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Increa.ed CO2 Levels during the First Ha.f of Incuba.ion a. High a.titude Modifies Embryonic Development of Fertile Leghorn Breeder Eggs

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Food a.d Nutrition Sciences 2024年第7期15卷 524-547页

作者： marco a. juárez-estrada Erik I. López-Ruiz Sonia.López-Cordova.Guillermo Tellez-Isa.a. Oma. F. Pra.o-Rebolledo Depa.ta.ento de Medicina.y Zootecnia.de a.es Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Autnoma de Mxico Ciudad de Mxico Mxico Depa.tment of Poultry Science Division of Agriculture University of Arkansas Fayetteville USA Fa.ulta. de Medicina.Veterina.ia.y Zootecnia Universidad de Colima Tecomn Mxico

The excha.ge of oxygen (O2) a.d ca.bon dioxide (CO2) within a. incuba.or ha. a.significa.t impa.t on embryonic development (ED) a.d ha.ching processes. This study exa.ines the influence of non-ventila.ion (NV) conditions during the first ten da.s of incuba.ion a. high a.titudes on Leghorn hens ha.ching eggs. Five hundred four ha.ching eggs were equa.ly divided into three trea.ment groups a.d pla.ed in twelve incuba.ors (R = 4). The first group wa. subjected to sta.da.d ventila.ed conditions (V) during the setting pha.e. The ventila.ion inlet holes of the rema.ning incuba.ors in the NV trea.ments were closed with either micropore (M) or polypropylene (P) ta.e, referred to a. NVM a.d NVP groups, respectively. These two different a.rtight settings were intended to a.low for a.gra.ua. rise in CO2 na.ura.ly genera.ed by the embryos. Results indica.e tha. ca.bon dioxide concentra.ion gra.ua.ly increa.ed during the first ha.f of incuba.ion, rea.hing 1.42% in the NVM group a.d 1.20% in the NVP group, while the V condition group rema.ned a. 0.15%. From 10 da.s of incuba.ion onwa.ds, norma. V conditions were restored in a.l incuba.ors. The highest ha.cha.ility of fertile eggs (HFE) wa. shown by the NVP group (55.7%), followed by the V (52.6%) a.d NVM (38.6%) groups. The NVP group showed a.grea.er yolk-free body ma.s (YFBM) from 10 da.s of incuba.ion until the ha.ch ba.ket tra.sfer. NV conditions during the first 10 da.s of incuba.ion a. high a.titude produced higher YFBM with gra.ua.ly decrea.ing yolk sa. ma.s. In compa.ison to the NVM a.d V conditions, the pa.ticula. NVP condition showed a.beneficia. impa.t on the qua.ity of ha.ched chicks. Susta.ning NVP condition (1.2% of CO2) throughout the first ha.f of incuba.ion a. high a.titude genera.ed the optima. environment in the incuba.or ensuring the best ha.cha.ility results. This study highlights how importa.t it is for ha.chery ma.a.ers to recognize the influence of low O2 a.d high levels of CO2 on the development tra.ectori

关键词： Non-Ventila.ion Hyperca.nia Hypoxia Egg Ma.s Loss Ha.cha.ility Embryonic Morta.ity Ha.chling Chick Qua.ity

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Correla.ion between Intestina. Hea.th a.d Coccidiosis Preva.ence in Broilers during Different Sea.ons of the Yea. in Bra.il from 2012 to 2018

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Food a.d Nutrition Sciences 2024年第3期15卷 179-198页

作者： Fa.io Luis Ga.oni Ga.riela.Miotto Ga.li Ma.cel Ma.ente Boia.o Lenita.Moura.Stefa.i a.ine Za.pa. marco a. juárez-estrada Guillermo Tellez-Isa.a. a.eksa.dro S. da.Silva a.ima. Hea.th a.d Reproduction Veterinary Medicine Graduate Program Federal University of Santa Maria (UFSM) Santa Maria Brazil a.ima. Science Gra.ua.e Progra. Federal University of Rio Grande do Sul (UFRGS) Porto Alegre Brazil a.ima. Science Gra.ua.e Progra. Santa Catarina State University (UDESC) Chapecó Brazil Depa.ta.ento de Medicina.y Zootecnia.de a.es Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Autonoma de Mexico Ciudad Universitaria Ciudad de Mexico Mexico Depa.tment of Poultry Science Division of Agriculture University of Arkansas Fayetteville AR USA

Coccidiosis is a.disea.e ca.sed by intra.ellula. protozoa. pa.a.ites, specifica.ly belonging to the genus Eimeria. These pa.a.ites ta.get the ga.trointestina. tra.t in different types of hosts, ca.sing sores in the intestina. lining. The presence of these lesions reduces the a.ima.’s a.ility to digest a.d a.sorb nutrients, significa.tly impa.ting their overa.l performa.ce. The current study a.med to explore the potentia. correla.ion between sea.ona. va.ia.ions a.d the incidence of Eimeria.spp-induced lesions in broiler chickens’ ga.trointestina. tra.ts in Bra.il from 2012 to 2018. a.tota. of 8,607 broiler chickens, a.ed 14 to 42 da.s, were sa.pled from 103 poultry integra.ed compa.ies in Bra.il to conduct intestina. hea.th exa.ina.ions. The sa.pling process involved selecting 3 to 6 chickens from ea.h poultry house for exa.ina.ion. The a.sessment included va.ious a.norma.ities such a. shedding of intestina. cells a.d excessive fluid a.d mucus presence, thickening a.d tension of the intestines, food movement, roughened mucosa. surfa.e resembling a.Turkish towel in the sma.l intestine, tissue dea.h, duodena. infla.ma.ion, intestina. infla.ma.ion, gizza.d erosion, presence of worms a.d bedding ma.eria., a.d ingestion of mea.worms. During the sea.ons, winter exhibited the highest a.era.e occurrence of Eimeria.ma.ima.microorga.isms a. 52.83%, with E. a.ervulina.following closely a. 26.42% in second pla.e. In spring, E. ma.ima.ha. a. occurrence of 11.31%, while in fa.l, E. tenella.ha. the lowest occurrence a. 6.74%. When a.a.yzing the sea.ona. occurrence of Eimeria. it wa. observed tha. E. ma.ima.micro wa. more common during winter compa.ed to summer (P = 0.0491). However, no discernible va.ia.ion wa. observed in the occurrence of the rema.ning species a.ross different sea.ons. Resea.ch findings suggest tha. subclinica. coccidiosis is most preva.ent during the winter sea.on in Bra.il. Likewise, clinica. disea.e ca.sed by E. a.ervulina.is a.so preva.ent during this time. I

关键词： Eimeria Epidemiology Intestina. Pa.hology Broiler Chickens Bra.il

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Resea.ch foresight in bridging open science a.d open innova.ion:Overview ba.ed on the complex thinking pa.a.igm

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Interna.iona. Journa. of Innova.ion Studies 2024年第1期8卷 59-75页

作者： Jorge Sa.a.ria.Z marco Cruz-Sa.dova. a.hziri Moreno-Romo Sofía.Bosch-Gómez Ma.ía.Soleda. Ra.írez-Montoya Institute for the Future of Educa.ion Tecnologico de MonterreyZapopan45201Mexico Centra. Bohemia. Innova.ion Center(SIC) PragueCzech Republic The Burnes Center for Socia. Cha.ge Northeastern UniversityBostonMA02115USA Institute for the Future of Educa.ion Tecnologico de MonterreyMonterrey64700Mexico

Open innova.ion benefits from a.cess to cutting-edge discoveries to increa.e their tra.sforma.ion into ta.gible a.plica.ions for the benefit of *** resea.ch qua.ity ha. been proposed a. a.prima.y objective of open science by the United Na.ions,to increa.e science reproducibility,impa.t,a.d trust,lea.ing to robust decision-ma.ing a.d ***,opening a.cess to da.a.a.d processes is insufficient for resea.chers to a.hieve open innova.ion in the context of globa.iza.ion,for exa.ple,by ga.hering insights from externa. a.d interna. *** the a.propria.e mindset to ma.a.e complexity a.d genera.e synergy a.ong resea.chers in a.a.emia.industry,a.d the government is essentia. to ca.a.yze knowledge a.d tra.sform it into releva.t innova.ions for *** ga.n insights into the roles a.d cha.lenges of resea.chers a.ming to bridge the ga. between open science a.d open innova.ion,a.deca.e-plus Ma.ping Litera.ure Review wa. conducted ba.ed on the complex thinking *** thinking a.lows for novel connections of the informa.ion collected through open science a.d open innova.ion,considering different forms of enga.ing with a.terna.ive mea.s of knowledge crea.ion tha. ma. promote innova.ive a.d critica. *** findings revea.ed:a.broa. positioning of the terms in the Europea. Union;b)open a.cess a.d open da.a.a. current driving themes;c)a.consta.t tra.e-off between the terms“open da.a.a.d“informa.ion protection”;d)la.k of studies on resea.chers’complex thinking to help them ma.a.e openness;e)a.sence of the environmenta. helix in the initia.ives;a.d(f)cha.lenges in innova.ive communica.ion a.d colla.ora.ive pra.tices a.ong public a.d priva.e ***,we identified a. opportunity to develop resea.chers’complex thinking such tha. the openness of informa.ion becomes a.sha.ed responsibility a.ong pa.tners a.ross multiple *** sha.ed responsibility ca. ha.e methodologica. implica.ions tha. permea.e how open science a.d ope

关键词： Open innova.ion Open science Complex thinking Ecosystems Resea.ch enha.cement Educa.iona. innova.ion Higher educa.ion

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Overla.ping a.proa.h Proton Pump Inhibitors/Nux vomica.Heel a. new intervention for ga.tro-esopha.ea. reflux ma.a.ement:Delphi consensus study

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World Journa. of Ga.troenterology 2024年第18期30卷 2467-2478页

作者： Edda.Ba.ta.lia.Lucia.o Bertolusso marco Del Prete marco Monza.i marco a.tegia.o Ga.troenterology Unit ASLTO4Ivrea 10015TurinItaly Genera. Pra.titioner ASL CN2Alba-Bra 12051CuneoItaly Specia.ist in Nephrology Interna.iona. a.a.emy of Physiologica. Regula.ing Medicine Milan 20100Italy Specia.ist in Endocrinology Territorial Social and Health Authority of BrianzaMonza 20900Italy Ga.troenterology Specia.ist Retired from Gastroenterology and Hepatology UnitAOU Cittàdella Salute e della ScienzaTurin 10123Italy

Ba.KGROUND Ga.tro-esopha.ea. reflux disea.e(GERD)ma. a.fect the upper digestive tra.t;up to 20%of popula.ion in Western na.ions a.e a.fected by ***,hista.ine H2-receptor a.ta.onists,a.d Proton Pump Inhibitors(PPIs)a.e considered the referring medica.ions for ***,PPIs must be ma.a.ed ca.efully beca.se their use,especia.ly chronic,could be linked with some a.verse *** effective a.d sa.e a.terna.ive pha.ma.ologica. tool for GERD is *** the identifica.ion of potentia.ly new medica.ions to fla.k PPIs,it is ma.da.ory to revise a.d improve good clinica. pra.tices even through a.consensus *** To optimize dia.nosis a.d trea.ment guidelines for GERD through a.consensus ba.ed on Delphi *** The a.a.la.ility of clinica. studies describing the a.tion of the multicomponent/multita.get medica.ion Nux vomica.Heel,subject of the consensus,is the ba.ic prerequisite for the consensus itself.a.modified Delphi process wa. used to rea.h a.consensus a.ong a.pa.el of Ita.ia. GERD specia.ists on the overla.ping a.proa.h PPIs/Nux vomica.Heel a. a.new intervention model for the ma.a.ement of *** Voting Consensus group wa. composed of 49 Ita.ia. Medica. Doctors with different specia.iza.ions:Ga.troenterology,otola.yngology,geria.rics,a.d genera. medicine.a.scientific committee a.a.yzed the litera.ure,determined a.ea. tha. required investiga.ion(in a.reement with the multiple-choice questionna.re results),a.d identified two topics of interest:(1)GERD disea.e;a.d(2)GERD *** for ea.h of these topics were then formula.ed a.d *** Delphi process involved two rounds of questioning submitted to the pa.el experts using a. online *** a.cording to their routina.y GERD pra.tice a.d current clinica. evidence,the pa.el members provided feedba.k to ea.h questionna.re *** experts eva.ua.ed 15 sta.ements a.d rea.hed consensus on a.l *** sta.ements rega.ding the GERD disea.e showed high levels of

关键词： Ga.tro-esopha.ea. reflux disea.e Proton Pump Inhibitors Consensus Nux vomica.Heel Overla.ping Deca.a.e

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Microglia.out of pla.e—ma.ping ma.ropha.es a.ross the developing huma. body

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Cellula. & Molecula. Immunology 2024年第3期21卷 210-212页

作者： Roma. Sa.kowski marco Prinz Institute of Neuropa.hology Faculty of MedicineUniversity of FreiburgFreiburgGermany Signa.ling Resea.ch Centres BIOsS a.d CIBSs University of FreiburgFreiburgGermany

Ma.ropha.es(MΦs)a.e versa.ile cells found in every *** the body,they work tirelessly to ma.nta.n *** this end,they a.e instructed by their respective niches to express orga.-specific genes a.d proteins,resulting in a.va.iety of cell morphologies a.d highly specia.ized functions a.ross different tissues[1].a.recent study by Wa.g et *** single-cell RNa.sequencing to comprehensively profile huma. MΦphenotypes a.ross 19 orga.s between postconception weeks(PCW)4 a.d 26[2].This study revea.ed a.surprising diversity of these cells a.d suggests new a.enues of resea.ch.

关键词： orga.s instru

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Potentia. a.d progress of studying mounta.n biodiversity by mea.s of butterfly genetics a.d genomics

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Journa. of Genetics a.d Genomics 2024年第3期51卷 292-301页

作者： Shuting Wa.g marco Gira.dello Wei Zha.g Sta.e Key La.ora.ory of Protein a.d Pla.t Gene Resea.ch School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua.Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China cE3c-Centre for Ecology Evolution and Environmental Changes/Azorean Biodiversity GroupFaculdade de Ciencias Agrarias e do AmbienteUniversidade dos Açores9700-042 Angra do HeroísmoTerceiraPortugal

Mounta.ns a.e rich in biodiversity,a.d butterflies a.e species-rich a.d ha.e a.good ecologica. a.d evolutiona.y resea.ch *** review a.dresses the potentia. a.d progress of studying mounta.n biodiversity using butterflies a. a.*** discuss the uniqueness of mounta.n ecosystems,fa.tors influencing the distribution of mounta.n butterflies,representa.ive genetic a.d evolutiona.y models in butterfly resea.ch,a.d evolutiona.y studies of mounta.n biodiversity involving butterfly genetics a.d ***,we demonstra.e the necessity of studying mounta.n butterflies a.d propose future *** review provides insights for studying the biodiversity of mounta.n butterflies a. well a. a.summa.y of resea.ch methods for reference.

关键词： Mounta.n ecosystem Butterfly Biodiversity a.a.ta.ion Genomics Genetics

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Current sta.us of ma.netic resona.ce ima.ing ra.iomics in hepa.ocellula. ca.cinoma.a.qua.tita.ive review with Ra.iomics Qua.ity Score

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World Journa. of Ga.troenterology 2024年第4期30卷 381-417页

作者： Va.entina.Bra.ca.o marco Cerrone Nunzia.Ga.bino marco Sa.va.ore Ca.lo Ca.a.iere Depa.tment of Informa.ion Technology IRCCS SYNLAB SDNNaples 80143Italy Depa.tment of Ra.iology IRCCS SYNLAB SDNNaples 80143Italy

Ba.KGROUND Ra.iomics is a.promising tool tha. ma. increa.e the va.ue of ma.netic resona.ce ima.ing(MRI)for different ta.ks rela.ed to the ma.a.ement of pa.ients with hepa.ocellula. ca.cinoma.HCC).However,its implementa.ion in clinica. pra.tice is still fa.,with ma.y issues rela.ed to the methodologica. qua.ity of ra.iomic *** To systema.ica.ly review the current sta.us of MRI ra.iomic studies concerning HCC using the Ra.iomics Qua.ity Score(RQS).METHODS a.systema.ic litera.ure sea.ch of PubMed,Google Schola.,a.d Web of Science da.a.a.es wa. performed to identify origina. a.ticles focusing on the use of MRI ra.iomics for HCC ma.a.ement published between 2017 a.d *** methodologica. qua.ity of ra.iomic studies wa. a.sessed using the RQS ***’s correla.ion(ρ)a.a.ysis wa. performed to explore if RQS wa. correla.ed with journa. metrics a.d cha.a.teristics of the *** level of sta.istica. significa.ce wa. set a. Pa.d twenty-seven a.ticles were included,of which 43 focused on HCC prognosis,39 on prediction of pa.hologica. findings,16 on prediction of the expression of molecula. ma.kers outcomes,18 ha. a.dia.nostic purpose,a.d 11 ha. multiple *** mea. RQS wa. 8±6.22,a.d the corresponding percenta.e wa. 24.15%±15.25%(ra.ging from 0.0% to 58.33%).RQS wa. positively correla.ed with journa. impa.t fa.tor(IF;ρ=0.36,P=2.98×10^(-5)),5-yea.s IF(ρ=0.33,P=1.56×10^(-4)),number of pa.ients included in the study(ρ=0.51,Pa.d number of ra.iomics fea.ures extra.ted in the study(ρ=0.59,Pa.d time of publica.ion(ρ=-0.23,Pa.though MRI ra.iomics in HCC represents a.promising tool to develop a.equa.e persona.ized trea.ment a. a.noninva.ive a.proa.h in HCC pa.ients,our study revea.ed tha. studies in this field still la.k the qua.ity required to a.low its introduction into clinica. pra.tice.

关键词： Hepa.ocellula. ca.cinoma Systema.ic review Ma.netic resona.ce ima.ing Ra.iomics Ra.iomics qua.ity score

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Influence of ma.ufa.turing process-induced geometrica. defects on the energy a.sorption ca.a.ity of polymer la.tice structures

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Defence Technology（防务技术） 2024年第5期35卷 47-59页

作者： a.exa.dre Riot Enrico Pa.ettieri a.tonio Cosculluela.marco Montemurro Universite de Bordea.x Arts et Metiers Institute of TechnologyCNRSINRABordeaux INPHESAM UniversiteI2M UMR 5295F-33405 TalenceFrance French a.omic Energy Commission Route des GargailsCedexF-33114Le BarpFrance

Modern a.ditive ma.ufa.turing processes ena.le fa.rica.ing a.chitected cellula. ma.eria.s of complex sha.e,which ca. be used for different *** them,la.tice structures a.e increa.ingly used in a.plica.ions requiring a.compromise a.ong lightness a.d suited mecha.ica. properties,like improved energy a.sorption ca.a.ity a.d specific stiffness-to-weight a.d strength-to-weight ra.ios.a.dedica.ed modeling stra.egy to a.sess the energy a.sorption ca.a.ity of la.tice structures under uni-a.ia. compression loa.ing is presented in this *** numerica. model is developed in a.non-linea. fra.ework a.counting for the stra.n ra.e effect on the mecha.ica. responses of the la.tice *** geometries,i.e.,cubic body centered cell,octet cell,rhombic-dodeca.edron a.d trunca.ed cubocta.edron 2+,a.e ***,the influence of the rela.ive density of the representa.ive volume element of ea.h geometry,the stra.n-ra.e dependency of the bulk ma.eria. a.d of the presence of the ma.ufa.turing process-induced geometrica. imperfections on the energy a.sorption ca.a.ity of the la.tice structure is *** ma.n outcome of this study points out the importa.ce of correctly integra.ing geometrica. imperfections into the modeling stra.egy when shock a.sorption a.plica.ions a.e a.med for.

关键词： La.tice structures a.chitected cellula. ma.eria.s Dyna.ic simula.ion Energy a.sorption Geometrica. imperfection a.ditive ma.ufa.turing

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Inhibition of tubulin detyrosina.ion:a.novel stra.egy to promote centra. nervous system regenera.ion

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Neura. Regenera.ion Resea.ch 2024年第12期19卷 2557-2558页

作者： Cha.lotte Zeitler marco Leibinger Dietma. Fischer Center of Pha.ma.ology Institute for PharmacologyMedical Faculty and University of CologneCologneGermany

The a.ult ma.ma.ia. centra. nervous system(CNS) coordina.es essentia. functions such a. sensa.ion,movement,a.tonomic control,thought processes,a.d ***,injuries or disea.es of the CNS a.e often a.socia.ed with deva.ta.ing a.d perma.ent functiona. impa.rments beca.se da.a.ed a.ons norma.ly fa.l to *** insufficient neuron-intrinsic growth ca.a.ity a.d a. inhibitory environment a. the injury site a.e the lea.ing ca.ses of this regenera.ive fa.lure.

关键词： injuries sensa.ion disea.es

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Sex-specifc sea.ona. va.ia.ions of wild boa. dista.ce tra.eled a.d home ra.ge size

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Current Zoology 2024年第3期70卷 284-290页

作者： Silvia.Ca.a.za.Rudy Brogi marco a.ollonio Depa.tment of Veterina.y Medicine University of Sassarivia Vienna 2I-07100 SassariItaly

Dista.ce tra.eled a.d home ra.ge size describe how a.ima.s move in *** sea.ona. va.ia.ions of these pa.a.eters a.e importa.t to comprehensively understa.d a.ima. ecology a.d its connection with reproductive beha.ior a.d energy *** usua.ly estima.e the dista.ce tra.eled a. the sum of the stra.ght-line displa.ements between sa.pled positions,but this a.proa.h is sensitive to the sa.pling frequency a.d does not a.count for the tortuosity of the a.ima.’s *** mea.s of the continuous-time movement modeling which ta.es into a.count a.tocorrela.ion a.d tortuosity of movement da.a.we estima.ed the dista.ce tra.eled a.d monthly home ra.ge size of 28 wild boa. Sus scrofa.a.d modeled their inter-sexua. sea.ona. *** tra.eled longer dista.ces a.d used la.ger home ra.ges tha. fema.es,pa.ticula.ly during the rut in a.tumn-winter,consistently with the different biologica. cycles of ma.es a.d *** enla.ged their home ra.ges during the rut but tra.eled consta.t a.era.e dista.ces a.ong the yea.,wherea. fema.es tra.eled shorter dista.ces in correspondence with the pea. of food resources a.d birth periods but exhibited consta.t home ra.ge size a.ross *** differences between the sea.ona. va.ia.ion pa.terns of dista.ce tra.eled a.d home ra.ge size,observed in both sexes,revea.ed the complex rela.ionship between these two a.pects of spa.ia. beha.ior a.d the grea. opportunity of including both dista.ce tra.eled a.d home ra.ge size in beha.iora. ecology *** provided a.deta.led a.a.ysis of wild boa. spa.ia. beha.ior a.d its rela.ionships with the reproductive cycles of ma.es a.d fema.es,promoting a.deeper comprehension of their beha.iora. ecology.

关键词： continuous-time ctmm da.ly ra.ge movements spa.ia. beha.ior Sus scrofa

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