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Clinical and Evolutionary Characteristics of Pregnant and Postpartum Women with COVID-19 Admitted to a Hospital in the Central Region of Brazil

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Open Journal of Obstetrics and Gynecology 2022年第8期12卷 770-783页

作者： Eloísa Helena Kubiszeski Maria Aparecida Mazzutti Verlangieri Do Carmo Anselmo Verlangieri Do Carmo marcial francis galera Federal University of Mato Grosso Postgraduate Program in Health Sciences Faculty of Medicine Cuiabá Brazil Women’s Health Care Unit Júlio Müller University Hospital UFMT EBSERH Cuiabá Brazil Federal University of Mato Grosso Department of Gynecology and Obstetrics Faculty of Medicine Cuiabá Brazil Federal University of Mato Grosso Department of Pediatrics Faculty of Medicine Cuiabá Brazil

Objective: To describe the demographic and evolutionary characteristics of pregnant and postpartum women with coronavirus disease 2019 (COVID-19) admitted to a medium-sized hospital in Brazil. Method: This is a descriptive and retrospective study, collected from medical records, from March 2020 to October 2021 in a hospital located in Cuiabá (MT). Results: Pregnant and puerperal women with COVID-19 who needed hospitalization were mixed-race, from the metropolitan area, and carriers of moderate and severe forms of the disease. The primary risk condition found was overweight/obesity, and pre-gestational diabetes, hypertension, asthma, and autoimmune disease were the most prevalent comorbidities in the group. Elevated lactate dehydrogenase (LDH), c-reactive protein (CRP), and D-dimer were relevant laboratory findings in this group of patients. The most frequent maternal outcomes were respiratory failure, invasive ventilatory support, thromboembolic phenomena, sepsis, and preterm labor. Maternal death occurred in 6.4% of pregnant women. Most maternal deaths were of women who lived in the interior of the state, and the minority arrived on adequate ventilatory support. Prematurity and the need for neonatal intensive care unit (NICU) were significant complications for neonates. Stillbirth/neonatal mortality occurred in 11.0%. Conclusion: The clinical conditions at hospitalization were associated with worse living conditions and lack of access to health care, resulting in increased chances of severity and worsening outcomes in this group of women and neonates.

关键词： Analysis of Consequences Coagulation Disorders Coronavirus Disease 2019 Intensive Care Maternal Mortality Neonatal Outcomes Pregnancy SARS-CoV-2

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