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New approach for particle size and shape analysis of iron-based oxygen carriers at multiple oxidation states

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Particuology 2024年第7期90卷 493-503页

作者： Victor Purnomo marcelo Dal Belo Takehara Robin Faust Lidiya Abdisa Ejjeta Henrik Leion Division of Energy and Materials Department of Chemistry and Chemical EngineeringChalmers University of TechnologyGöteborg 41258Sweden Division of Energy Science Department of Engineering Sciences and MathematicsLuleåUniversity of TechnologyLuleå97187Sweden

One of the crucial issues in the chemical looping technology lies in its bed material:the oxygen *** size analysis of an oxygen carrier is important since in a fluidized bed the material can only work well within a specific size *** the favorable size ranges for oxygen carrier materials have already been reported,none of the published studies has analyzed the particle size and shape of oxygen carriers in ***,the effect of oxygen carriers'oxidation degree on such properties has not been considered *** study aimed to report the particle size and shape analysis of five iron-based oxygen carriers,one natural ore,one synthetic material,and three residue products,at different oxidation degrees using dynamic image analysis(DIA).The oxygen carriers were prepared at different mass conversion degrees in a fluidized bed batch *** size distribution,sphericity,and aspect ratio of the oxygen carrier particles were examined experimentally using a Camsizer *** results show that the DIA method was successfully able to analyze the particle size and shape of our oxygen carriers with satisfying accuracy for *** oxidation state of the investigated materials seems to only affect the particle size and shape of oxygen carriers to a minor ***,exposures to redox cycles in a fluidized bed reactor may alter the particle size and shape of most oxygen carriers.

关键词： Oxygen carrier Size and shape analysis Dynamic image analysis Oxidation state Fluidized bed Chemical looping

Current role of extracorporeal membrane oxygenation for the management of trauma patients:Indications and results

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World Journal of Critical Care Medicine 2025年第1期14卷 42-48页

作者： Mohammed Abdulrahman Maryam Makki Malak Bentaleb Dana Khamis Altamimi marcelo AF Ribeiro Junior Department of Surgery College of Medicine and Health SciencesKhalifa UniversityAbu Dhabi 11001United Arab Emirates Department of Surgery Division of TraumaCritical Care and Acute Care SurgerySheikh Shakhbout Medical CityAbu Dhabi 11001United Arab Emirates Department of Surgery Sheikh Shakhbout Medical CityAbu Dhabi 91888ADUnited Arab Emirates Department of Surgery R Adams Cowley Shock Trauma CenterUniversity of MarylandBaltimoreMD 21201United States

Extracorporeal membrane oxygenation(ECMO)has emerged as a vital circulatory life support measure for patients with critical cardiac or pulmonary conditions unresponsive to conventional *** allows blood to be extracted from a patient and introduced to a machine that oxygenates blood and removes carbon *** blood is then reintroduced into the patient’s circulatory *** process makes ECMO essential for treating various medical conditions,both as a standalone therapy and as adjuvant ***-venous(VV)ECMO primarily supports respiratory function and indicates respiratory ***,veno-arterial(VA)ECMO provides hemodynamic and respiratory support and is suitable for cardiac-related *** study reviews recent literature to elucidate the evolving role of ECMO in trauma care,considering its procedural intricacies,indications,contraindications,and associated ***,the use of ECMO in trauma patients,particularly for acute respiratory distress syndrome and cardiogenic shock,has demonstrated promising outcomes despite challenges such as anticoagulation management and complications such as acute kidney injury,bleeding,thrombosis,and *** studies have shown that VV ECMO was associated with significantly higher survival rates than conventional mechanical ventilation,whereas other studies have reported that VA ECMO was associated with lower survival rates than VV *** plays a critical role in managing trauma patients,particularly those with acute respiratory *** research is necessary to explore the full potential of ECMO in trauma *** should have a clear understanding of the indications and contraindications for the use of ECMO to maximize its benefits in treating trauma patients.

关键词： Extracorporeal membrane oxygenation treatments Multiple trauma Respiratory distress syndrome Cardiogenic shock Contraindications Anticoagulants

Determining future high speed rail review topics through bibliometric analysis

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High-Speed Railway 2024年第1期2卷 17-29页

作者： Heather Steele marcelo Blumenfeld Paul Plummer Birmingham Centre for Railway Research and Education School of Engineering University of BirminghamBirmingham B152TTUK

As High Speed Rail(HSR)has proliferated globally,so has a related research field dedicated to exploring and addressing its unique ***,studies to understand and classify the HSR research domain are *** paper addresses the gap,using bibliometric analysis to identify future research areas and 20 candidate topics for literature review based on keyword analysis through *** and review papers related to HSR published in the last 20 years(2003-2022)were retrieved from Scopus,and then analyzed to determine the split in knowledge between languages,the collaboration between countries and institutions,highly productive and cited journals,and research topics which have and have not been *** 30%of the search results were published exclusively in Chinese,highlighting the importance of extending the evaluation to cover both *** is a novel aspect of the work,which has enabled the recognition of potential knowledge *** is recommended that future reviews incorporate works in both languages,possibly through international *** in China and other countries that are strong collaborators have been identified,as well as relevant,highly cited journals.

关键词： High speed rail Literature review Bibliometric analysis Vosviewer Keyword co-occurrence

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巴西构造应力场的遗传有限单元法反演

地球物理学报 2000年第2期43卷 166-174页

作者：石耀霖 marcelo Assumpcao 中国科学技术大学研究生院北京100039 Institute of Astronomy and Geophysics University of Sao Paulobrazil01065

基于观测的主应力方位资料，应用遗传有限单元法对巴西及邻区边界位移和板内力源进行了反演，确认了前人的研究结果：板块边界作用是控制区域应力场的主要因素，山脉和海岸地形造成的扩展力是控制应力场的一个重要因素．同时显示了板块... 详细信息

基于观测的主应力方位资料，应用遗传有限单元法对巴西及邻区边界位移和板内力源进行了反演，确认了前人的研究结果：板块边界作用是控制区域应力场的主要因素，山脉和海岸地形造成的扩展力是控制应力场的一个重要因素．同时显示了板块在垂直载荷下的弯曲对局部水平应力场造成相当的影响．反演结果也表明，除了过去公认的东西向挤压作用外，巴西还受到相当明显的南北向构造作用．它的存在与最近ＧＰＳ资料的分析是一致的．研究还表明遗传有限单元法是偏微分方程反演问题求解的一种有效方法．

关键词：构造应力场地球物理反演问题巴西遗传有限元

Metabolomic fingerprinting of porcine lung tissue during pre-clinical prolonged ex vivo lung perfusion using in vivo SPME coupled with LC-HRMS

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Journal of Pharmaceutical Analysis 2022年第4期12卷 590-600页

作者： Nikita Looby Anna Roszkowska Aadil Ali Barbara Bojko marcelo Cypel Janusz Pawliszyn Department of Chemistry University of WaterlooWaterlooN2L 3G1Canada Department of Pharmaceutical Chemistry Medical University of Gdansk80-416GdanskPoland Division of Thoracic Surgery University Health NetworkTorontoM5G 2C4Canada Department of Pharmacodynamics and Molecular Pharmacology Faculty of PharmacyCollegium Medicum in BydgoszczNicolaus Copernicus University in Torun85-089BydgoszczPoland

Normothermic ex vivo lung perfusion(NEVLP)has emerged as a modernized organ preservation technique that allows for detailed assessment of donor lung function prior to *** main goal of this study was to identify potential biomarkers of lung function and/or injury during a prolonged(19 h)NEVLP procedure using in vivo solid-phase microextraction(SPME)technology followed by liquid chromatography-high resolution mass spectrometry(LC-HRMS).The use of minimally invasive in vivo SPME fibers for repeated sampling of biological tissue permits the monitoring and evaluation of biochemical changes and alterations in the metabolomic profile of the *** in vivo SPME fibers were directly introduced into the lung and were also used to extract metabolites(on-site SPME)from fresh perfusate samples collected alongside lung samplings.A subsequent goal of the study was to assess the feasibility of SPME as an in vivo method in metabolomics studies,in comparison to the traditional inlab metabolomics *** upregulated biochemical pathways involved in pro-and antiinflammatory responses,as well as lipid metabolism,were observed during extended lung perfusion,especially between the 11th and 12th hours of the procedure,in both lung and perfusate ***,several unstable and/or short-lived metabolites,such as neuroprostanes,have been extracted from lung tissue in vivo using SPME ***-site monitoring of the metabolomic profiles of both lung tissues through in vivo SPME and perfusate samples on site throughout the prolonged NEVLP procedure can be effectively performed using in vivo SPME technology.

关键词： Normothermic ex vivo lung perfusion Solid phase microextraction Lung metabolomics

The “Brain Stress Timing” phenomenon and other misinterpretations of randomized clinical trial on aneurysmal subarachnoid hemorrhage

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Neural Regeneration Research 2019年第8期14卷 1364-1366页

作者： Rafael Martinez-Perez Natalia Rayo Agustin Montivero Jorge marcelo Mura Division of Neurosurgery Institute of Clinical Neurosciences Universidad Austral de Chile Valdivia Chile Division of Cerebrovascular and Skull Base Neurosurgery Institute of Neurosurgery Dr Asenjo Santiago Chile Western University London ON Canada

Clipping and coiling are currently the two alternatives in treatment of ruptured cerebral aneurysms. In spite of some meritorious analysis, further discussion is helpful to understand the actual state of art. Retreatment and rebleeding rates clearly favors clipping, although short-term functional outcome seems to be beneficial for clipping, while this different is not such if we perform the comparison at a longer follow up. Longterm follow ups and cost analysis are mandatory to have a clear view of the current picture in treatment of subarachnoid hemorrhage. Treatment strategy should be made by a multi-disciplinary team in accredited centers with proficient experience in both techniques.

关键词： sAH subarachnoid hemorrhage coiling clipping ruptured aneurysm timing intracranial

Comment on"Reversible 3D optical data storage and information encryption in photo-modulated transparent glass medium"

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Light(Science & Applications) 2022年第8期11卷 1933-1934页

作者： Gael Poirier marcelo Nalin Sidney J.L Ribeiro Younes Messaddeq Institute of Science and Technology Federal University of AlfenasCampus Poços de CaldasPoços de CaldasMGBrazil Institute of Chemistry São Paulo State University UNESPAraraquaraSPBrazil

Dear Editor,The development of reversible photochromic materials combining efficient writing/erasing properties, low-cost and environmentally friendly compositions is a breakthrough challenge and a subject of many research works in the last decades. In this perspective, transparent oxide glasses are promising since their production is ensured by a simple melt-quenching technique and a proper laser writing setup is able to give rise to a localized photochromic effect, opening opportunities for 3D optical data storage.

关键词： transparent since glasses

Tubulointerstitial injury and proximal tubule albumin transport in early diabetic nephropathy induced by type 1 diabetes mellitus

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BIOCELL 2017年第1期41卷 1-12页

作者： Maximiliano GIRAUD-BILLOUD Fernando EZQUER Javiera BAHAMONDE marcelo EZQUER IHEM Universidad Nacional de CuyoCONICETFacultad de Ciencias MédicasMendozaArgentina Centro de Medicina Regenerativa Facultad de Medicina Clínica AlemanaUniversidad del DesarrolloAvenida Las Condes 12438SantiagoChile

A decrease in the tubular expression of albumin endocytic transporters megalin and cubilin has been associated with diabetic nephropathy,but there are no comprehensive studies to date relating early tubulointerstitial injury and the effect of the disease on both transporters in type 1 diabetes mellitus(T1DM).We used eight-week-old male C57BL/6 mice divided into two groups;one of them received the vehicle(control group),while the other received the vehicle+200 mg/kg streptozotocin(T1DM).Ten weeks after the injection,we evaluated plasma insulin,enzymuria,urinary vitamin D-binding protein(VDBP),tubulointerstitial fibrosis and proximal tubule histology,markers of autophagy,and megalin and cubilin *** found a reduction in tubular protein reabsorption(albumin and VDBP as specific substances carried by both transporters)with increased tubulointerstitial injury,development of fibrosis,thickening of tubular basement membrane,and an increase in tubular cell *** was associated with a decrease in the renal expression of megalin and *** also observed an increase in the amount of cellular vesicles of the phagocytic system in the tubules,which could be linked to an alteration of normal intracellular trafficking of both receptors,thus affecting the normal function of transporters in early stages of diabetic *** diabetic animals,the added effects of tubulointerstitial injury,the decreases in megalin and cubilin expression,and an altered intracellular trafficking of these receptors,seriously affect protein reabsorption.

关键词： Albuminuria Megalin Cubilin Autophagy

Resampling in neural networks with application to spatial analysis

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Geo-Spatial Information Science 2022年第3期25卷 413-424页

作者： Bruno Póvoa Rodrigues Vinicius Francisco Rofatto marcelo Tomio Matsuoka Talita Teles Assunção Graduate Program in Agriculture and Geospatial Information Federal University of UberlândiaMonte CarmeloBrazil Institute of Geography Federal University of UberlândiaMonte CarmeloBrazil

In developing Artificial Neural Networks(ANNs),the available dataset is split into three categories:training,validation and ***,an important problem arises:How to trust the predic-tion provided by a particular ANN?Due to the randomness related to the network itself(architecture,initialization and learning procedure),there is usually no best *** this issue,we provide a framework,which captures the randomness related to the network *** idea is to perform several training and test trials based on the Jackknife resampling *** consists of iteratively deleting a single observation each time from the sample and recomputing the ANN on the rest of the sample ***,interval prediction is available instead of point *** proposed method was applied and tested using pH,Ca and P data obtained by analyzing 118 georeferenced soil *** results,based on the dataset size simulation,showed that 60%reduction in available dataset offers compatible accuracy in relation to full dataset,and therefore a higher cost of sampling in the field would not be *** re-sampling method spatially characterizes the points of greater or lesser accuracy and *** re-sampling method increased the success rate by using interval prediction instead of using the mean as the most probable *** we restrict it to the regression neural network model,the resampling method proposed can also be extended to other modern statistical tools,such as Kriging,Least Squares Collocation(LSC),Convolutional Neural Network(CNN),and so on.

关键词： Artificial Neural Network(ANN) data splitting resampling delete-1 Jackknife spatial analysis