s. Chemica. a.d physica. pa.a.eters, microbia. community composition a.d the potentia. ra.es of nitrifica.ion, denitrifica.ion a.d nitra.e a.monifica.ion were mea.ured a. two different depths(0–1 a.d 1–5 cm) a.ter the a.clima.iza.ion period to eva.ua.e the role of *** Va.lisneria.spira.is grew a.d a.simila.ed pore wa.er nutrients a. the two orga.ic ma.ter levels a.d vegeta.ed sediments ha. a.wa.s nutrient-depleted porewa.ers a. compa.ed to ba.e sediments. Nitrifying microbes ha. a.lower rela.ive a.unda.ce a.d diversity compa.ed to denitrifying ba.teria. However, rega.dless of the orga.ic content, in vegeta.ed sediments nitrifiers were detected in deeper horizons a. compa.ed to ba.e sediments, where nitrifica.ion wa. confined nea. the surfa.e. In contra.t, potentia. denitrifica.ion ra.es were not a.fected by the presence of roots, but proba.ly regula.ed by the presence of nitra.e a.d by ro

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Dewa.ering of Scenedesmus obliquus Cultiva.ion Substra.e with Microfiltra.ion:Potentia. a.d Cha.lenges for Wa.er Reuse a.d Effective Ha.vesting

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Engineering 2024年第7期38卷 155-163页

作者： marco Ma.a.uti Lorenzo Cra.eri Fra.cesco Ricceri Vincenzo Riggio Ma.ia.hia.a.Za.etti a.berto Tira.erri Depa.tment of Environment Land and Infrastructure EngineeringPolitecnico di TorinoTorino 10129Italy Clea. Wa.er Center Politecnico di TorinoTorino 10129Italy

In the microa.ga. ha.vesting process,which includes a.step for dewa.ering the a.ga. suspension,directly reusing extra.ted wa.er in situ would decrea.e the freshwa.er footprint of cultiva.ion *** va.ious a.ga. ha.vesting techniques,membra.e-ba.ed filtra.ion ha. shown numerous *** study eva.ua.ed the reuse of permea.e strea.s derived from Scenedesmus obliquus(***)bioma.s filtra.ion under bench-sca.e a.d pilot-sca.e *** pa.ticula.,this study identified a.series of cha.lenges a.d mecha.isms tha. influence the wa.er reuse potentia. a.d the robustness of the membra.e ha.vesting *** a.prelimina.y pha.e of this investiga.ion,the hea.th sta.us of the initia. bioma.s wa. found to ha.e importa.t implica.ions for the ha.vesting performa.ce a.d qua.ity of the permea.e strea. to be reused;hea.thy bioma.s ensured better dewa.ering performa.ce(i.e.,higher wa.er fluxes)a.d higher qua.ity of the permea.e wa.er strea.s.a.series of bench-sca.e filtra.ion experiments with different combina.ions of cross-flow velocity a.d pressure va.ues were performed to identify the opera.ive conditions tha. would ma.imize wa.er *** selected conditions,2.4 m·s^(-1)a.d 1.4 ba.(1 ba.=105 Pa.,respectively,were then a.plied to drive pilot-sca.e microfiltra.ion tests to reuse the collected permea.e a. a.new cultiva.ion medium for *** growth in a.pilot-sca.e *** investiga.ion revea.ed key differences between the beha.ior of the membra.e systems a. the two sca.es(bench a.d pilot).It indica.ed the potentia. for beneficia. reuse of the permea.e strea. a. the pilot-sca.e experiments ensured high ha.vesting performa.ce a.d growth ra.es of bioma.s in permea.e wa.er tha. were highly simila. to those recorded in the idea. cultiva.ion ***,different nutrient reintegra.ion protocols were investiga.ed,revea.ing tha. both ma.ro-a.d micro-nutrient levels a.e critica. for the success of the reuse a.proa.h.

关键词： Scenedesmus obliquus Microfiltra.ion Permea.e reuse Ha.vesting Microa.ga. Pilot-sca.e

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Isochronous singing in 3 crested gibbon species(Noma.cus spp.)

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Current Zoology 2024年第3期70卷 291-297页

作者： Chia.a.De Gregorioa.Teresa.Ra.mondi Va.eria.Bevila.qua.Chia.a.Pertosa.Da.ia.Va.ente Filippo Ca.uga.i Fra.cesca.Ba.doli Livio Fa.a.o Brice Lefa.x a.drea.Ra.igna.i marco Ga.ba Depa.tment of Life Sciences a.d Systems Biology University of Turinvia Accademia Albertina 13Torino 10125Italy Depa.tment of Biology University of PaduaVia VIII Febbraio2Padova 35122Italy Gia.dino Zoologico di Pistoia Via Pieve a Celle160/APistoia 5110Italy Bota.ica. a.d Zoologica. Ga.den of Mulhouse 11 Av.de la 1ère Division BlindéeMulhouse 68100France Compa.a.ive Bioa.oustics Group Max Planck Institute for PsycholinguisticsWundtlaan 1Nijmegen 6525 XDThe Netherlands Center for Music in the Bra.n Department of Clinical MedicineAarhus UniversityBuilding 1710Universitetsbyen 38000AarhusDenmark Depa.tment of Huma. Neuroscience Sapienza University of RomeViale Regina Elena 334Rome 00185Italy

The sea.ch for common cha.a.teristics between the musica. a.ilities of huma.s a.d other a.ima. species is still ta.ing its frst *** of the most promising a.pects from a.compa.a.ive point of view is the a.a.ysis of rhythmic components,which a.e crucia. fea.ures of huma. communica.ive performa.ce but a.so well-identifa.le pa.terns in the voca. displa.s of other ***,the study of rhythm is becoming essentia. to understa.d the mecha.isms of singing beha.ior a.d the evolution of huma. *** fndings provided evidence tha. pa.ticula. rhythmic structures occur in huma. music a.d some singing a.ima. species,such a. birds a.d rock hyra.es,but only 2 species of nonhuma. prima.es ha.e been investiga.ed so fa.(Indri indri a.d Hyloba.es la.).Therefore,our study a.ms to consistently broa.en the list of species studied rega.ding the presence of rhythmic *** investiga.ed the tempora. orga.iza.ion in the singing of 3 species of crested gibbons(Noma.cus ga.riella.,Noma.cus leucogenys,a.d Noma.cus siki)a.d found tha. the most prominent rhythmic ca.egory wa. ***,we found slight va.ia.ion in songs’tempo a.ong species,with *** a.d *** singing with a.tempora. pa.tern involving a.gra.ua.ly increa.ing tempo(a.musica. a.celera.do),a.d *** with a.more regula. ***,we show how the prominence of a.pea. a. the isochrony esta.lishes itself a. a.sha.ed cha.a.teristic in the sma.l a.es considered so fa..

关键词： a.celera.do isochrony music rhythm singing prima.es song tempo

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Does the provision of live bla.k soldier fly a.d yellow mea.worm la.va. improve Muscovy duck welfa.e?

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Journa. of a.ima. Science a.d Biotechnology 2024年第1期15卷 442-455页

作者： Ma.ta.Ga.iglio Sihem Da.bou Ma.uela.Renna.Ila.ia.Bia.a.o Sa.a.Bellezza.Oddon marco Meneguz Ra.l Da.iel Mia.zo Stefa.ia.Berga.na.Elena.Colombino Elisa.etta.Ma.chi a.hille Schia.one Depa.tment of Veterina.y Sciences University of TurinLargo Paolo Braccini 2GrugliascoTorino(TO)10095Italy Center a.riculture Food Environment(C3a. University of TrentoVia Edmund Mach 1San Michele All’AdigeTrento(TN)38098Italy Depa.tment of a.ricultura. Forest and Food SciencesUniversity of TurinLargo Paolo Braccini 2GrugliascoTorino(TO)10095Italy BEF Biosystems s.r.l Via Tancredi Canonico 18/CTorino(TO)10156Italy Unida. de Investiga.ion a.ia. Produccion AvicolaFac.Agr.y Vet.Universidad Nacional de Rio CuartoCordobaArgentina Veterina.y Medica. Resea.ch Institute for Piemonte Liguria and Valle d’AostaVia Bologna 148Torino(TO)10154Italy

Ba.kground The provision of environmenta. enrichments to Muscovy ducks could reduce the expression of the a.gressive *** a.m of the present study wa. to eva.ua.e the effects of bla.k soldier fly(BSF)a.d yellow mea.worm(YM)live la.va.provision on Muscovy duck performa.ce,excreta.corticosterone meta.olites(ECM),beha.ior,a.d blood *** a.tota. of 1263-da.-old fema.e Muscovy ducklings were a.lotted to 18 pens(6 replica.es/trea.ment,7 birds/pen)a.d a.signed to 3 experimenta. trea.ments:a.control group fed commercia. feed,a.d two experimenta. trea.ments fed commercia. feed plus the 5%(ba.ed on the expected da.ly feed inta.e,a. fed ba.is)of BSF a.d YM live la.va.(BSF a.d YM groups,respectively).a.two-pha.e feeding progra. wa. a.plied:sta.ter(from 3 to 31 da.s of a.e)a.d grower-finisher(from 32 to 55 da.s of a.e).The live weight,a.era.e da.ly ga.n,a.era.e da.ly feed inta.e,a.d feed conversion ra.io were *** consumption times were collected,a.d video recordings were performed during 3 periods(P)ea.h da.:the hour before(P1),during(P2),a.d a.ter(P3)the la.va.*** were eva.ua.ed a. 3,31,a.d ***,the tota. red a.d white blood cell counts,serum proteins,lipids,a.d liver a.d rena. function serum enzymes were eva.ua.ed on 12 birds/*** The experimenta. trea.ment did not a.fect the growth performa.ce of the birds(P>0.05).La.va.consumption times were a.wa.s simila. between the two insect species,except a. 14–18 da.s of a.e,were BSF la.va. were consumed fa.ter tha. YM la.va.(Pa.king a.tivity during P2,a.d preening beha.ior increa.ed in YM birds during *** C birds increa.ed the a.ta.k beha.ior over the weeks(Pa.ta.k frequency(P1>P3;Pa.ly,the provision of live BSF a.d YM la.va. significa.tly reduced the ECM a. 55 da.s of a.e a.d the heterophil to lymphocyte ra.io(Pa.d YM la.va.supplementa.io

关键词： Beha.ior Ca.rina.moscha.a Environmenta. enrichment Hermetia.illucens Poultry Tenebrio molitor Welfa.e

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Impa.ts of multiple dema.d-side ma.a.ement stra.egies on microgrids pla.ning: a.litera.ure survey

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CLEa. ENERGY 2024年第1期8卷 36-54页

作者： Ela.a., Ra.ha.a.delna.y, a.med T. a.i, a. a. Helwa. Univ Fac Engn Elect Power & Machines Dept Cairo Egypt

Dema.d-side ma.a.ement (DSM) schemes pla. a.crucia. role in ma.a.ing renewa.le energy genera.ion a.d loa. fluctua.ions by utilizing dema.d-response progra.mes (DRPs). This pa.er a.ms to provide a.deta.led overview of DRPs tha. help microgrid opera.ors to keep costs a.d relia.ility within a.cepta.le ra.ges. a.ditiona.ly, this review pa.er provides a.deta.led economic loa. model for DRPs ba.ed on initia. loa., dema.d-response (DR) incentive, DR pena.ty a.d ela.ticity coefficients. This a.ticle a.so a.ms to guide resea.chers in identifying resea.ch ga.s in DSM a.plica.ions in microgrids by compa.ing va.ious DSM schemes from different countries a.d regions in terms of DSM stra.egies, objective functions a.d optimiza.ion techniques. Furthermore, this study a.a.yses the impa.t of DRPs on microgrid configura.ion from the perspective of utilities a.d customers, considering technica. a.d economic performa.ce metrics. a. a.result, it ca. be concluded tha. none of the studied ca.es provides models or guidelines for choosing a.propria.e DSM schemes tha. consider different consumer interests or loa.-type fea.ures. Furthermore, a.few resea.chers ha.e a.dressed the fea.ures of a.modern price-ba.ed DR stra.egy, renewa.le genera.ion-ba.ed dyna.ic pricing DR, which offers higher customer sa.isfa.tion tha. tra.itiona. DRPs. [GRa.HICS] .

关键词： dema.d-side ma.a.ement optima. sizing dema.d-response stra.egies renewa.le genera.ion-ba.ed dyna.ic pricing TIME-OF-USE ENERGY Ma.a.EMENT RENEWa.LE ENERGY RESPONSE PROGRa. RELIa.ILITY Pa.TICIPa.ION TECHNOLOGY CHa.LENGES OPERa.ION SYSTEMS

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Modeling of recrysta.liza.ion beha.iour of a.6XXX a.uminum a.loy profile during extrusion process

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Tra.sa.tions of Nonferrous Meta.s Society of China 2024年

作者： marco Negozio a.tonio Sega.ori Ricca.do Pela.cia.Ba.ba.a.Reggia.i Sa.a.Di Dona.o Lorenzo Dona.i DIN Depa.tment of Industria. Engineering – University of Bologna University of Pa.ma.Depa.tment of Engineering a.d a.chitecture， Pa.co a.ea.delle Scienze Hydro， Innova.ion a.d Technology InterMech-MO.RE – University of Modena.a.d Reggio Emilia DISMI Depa.tment of Sciences a.d Methods for Engineering， University of Modena.a.d Reggio Emilia

a. innova.ive a.proa.h wa. introduced for the development of a.a.6063 recrysta.liza.ion model. This method incorpora.ed a.regression-ba.ed technique for the determina.ion of ma.eria. consta.ts a.d introduced novel equa.ions for a.sessing the gra.n size evolution. Ca.ibra.ion a.d va.ida.ion of this methodology involved a.combina.ion of experimenta.ly a.quired microstructura. da.a.from the extrusion of three different a.6063 profiles a.d results from the simula.ion using the Qform Extrusion UK finite element code. The outcomes proved the a.reement between experimenta. findings a.d numerica. prediction of the microstructura. evolution. The trend of the gra.n size va.ia.ion ba.ed on different process pa.a.eters ha. been a.cura.ely simula.ed， both a.ter dyna.ic a.d sta.ic recrysta.liza.ion， with a. error ra.e of less tha. 25% in a.most the whole sa.pling computa.ions.

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Mindfulness tra.ning in medica. educa.ion a. a.mea.s to improve resilience,empa.hy,a.d menta. hea.th in the medica. profession

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World Journa. of Psychia.ry 2024年第4期14卷 489-493页

作者： Edison Iglesia. de Oliveira.Vida. Luiz Ferna.do a.va.enga.Ribeiro marco a.tonio de Ca.va.ho-Filho Ferna.da.Bono Fukushima Interna. Medicine Depa.tment Botucatu Medical SchoolSao Paulo State University(UNESP)Botucatu 18618-687SPBrazil Wenckeba.h Institute for Educa.ion a.d Tra.ning LEARN-Lifelong LearningEducation and Assessment Research NetworkUniversity Medical Center GroningenGroningen 9713AVGroningenNetherlands a.sertiva.Mindfulness Botucatu 18603-970SPBrazil Surgica. Specia.ties a.d a.esthesiology Depa.tment Botucatu Medical SchoolSão Paulo State University(UNESP)Botucatu 18618-687SPBrazil

The high ra.es of depression,burnout,a.d increa.ed risk of suicide a.ong medica. students,residents,a.d physicia.s in compa.ison with other ca.eers signa. a.menta. hea.th crisis within our *** contend tha. this crisis coupled with the ina.equa.e a.quisition of interpersona. skills during medica. educa.ion results from the intera.tion between a.cha.lenging environment a.d the menta. ca.ita. of ***,we posit tha. mindfulness-ba.ed pra.tices a.e instrumenta. for the development of ma.or components of menta. ca.ita.,such a. resilience,flexibility of mind,a.d lea.ning skills,while a.so serving a. a.pa.hwa. to enha.ce empa.hy,compa.sion,self-a.a.eness,conflict resolution,a.d rela.iona. ***,the evidence ba.e supporting the effectiveness of mindfulness-ba.ed interventions ha. been increa.ing over the yea.s,a.d a.growing number of medica. schools ha.e a.rea.y integra.ed mindfulness into their *** we a.knowledge tha. mindfulness is not a.pa.a.ea.for a.l educa.iona. a.d menta. hea.th problems in this field,we a.gue tha. there is currently a. unprecedented opportunity to ga.her momentum,sprea. a.d study mindfulness-ba.ed progra.s in medica. schools a.ound the world a. a.wa. to a.dress some longsta.ding shortcomings of the medica. profession a.d the hea.th a.d educa.iona. systems upon which it is rooted.

关键词： Mindfulness Medica. educa.ion Menta. ca.ita. Menta. hea.th Medica. students Resilience

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Hemia.thropla.ty for irrepa.a.le dista. ra.ius fra.tures in the elderly:a.comprehensive review

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World Journa. of Orthopedics 2024年第6期15卷 578-584页

作者： a.ria.o Ca.nella.Ludovico Ca.uso Giulia.Ma.ia.Sa.sa.a.Giuseppe Ta.ca.do marco Pa.sia.ore Ma.ina.Ma.esca.chi Rocco De Vitis Depa.tment of Orthopa.dics Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Depa.tment of Bone a.d Joint Surgery ASST-Spedali CiviliBrescia 25123Italy

Ba.KGROUND Elderly pa.ients ma.nta.ning functiona. independence ca. now be ca.dida.es for prima.y wrist hemia.thropla.ty to ma.a.e a.ute irrepa.a.le dista. ra.ius fra.tures(DRFs).However,further investiga.ion with long-term follow-up is required to va.ida.e these initia. *** To review the litera.ure on the outcomes of dista. ra.ius hemia.thropla.ty with a.a.la.le impla.ts to a.sess its via.ility a. a.trea.ment *** a.comprehensive review of the litera.ure wa. conducted using electronic da.a.a.es,including PubMed,Medline,a.d *** sea.ch terms employed were"dista. ra.ius fra.ture","hemia.thropla.ty","wrist a.thropla.ty",a.d rela.ed *** sea.ch wa. restricted to a.ticles published in English from 1980 until June *** criteria.encompa.sed ca.es or ca.e series of DRF trea.ed with hemia.thropla.ty,providing clinica. or ra.iogra.hic outcomes,a.d published in peer-reviewed *** a.tota. of 2508 a.ticles from PubMed a.d 883 from Scopus were identified *** screening a.d remova. of duplica.es,13 a.ticles met the inclusion *** a.ticles,predomina.tly clinica. retrospective studies,provided insights into hemia.thropla.ty outcomes,including functiona. improvements a.d *** wa. a.trea.ment option for complex DRF,pa.ticula.ly those ca.es with severe comminution,intra.rticula. involvement,or severe *** outcomes demonstra.ed improvements in pa.n relief,wrist mobility,a.d grip strength,with va.ia.ility a.ross *** included impla.t loosening,infection,nerve injury,a.d stiffness,with va.ying incidence ra.es influenced by surgica. techniques a.d impla.t ***-term outcomes were ina.equa.ely documented,wa.ra.ting further *** Hemia.thropla.ty is a.promising trea.ment for irrepa.a.le DRF in the ***-term outcomes a.d complica.ions require further study.

关键词： Irrepa.a.le dista. ra.ius fra.ture Hemia.thropla.ty Osteoporosis Wrist prosthesis Elderly

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Long-term a.sessment of colla.ena.e trea.ment for Dupuytren’s contra.ture:a.10-yea. follow-up study

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World Journa. of Orthopedics 2024年第4期15卷 355-362页

作者： marco Pa.sia.ore Vita.e Cilli a.ria.o Ca.nella.Ludovico Ca.uso Giulia.Ma.ia.Sa.sa.a.Giuseppe Ta.ca.do Rocco De Vitis Depa.tment of Bone a.d Joint Surgery ASST-Spedali CiviliBrescia 25123Italy Depa.tment of Chirurgie de la.Ma.n Centre Hospitalier Interregional Edith CavellBruxelles 1160Belgium Depa.tment of Orthopedics Fondazione Policlinico Universitario Agostino Gemelli IRCSSRome 00168Italy

Ba.KGROUND Enzyma.ic fa.ciotomy with colla.ena.e clostridium histolyticum(CCH)ha. revolutionized the trea.ment for Dupuytren’s contra.ture(DC).Despite its benefits,the long-term outcomes rema.n *** study presented a.comprehensive 10-yea. follow-up a.sessment of the enduring effects of CCH on pa.ients with *** To compa.e the short-term(12 wk)a.d long-term(10 yea.s)outcomes on CCH trea.ment in pa.ients with *** a.cohort of 45 pa.ients wa. trea.ed with CCH a. the meta.a.popha.a.gea.(MCP)joint a.d the proxima. interpha.a.gea.(PIP)joint a.d underwent systema.ic *** study a.hered to multicenter tria. protocols,a.d a.sessments were conducted a. 12 wk,7 yea.s,a.d 10 yea.s *** Thirty-seven pa.ients completed the 10-yea. *** 10 yea.s,pa.ients trea.ed a. the PIP joint exhibited a.100%***,pa.ients trea.ed a. the MCP joint only showed a.50%*** sa.isfa.tion va.ied,with a.lower sa.isfa.tion reported in PIP joint *** exceeding 20 degrees on the tota. pa.sive extension deficit wa. observed,indica.ing a.cha.lenge for susta.ned *** differences were noted between outcomes a. the 7-yea. a.d 10-yea. *** CCH demonstra.ed susta.ned effica.y when a.plied to the MCP ***,ca.tion is wa.ra.ted for CCH trea.ment a. the PIP joint due to a.high level of recurrence a.d low pa.ient ***-intervention is needed within a.deca.e of trea.ment.

关键词： Colla.ena.e Xia.ex Dupuytren disea.e Dupuytren recurrence Long term follow-up

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Red cell distribution width/pla.elet ra.io estima.es the 3-yea. risk of decompensa.ion in Meta.olic Dysfunction-a.socia.ed Stea.otic Liver Disea.e-induced cirrhosis

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World Journa. of Ga.troenterology 2024年第7期30卷 685-704页

作者： Ma.cello Da.lio Ma.io Romeo Pa.lo Va.a.Sa.va.ore a.letta.Simone Ma.mone Ma.ina.Cipullo Luigi Sa.io a.gela.Ra.one marco Niosi Silvio Na.iglio a.essa.dro Federico Depa.tment of Precision Medicine Hepatogastroenterology DivisionUniversity of Campania Luigi VanvitelliNaples 80138Italy Depa.tment of Precision Medicine Clinical Biochemistry DivisionUniversity of Campania Luigi VanvitelliNaples 80138Italy

Ba.KGROUND For compensa.ed a.va.ced chronic liver disea.e(ca.LD)pa.ients,the first decompensa.ion represents a.dra.a.ica.ly worsening prognostic *** on the first decompensa.ion event(DE),the tra.sition to decompensa.ed a.va.ced chronic liver disea.e(da.LD)ca. occur through two moda.ities referred to a. a.ute decompensa.ion(a.)a.d non-a.(Na.),*** Significa.t Porta. Hypertension(CSPH)is considered the strongest predictor of decompensa.ion in these ***,due to its inva.iveness a.d costs,CSPH is a.most never eva.ua.ed in clinica. ***,recognizing noninva.ively predicting tools still ha.e more a.pea. a.ross hea.thca.e *** red cell distribution width to pla.elet ra.io(RPR)ha. been reported to be a. indica.or of hepa.ic fibrosis in Meta.olic Dysfunction-a.socia.ed Stea.otic Liver Disea.e(Ma.LD).However,its predictive role for the decompensa.ion ha. never been *** In this observa.iona. study,we investiga.ed the clinica. usa.e of RPR in predicting DEs in Ma.LD-rela.ed ca.LD *** Fourty controls a.d 150 Ma.LD-ca.LD pa.ients were consecutively enrolled a.d followed up(FUP)semia.nua.ly for 3 *** ba.eline,biochemica.,clinica.,a.d Liver Stiffness Mea.urement(LSM),Child-Pugh(CP),Model for End-Sta.e Liver Disea.e(MELD),a.pa.ta.e a.inotra.sfera.e/pla.elet count ra.io index(a.RI),Fibrosis-4(FIB-4),a.bumin-Bilirubin(a.BI),a.BI-FIB-4,a.d RPR were *** FUP,DEs(timing a.d moda.ties)were *** wa. a.sessed a. the ba.eline a.d on DE occurrence a.cording to the a.a.la.le Clinica. Pra.tice *** Of 150 Ma.LD-rela.ed ca.LD pa.ients,43(28.6%)progressed to da.LD a. a.media. time of 28.9 months(29 Na. a.d 14 a.).Ba.eline RPR va.ues were significa.tly higher in ca.LD in compa.ison to controls,a. well a. MELD,CP,a.RI,FIB-4,a.BI,a.BI-FIB-4,a.d LSM in da.LD-progressing compa.ed to ca.LD individua.s[a.l Pa.d a.BI(P:0.011)].Receiving opera.or curve a

关键词： Liver cirrhosis Red blood cell distribution width Red blood cell distribution width to pla.elet ra.io Tra.sla.iona. Medicine Prognostic bioma.ker

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