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Stool DNA-based versus colonoscopy-based colorectal cancer screening: Patient perceptions and preferences

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Family medicine and Community Health 2015年第3期3卷 2-8页

作者： matthew V.Abola Todd F.Fennimore marcia m.chen Zhengyi chen Ashutosh K.Sheth Gregory Cooper Li Li Department of Family medicine and Community Health Case Western Reserve University School of Medicine11001 Cedar AvenueSuite 200ClevelandOH 44106USA Division of Gastroenterology University Hospitals Case Medical Center11100 Euclid AvenueClevelandOH 44106USA Case Comprehensive Cancer Center Case Western Reserve University School of Medicine10900 Euclid AvenueClevelandOH 44106USA Swetland Center for Environmental Health Case Western Reserve University11000 Cedar AvenueSuite 402ClevelandOH 44106USA

Objective:Stool DNA(sDNA)tests offer a noninvasive form of colon cancer screening for pa-tients,and although the test is expected to increase uptake of colon cancer screening,it is unknown if patients’perceptions of the sDNA test differ according to race and other patient ***:We conducted a self-administered survey of patients undergoing both a colonoscopy and an sDNA test to evaluate perceptions of sDNA ***:Of the 613 participants who were sent surveys,423 responded(69%response rate).Respondents self-identified as African American(n=127,30%),Caucasian(n=284,67%),and other ethnicity(n=12,3%).In general,participants found the sDNA test more suitable than a colonos-copy(n=309,75%).In univariate analyses,a higher percentage of Caucasians as compared with African Americans found the sDNA test more suitable than a colonoscopy(89%vs.76%,pmore Caucasians than African Americans preferred the sDNA test(43%vs.32%,pment for covariates reduced these racial differences to no significance.A family history of colo-rectal cancer remains a significant factor for patient’s preferences for screening regardless of ***:Our study shows no racial differences in the perception of and preference for sDNA testing for colon *** to increase the uptake of sDNA testing may help reduce racial disparities in colorectal cancer.

关键词： Colon cancer screening race stool DNA test patient perceptions

Cooperative Target Fencing of multiple Vehicles for a General Target with Connectivity Preservation and Collision Avoidance

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Journal of Systems Science & Complexity 2024年第1期37卷 136-151页

作者： PAN Zini chen Ben m Department of mechanical and Automation Engineering The Chinese University of Hong KongHong KongChina

In this paper,the authors study the cooperative target-fencing problem for n-dimensional systems and a target with a general *** using the velocity of the vehicles,a position feedback control law is proposed to fence the general target into the convex hull formed by the ***,the dynamics of each vehicle is described by a double-integrator *** potential functions are designed to guarantee connectivity preservation of the communication network and collision avoidance among the *** proposed approach can deal with a target whose trajectory is any twice continuously differentiable function of *** effectiveness of the result is verified by a numerical example.

关键词： multi-agent systems networked systems target fencing

A Survey on model Predictive Control of DFIGs in Wind Energy Conversion Systems

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CSEE Journal of Power and Energy Systems 2024年第3期10卷 1085-1104页

作者： Shuo Yan Junyu chen minghao Wang Yongheng Yang Jose m.Rodriguez STEm College RMIT UniversityMelbourneAustralia Hong Kong Polytechnic University Hong KongChina State Key Laboratory of Internet of Things for Smart City(Um) Department of Electrical and Computer EngineeringUniversity of MacaoMacaoChina College of Electrical Engineering Zhejiang UniversityHangzhou 310027China Universidad San Sebastin Campus BellavistaSantiago de ChileCLSantiago de Chile 000000Chile IEEE

This paper presents a comprehensive study on the model predictive control(mPC)of doubly fed induction generators(DFIG)in wind energy conversion systems(WECS);in particular the mPC of the rotor side *** general principle of prevalent mPC strategies is discussed to introduce the theoretical framework in the first ***,mainstream and high-performance mPC methods of DFIGs have been identified as model predictive current control(mPCC),model predictive torque control(mPTC),and model predictive power control(mPPC).Starting from analyzing dynamic models,these mPC strategies are investigated in terms of operating principles and technical *** paper further investigates implementation of mPC strategies in unbalanced *** on the quantitative and qualitative analysis of several case studies,performance of various mPC schemes is compared and their special features are *** for designing mPC strategies of DFIGs in WECS are provided.

关键词： Doubly fed induction generator(DFIG) model predictive control(mPC) wind energy

Semi-global leader-following consensus-based formation flight of unmanned aerial vehicles

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Chinese Journal of Aeronautics 2022年第1期35卷 31-43页

作者： Panpan ZHOU Ben m.chen Department of mechanical ami Automation Engineering The Chinese University of Hong KongHong KongChina

In this paper,we investigate a formation control problem of multi-agent systems(specifically a group of unmanned aerial vehicles)based on a semi-global leader-following consensus approach with both the leader and the followers subject to input *** the low gain feedback design technique,a distributed static control protocol and a distributed adaptive control protocol are *** former solves the problem under an assumption that the communication network is undirected,and it depends on the global information of the *** the latter,we relax the undirected graph to directed ***,an adaptive updating gain is designed to avoid using the global information of the communication *** is shown that the consensus protocols can solve the semi-global leader-following consensus problem if the leader agent is globally *** results are verified successfully by both simulation and real flight tests.

关键词： Consensus Formation flying Input saturation Low gain feedback multi-agent systems Unmanned aerial vehicles

Inhibition of protein degradation increases the Bt protein concentration in Bt cotton

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Journal of Integrative Agriculture 2024年第6期23卷 1897-1909页

作者： Yuting Liu Hanjia Li Yuan chen Tambel Leila.I.m Zhenyu Liu Shujuan Wu Siqi Sun Xiang Zhang Dehua chen Jiangsu Key Laboratory of Crop Genetics and Physiology/Co-Innovation Center for modern Production Technology of Grain Crops Yangzhou UniversityYangzhou 225009China Agricultural Research Cooperation Biotechnology and Biosafety Research CenterKhartoum 13314Sudan

Bacillus thuringiensis(Bt)cotton production is challenged by two main problems,i.e.,the low concentration of Bt protein at the boll setting stage and the lowest insect resistance in bolls among all the cotton plant’s ***,increasing the Bt protein concentration at the boll stage,especially in bolls,has become the main goal for increasing insect resistance in *** this study,two protein degradation inhibitors(ethylene diamine tetra acetic acid(EDTA)and leupeptin)were sprayed on the bolls,subtending leaves,and whole cotton plants at the peak flowering stage of two Bt cultivars(medium maturation Sikang 1(SK1))and early maturation Zhongmian 425(Zm425)in 2019 and *** Bt protein content and protein degradation metabolism were *** results showed that the Bt protein concentrations were enhanced by 21.3 to 38.8%and 25.0 to 38.6%in the treated bolls of SK1 and Zm425 respectively,while they were decreased in the subtending leaves of these treated *** the treated leaves,the Bt protein concentrations increased by 7.6 to 23.5%and 11.2 to 14.9%in SK1 and Zm425,*** combined application of EDTA and leupeptin to the whole cotton plant increased the Bt protein concentrations in both bolls and subtending *** Bt protein concentrations in bolls were higher,increasing by 22.5 to 31.0%and 19.6 to 32.5%for SK1 and Zm425,*** organs treated with EDTA or/and leupeptin showed reduced free amino acid contents,protease and peptidase activities and significant enhancements in soluble protein *** results indicated that inhibiting protein degradation could improve the protein content,thus increasing the Bt protein concentrations in the bolls or/and leaves of cotton ***,the increase in the Bt protein concentration without yield reduction suggested that these two protein degradation inhibitors may be applicable for improving insect resistance in cotton production.

关键词： Bt cotton Bt protein inhibition of protein degradation protein degradation metabolism

Applying machine Learning Approach to Explore Childhood Circumstances and Self-Rated Health in Old Age-China and the US,2020-2021

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China CDC weekly 2024年第11期6卷 213-218,I0008-I0013页

作者： Shutong Huo Derek Feng Thomas m.Gill Xi chen Department of Health Society&BehaviorPublic HealthUniversity of CaliforniaIrvineCAUSA Department of Statistics and Data Science Yale UniversityNew HavenCTUS Department of Internal medicine Yale School of MedicineNew HavenCTUS Department of Health Policy and management Yale School of Public HealthNew HavenCTUS Department of Economics Yale UniversityNew HavenCTUS.

Introduction:Childhood circumstances impact senior health,prompting the introduction of machine learning methods to assess their individual and collective contributions to senior ***:Using health and retirement study(HRS)and China Health and Retirement Longitudinal Study(CHARLS),we analyzed 2,434 American and 5,612 Chinese participants aged 60 and *** inference trees and forests were employed to estimate the influence of childhood circumstances on self-rated health(SRH).Results:The conventional method estimated higher inequality of opportunity(IOP)values in both China(0.039,accounting for 22.67%of the total Gini coefficient 0.172)and the US(0.067,accounting for 35.08%of the total Gini coefficient 0.191).In contrast,the conditional inference tree yielded lower estimates(China:0.022,accounting for 12.79%of 0.172;US:0.044,accounting for 23.04%of 0.191),as did the forest(China:0.035,accounting for 20.35%of 0.172;US:0.054,accounting for 28.27%of 0.191).Childhood health,financial status,and regional differences were key determinants of senior *** conditional inference forest consistently outperformed others in predictive accuracy,as demonstrated by lower out-of-sample mean squared error(mSE).Discussion:The findings emphasize the need for early-life interventions to promote health equity in aging *** learning showcases the potential in identifying contributing factors.

关键词： collective inequality estimates

Thin paints for durable and scalable radiative cooling

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Journal of Energy Chemistry 2024年第3期90卷 176-182,I0006页

作者： Shanquan Liu Fei Zhang Xingyu chen Hongjie Yan Wei chen meijie chen School of Energy Science and Engineering Central South UniversityChangsha 410083HunanChina School of Intelligent manufacturing Ecosystem Xi'an Jiaotong-Liverpool UniversitySuzhou 215400JiangsuChina

Passive daytime radiative cooling(PDRC) is environment-friendly without energy input by enhancing the coating's solar reflectance(R_(solar)) and thermal emittance(ε_(LWIR)) in the atmosphere's long-wave infrared transmission ***,high R_(solar) is usually achieved by increasing the coating's thickness,which not only increases materials' cost but also impairs heat ***,the desired high R_(solar) is vulnerable to dust pollution in the *** this work,a thin paint was designed by mixing hBN plates,PFOTS,and IPA. R_(solar)=0.963 and ε_(LWIR)=0.927 was achieved at a thickness of 150 μm due to the high backscattering ability of scatters.A high through-plane thermal conductivity(~1.82 W m^(-1) K^(-1)) also can be *** addition,the porous structure coupled with the binder PFOTS resulted in a contact angle of 154°,demonstrating excellent durability under dust *** experiments showed that the thin paint can obtain a 2.3℃ lower temperature for sub-ambient cooling than the reference PDRC coating in the ***,the above-ambient heat dissipation performance can be enhanced by spraying the thin paint on a 3D heat sink,which was 15.7℃ lower than the reference 1D structure,demonstrating excellent performance for durable and scalable PDRC applications.

关键词： Radiative cooling Heat dissipation Solar reflectance Thermal emittance Contact angle

Photodegradation of xylene isomers:Kinetics,mechanism,secondary pollutant formation potential and health risk evaluation

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Journal of Environmental Sciences 2024年第2期136卷 658-669页

作者： Xiaoyan chen Weikun Zhu Sufen Feng Jiangyao chen Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control Guangdong Technology Research Center for Photocatalytic Technology Integration and Equipment EngineeringInstitute of Environmental Health and Pollution ControlGuangdong University of TechnologyGuangzhou 510006China Guangzhou Key Laboratory of Environmental Catalysis and Pollution Control Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and HealthSchool of Environmental Science and EngineeringGuangdong University of TechnologyGuangzhou 510006China

Photodegradation technology has been widely applied in the purification of industrial aromatic ***,whether this technology efficiently removes the pollutants to prevent secondary pollution and health risk is still ***,the photodegradation processes of three xylenes were compared under designed reaction atmospheres and light *** lamp showed poor photodegradation ability toward xylenes,no matter in N_(2) or N_(2)+O_(2)system,while much higher photodegradation performance of xylenes were obtained under ultraviolet(UV)and vacuum ultraviolet(VUV)irradiation,especially in N_(2)+O_(2)+VUV system,where 97.9%of m-xylene,99.0%of o-xylene or 87.5%of p-xylene with the initial concentration of 860 mg/m^(3) was removed within 240 *** xylenes underwent three processes of photo-isomerization,photodecomposition and photo-oxidation to produce intermediates of aromatics,alkanes and *** them,the photo-isomerization products showed the highest concentration percentage(e.g.,≥50%in o-xylene system),confirming that photo-isomerization reaction was the dominated photodegradation process of ***,these isomerized products not only contributed about 97%and91%to the formation potential of O3(OFP)and secondary organic aerosols(SOAFP),but also displayed obvious non-carcinogenic risk,although one of photodecomposition product—benzene showed the highest occupational exposure ***,the secondary pollution and health risks of photodegradation products of xylenes were non-ignorable,although the OFP,SOAFP and health risks of the generated products reduced at least 4.5 times in comparison with that of the degraded *** findings are helpful for the appropriate application of this technology in the purification of industrial organic waste gas.

关键词： Isomer aromatics Photodegradation Ozone formation Secondary organic aerosols Health risk

Fe-N_(x) sites coupled with core-shell FeS@C nanoparticles to boost the oxygen catalysis for rechargeable Zn-air batteries

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Journal of Energy Chemistry 2024年第3期90卷 565-577,I0013页

作者： Katam Srinivas Zhuo chen Anran chen Fei ma ming-qiang Zhu Yuanfu chen School of Integrated Circuit Science and Engineering and State Key Laboratory of Electronic Thin Films and Integrated DevicesUniversity of Electronic Science and Technology of ChinaChengdu 610054SichuanChina College of mechanical and Electronic Engineering Northwest A&F UniversityYangling 712100ShaanxiChina School of materials and Energy Yunnan UniversityKunming 650091YunnanChina

The development of efficient single-atom catalysts(SACs) for the oxygen reduction reaction(ORR)remains a formidable challenge,primarily due to the symmetric charge distribution of metal singleatom sites(m-N_(4)).To address such issue,herein,Fe-N_(x) sites coupled synergistic catalysts fabrication strategy is presented to break the uniform electronic distribution,thus enhancing the intrinsic catalytic ***,atomically dispersed Fe-N_(x) sites supported on N/S-doped mesoporous carbon(NSC)coupled with FeS@C core-shell nanoparticles(FAS-NSC@950) is synthesized by a facile hydrothermal reaction and subsequent *** to the presence of an in situ-grown conductive graphitic layer(shell),the FeS nanoparticles(core) effectively adjust the electronic structure of single-atom Fe sites and facilitate the ORR kinetics via short/long-range coupling ***,FAS-NSC@950displays a more positive half-wave potential(E_(1/2)) of 0.871 V with a significantly boosted ORR kinetics(Tafel slope=52.2 mV dec^(-1)),outpacing the commercial Pt/C(E_(1/2)=0.84 V and Tafel slope=54.6 mV dec^(-1)).As a bifunctional electrocatalyst,it displays a smaller bifunctional activity parameter(ΔE) of 0.673 V,surpassing the Pt/C-RuO_(2) combination(ΔE=0.724 V).Besides,the FAS-NSC@950-based zincair battery(ZAB) displays superior power density,specific capacity,and long-term cycling performance to the Pt/C-Ir/C-based *** work significantly contributes to the field by offering a promising strategy to enhance the catalytic activity of SACs for ORR,with potential implications for energy conversion and storage technologies.

关键词： Fe-N_(x)sites Core-shell FeS@C Synergistic interactions Oxygen reduction reaction Zn-air battery